Home Tools
Log in
Cart

Search Result

Search Results for " transmembrane "

Targets

101

Compounds

8

Natural Products

1839

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T8868 4BP-TQS AChR
4BP-TQS is an allosteric agonist of α7 nAChRs.
T3135 KM11060 CFTR , Autophagy
KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasma membrane.
T1805 Ataluren PTC124 CFTR , Autophagy
Ataluren (PTC124) is a novel, orally administered drug that targets nonsense mutations. Ataluren is approved for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and olde...
T1634 Glibenclamide Glyburide Potassium Channel , Mitochondrial Metabolism , CFTR , P-gp , Autophagy
Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.
T9499 Icenticaftor QBW251 CFTR
Icenticaftor (QBW251) is an orally active potentiator of CFTR channel.
T16681 Nesolicaftor PTI-428 CFTR , Autophagy
Nesolicaftor (PTI-428) specifically enhances cystic fibrosis transmembrane conductance regulator protein synthesis.
T14935 Elexacaftor VX-445 CFTR , Autophagy
Elexacaftor (VX-445) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR) and it also facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface.
T5312 CFTR corrector 2 FDL169 CFTR , Autophagy
CFTR corrector 2 (FDL169) is a novel and potent CFTR (Cystic fibrosis transmembrane conductance regulator) corrector for treating cystic fibrosis (CF) patients who carry the F508del mutation.
T1874 PPQ-102 PPQ102,CFTR Inhibitor,PPQ 102 CFTR , Autophagy
PPQ-102 (CFTR Inhibitor), an effective CFTR inhibitor, can completely inhibit CFTR chloride current (IC50: 90 nM).
T2588 Ivacaftor Ivacaftor (VX-770),VX-770 CFTR , Autophagy
Ivacaftor (VX-770) (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR (EC50: 25 nM) in Fisher rat thyroid cells, respectively.
T10591 BPO-27 racemate BPO-27 (racemate) CFTR , Autophagy
BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM.
T2451 GlyH-101 GlyH 101 CFTR , Autophagy
GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of 1.4 uM.
T7083 GLPG1837 ABBV-974 CFTR , Autophagy
GLPG1837 (ABBV-974) is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.
T2486 IOWH-032 IOWH032,IOWH 032 CFTR , Autophagy
IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, diarrhea, and secretory diarrhea.
T2595 Lumacaftor VX-809,VRT 826809 CFTR , Autophagy
Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein. It enhances F508del-CFTR protein maturation in FRT cells (EC50: 100 nM).
T2355 CFTR(inh)-172 CFTRinh 172,CFTR Inhibitor-172,CFTRinh-172,CFTRinh172 CFTR , Autophagy
CFTR(inh)-172 (CFTR Inhibitor-172) is a voltage-independent, selective CFTR inhibitor.
TP1174 Endothelin-2 (49-69), human Human endothelin-2,Endothelin-2, human,Endothelin-2 (human, canine) Others
Endothelin-2 (49-69), human (Human endothelin-2) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.
T2263 Tezacaftor VX661 CFTR , Autophagy
Tezacaftor (VX661) is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.
T20341 DNDS CFTR
DNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).
T31014 Corrector C4 Corr 4a,Corrector C-4,Corr4a,Corrector C 4,Corr-4a Others
Corrector C4, a corrector commonly used to study cystic fibrosis mutants, works by alleviating the interaction between CFTR transmembrane domain mutants and protein homeostasis.
T63806 CFTR corrector 8 CFTR
CFTR corrector 8 is a highly effective modulator of the cystic fibrosis transmembrane conductance regulator (CFTR). This compound is specifically designed for utilization in research related to cystic fibrosis, a genetic...
T5345 V-9302 Others
V-9302 (V9302) is a competitive antagonist of transmembrane glutamine flux that selectively and potently targets the amino acid transporter ASCT2 (IC50: 9.6 uM).
T4168 Visomitin SKQ1 Reactive Oxygen Species
Visomitin (SKQ1) is a mitochondria-targeted antioxidant that decreases transmembrane potential and production of reactive oxygen species (ROS).
T26955 Cavosonstat N91115,N 91115,N-91115 GSNOR , CFTR
Cavosonstat (N91115) is an orally active S-nitrosoglutathione reductase (GSNOR) inhibitor that promotes cystic fibrosis transmembrane conductance regulator (CFTR) maturation and plasma membrane stabilization.Cavosonstat ...
T26630 Ani9 Ani 9,Ani-9,Apelin-12 acetate (229961-08-4 Free base) Chloride channel
Ani9 is a high selective blocker of Anoctamin1 (ANO1)/transmembrane protein 16A (TMEM16A) with an IC50 of 77 nM and can be used in studies about ANO1 and the treatment of ancer, hypertension, pain, diarrhea and asthma.
T60653 CFTR corrector 9 CFTR
CFTR Corrector 9, a cystic fibrosis transmembrane conductance regulator (CFTR) modulator, is employed in the research of cystic fibrosis (CF) and related CFTR-associated disorders [1].
T30293 Bamocaftor VX-659 CFTR
Bamocaftor is a CFTR channel (DeltaF508-CFTR mutation) corrector for CF transmembrane conductance regulators designed to restore F508del-CFTR protein function. Combined use of tezacaftor and VX-561 for the treatment of c...
T21662L Cadherin Peptide, avian Acetate Cadherin Peptide, avian Acetate (127650-08-2 Free base) Others
Cadherin Peptide, avian Acetate is a peptide with the sequence Leu-Arg-Ala-His-Ala-Val-Asp-Val-Asn-Gly-NH2. Cadherins are a class of type-1 transmembrane proteins.
T61483 GLP-1R modulator C5 Glucagon Receptor
GLP-1R modulator C5 is a small molecule GLP-1R orthosteric modulator that enhances GLP-1 binding to GLP-1R via transmembrane sites and can be used in the study of type II diabetes.
T68122 Oxmetidine SKF 92994,Oxmetidina,Oxmetidinum Histamine Receptor
Oxmetidine (SKF 92994) is a novel H2 receptor antagonist that is cytotoxic. Oxmetidine inhibits transmembrane calcium flux in cardiac and vascular tissues and is used in the treatment of active duodenal ulcers.
T12078 ML334 LH601A Nrf2
ML334 (LH601A) is a transmembrane and potent NRF2 activator that inhibits Keap1-NRF2 protein interactions to ameliorate myocardial infarction-induced cardiac fibrosis by inhibiting cardiac fibroblast activation and proli...
T77692 F7H Wnt/beta-catenin , Antibacterial
F7H is a potent Frizzled receptor FZD7 antagonist with an IC50 value of 1.25 μM.F7H is a potent ligand for the transmembrane structural domain (TMD) of FZD7, with potential antitumor and bacteriostatic activity.
T60085 MM3122 GTPL11533,MM-3122,Ac-GQFR-kbt SARS-CoV
MM3122 (MM-3122) is a selective type II transmembrane serine protease (TMPRSS2) inhibitor, IC50 = 0.34 nM. MM3122 effectively blocks TMPRSS2, thereby inhibiting the entry of SARS-CoV-2 and MERS-CoV into human cells.
T10776 CFTR corrector 4 CFTR
CFTR corrector 4 is a potent and orally available transmembrane conductance regulator (CFTR) for cystic fibrosis and is a potent (R,R) type active enantiomer. CFTR corrector 4 increases CFTR levels on the cell surface a...
T6825 Eltrombopag Olamine Promacta Olamine,Revolade,Eltrombopag diethanolamine salt,SB497115,SB-497115GR Thrombin
Eltrombopag Olamine (Eltrombopag diethanolamine salt) is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrom...
T67931 [Tyr3]Octreotate Others
[Tyr3]Octreotate is a long peptide compound containing 8 amino acids and is a functional DOTA chelating agent with covalent bonds. [Tyr3]Octreotate binds to transmembrane receptors of SSR2-active NETs and is actively tra...
T1146 Nifedipine BAY-a-1040,Procardia XL,Procardia,Adalat CaMK , Potassium Channel , Calcium Channel , Autophagy
Nifedipine (Procardia) is a dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation ...
T1006 Propantheline bromide Neopepulsan,Pro-Banthine,Neometantyl AChR
Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. Propantheline Bromide is the bromid...
T73599 TSPO ligand-1 Autophagy
TSPO ligand-1 has affinity for peripheral and central benzodiazepine receptors.TSPO ligand-1 is an AUTAC4-binding protein in the transmembrane domain of the outer mitochondrial membrane, which induces mitochondrial autop...
T38951 Isatuximab SAR-650984,hu38SB19,Isatuximab-irfc Apoptosis , CD38
Isatuximab is a monoclonal antibody targeting the transmembrane receptor and extracellular enzyme CD38 in malignant cells of the hematological system and is a highly expressed protein in multiple myeloma. Isatuximab has ...
T29040 UCCF-029 UC(CF)-029,UC(CF) 029,UCCF029,UC(CF)029
UCCF-029 is an activator of cystic fibrosis transmembrane conductance regulator (CFTR).
T23648 AF-2785
In epididymal epithelial cells, AF-2785 inhibits cystic fibrosis transmembrane conductance regulator Cl(-) channels.
T24095 PAPD5-IN-1 GNE9278,GNE 9278,GNE-9278
GNE-9278 is an NMDA receptor positive allosteric modulator. It acts via the transmembrane domain.
T71079 I 432
I 432 is a TMPRSS2 (transmembrane serine proteinase 2) inhibitor (Ki =0.9 nM).
T25898 Olacaftor VX 440,VX-440,VX440
Olacaftor, also known as VX-440, is a protein modulator of cystic fibrosis transmembrane regulator (CFTR).
T27098 Ivacaftor-D9 deutivacaftor,CTP-656
CTP-656, a cystic fibrosis transmembrane conductance regulator (CFTR) channel activator, is used potentially for the treatment of cystic fibrosis.
T39633 Navocaftor GLPG 3067,ABBV-3067
Navocaftor, as a cystic fibrosis transmembrane regulator ( CFTR ), is a protein modulator (US 20200377491 Al, example 1).
T16843 Saridegib IPI-926,Patidegib Others
Saridegib is an effective and specific inhibitor of Smoothened and a key signaling transmembrane protein in the Hedgehog pathway.
T13705 GLPG2451 Cysteine Protease
GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. It effectively potentiates low temperature rescued F508del CFTR (EC50: 11.1 nM).
T23656 VUF11211 VUF-11211,VUF 11211
VUF11211 is an effective antagonist of CXCR3 that acts by extending from the minor pocket into the major pocket of the transmembrane domains.

Compounds

4BP-TQS
T8868
Synonym:
Target: AChR
KM11060
T3135
Synonym:
Target: CFTR, Autophagy
Ataluren
T1805
Synonym: PTC124
Target: CFTR, Autophagy
Glibenclamide
T1634
Synonym: Glyburide
Target: Potassium Channel, Mitochondrial Metabolism, CFTR, P-gp, Autophagy
Icenticaftor
T9499
Synonym: QBW251
Target: CFTR
Nesolicaftor
T16681
Synonym: PTI-428
Target: CFTR, Autophagy
Elexacaftor
T14935
Synonym: VX-445
Target: CFTR, Autophagy
CFTR corrector 2
T5312
Synonym: FDL169
Target: CFTR, Autophagy
PPQ-102
T1874
Synonym: PPQ102,CFTR Inhibitor,PPQ 102
Target: CFTR, Autophagy
Ivacaftor
T2588
Synonym: Ivacaftor (VX-770),VX-770
Target: CFTR, Autophagy
BPO-27 racemate
T10591
Synonym: BPO-27 (racemate)
Target: CFTR, Autophagy
GlyH-101
T2451
Synonym: GlyH 101
Target: CFTR, Autophagy
GLPG1837
T7083
Synonym: ABBV-974
Target: CFTR, Autophagy
IOWH-032
T2486
Synonym: IOWH032,IOWH 032
Target: CFTR, Autophagy
Lumacaftor
T2595
Synonym: VX-809,VRT 826809
Target: CFTR, Autophagy
CFTR(inh)-172
T2355
Synonym: CFTRinh 172,CFTR Inhibitor-172,CFTRinh-172,CFTRinh172
Target: CFTR, Autophagy
Endothelin-2 (49-69), human
TP1174
Synonym: Human endothelin-2,Endothelin-2, human,Endothelin-2 (human, canine)
Target: Others
Tezacaftor
T2263
Synonym: VX661
Target: CFTR, Autophagy
DNDS
T20341
Synonym:
Target: CFTR
Corrector C4
T31014
Synonym: Corr 4a,Corrector C-4,Corr4a,Corrector C 4,Corr-4a
Target: Others
CFTR corrector 8
T63806
Synonym:
Target: CFTR
V-9302
T5345
Synonym:
Target: Others
Visomitin
T4168
Synonym: SKQ1
Target: Reactive Oxygen Species
Cavosonstat
T26955
Synonym: N91115,N 91115,N-91115
Target: GSNOR, CFTR
Ani9
T26630
Synonym: Ani 9,Ani-9,Apelin-12 acetate (229961-08-4 Free base)
Target: Chloride channel
CFTR corrector 9
T60653
Synonym:
Target: CFTR
Bamocaftor
T30293
Synonym: VX-659
Target: CFTR
Cadherin Peptide, avian Acetate
T21662L
Synonym: Cadherin Peptide, avian Acetate (127650-08-2 Free base)
Target: Others
GLP-1R modulator C5
T61483
Synonym:
Target: Glucagon Receptor
Oxmetidine
T68122
Synonym: SKF 92994,Oxmetidina,Oxmetidinum
Target: Histamine Receptor
ML334
T12078
Synonym: LH601A
Target: Nrf2
F7H
T77692
Synonym:
Target: Wnt/beta-catenin, Antibacterial
MM3122
T60085
Synonym: GTPL11533,MM-3122,Ac-GQFR-kbt
Target: SARS-CoV
CFTR corrector 4
T10776
Synonym:
Target: CFTR
Eltrombopag Olamine
T6825
Synonym: Promacta Olamine,Revolade,Eltrombopag diethanolamine salt,SB497115,SB-497115GR
Target: Thrombin
[Tyr3]Octreotate
T67931
Synonym:
Target: Others
Nifedipine
T1146
Synonym: BAY-a-1040,Procardia XL,Procardia,Adalat
Target: CaMK, Potassium Channel, Calcium Channel, Autophagy
Propantheline bromide
T1006
Synonym: Neopepulsan,Pro-Banthine,Neometantyl
Target: AChR
TSPO ligand-1
T73599
Synonym:
Target: Autophagy
Isatuximab
T38951
Synonym: SAR-650984,hu38SB19,Isatuximab-irfc
Target: Apoptosis, CD38
UCCF-029
T29040
Synonym: UC(CF)-029,UC(CF) 029,UCCF029,UC(CF)029
Target:
AF-2785
T23648
Synonym:
Target:
PAPD5-IN-1
T24095
Synonym: GNE9278,GNE 9278,GNE-9278
Target:
I 432
T71079
Synonym:
Target:
Olacaftor
T25898
Synonym: VX 440,VX-440,VX440
Target:
Ivacaftor-D9
T27098
Synonym: deutivacaftor,CTP-656
Target:
Navocaftor
T39633
Synonym: GLPG 3067,ABBV-3067
Target:
Saridegib
T16843
Synonym: IPI-926,Patidegib
Target: Others
GLPG2451
T13705
Synonym:
Target: Cysteine Protease
VUF11211
T23656
Synonym: VUF-11211,VUF 11211
Target:
1 2 3
Cat No. Product Name Synonyms Targets
TQ0312 Sphingomyelin Endogenous Metabolite
Sphingomyelin is a natural sphingolipid that existed in animal cell membranes. It implicates the regulation of transmembrane signaling.
T10065L 2',3'-cGAMP sodium 2'-3'-cyclic GMP-AMP sodium STING , cGAS
2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium), a cGAMP synthase (cGAS) affecting cytoplasmic DNA production as a second messenger, is a transmembrane bridging protein that is a key component of the cellular innate imm...
T3363 Jervine Iervin,11-Ketocyclopamine,Jerwiny Hedgehog/Smoothened , Smo
The biological activity of Jervine (Jerwiny) is mediated via its interaction with the 7 passes transmembrane protein Smoothened. Jervine binds with and inhibits smoothened, which is an integral part of the Hedgehog signa...
T14140 Agaric acid Agaricinic Acid Mitochondrial Metabolism , AChR
Agaricic acid is an adenine nucleotide translocase antagonist.It is obtained from various plants of the fungous tribe, i.e. Polyporus officinalis and Polyporus igniarius. Agaric acid (Agaricinic Acid) induces mitochondri...
TN1663 Ganoderic acid DM PARP , Androgen Receptor , CDK
Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 (NFATc1), this suppression leads to the inhibition of dendr...
TN2945 3-Hydroxybakuchiol ATPase , Caspase
3-Hydroxybakuchiol exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line and induces a decrease in the mitochondrial transmembrane potential, the activation of caspase-3, th...
TN4394 Kobophenol A MMP , BCL , p38 MAPK , NF-κB , ROS , DNA/RNA Synthesis , CDK , JNK
Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of inflammatory bone diseases relevant to osteoblast cell death. Kobophenol A inhibits AChE activity in a dose-depen...
T75540 Ipomoeassin F
Ipomoeassin F, a selective and potent inhibitor of endoplasmic reticulum (ER) protein translocation, targets the Sec61 complex's pore-forming subunit (Sec61α) at the ER membrane. It inhibits the ER membrane translocation...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-03014 Osteoactivin/GPNMB Protein, Mouse, Recombinant (His) Mouse HEK293
GPNMB belongs to the PMEL / NMB family, also known as Osteoactivin and Hematopoietic growth factor-inducible neurokinin 1 ( HGFIN ), is a transmembrane glycoprotein that is expressed in numerous cells, including osteocla...
TMPY-05586 CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent i...
TMPK-01069 TMEM106B Protein, Mouse, Recombinant (hFc) Mouse HEK293
TMEM106B is a well-recognised risk factor for FTD caused by GRN mutation. Elegant experiments have suggested that increased risk for FTD is due to elevated levels of TMEM106B (Nicholson et al, 2013; Gallagher et al, 2017...
TMPY-00147 TMEM156 Protein, Human, Recombinant (His) Human HEK293
TMPJ-01119 GPNMB Protein, Human, Recombinant (His) Human Human Cells
Osteoactivin is an intracellular glycoprotein belongs to the NMB/pMEL-17 family, which is asscociated with cell endosomal/lysomal compartments. Human Osteoactivin is a 560 amino acid type I transmembrane protein, and one...
TMPY-03410 TMEM25 Protein, Human, Recombinant (His) Human HEK293
TMEM25 is a novel member of the immunoglobulin superfamily. Immunoglobulin superfamily members are implicated in immune responses, growth factor signaling, and cell adhesion. TMEM25 contains 1 Ig-like (immunoglobulin-lik...
TMPY-04928 TMPRSS11B Protein, Human, Recombinant (His) Human HEK293
TMPY-00274 Enterokinase Protein, Bovine, Recombinant (His) Bovine Yeast
TMPY-02045 SECTM1 Protein, Human, Recombinant (His) Human HEK293
Secreted and transmembrane 1 (SECTM1), also known as K12, is a transmembrane and secreted protein with characteristics of a type 1a transmembrane protein of SECTM family. It is found in a perinuclear Golgi-like pattern a...
TMPY-04856 LRRTM2 Protein, Human, Recombinant (hFc) Human HEK293
LRRTM2 (Leucine-Rich Repeat Transmembrane Neuronal 2) is a Protein Coding gene. LRRTM2 belongs to the LRRTM family and is a key regulator of excitatory synapse development and function. It localizes to excitatory synapse...
TMPY-02012 A33 Protein, Human, Recombinant (His) Human HEK293
Cell surface A33 antigen, also known as glycoprotein A33, is a single-pass type I membrane protein that is expressed in the normal gastrointestinal epithelium and 95% of colon cancers. GPA33 contains one Ig-like C2-type ...
TMPY-04985 TMPRSS11D Protein, Human, Recombinant (His) Human HEK293
TMPRSS11D (HAT) belongs to the large type II transmembrane serine protease (TTSP) family, participating in various biological and physiological processes. TMPRSS11D protein expression in tumorous tissues were correlated ...
TMPY-01794 A33 Protein, Mouse, Recombinant (His) Mouse HEK293
Cell surface A33 antigen, also known as glycoprotein A33, is a single-pass type I membrane protein that is expressed in the normal gastrointestinal epithelium and 95% of colon cancers. GPA33 contains one Ig-like C2-type ...
TMPY-01655 LRRTM4 Protein, Human, Recombinant (His) Human HEK293
Leucine-rich repeat transmembrane neuronal protein 4, also known as LRRTM4, is a single-pass type I membrane protein that belongs to the LRRTM family. LRRTM4 is expressed in the limb mesenchyme, neural tube, caudal mesod...
TMPY-04823 LRRTM2 Protein, Human, Recombinant (His) Human HEK293
LRRTM2 (Leucine-Rich Repeat Transmembrane Neuronal 2) is a Protein Coding gene. LRRTM2 belongs to the LRRTM family and is a key regulator of excitatory synapse development and function. It localizes to excitatory synapse...
TMPY-03402 Osteoactivin/GPNMB Protein, Human, Recombinant (hFc) Human HEK293
GPNMB belongs to the PMEL / NMB family, also known as Osteoactivin and Hematopoietic growth factor-inducible neurokinin 1 ( HGFIN ), is a transmembrane glycoprotein that is expressed in numerous cells, including osteocla...
TMPY-02143 Osteoactivin/GPNMB Protein, Human, Recombinant (His) Human HEK293
GPNMB belongs to the PMEL / NMB family, also known as Osteoactivin and Hematopoietic growth factor-inducible neurokinin 1 ( HGFIN ), is a transmembrane glycoprotein that is expressed in numerous cells, including osteocla...
TMPY-04621 OSTM1 Protein, Mouse, Recombinant (His) Mouse HEK293
Osteopetrosis-associated transmembrane protein 1 (OSTM1) is a Single-pass type I membrane protein. It is expressed in many hematopoietic cells of the myeloid and lymphoid B- and T-lineages. The analysis of OSTM1 associat...
TMPY-03176 TMEM27 Protein, Human, Recombinant (hFc) Human HEK293
TMEM27 is a membrane protein. It has been proposed as a beta cell mass biomarker since it is cleaved and shed by pancreatic beta cells. Overexpression of TMEM27 leads to increased thymidine incorporation, whereas silenci...
TMPY-03365 TMEM27 Protein, Human, Recombinant (His) Human HEK293
TMEM27 is a membrane protein. It has been proposed as a beta cell mass biomarker since it is cleaved and shed by pancreatic beta cells. Overexpression of TMEM27 leads to increased thymidine incorporation, whereas silenci...
TMPY-00068 LRRTM4 Protein, Mouse, Recombinant (His) Mouse HEK293
Leucine-rich repeat transmembrane neuronal protein 4, also known as LRRTM4, is a single-pass type I membrane protein that belongs to the LRRTM family. LRRTM4 is expressed in the limb mesenchyme, neural tube, caudal mesod...
TMPY-01438 FLRT3 Protein, Human, Recombinant (His) Human HEK293
Leucine-rich repeat transmembrane protein FLRT3, also known as Fibronectin-like domain-containing leucine-rich transmembrane protein 3, and FLRT3, is a single-pass type I membrane protein which belongs to the fibronectin...
TMPY-02032 FLRT1 Protein, Human, Recombinant (His) Human HEK293
The three fibronectin leucine-rich repeat transmembrane (FLRT) proteins contain 10 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. FLRT1...
TMPY-03578 FLRT2 Protein, Mouse, Recombinant (His) Mouse HEK293
Fibronectin Leucine-Rich Transmembrane (FLRT) proteins are glycosylated membrane proteins expressed at the cell surface which localise in a homophilic manner to cell-cell contacts expressing the focal adhesion marker vin...
TMPY-04144 Kremen-1 Protein, Human, Recombinant (His) Human HEK293
KREMEN1 (Kringle Containing Transmembrane Protein 1) is a Protein Coding gene. This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (...
TMPY-00148 TMED9 Protein, Human, Recombinant (His) Human HEK293
TMPY-00089 TMIGD1 Protein, Human, Recombinant (His) Human HEK293
The transmembrane and immunoglobulin domain-containing 1 (TMIGD1) is a novel tumor suppressor that is highly expressed in normal renal tubular epithelial cells, but it is downregulated in human renal cancer. TMIGD1 is a ...
TMPY-05058 TMX1 Protein, Human, Recombinant (mFc) Human HEK293
As a thiol-based tumor suppressor, TMX1 increases mitochondrial ATP production and apoptosis progression. TMX1 is the first example of a topology-specific client protein redox catalyst acting both in the folding and in t...
TMPH-02595 Collectrin Protein, Mouse, Recombinant (His & Myc & SUMO) Mouse E. coli
Plays an important role in amino acid transport by acting as binding partner of amino acid transporters SLC6A18 and SLC6A19, regulating their trafficking on the cell surface and their activity. May also play a role in tr...
TMPY-04861 TMED1 Protein, Mouse, Recombinant (hFc) Mouse HEK293
TMED1 belongs to the EMP24/GP25L family. It contains 1 GOLD domain and is widely expressed. TMED1 binds to its receptor IL1RL1 and results in the activation of DNA binding by nuclear factor NF-kappa-B or transcription fr...
TMPY-02841 Fragilis/IFITM3 Protein, Human, Recombinant (mFc) Human HEK293
Interferon-induced transmembrane protein 3 (IFITM3) belongs to the CD225 family. To replicate, viruses must gain access to the host cell's resources. Interferon (IFN) regulates the actions of a large complement of interf...
TMPJ-01203 HATL5 Protein, Human, Recombinant (His) Human Human Cells
Transmembrane Protease Serine 11B (TMPRSS11B) is a single-pass type II membrane protein member of the peptidase S1 family. TMPRSS11B contains one peptidase S1 domain and one SEA domain. TMPRSS11B is a serine protease tha...
TMPY-00531 TMED9 Protein, Human, Recombinant (mFc) Human HEK293
TMPY-04872 TMIGD1 Protein, Human, Recombinant (mFc) Human HEK293
The transmembrane and immunoglobulin domain-containing 1 (TMIGD1) is a novel tumor suppressor that is highly expressed in normal renal tubular epithelial cells, but it is downregulated in human renal cancer. TMIGD1 is a ...
TMPY-01194 OSTM1 Protein, Human, Recombinant (His) Human HEK293
Osteopetrosis-associated transmembrane protein 1 (OSTM1) is a Single-pass type I membrane protein. It is expressed in many hematopoietic cells of the myeloid and lymphoid B- and T-lineages. The analysis of OSTM1 associat...
TMPY-02048 FLRT2 Protein, Human, Recombinant (His) Human HEK293
Fibronectin Leucine-Rich Transmembrane (FLRT) proteins are glycosylated membrane proteins expressed at the cell surface which localise in a homophilic manner to cell-cell contacts expressing the focal adhesion marker vin...
TMPJ-00436 PVRIG Protein, Cynomolgus, Recombinant (His) Cynomolgus Human Cells
PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) f...
TMPJ-00435 PVRIG Protein, Cynomolgus, Recombinant (hFc) Cynomolgus Human Cells
PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) f...
TMPJ-01238 VSTM2A Protein, Human, Recombinant (His) Human Human Cells
VSTM2A, also called VSTM2, is short for V-set and transmembrane domain-containing protein 2A. It is a 236 aa. protein which can be departed into two parts. The first 24 aa. is a signal peptide, and the last is a V-set an...
TMPJ-01318 TACI Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Tumor necrosis factor receptor superfamily member 13B, also known as TNFRSF13B or more commonly as TACI (transmembrane activator and CAML interactor), is a transmembrane receptor protein found predominantly on the surfac...
TMPY-03119 TMED1 Protein, Human, Recombinant (His) Human HEK293
TMED1 belongs to the EMP24/GP25L family. It contains 1 GOLD domain and is widely expressed. TMED1 binds to its receptor IL1RL1 and results in the activation of DNA binding by nuclear factor NF-kappa-B or transcription fr...
TMPY-03108 TMED1 Protein, Human, Recombinant (hFc) Human HEK293
TMED1 belongs to the EMP24/GP25L family. It contains 1 GOLD domain and is widely expressed. TMED1 binds to its receptor IL1RL1 and results in the activation of DNA binding by nuclear factor NF-kappa-B or transcription fr...
TMPH-00940 Anoctamin-5/ANO5 Protein, Human, Recombinant (E. coli, His) Human E. coli
Anoctamin-5/ANO5 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli.
TMPH-00939 Anoctamin-5/ANO5 Protein, Human, Recombinant (His) Human HEK293
Anoctamin-5/ANO5 Protein, Human, Recombinant (His) is expressed in HEK293.
TMPY-03970 TMUB2 Protein, Human, Recombinant (His) Human HEK293
TMPJ-00428 PVRIG Protein, Mouse, Recombinant (hFc) Mouse Human Cells
PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) f...
TMPY-05440 CD28H/TMIGD2 Protein, Human, Recombinant (hFc) Human HEK293
The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent i...
TMPH-02643 Enteropeptidase Protein, Mouse, Recombinant (His & Myc) Mouse HEK293
Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes in...
TMPY-04202 Tomoregulin-1 Protein, Mouse, Recombinant (hFc) Mouse HEK293
TMEFF1 is a novel transmembrane protein, containing two follisatin domains and an epidermal growth factor-like region. The ectopic expression of TMEFF1 in brain cancer cells resulted in their growth inhibition. That TMEF...
TMPH-02644 Enteropeptidase Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes in...
------------------------ More ------------------------
Osteoactivin/GPNMB Protein, Mouse, Recombinant (His)
TMPY-03014
Species: Mouse
Expression System: HEK293
CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-05586
Species: Human
Expression System: HEK293
TMEM106B Protein, Mouse, Recombinant (hFc)
TMPK-01069
Species: Mouse
Expression System: HEK293
TMEM156 Protein, Human, Recombinant (His)
TMPY-00147
Species: Human
Expression System: HEK293
GPNMB Protein, Human, Recombinant (His)
TMPJ-01119
Species: Human
Expression System: Human Cells
TMEM25 Protein, Human, Recombinant (His)
TMPY-03410
Species: Human
Expression System: HEK293
TMPRSS11B Protein, Human, Recombinant (His)
TMPY-04928
Species: Human
Expression System: HEK293
Enterokinase Protein, Bovine, Recombinant (His)
TMPY-00274
Species: Bovine
Expression System: Yeast
SECTM1 Protein, Human, Recombinant (His)
TMPY-02045
Species: Human
Expression System: HEK293
LRRTM2 Protein, Human, Recombinant (hFc)
TMPY-04856
Species: Human
Expression System: HEK293
A33 Protein, Human, Recombinant (His)
TMPY-02012
Species: Human
Expression System: HEK293
TMPRSS11D Protein, Human, Recombinant (His)
TMPY-04985
Species: Human
Expression System: HEK293
A33 Protein, Mouse, Recombinant (His)
TMPY-01794
Species: Mouse
Expression System: HEK293
LRRTM4 Protein, Human, Recombinant (His)
TMPY-01655
Species: Human
Expression System: HEK293
LRRTM2 Protein, Human, Recombinant (His)
TMPY-04823
Species: Human
Expression System: HEK293
Osteoactivin/GPNMB Protein, Human, Recombinant (hFc)
TMPY-03402
Species: Human
Expression System: HEK293
Osteoactivin/GPNMB Protein, Human, Recombinant (His)
TMPY-02143
Species: Human
Expression System: HEK293
OSTM1 Protein, Mouse, Recombinant (His)
TMPY-04621
Species: Mouse
Expression System: HEK293
TMEM27 Protein, Human, Recombinant (hFc)
TMPY-03176
Species: Human
Expression System: HEK293
TMEM27 Protein, Human, Recombinant (His)
TMPY-03365
Species: Human
Expression System: HEK293
LRRTM4 Protein, Mouse, Recombinant (His)
TMPY-00068
Species: Mouse
Expression System: HEK293
FLRT3 Protein, Human, Recombinant (His)
TMPY-01438
Species: Human
Expression System: HEK293
FLRT1 Protein, Human, Recombinant (His)
TMPY-02032
Species: Human
Expression System: HEK293
FLRT2 Protein, Mouse, Recombinant (His)
TMPY-03578
Species: Mouse
Expression System: HEK293
Kremen-1 Protein, Human, Recombinant (His)
TMPY-04144
Species: Human
Expression System: HEK293
TMED9 Protein, Human, Recombinant (His)
TMPY-00148
Species: Human
Expression System: HEK293
TMIGD1 Protein, Human, Recombinant (His)
TMPY-00089
Species: Human
Expression System: HEK293
TMX1 Protein, Human, Recombinant (mFc)
TMPY-05058
Species: Human
Expression System: HEK293
Collectrin Protein, Mouse, Recombinant (His & Myc & SUMO)
TMPH-02595
Species: Mouse
Expression System: E. coli
TMED1 Protein, Mouse, Recombinant (hFc)
TMPY-04861
Species: Mouse
Expression System: HEK293
Fragilis/IFITM3 Protein, Human, Recombinant (mFc)
TMPY-02841
Species: Human
Expression System: HEK293
HATL5 Protein, Human, Recombinant (His)
TMPJ-01203
Species: Human
Expression System: Human Cells
TMED9 Protein, Human, Recombinant (mFc)
TMPY-00531
Species: Human
Expression System: HEK293
TMIGD1 Protein, Human, Recombinant (mFc)
TMPY-04872
Species: Human
Expression System: HEK293
OSTM1 Protein, Human, Recombinant (His)
TMPY-01194
Species: Human
Expression System: HEK293
FLRT2 Protein, Human, Recombinant (His)
TMPY-02048
Species: Human
Expression System: HEK293
PVRIG Protein, Cynomolgus, Recombinant (His)
TMPJ-00436
Species: Cynomolgus
Expression System: Human Cells
PVRIG Protein, Cynomolgus, Recombinant (hFc)
TMPJ-00435
Species: Cynomolgus
Expression System: Human Cells
VSTM2A Protein, Human, Recombinant (His)
TMPJ-01238
Species: Human
Expression System: Human Cells
TACI Protein, Mouse, Recombinant (hFc)
TMPJ-01318
Species: Mouse
Expression System: Human Cells
TMED1 Protein, Human, Recombinant (His)
TMPY-03119
Species: Human
Expression System: HEK293
TMED1 Protein, Human, Recombinant (hFc)
TMPY-03108
Species: Human
Expression System: HEK293
Anoctamin-5/ANO5 Protein, Human, Recombinant (E. coli, His)
TMPH-00940
Species: Human
Expression System: E. coli
Anoctamin-5/ANO5 Protein, Human, Recombinant (His)
TMPH-00939
Species: Human
Expression System: HEK293
TMUB2 Protein, Human, Recombinant (His)
TMPY-03970
Species: Human
Expression System: HEK293
PVRIG Protein, Mouse, Recombinant (hFc)
TMPJ-00428
Species: Mouse
Expression System: Human Cells
CD28H/TMIGD2 Protein, Human, Recombinant (hFc)
TMPY-05440
Species: Human
Expression System: HEK293
Enteropeptidase Protein, Mouse, Recombinant (His & Myc)
TMPH-02643
Species: Mouse
Expression System: HEK293
Tomoregulin-1 Protein, Mouse, Recombinant (hFc)
TMPY-04202
Species: Mouse
Expression System: HEK293
Enteropeptidase Protein, Mouse, Recombinant (His & SUMO)
TMPH-02644
Species: Mouse
Expression System: E. coli
Cat No. Product Name
L7600 Chemokine Inhibitor Library

59 compounds
A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening;
TargetMol