pro-a

pro-asp TFA(85227-98-1 free base) (TLβ4) down-regulate skin inflammation in mouse skin.

FA-Leu-Gly-Pro-Ala-OH is a synthetic peptide and a specific collagenase substrate, widely used in biochemical experiments and drug synthesis research.

Pro-Adrenomedullin(153-185),human, (C143H224N42O43), a peptide with the sequence H2N-SLPEAGPGRTLVSSKPQAHGAPAPPSGSAPHFL-OH, MW= 3219.6. Adrenomedullin (AM) is a ubiquitously expressed peptide initially isolated from phaechromyctoma in 19931. AM was initially identified as a vasodilator, some have cited this as the most potent endogenous vasodilatory peptide found in the body2. Differences in opinion regarding the ability of AM to relax vascular tone arises from the differences in the model system used3. Other effects of AM include increasing the tolerance of cells to oxidative stress and hypoxic injury and angiogenesis. AM is seen as a positive influence in diseases such as hypertension, myocardial infarction, chronic obstructive pulmonary disease and other cardiovascular diseases, whereas it can be seen as a negative factor in potentiating the potential of cancerous cells to extend their blood supply and cause cell proliferation.

Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys (Disulfide bridge: Cys1-Cys10), a decapeptide with a cyclic RGD active sequence, functions as an Integrin αIIbβ3 antagonist, effectively inhibiting platelet adhesion and proMMP-13 adhesion [1].

Z-Pro-Pro-aldehyde-dimethyl acetal is a potent prolyl endopeptidase (PREP) inhibitor, effectively impeding the activity of this cytoplasmic serine endoprotease with an IC50 of 12 nM. Its significance lies in its role in modulating cognitive dysfunction associated with aging and neurodegenerative conditions, such as Alzheimer's disease [1] [2].

H-Gly-Pro-Arg-Pro-NH2 is a tetrapeptide that mimics the N-terminal Gly-Pro-Arg sequence in the alpha (α) chain of fibrin, inhibiting its polymerization [1].

Tos-Gly-Pro-Arg-ANBA-IPA (acetate) is a peptide substrate used in luminescence measurement.

Tos-Gly-Pro-Arg-ANBA-IPA, a chromogenic peptide substrate, is utilized for the rapid and specific photometric assay of recombinant hirudin (r-hirudin).

D-Lys(Z)-Pro-Arg-pNA (diacetate) diacetate is a chromogenic substrate.

D-Lys(Z)-Pro-Arg-pNA is a luminescent substrate of activated protein C (APC).

c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-Agm is a highly efficient, selective, and short-acting peptide V2 receptor agonist (V2R), with EC50s of hV2R and rV2R being 0.25 and 0.05 nM, respectively.

pGlu-Pro-Arg-MNA [N-(3-[2-Furyl]-acryloyl) - L - leucyl - glycyl - p - nitroanilide] is a chromogenic peptide substrate, specifically utilized for its role in biochemical assays.

pGlu-Pro-Arg-MNA monoacetate, a thrombin substrate modeled after a thrombin cleavage site in human fibrinogen, can be used for sensitive assays of antithrombin III activity.

Pro-Adrenomedullin (N-20), rat is a polypeptide molecule with the sequence ARLDTSSQFRKKWNKWALSR-NH2.

The compound, tumor-targeted pro-apoptotic peptide (CNGRC-GG-D(KLAKLAK)2), functions as an anti-tumor agent by disrupting mitochondrial membranes to induce apoptosis, demonstrating anticancer efficacy in mice [1].

Prepro-ANF (56-92), human, a precursor to the human atrial natriuretic factor, activates guanylate cyclase by specifically enhancing particulate guanylate cyclase activity within the renal membrane and unit [1].

Prepro-Atrial Natriuretic Factor (26-55) (human) is a polypeptide that increases cyclic GMP levels in the renal cortex and medulla, and enhances renal guanylate cyclase activity [1].

Fmoc-L-Proline (Fmoc-Pro-OH) is a proline derivative.

Gap 27 is a peptide(Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile) derived from connexin 43 that is a selective gap junction blocker.

Acetyl Angiotensinogen (1-14), porcine Acetate is a peptide with the sequence AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH. The protein encoded by the Angiotensinogen gene is known as pre-angiotensinogen or angiotensinogen precursor.

Fmoc-Gly-Ser(psi(Me,Me)pro)-OH acetate is a dipeptide.

Fmoc-Gly-Thr(psi(Me,Me)pro)-OH is a polypeptide composed of glycine and threonine containing a (psi(Me,Me)pro) modification.

N-terminally acetylated Endomorphin-1 acetate (Ac-L-Tyr-L-Pro-L-Trp-L-Phe-CONH2) is a modified Endomorphin-1.

Diprotin A (TFA) is an inhibitor of dipeptidyl peptidase IV (DPP-IV).