Search Result

Search Results for " bcl "

Targets

Libraries

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Compounds

Cat No.	Product Name
T38622	Bcl-xL antagonist 2		BCL
	Bcl-xL antagonist 2 is an effective and selective antagonist of Bcl-xL with an IC50 of 91 nM and a Ki of 65 nM. Bcl-xL a...		BCL
T77571	Bcl-B inhibitor 1		Apoptosis , BCL
	Bcl-B inhibitor 1 is a Bcl-B inhibitor with antitumor activity that binds to and inactivates pro-apoptotic proteins in t...		Apoptosis , BCL
T39961	Bcl-2-IN-2
	Bcl-2-IN-2 is a highly potent and selective inhibitor targeting Bcl-2 and Bcl-xL. It displays an IC50 value of 0.034 nM,...
T10483	Lisaftoclax	APG-2575,Bcl-2/Bcl-xl inhibitor 1	BCL
	Lisaftoclax is an oral dual inhibitor of Bcl-2 and Bcl-xl, with IC50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl, res...		BCL
T74298	Bcl-2-IN-5
	Bcl-2-IN-5 is a BCL-2 inhibitor with IC 50 s of 0.12 nM, 0.14 nM and 0.22 nM for Bcl-2 wild type, Bcl-2 D103Y and Bcl-2 ...
T74297	Bcl-2-IN-4
	Bcl-2-IN-4 is a potent, orally active and selective Bcl-2 inhibitor with an IC 50 of 1.5 nM. Bcl-2-IN-4 displays >200-fo...
T63757	Bcl-2-IN-9
	Bcl-2-IN-9 is a novel, pro-apoptotic, low cytotoxic Bcl-2 inhibitor (IC50: 2.9 μM). Bcl-2-IN-9 downregulates Bcl-2 expre...
T64053	Bcl-2-IN-8
	Bcl-2-IN-8 is a potent anti-cancer agent. bcl-2-IN-8 exhibits anti-proliferative effects on both drug-sensitive and drug...
T63676	Bcl-2-IN-6
	Bcl-2-IN-6 is a potent inhibitor of Bcl-2 (b-cell lymphoma-2) that downregulates Bcl-2 expression and increases the expr...
T63521	Bcl-2-IN-7
	Bcl-2-IN-7 is a potent inhibitor of Bcl-2 (b-cell lymphoma-2), which can downregulate the expression of Bcl-2, increase ...
T11968	MCL-1/BCL-2-IN-1		BCL
	MCL-1/BCL-2-IN-2 (Compound Nap-1) is a potent and selective dual inhibitor of Mcl-1 and Bcl-2 with IC 50 s of 4.45 and 3...		BCL
T11971	MCL-1/BCL-2-IN-4		Others
	MCL-1/BCL-2-IN-4 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor.		Others
T11969	MCL-1/BCL-2-IN-2		Others
	MCL-1/BCL-2-IN-2 is a potent and selective Bcl-2 and Mcl-1 dual inhibitor.		Others
T11970	MCL-1/BCL-2-IN-3		Others
	MCL-1/BCL-2-IN-3 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectiely.		Others
T74138	PROTAC Bcl-xL degrader-2
	PROTAC Bcl-xL degrader-2 is a potent Bcl-xL ( Bcl-2 family member) degrader based on von Hippel-Lindau ligand, with an I...
T73957	PROTAC Bcl-xL degrader-1
	PROTAC Bcl-xL degrader-1 is a PROTAC that comprises a Bcl-xL ( Bcl-2 family member) ligand binding group, a linker and a...
T74137	PROTAC Bcl-xL ligand-1
	PROTAC Bcl-xL ligand-1 is a ligand for Bcl-xL that can be used in the synthesis of PROTACs [1] .
T73999	PROTAC Bcl-xL degrader-3
	PROTAC Bcl-xL degrader-3 is a potent ROTAC Bcl-xL degrader (WO2020163823A2, compound 44) [1] .
T62249	Bcl-2/Mcl-1-IN-1
	Bcl-2/Mcl-1-IN-1 is an inhibitor of Bcl-2 (Ki: 4.53 μM) and Mcl-1 (Ki: 1.19 μM).Bcl-2/Mcl-1-IN-1 can be used in cancer r...
T62941	Bcl-2/Mcl-1-IN-3
	Bcl-2/Mcl-1-IN-3 is a Bcl-2/Mcl-1 inhibitor that acts on Mcl-1 (Ki: 0.14 μM) and Bcl-2 (Ki: 0.23 μM) and can be used in ...