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Tiger17 TFA

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Catalog No. T83744
Alias H-Trp-Cys-Lys-Pro-Lys-Pro-Lys-Pro-Arg-Cys-His-NH2

Tiger17, a cyclic peptide derivative of tigerinin-RC1 and tigerinin-RC2—antimicrobial peptides from the crab-eating frog (F. cancrivora) skin secretions—enhances HaCaT keratinocytes and human skin fibroblasts proliferation at 5 to 20 µg/ml concentrations, and promotes HaCaT cell migration at 20 µg/ml. Additionally, Tiger17 augments RAW 264.7 macrophages' recruitment and secretion of TGF-β1 and IL-6. When topically applied at 20 µg/ml, it accelerates wound closure and re-epithelialization in a mouse model of full-thickness dermal wounds.

Tiger17 TFA
Other Forms of Tiger17 TFA:
Tiger17TP26841647121-94-5
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Tiger17 TFA

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Catalog No. T83744Alias H-Trp-Cys-Lys-Pro-Lys-Pro-Lys-Pro-Arg-Cys-His-NH2
Tiger17, a cyclic peptide derivative of tigerinin-RC1 and tigerinin-RC2—antimicrobial peptides from the crab-eating frog (F. cancrivora) skin secretions—enhances HaCaT keratinocytes and human skin fibroblasts proliferation at 5 to 20 µg/ml concentrations, and promotes HaCaT cell migration at 20 µg/ml. Additionally, Tiger17 augments RAW 264.7 macrophages' recruitment and secretion of TGF-β1 and IL-6. When topically applied at 20 µg/ml, it accelerates wound closure and re-epithelialization in a mouse model of full-thickness dermal wounds.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$63InquiryInquiry
5 mg$235InquiryInquiry
10 mg$437InquiryInquiry
25 mg$932InquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
Tiger17, a cyclic peptide derivative of tigerinin-RC1 and tigerinin-RC2—antimicrobial peptides from the crab-eating frog (F. cancrivora) skin secretions—enhances HaCaT keratinocytes and human skin fibroblasts proliferation at 5 to 20 µg/ml concentrations, and promotes HaCaT cell migration at 20 µg/ml. Additionally, Tiger17 augments RAW 264.7 macrophages' recruitment and secretion of TGF-β1 and IL-6. When topically applied at 20 µg/ml, it accelerates wound closure and re-epithelialization in a mouse model of full-thickness dermal wounds.
SynonymsH-Trp-Cys-Lys-Pro-Lys-Pro-Lys-Pro-Arg-Cys-His-NH2
Chemical Properties
Molecular Weight1376.70
FormulaC62H97N21O11S2.XCF3COOH
SmilesO=C(N[C@H](C(N1[C@](CCC1)([H])C(N[C@H](C(N2[C@](CCC2)([H])C(N[C@H](C(N3[C@](CCC3)([H])C(N[C@H](C(N[C@@H](CSSC4)C(N[C@H](C(N)=O)CC5=CN=CN5)=O)=O)CCCNC(N)=N)=O)=O)CCCCN)=O)=O)CCCCN)=O)=O)CCCCN)[C@H]4NC([C@@H](N)CC6=CNC7=CC=CC=C67)=O.OC(C(F)(F)F)=O
SequenceH-Trp-Cys-Lys-Pro-Lys-Pro-Lys-Pro-Arg-Cys-His-NH2
Sequence ShortWCKPKPKPRCH
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: Soluble

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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