psi

PSI is a proteasome inhibitor.

PSI-697 (P-Selectin Inhibitor) is an orally active P-selectin inhibitor with anti-inflammatory and anti-thrombotic effects, useful for studying cardiovascular diseases such as atherosclerosis.

PSI-6206 (RO 2433) (RO2433) is a selective HCV RNA polymerase inhibitor.

Fmoc-Gly-Ser(psi(Me,Me)pro)-OH acetate is a dipeptide.

Fmoc-Gly-Thr(psi(Me,Me)pro)-OH is a polypeptide composed of glycine and threonine containing a (psi(Me,Me)pro) modification.

PSI-6206 13C,D3 is the deuterium labeled PSI-6206. PSI-6206 (T2117) is a potent and selective HCV NS5B polymerase inhibitor.

PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977).

PSI-7409 tetrasodium is the pharmacologically active 5′-triphosphate metabolite of sofosbuvir (PSI-7977) that directly inhibits hepatitis C virus NS5B RNA-dependent RNA polymerase, with IC50 values of 1.6, 2.8, 0.7, and 2.6 μM against GT 1b_Con1, GT 2a_JFH1, GT 3a, and GT 4a NS5B polymerases, respectively, PSI-7409 tetrasodium is widely used to study antiviral mechanisms and genotype-specific polymerase inhibition.

Fmoc-Gly-Ser(psi(Me,Me)pro)-OH is a dipeptide [Glycine-Serine psi(Me,Me)pro] with an Fmoc (9-fluorenylmethyloxycarbonyl) protecting group.

Fmoc-Ile-Ser(psi(Me,Me)pro)-OH is a dipeptide characterized by the presence of an N-terminal Fmoc-protected isoleucine and a serine residue with a (psi(Me,Me)pro) modification.

Fmoc-Gln(Trt)-Thr(psi(Me,Me)pro)-OH is a dipeptide.

Fmoc-Gln(Trt)-Ser(psi(Me,Me)pro)-OH is a dipeptide.

Fmoc-Ala-Ser(psi(Me,Me)pro)-OH is a dipeptide.

Fmoc-Tyr(tBu)-Ser(psi(Me,Me)pro)-OH is a dipeptide comprised of Fmoc-protected tyrosine and serine residues, with tBu (tert-butyl) protecting the tyrosine and a psi(Me,Me)pro modification on the serine.

Fmoc-Trp(Boc)-Ser(psi(Me,Me)pro)-OH is a dipeptide.

Fmoc-Glu(OtBu)-Ser(psi(Me,Me)pro)-OH is a dipeptide.

Fmoc-Lys(Boc)-Thr(psi(Me,Me)pro)-OH is a dipeptide.

Fmoc-Asp(OtBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide consisting of N-(9-fluorenylmethoxycarbonyl)-L-aspartic acid β-tert-butyl ester and a threonine analogue incorporating a non-native proline mimic with dimethyl substitution at the pseudopeptide bond.

Fmoc-Asn(Trt)-Ser(psi(Me,Me)pro)-OH is a dipeptide.

Fmoc-Trp(Boc)-Thr(psi(Me,Me)pro)-OH is a dipeptide.

Fmoc-Asp(OtBu)-Ser(psi(Me,Me)pro)-OH is a dipeptide.

Fmoc-Lys(Boc)-Ser(psi(Me,Me)pro)-OH is a dipeptide composed of an Fmoc-protected lysine with a Boc group and a serine residue containing a pseudo-proline [psi(Me,Me)pro] modification.

Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide composed of Fmoc-protected glutamic acid with a tert-butyl ester side chain and threonine modified with a psi(Me,Me)pro residue.

Fmoc-Asn(Trt)-Thr(psi(Me,Me)pro)-OH is a dipeptide.