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Anti-CD57 Antibody (4O28)
😃Good
Catalog No. TMAB-04030
Anti-CD57 Antibody (4O28) is a Mouse antibody targeting CD57. Anti-CD57 Antibody (4O28) can be used in IHC-P,IHC-Fr,IF.
Anti-CD57 Antibody (4O28)
Anti-CD57 Antibody (4O28)
😃Good
Catalog No. TMAB-04030
Anti-CD57 Antibody (4O28) is a Mouse antibody targeting CD57. Anti-CD57 Antibody (4O28) can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CD57 Antibody (4O28) is a Mouse antibody targeting CD57. Anti-CD57 Antibody (4O28) can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG1, k |
| Clone | 4O28 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Golgi apparatus membrane; Single-pass type II membrane protein. |
| Tissue Specificity | Mainly expressed in the brain. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Lyophilized or Liquid |
| Formulation | PBS, Glycerol, BSA. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human CD57 |
| Antigen Species | Human |
| Gene Name | B3GAT1 |
| Gene ID | |
| Protein Name | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 |
| Uniprot ID | |
| Function | Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group. |
| Molecular Weight | Theoretical: 38 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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