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Anti-inflammatory agent 5w
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Catalog No. T212945 Copy Product Info
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Anti-inflammatory agent 5w is a investigational anti-inflammatory compound, its activity was tested by pro-inflammatory cytokine production. Consistent with results observed in HaCaT keratinocytes, ELISA analysis showed that Anti-inflammatory agent 5w significantly suppressed IL-6 secretion induced by 24-hour LPS stimulation. This inhibition was dependent on concentration and was already evident after a 3-hour pretreatment, with near-complete suppression at 1 μM, bringing IL-6 levels close to those seen in untreated control cells
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Product Introduction
Bioactivity
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Storage & Solubility Information
| Description | Anti-inflammatory agent 5w is a investigational anti-inflammatory compound, its activity was tested by pro-inflammatory cytokine production. Consistent with results observed in HaCaT keratinocytes, ELISA analysis showed that Anti-inflammatory agent 5w significantly suppressed IL-6 secretion induced by 24-hour LPS stimulation. This inhibition was dependent on concentration and was already evident after a 3-hour pretreatment, with near-complete suppression at 1 μM, bringing IL-6 levels close to those seen in untreated control cells |
| Molecular Weight | 360.09 |
| Formula | C14H10Cl2O2Se |
| Smiles | ClC1=CC=CC=C1\C=C\[Se](=O)(=O)C1=CC=CC=C1Cl |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Anti-inflammatory agent 5w chemical structure | Anti-inflammatory agent 5w formula | Anti-inflammatory agent 5w molecular weight
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