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Anti-human CD57 Antibody (5R251)

Catalog No. TMAB-07413 Copy Product Info
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Anti-human CD57 Antibody (5R251) is a Mouse antibody targeting human CD57. Anti-human CD57 Antibody (5R251) can be used in FCM.

Anti-human CD57 Antibody (5R251)

Copy Product Info
🥰Excellent
Catalog No. TMAB-07413

Anti-human CD57 Antibody (5R251) is a Mouse antibody targeting human CD57. Anti-human CD57 Antibody (5R251) can be used in FCM.

Anti-human CD57 Antibody
(5R251)
Pack SizePriceUSA StockGlobal StockQuantity
100 μg$3547-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-human CD57 Antibody (5R251) is a Mouse antibody targeting human CD57. Anti-human CD57 Antibody (5R251) can be used in FCM.
Ig Type
Mouse IgM
Clone
5R251
Reactivity
Human
Verified Activity
scatter diagram showing peripheral blood lymphocytes stained with TMAB-07413. The cells were incubated with the antibody (TMAB-07413, 2µg/Test) for 30 min at 22°C. Acquisition of >10,000 events was performed.
Application
Recommended Dose
FCM: 2μg/Test
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationGolgi apparatus membrane; Single-pass type II membrane protein.
Tissue SpecificityMainly expressed in the brain.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4).
Research BackgroundThe protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
Antigen Details
Gene Name
B3GAT1
Gene ID
Protein Name
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1
Function
Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group.
Chemical Properties
Molecular WeightTheoretical: 38 kDa. Actual: 45 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze.
TransportShipping with blue ice.

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