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Anti-human CD57 Antibody (5R251) is a Mouse antibody targeting human CD57. Anti-human CD57 Antibody (5R251) can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μg | $354 | 7-10 days | 7-10 days |
| Description | Anti-human CD57 Antibody (5R251) is a Mouse antibody targeting human CD57. Anti-human CD57 Antibody (5R251) can be used in FCM. |
| Ig Type | Mouse IgM |
| Clone | 5R251 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 2μg/Test |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Golgi apparatus membrane; Single-pass type II membrane protein. |
| Tissue Specificity | Mainly expressed in the brain. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4). |
| Research Background | The protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008] |
| Gene Name | B3GAT1 |
| Gene ID | |
| Protein Name | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 |
| Function | Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group. |
| Molecular Weight | Theoretical: 38 kDa. Actual: 45 kDa. |
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. |
| Transport | Shipping with blue ice. |
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