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Anti-CD59 Antibody (3M173)
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Catalog No. TMAY-03808
Alias CD59 molecule, CD59
Anti-CD59 Antibody (3M173) is a Rabbit antibody targeting CD59. Anti-CD59 Antibody (3M173) can be used in FCM.
Anti-CD59 Antibody (3M173)
Anti-CD59 Antibody (3M173)
😃Good
Catalog No. TMAY-03808Alias CD59 molecule, CD59
Anti-CD59 Antibody (3M173) is a Rabbit antibody targeting CD59. Anti-CD59 Antibody (3M173) can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $269 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD59 Antibody (3M173) is a Rabbit antibody targeting CD59. Anti-CD59 Antibody (3M173) can be used in FCM. |
| Synonyms | CD59 molecule, CD59 |
| Ig Type | Rabbit IgG |
| Clone | 3M173 |
| Reactivity | Rat |
| Specificity | Rat CD59 |
| Verified Activity | Flow cytometric analysis of Rat CD59 expression on SD rat splenocytes. Cells were stained with purified anti-Rat CD59, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Rat CD59 (rR CD59; TMPY-03091; P27274; Met1-Asn100). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CD59 glycoprotein, also known as 2 kDa homologous restriction factor, HRF2, MAC-inhibitory protein, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIRL and CD59, is a cell membrane protein which contains one UPAR/Ly6 domain. CD59 is a small, highly glycosylated, GPI-linked protein, with a wide expression profile. The soluble form of CD59 from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. CD59 is a potent inhibitor of the complement membrane attack complex (MAC) action. CD59 was first identified as a regulator of the terminal pathway of complement. It acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. Defects in CD59 are the cause of CD59 deficiency (CD59D). |
| Conjucates | Unconjugated |
| Others Formats | APC/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Protein: Rat CD59 Protein (TMPY-03091) |
| Antigen Species | Rat |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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