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ASN06917370

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Catalog No. T26668Cas No. 837404-68-9
Alias ASN-06917370, ASN 06917370

ASN06917370 (Compound V) is a specific modulator of the orphan receptor GPR17 (Uracil Nucleotide/Cysteinyl Leukotriene Receptor), with an EC50 of 268 pM for [35S]GTPyS binding, and exhibits neuroprotective effects.

ASN06917370

ASN06917370

😃Good
Catalog No. T26668Alias ASN-06917370, ASN 06917370Cas No. 837404-68-9
ASN06917370 (Compound V) is a specific modulator of the orphan receptor GPR17 (Uracil Nucleotide/Cysteinyl Leukotriene Receptor), with an EC50 of 268 pM for [35S]GTPyS binding, and exhibits neuroprotective effects.
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1 mg$149-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
ASN06917370 (Compound V) is a specific modulator of the orphan receptor GPR17 (Uracil Nucleotide/Cysteinyl Leukotriene Receptor), with an EC50 of 268 pM for [35S]GTPyS binding, and exhibits neuroprotective effects.
SynonymsASN-06917370, ASN 06917370
Chemical Properties
Molecular Weight531.92
FormulaC24H21ClF3N7O2
Cas No.837404-68-9
SmilesO=C1N=C(NC2=C1N=NN2CC=3C=CC=CC3Cl)C4CCN(C(=O)NC5=CC=C(C=C5)C(F)(F)F)CC4
Relative Density.1.56 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 1 mg/mL (1.88 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8800 mL9.3999 mL18.7998 mL93.9991 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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