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Anti-IL-21 Antibody represents a highly specialized neutralizing monoclonal antibody specifically engineered to target the pro-inflammatory cytokine interleukin-21 (IL-21) with exceptional binding affinity. It effectively facilitates the measurable blockade of the IL-21/IL-21R signaling axis across various preclinical experimental models to evaluate the suppression of Th17/Tfh-mediated immune responses and the reduction of thyroid-specific autoantibodies during strictly monitored laboratory observation periods and functional immune cell assays.

| Description | Anti-IL-21 Antibody represents a highly specialized neutralizing monoclonal antibody specifically engineered to target the pro-inflammatory cytokine interleukin-21 (IL-21) with exceptional binding affinity. It effectively facilitates the measurable blockade of the IL-21/IL-21R signaling axis across various preclinical experimental models to evaluate the suppression of Th17/Tfh-mediated immune responses and the reduction of thyroid-specific autoantibodies during strictly monitored laboratory observation periods and functional immune cell assays. |
| In vitro | In primary thyroid cells and PBMCs from patients, Anti-IL-21 Antibody neutralized IL-21 and inhibited the expression of pro-inflammatory cytokines [1]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | IL-21 |
| Isotype | IgG1 |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
| Size | Quantity | Unit Price | Amount | Operation |
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