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Anti-IL-21 Antibody

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Catalog No. T9901A-1259

Anti-IL-21 Antibody represents a highly specialized neutralizing monoclonal antibody specifically engineered to target the pro-inflammatory cytokine interleukin-21 (IL-21) with exceptional binding affinity. It effectively facilitates the measurable blockade of the IL-21/IL-21R signaling axis across various preclinical experimental models to evaluate the suppression of Th17/Tfh-mediated immune responses and the reduction of thyroid-specific autoantibodies during strictly monitored laboratory observation periods and functional immune cell assays.

Anti-IL-21 Antibody

Anti-IL-21 Antibody

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Catalog No. T9901A-1259
Anti-IL-21 Antibody represents a highly specialized neutralizing monoclonal antibody specifically engineered to target the pro-inflammatory cytokine interleukin-21 (IL-21) with exceptional binding affinity. It effectively facilitates the measurable blockade of the IL-21/IL-21R signaling axis across various preclinical experimental models to evaluate the suppression of Th17/Tfh-mediated immune responses and the reduction of thyroid-specific autoantibodies during strictly monitored laboratory observation periods and functional immune cell assays.
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Product Introduction

Bioactivity
Description
Anti-IL-21 Antibody represents a highly specialized neutralizing monoclonal antibody specifically engineered to target the pro-inflammatory cytokine interleukin-21 (IL-21) with exceptional binding affinity. It effectively facilitates the measurable blockade of the IL-21/IL-21R signaling axis across various preclinical experimental models to evaluate the suppression of Th17/Tfh-mediated immune responses and the reduction of thyroid-specific autoantibodies during strictly monitored laboratory observation periods and functional immune cell assays.
In vitro
In primary thyroid cells and PBMCs from patients, Anti-IL-21 Antibody neutralized IL-21 and inhibited the expression of pro-inflammatory cytokines [1].
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
TargetIL-21
Chemical Properties
Antibody Information
IsotypeIgG1
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

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