Shopping Cart
- Remove All
Your shopping cart is currently empty
(4)
Proteases/Proteasome Proteases/ProteasomeMTP
MTP (Microsomal Triglyceride Transfer Protein) is an endoplasmic reticulum membrane protein primarily responsible for lipid transport and lipoprotein assembly. Expressed in liver, intestine, and adipocytes, MTP promotes lipoprotein maturation and secretion by transferring triglycerides and cholesterol esters to nascent lipoprotein particles. MTP regulates blood triglyceride and cholesterol levels, with its dysfunction implicated in various lipid metabolism disorders such as familial hypobeta-lipoproteinaemia and cardiovascular disease.
Dirlotapide
T15006481658-94-0In house
Dirlotapide (CP742033) is an intestinal selective microsomal triglyceride transfer protein (MTP) inhibitor. It reduces body weight in diabetic dogs.Dirlotapide reduces food intake in a dose-dependent manner, possibly by increasing the release of peptide YY into the circulation.
- $750
Size
QTY
Lomitapide
T6267182431-12-5
Lomitapide (AEGR-733) is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing dietary lipids and transferring triglycerides onto apolipoprotein B (apo-B) in the assembly of very-low-density lipoprotein.
- $59
Size
QTY
Lomitapide Mesylate
T2545202914-84-9
Lomitapide Mesylate (BMS-201038 mesylate) is a methanesulfonic acid form of lomitapide, a small molecule inhibitor of microsomal triglyceride transfer protein.
- $30
Size
QTY
Granotapide
T31992594842-13-4In house
Granotapide is a microsomal triglyceride transfer protein (MTP) inhibitor that treats and rather prevents atherosclerosis, coronary artery disease, metabolic syndrome, obesity, diabetes mellitus, prediabetes mellitus, and hypertension.
- $210
Size
QTY
KD-026
T27719913541-47-6
KD-026 (SLx 4090), a microsomal triglyceride transfer protein (MTP) inhibitor(IC50 = 8.0 nM), is used in type 2 diabetes studies.
- $74
Size
QTY
BMS-212122
T30506194213-64-4In house
BMS-212122 (UNII-0Z473OO6GB) is a potent inhibitor of microsomal triglyceride transfer protein (MTP) and has shown hypolipidemic effects in animal studies.BMS-212122 significantly reduced lipid content and monocyte-derived (CD68+) cells in atherosclerotic plaques.
- $350
Size
QTY
CP-346086
T39303186390-48-7
CP-346086 is a highly potent and orally bioavailable inhibitor of microsomal triglyceride transfer protein (MTP), exhibiting an IC50 value of 2.0 nM against both human and rodent MTP. This compound effectively reduces plasma levels of cholesterol and triglycerides when administered in vivo.
Inquiry
PF-02575799
T16158863491-70-7
PF-02575799 is an inhibitor of microsomal triglyceride transfer protein (MTP) (IC50: 0.77±0.29 nM).
- $1,820
Size
QTY
CP-346086 dihydrate
T386661262769-98-1
CP-346086 dihydrate is a potent, orally active inhibitor of microsomal triglyceride transfer protein (MTP), with an IC50 of 2.0 nM for both human and rodent MTP, effectively lowering plasma cholesterol and triglyceride levels in vivo.
- $970
Size
QTY
Implitapide Racemate
T10504177277-99-5
Implitapide Racemate, the racemate of Implitapide, is an inhibitor of microsomal triglyceride transfer protein (MTP).
- $1,970
Size
QTY
CP-319340(free base)
T13418186390-35-2
CP-319340 free base is an inhibitor of microsomal triglyceride transfer protein (MTP).
- $1,520
Size
QTY
Implitapide
T15570177469-96-4
Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).
- Inquiry Price
Size
QTY
Go to page 1
Page of 1
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.