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ASN06917370

Name: ASN06917370
Brand: TargetMol
SKU: T26668
Price: 149 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T26668Cas No. 837404-68-9

Alias ASN-06917370, ASN 06917370

ASN06917370 (Compound V) is a specific modulator of the orphan receptor GPR17 (Uracil Nucleotide/Cysteinyl Leukotriene Receptor), with an EC50 of 268 pM for [35S]GTPyS binding, and exhibits neuroprotective effects.

ASN06917370

🥰Excellent

Catalog No. T26668Alias ASN-06917370, ASN 06917370Cas No. 837404-68-9

Pack Size	Price	Availability	Quantity
1 mg	$149	In Stock

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Product Introduction

Bioactivity

Description	ASN06917370 (Compound V) is a specific modulator of the orphan receptor GPR17 (Uracil Nucleotide/Cysteinyl Leukotriene Receptor), with an EC50 of 268 pM for [35S]GTPyS binding, and exhibits neuroprotective effects.
Synonyms	ASN-06917370, ASN 06917370

Chemical Properties

Molecular Weight	531.92
Formula	C₂₄H₂₁ClF₃N₇O₂
Cas No.	837404-68-9
Smiles	O=C1N=C(NC2=C1N=NN2CC=3C=CC=CC3Cl)C4CCN(C(=O)NC5=CC=C(C=C5)C(F)(F)F)CC4
Relative Density.	1.56 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 1 mg/mL (1.88 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8800 mL	9.3999 mL	18.7998 mL	93.9991 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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