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Anti-human CD8 Antibody (2D51)

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Catalog No. TMAB-07421

Anti-human CD8 Antibody (2D51) is a Mouse antibody targeting human CD8. Anti-human CD8 Antibody (2D51) can be used in FCM.

Anti-human CD8 Antibody (2D51)

Anti-human CD8 Antibody (2D51)

😃Good
Catalog No. TMAB-07421
Anti-human CD8 Antibody (2D51) is a Mouse antibody targeting human CD8. Anti-human CD8 Antibody (2D51) can be used in FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 μg$3537-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-human CD8 Antibody (2D51) is a Mouse antibody targeting human CD8. Anti-human CD8 Antibody (2D51) can be used in FCM.
Ig Type
Mouse IgG1, k
Clone
2D51
Reactivity
Human
Application
FCM
Recommended Dose
FCM: 1μg/Test
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationMembrane; Single-pass type I membrane protein.
Tissue SpecificityMost prominently found in the gastrointestinal tract, skin, lung, and brain but not in liver.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4).
Concentration1mg/ml
Research BackgroundThe CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]
Antigen Details
Immunogen
Recombinant Protein: human CD8
Antigen Species
Human
Gene Name
CD8A
Gene ID
925
Protein Name
T-cell surface glycoprotein CD8 alpha chain
Uniprot ID
P01732
Function
Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.
Chemical Properties
Molecular WeightTheoretical: 27 kDa. Actual: 32-34 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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