T10101 |
Calcium channel-modulator-1
|
136941-70-3
|
98%
|
|
Calcium channel-modulator-1 is a calcium channel-modulator (IC50:0.8 μM) with specialisation to block aortic constriction.
|
T14064 |
8-Bromo-cGMP sodium
|
51116-01-9
|
98%
|
|
8-Bromo-cGMP sodium is a PKG activator, a membrane-permeable analog of cGMP. 8-Bromo-cGMP sodium has pain-relieving and vasodilatory effects, significantly inhib...
|
T27753 |
KT-362 fumarate
|
105394-80-7
|
98%
|
|
KT-362 fumarate is a novel compound that acts as an antagonist of calcium channels, potassium channels and sodium channels.KT-362 fumarate causes vasodilation by...
|
T73587 |
KT-362
|
93392-97-3
|
98%
|
|
KT-362 is a calcium channel blocker with antihypertensive properties that can be used in the study of cardiovascular disease.
|
T28164 |
Nexopamil
|
136033-49-3
|
98%
|
|
Nexopamil is a calcium channel antagonist and a 5-hydroxytryptamine 2A receptor antagonist. Nexopamil inhibits 5-HT-induced contraction and proliferation of mese...
|
T25372 |
EMD57033
|
147527-31-9
|
98%
|
|
EMD57033 is a cardiac troponin C (cTnC) activator, a dominant Ca2+ sensitizer, which functions by binding to cardiac/slow skeletal troponin C heterodimers to pro...
|
T41190 |
AY 77
|
1835734-92-3
|
98%
|
|
AY 77 is a potent and selective PAR2 agonist. AY 77 showed selectivity for Ca2+ and ERK1/2 signaling (ec50 value of Ca2+ release was 40 nM and ec50 value of ERK1...
|
T28974 |
Ticolubant
|
154413-61-3
|
98%
|
|
Ticolubant is orally active leukotriene B4 antagonist with high affinity for the human neutrophil LTB4 receptor (Ki = 0.78 nM), blocks LTB4-induced Ca2+ migrati...
|
T27087 |
Cronidipine
|
113759-50-5
|
98%
|
|
Cronidipine, a calcium channel antagonist, is used potentially for the treatment of hypertension and myocardia ischemia.
|
T3465L |
Vesnarinone HCl
|
T3465L
|
98%
|
|
Vesnarinone HCl is an orally active phosphodiesterase 3 (PDE3) inhibitor.Vesnarinone HCl modulates calcium and potassium ions, increasing calcium flux and decrea...
|
T19839 |
Oxatomide
|
60607-34-3
|
98%
|
|
Oxatomide is a potent and orally active dual H1 histamine receptor and P2X7 receptor antagonist with antihistamine and antiallergic activity.Oxatomide can be use...
|
T10874 |
CP-060
|
180090-15-7
|
98%
|
|
CP-060 is a potent Ca2+ antagonist and inhibits Ca2+ overload with antioxidant and cardioprotective activities.
|
T41233 |
Cis-22a
|
1819366-84-1
|
98%
|
|
Cis-22a is a TRPV6 inhibitor (IC50 = 0.32 μM), which exhibits selectivity against related TRPV channels and calcium channels. cis-22a displays antiproliferative ...
|
T25263 |
Clopimozide
|
53179-12-7
|
98%
|
|
Clopimozide acts as a calcium channel antagonist and inhibits [3H] nilandipine binding.Clopimozide is a novel and orally available long-acting antischizophrenic ...
|
T7285 |
Ionomycin
|
56092-81-0
|
98%
|
|
Ionomycin is an calcium ionophore and an antibiotic that binds calcium ions (Ca2+). It is produced by the bacterium Streptomyces conglobatus.It is used in resea...
|
T11731L |
JTV-519 Formate
|
|
98%
|
|
JTV-519 Formate is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA). JTV-519 Formate is also a partial agonist of ryanodine rece...
|
T36812 |
Linoleic Acid Amide
|
3999-01-7
|
98%
|
|
Linoleic Acid Amide is derived from linoleic acid and regulates Ca2+ flux by inhibiting the sarco/endoplasmic reticulum Ca2+-ATPase.
|
TN1338 |
7Beta-Hydroxycholesterol
|
566-27-8
|
98%
|
|
7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells...
|
TN3660 |
Cinnamyl caffeate
|
115610-32-7
|
98%
|
|
Cinnamyl caffeate has cardiovascular protective effects, it can increase H9c2 cellular antioxidant potential, decrease intracellular calcium ion ([Ca2+]i) level,...
|
TN3042 |
4-Hydroxycinnamamide
|
194940-15-3
|
98%
|
|
4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
|