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Search Results for " il receptor "

20

Compounds

Cat No. Product Name Synonyms Targets
TP1422 Interleukin (IL)-6 Receptor Others
Interleukin (IL)-6 Receptor is a peptide.
T21629 Loxapine Dopamine Receptor , 5-HT Receptor
Loxapine is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent,used primarily in the treatment of schizophrenia. The drug is a member of the dibenzoxazepine class ...
T8692 (Rac)-Benpyrine TNF
(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.
T14369 AZD-0284 ROR
AZD-0284 is an inverse agonist of the nuclear receptor RORγ. In development for the treatment of plaque psoriasis vulgaris and respiratory tract disorders[1].
T1412 Loxapine succinate Daxolin,Loxapac,Cloxazepin,Loxapine succinate salt Dopamine Receptor , 5-HT Receptor
Loxapine succinate (Loxapac), a D2DR and D4DR inhibitor, is utilized in schizophrenia.
T2893 Muscone 3-Methylcyclopentadecanone,Methylexaltone MMP , TNF , NF-κB , NOD-like Receptor (NLR) , P-gp , Interleukin
Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.
T8828 CP 424174 IL Receptor
CP 424174 is an inhibitor of IL-1β post-translational processing with IC50 of 210 nM. Inhibits the formation of mature IL-1β. Indirectly inhibits NLRP3. Active in vivo and orally bioavailable.
T40423 L48H37
L48H37 is a chemically stable analog of Curcumin. It exhibits potent inhibitory properties against myeloid differentiation protein 2 (MD2), acting as a specific inhibitor. Its mechanism involves inhibiting the interactio...
T5094 IRAK inhibitor 1 IRAK , JNK
IRAK inhibitor 1 is an effective IRAK-4 inhibitor (IC50: 216 nM), is poorly active against JNK-1 (IC50: 3.801 μM) and JNK-2 (IC50>10 μM).
T5110 IRAK inhibitor 6 IRAK
IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK-4, IC50: 160 nM).
T4140 IRAK4-IN-1 IRAK
IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM.
T9027 CA-4948 Emavusertib IRAK , FLT
CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.
T4050 GSK2981278 ROR gama modulator 1 ROR
GSK2981278 (ROR gama modulator 1) is a highly potent and selective inverse agonist of retinoic acid receptor-related orphan receptor gamma (ROR gamma).
T9631 IRAK-4 protein kinase inhibitor 2 IRAK
IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM).
T14367 AZ1495 IRAK , CDK , Haspin Kinase
AZ1495 is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. Which Shows activity in treatment of mutant MYD88L265P diffu...
T4299 AS-2444697 IRAK
AS-2444697 is an inhibitor of IRAK-4 (C50 = 21 nM). AS-2444697 exhibits renoprotective effects through anti-inflammatory action. AS-2444697 potently inhibits human and rat IRAK-4 activity.
TQ0167 Zimlovisertib PF-06650833,PF06650833 IRAK
Zimlovisertib (PF-06650833) is an effective, selective and orally active inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4) (IC50s: 0.2 and 2.4 nM in the cell and PBMC assay).
T11673 IRAK4-IN-4 IRAK , cGAS
IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.
T9203 JH-X-119-01 IRAK
JH-X-119-01 is a highly potent and selective covalent inhibitor of IRAK-1.
T8316 1V209 TLR7 agonist T7 TLR
1V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects.
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