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  • Reactive Oxygen Species
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Results for "

oxygen

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  • Inhibitors & Agonists
    669
    TargetMol | Inhibitors_Agonists
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    10
    TargetMol | Compound_Libraries
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    30
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    230
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    TargetMol | Disease_Modeling_Products
L-Ascorbic acid
Vitamin C, L-Ascorbate, L(+)-Ascorbic acid, Ascorbic acid
T092850-81-7
L-Ascorbic acid (Vitamin C) is a natural product that is a potent reducing agent and antioxidant. L-Ascorbic acid functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen. L-Ascorbic acid is used in the treatment of scurvy.
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6α-Methoxygeniposidic acid
TN8537134515-70-1
6α-Methoxygeniposidic acid is a natural product that can be used in related research in the field of life sciences. Its product number is TN8537.
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7-10 days
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2'-Hydroxygenistein
TN27671156-78-1
2'-Hydroxygenistein is a naturally occurring flavonoid with a wide range of antioxidant, anti-inflammatory, anticancer, and anti-endometrial hyperplasia potentials.2'-Hydroxygenistein is a inhibitor of a variety of enzymes, including indole-3-acetic acid oxidase, α-glucosidase, β-glucuronidase, and lysozyme.
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Hydroxygenkwanin
Luteolin 7-methylether, 7-O-Methylluteolin
T4S009420243-59-8
1. Hydroxygenkwanin (Luteolin 7-methylether) possesses significant the antioxidative activity . 2. Hydroxygenkwanin has cytotoxicity, may be an effective natural product to treat glioma, and the combination of Apigenin and Hydroxygenkwanin may be a promising method for glioma chemotherapy.
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6-Hydroxygenistein-7-O-β-D-glucopyranoside
TN8416198135-88-5
6-Hydroxygenistein-7-O-β-D-glucopyranoside (compound 2) is a glucopyranoside extracted from Pueraria flower. Isoflavonoids from Pueraria flower are potential anti-inflammatory agents for microglial cells and can inhibit the production of NO.
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9-epi-6-Methoxygeniposidic acid
TN85081215178-87-2
9-epi-6-Methoxygeniposidic acid is a natural product that can be used in related research in the field of life sciences. Its product number is TN8508.
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7-10 days
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6-Hydroxygenistein
TN841513539-26-9
6-Hydroxygenistein is an isoflavone compound identified in Baptisia hirsuta.
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6α-Methoxygeniposide
TN8538135383-98-1
6α-Methoxygeniposide is a natural product that can be used in related research in the field of life sciences. Its product number is TN8538.
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7-10 days
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6-Ethoxygeniposide
TN31681264496-61-8
6-Ethoxygeniposide is a natural product for research related to life sciences. The catalog number is TN3168 and the CAS number is 1264496-61-8.
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(-)-Epigallocatechin Gallate
Epigallocatechol Gallate, EGCG
T2988989-51-5
(-)-Epigallocatechin Gallate (EGCG) is a phenolic antioxidant polyphenol flavonoid found in plants such as green and black tea, which inhibits telomerase and DNA methyltransferase, blocks the activation of EGF receptors and HER-2 receptors, inhibits cellular oxidation, and prevents free radical damage to cells.
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Rotenone
Rotocide, Rotenon, Paraderil, Dactinol, Barbasco
T297083-79-4
Rotenone (Rotocide) is a natural product and a botanical insecticide. Rotenone is a mitochondrial electron transport complex I inhibitor that promotes the production of reactive oxygen species in mitochondria and induces apoptosis.
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Quercetin
Sophoretin
T2174117-39-5
Quercetin, a flavonoid natural product, is a SIRT1 activator. It is also a PI3K inhibitor, inhibiting PI3Kγ, PI3Kδ, and PI3Kβ with IC50 values of 2.4, 3.0, and 5.4 μM, respectively. Recognized as a heat shock protein inhibitor, Quercetin can significantly reduce exosome release in TII models by downregulating Hsp70 or Hsp90.
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Acetylcysteine
N-Acetyl-L-cysteine, N-Acetylcysteine, N-Acetyl Cysteine, NAC, LNAC
T0875616-91-1
Acetylcysteine (NAC) is an N-acetyl derivative of cysteine, a ROS inhibitor and mucolytic agent. Acetylcysteine induces apoptosis, can be used to reduce mucus thickness, and has anti-influenza viral activity.
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Citronellol
dihydrogeraniol
T3240106-22-9
Citronellol ((±)-β-Citronellol) is used in insect repellents and perfumes and as a mite attractant.
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Trimethylamine N-oxide
T412451184-78-7
Trimethylamine N-oxide (TMAO) is a colorless amine oxide produced from choline, betaine, and carnitine via intestinal microbial metabolism that accumulates in tissues of marine animals and prevents the protein-damaging effects of urea.Trimethylamine N-oxide induces inflammation through activation of ROS NLRP3 inflammasomes, which can induce fibroblast differentiation and cardiac fibrosis.
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7-10 days
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Fusarochromanone
NSC-627608, NSC 627608, FC-101, FC101, FC 101
T24075802915-53-3In house
Fusarochromanone (FC-101) is a mycotoxin produced by Fusarium marcescens with potent antiangiogenic, anticancer and antimalarial activities. Fusarochromanone induces cell death in COS7 and HEK293 cells through activation of the JNK pathway.
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10-14 weeks
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Moracin C
TN194969120-06-5In house
Moracin C, a natural compound found in Morus mesozygia, Morus alba var. multicaulis, is an anti-inflammatory agent. moracin C inhibits nitric oxide (NO) release and LPS-activated reactive oxygen species (ROS) in cells.
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8-10 weeks
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Antroquinonol
T300871010081-09-0In house
Antroquinonol is a ubiquinone derivative from Antrodia camphorata with anti-inflammatory and anticancer activities.Antroquinonol reduces oxidative stress and inhibits inflammation and sclerosis in mice with focal segmental glomerulosclerosis through enhancement of the Nrf2 signaling pathway.Antroquinonol has potential for use in the treatment of non-small cell lung cancer. Antroquinonol has potential for the treatment of non-small cell lung cancer and may be used in colon cancer research.
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6-8weeks
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Ammonium formate
Formic acid ammonium salt
T5300540-69-2
Ammonium formate (Formic acid ammonium salt) is the simplest carboxylic acid. Formate is an intermediate in normal metabolism. It is responsible for both metabolic acidosis and disrupting mitochondrial electron transport and energy production by inhibiting cytochrome oxidase activity, the terminal electron acceptor of the electron transport chain. Cell death from cytochrome oxidase inhibition by formate is believed to result partly from depletion of ATP, reducing energy concentrations so that essential cell functions cannot be maintained. Furthermore, inhibition of cytochrome oxidase by formate may also cause cell death by increased production of cytotoxic reactive oxygen species (ROS) secondary to the blockade of the electron transport chain.
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Berberine hydrogen sulphate
Umbellatine Sulfate, Berberine Bisulfate
T5S0814633-66-9
Berberine hydrogen sulphate (Umbellatine Sulfate) , an alkaloid extracted from several plants, possesses antimicrobial activity against a wide variety of microorganisms including Gram-positive and Gram-negative bacteria, fungi, and protozoa.
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2'-Deoxyguanosine monohydrate
Guanine-2'-deoxyriboside
T4715312693-72-4
2'-Deoxyguanosine monohydrate (Guanine-2'-deoxyriboside) is a nucleoside consisting of the base guanine and the sugar deoxyribose. It is like guanosine, but with one oxygen atom removed. It is a nucleoside component of DNA. 2'-Deoxyguanosine monohydrate can be converted to 8-hydroxy-deoxyguanosine (8-OHdG) due to hydroxyl radical attack at the C8 of guanine. 8-OHdG is a sensitive marker of the DNA damage This damage, if left unrepaired, has been proposed to contribute to mutagenicity and cancer promotion.
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Acetyl-L-carnitine hydrochloride
O-Acetyl-L-carnitine hydrochloride, O-acetyl-L-carnitine hcl, O-Acetylcarnitine hcl, Acetyl L-carnitine hydrochloride
T25635080-50-2
Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) is a nutritional supplement composed of the hydrochloride salt form of the acetylated form of the endogenously produced L-carnitine, with potential neuroprotective, cognitive-enhancing, anti-depressive and immunomodulating activities. It may also relieve peripheral neuropathy induced by chemotherapy, diabetes or other diseases. In addition, acetyl-L-carnitine may modulate the immune response by increasing T-lymphocytes maturation and may downregulate pro-inflammatory cytokines in response to viruses, such as SARS-CoV-2. It may also disrupt the ACE2 signaling pathway and inhibit the production of reactive oxygen species (ROS).
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4-aminobenzoic acid
PABA, Vitamin H1, Vitamin Bx, para-Aminobenzoic acid
T1311150-13-0
4-aminobenzoic acid is an organic acid with UV-absorbing and antifibrotic properties. When exposed to light, 4-aminobenzoic acid absorbs UV light and releases excess energy through a photochemical reaction, which may cause DNA damage.4-aminobenzoic acid also increases oxygen uptake at the tissue level and may enhance monoamine oxidase (MAO) activity to promote serotonin degradation, which in excess may lead to fibrotic Changes.
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Arecoline
T6895363-75-2
Arecoline is a natural alkaloid derived from areca nut in the palm family and is a potent nicotine and partial agonist of muscarinic acetylcholine receptors. Arecoline has anti-anxiety and anti-parasitic activity, can induce oxidative stress and can be used to study Alzheimer's disease and Alzheimer's disease.
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6-8 weeks
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