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Anti-CD58 Antibody (7L828) is a Rabbit antibody targeting CD58. Anti-CD58 Antibody (7L828) can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $270 | 7-10 days |
Description | Anti-CD58 Antibody (7L828) is a Rabbit antibody targeting CD58. Anti-CD58 Antibody (7L828) can be used in WB. |
Alias | LFA3, CD58 molecule, CD58 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 7L828 |
Reactivity | Human |
Verified Activity | Anti-CD58 rabbit monoclonal antibody at 1:500 dilution. -Lane A: Raji Whole Cell Lysate. -Lane B: Jurkat Whole Cell Lysate. -Lane C: TF-1 Whole Cell Lysate. -Lane D: K562 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. |
Application | WB |
Recommended Dose | WB: 1:500-1:1000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human LFA-3 / CD58 (rh LFA-3 / CD58; TMPY-03489; AAH05930.1; Met1-Arg215). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | CD53 is a member of the transmembrane 4 superfamily, also called the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. Familial deficiency of CD53 gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
Conjucates | Unconjugated |
Immunogen | Recombinant Human LFA-3 / CD58 Protein (TMPY-03489) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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