d5

6-beta-Naloxol-D5 hydrochloride is a deuterium-labeled opioid antagonist, closely related to naloxone, that serves as an effective compound in the field of chemical research.

Bimatoprost-D5 is a deuterium-labeled Bimatoprost. Bimatoprost (T2538) is a topical hypotensive agent frequently used for treating glaucoma and ocular hypertension.

Blonanserin-D5 is a deuterium-labeled Blonanserin. Blonanserin (T1180) (AD-5423) is a dopamine D2/5-HT2 receptor antagonist with an atypical antipsychotic effect.

Enalapril-D5 maleate is deuterium labeled Enalapril maleate (TMSM-1101), which is an angiotensin converting enzyme (ACE) inhibitor.

Enalaprilat-D5 sodium is the deuterium labeled Enalaprilat, which is an angiotensin-converting enzyme (ACE) inhibitor.

Enalaprilat-D5 is the deuterium labeled Enalaprilat (T6340L), which is an angiotensin-converting enzyme (ACE) inhibitor.

Ethacrynic acid, a diuretic, functions as an inhibitor of L-type voltage-dependent and store-operated calcium channels, facilitating the relaxation of airway smooth muscle (ASM) cells. It exhibits anti-inflammatory effects, notably reducing retinoid-induced ear edema in mice, and inhibits glutathione S-transferases (GSTs), making it a potent suppressor of the NF-kB signaling pathway. Additionally, ethacrynic acid modulates leukotriene formation. A variant, Ethacrynic acid-D5, is distinguished by its deuterium labeling.

Idelalisib-D5, a version of Idelalisib (T8651) marked with deuterium, is an orally bioavailable and highly selective inhibitor of p110δ.

Ketorolac-D5 is a deuterated compound of ketorolac for isotope tracing. Ketorolac (T21412) is a non-steroidal anti-inflammatory agent and inhibitor of both COX-1 and COX-2.

Nateglinide-D5 is a deuterium labeled Nateglinide (TMSM-4588).

Nepafenac-D5 is the deuterium labeled Nepafenac (T1280), which is a selective inhibitor of COX-2 .

Nimesulide D5 is a deuterium-labeled derivative of the nonsteroidal anti-inflammatory drug (NSAID) nimesulide, and is used in pharmacokinetic, metabolic, and absorption studies. Nimesulide is a selective COX-2 inhibitor with an IC₅₀ value of 70 nM–70 μM. Nimesulide exhibits anti-inflammatory, analgesic, and antipyretic effects.

Phenindione-D5 is deuterium labeled Phenindione (T0514), which functions as a Vitamin K antagonist.

(Rac)-Apremilast-D5 is a deuterium-labeled version of the enantiomer (R)-Apremilast, also known as (R)-CC-10004, which itself is one specific form of Apremilast.

(rel)-Tranylcypromine-D5 hydrochloride is a deuterium labeled (rel)-Tranylcypromine hydrochloride. (rel)-Tranylcypromine hydrochloride is an irreversible, nonselective inhibitor of monoamine oxidase (MAO) used in the treatment of depression.

Solifenacin-D5 hydrochloride is a deuterium-labeled Solifenacin hydrochloride (T23379), which acts as an antagonist of muscarinic receptors with pKis of 7.6, 6.9, and 8.0 for M1, M2, and M3 receptors, respectively.

Tamoxifen-d5 is a deuterated form of Tamoxifen. Tamoxifen is an orally active selective estrogen receptor modulator (SERM) that blocks estrogen action in breast cells while activating estrogenic activity in other cells, such as those in bone, liver, and uterus. Tamoxifen is also a potent activator of Hsp90 and enhances the ATPase activity of the Hsp90 molecular chaperone.

Trandolapril-D5 is a deuterium labeled Trandolapril. Trandolapril (T5329) is an orally active inhibitor of angiotensin converting enzyme (ACE) for hypertension and congestive heart failure (CHF).

Trandolaprilate-D5 is a deuterium-labeled Trandolaprilate. Trandolaprilate (T20758) is an inhibitor of angiotensin-converting enzyme (ACE).

5-Hydroxy Propafenone-D5 hydrochloride is the deuterium labeled 5-Hydroxy Propafenone.

Mebeverine alcohol-D5 is the deuterium labeled Mebeverine alcohol (T11987).

Methocarbamol (T1409) is a central muscle relaxant. Methocarbamol-D5 is deuterium labeled Methocarbamol.

N-Desmethylnefopam-D5 hydrochloride is a deuterium labeled N-Desmethylnefopam hydrochloride.

O-desmethyl Mebeverine acid-D5 hydrochloride is the deuterium labeled O-desmethyl Mebeverine acid.