417
22
78
3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8548 | Metoprine | Histone Methyltransferase , Antifolate , Histamine Receptor | |
Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity. | |||
T22782 | FGIN-1-27 | Others | |
high affinity agonist of the translocator protein | |||
T2625 | MK-0752 | Beta Amyloid , Gamma-secretase | |
MK-0752, a γ-secretase inhibitor, reduces Aβ40 production(IC50=5 nM). | |||
T15108 | DG-041 | Prostaglandin Receptor | |
DG-041 is an antagonist of high-affinity EP3 receptor (IC50s: 4.6 nM and 8.1 nM in the binding and FLIPR assay, respectively). DG-041 inhibits PGE2 facilitation of platelet aggregation and has the blood-brain barrier per... | |||
T2009 | SB-3CT | MMP | |
SB-3CT is a potent and specific gelatinase inhibitor for MMP-2(Ki=13.9 nM) and MMP-9(Ki=600 nM). | |||
T8778 | TTK21 | Epigenetic Reader Domain | |
TTK21 is an activator of CBP/p300 histone acetyltransferase activity. | |||
T3119 | JNJ-63533054 | JNJ 63533054 | GPR |
JNJ-63533054 is a potent and selective agonist of hGPR139 with an EC50 = 16 nM. | |||
T24055 | FAUC 213 | FAUC213,FAUC-213 | Dopamine Receptor |
FAUC 213 is a selective full antagonist of the dopamine D4 receptor. | |||
T1993 | J-147 | J147 | Epigenetic Reader Domain , Dopamine Receptor , Monoamine Oxidase |
J-147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate... | |||
T9687 | MAGL-IN-4 | His121 ARG57 | Lipase |
MAGL-IN-4 (His121 ARG57) is one of the monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases. | |||
T1065 | Baclofen | Lioresal | GABA Receptor |
Baclofen (Lioresal) is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen acts as a gamma-aminobutyric acid (GABA) agonist sp... | |||
T0082 | Domperidone | R33812 | Dopamine Receptor |
Domperidone (R33812)(Motilium) is a dopamine blocker and an antidopaminergic reagent. It blocks the action of. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger z... | |||
T12877L | Seltorexant | JNJ-42847922 | OX Receptor |
Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain. Seltorexant is a high-affinity and selective orexin-2 receptor antagonist (pKi: 8.0 and 8.1 for human a... | |||
T21935L | AMN082 free base | AMN082 | GluR |
AMN082 free base is a metabotropic glutamate receptor 7 allosteric agonist. | |||
T2316 | Omarigliptin | MK-3102 | Proteasome , DPP-4 |
Omarigliptin (MK-3102) has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Chronic Renal Insufficiency. | |||
T8526 | Metformin | 1,1-Dimethylbiguanide | Mitophagy , AMPK , Autophagy |
Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability. Metformin may improve glycemic control by increasing insulin sensitivity and decreasing intestinal glucose uptake, and is comm... | |||
T11861 | LM11A-31 dihydrochloride | Others | |
LM11A-31 dihydrochloride is a water-soluble, non-peptide with high blood-brain barrier permeability.LM11A-31 dihydrochloride, a p75NTR (neurotrophin receptor p75) Ligand, is a potent proNGF (nerve growth factor) antagoni... | |||
T2684 | JNJ-1661010 | JNJ1661010,Takeda-25,JNJ 1661010 | FAAH |
JNJ-1661010 (Takeda-25) is an effective and specific FAAH inhibitor (IC50: 10/ 12 nM for rat/human), shows >100-fold selectivity for FAAH-1 than FAAH-2. | |||
T28482 | Firibastat | QGC 001,QGC-001,RB-150,RB150,QGC001,RB 150 | Aminopeptidase |
Firibastat (RB150) is a glutamyl aminopeptidase antagonist and an orally active brain penetrating prodrug of EC33. It is a first-in-class brain aminopeptidase A (APA) inhibitor with a Ki of 200 nM. Firibastat selectively... | |||
T22323 | Enoxaparin sodium | Thrombin | |
Enoxaparin sodium is a low-molecular-weight heparin (LMWH) that has recently been approved by the US FDA for use in patients with medically managed ST-segment myocardial infarction (STEMI), or STEMI with subsequent percu... | |||
T12492 | Pivagabine | CXB-722 | GABA Receptor |
Pivagabine (CXB-722), a hydrophobic 4-aminobutyric acid derivative, exhibits neuromodulatory activity and successfully penetrates the blood-brain barrier in rats. It counteracts the impact of foot shock on GABAA receptor... | |||
T23394 | SR 57227A | SR 57227 hydrochloride | 5-HT Receptor |
SR 57227A (SR 57227 hydrochloride) is a potent, orally active and selective 5-HT3 receptor agonist. It with ability to cross the blood brain barrier. It has affinities (IC50) varying between 2.8 and 250 nM for 5-HT3 rece... | |||
T2141 | Mecamylamine hydrochloride | Inversine,Mevasin | AChR |
Mecamylamine hydrochloride (Mevasin) is a nicotinic antagonist, used as a ganglionic blocker in hypertension. | |||
T21422 | Methylnaltrexone bromide | Relistor,MOA-728,MOA 728,Methylnaltrexone,MOA728 | Opioid Receptor |
Methylnaltrexone bromide (MOA-728) is one of the newer agents of peripherally-acting μ-opioid antagonists. Methylnaltrexone bromide acts to reverse some of the side effects of opioid drugs such as constipation without af... | |||
T8630 | Baclofen hydrochloride | 4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride | GABA Receptor |
Baclofen hydrochloride (4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride) is a GAMMA-AMINOBUTYRIC ACID derivative that is a specific GABA-B RECEPTORS agonist. It is used in the treatment of MUSCLE SPASTICITY, espe... | |||
T13664 | DSP-4 hydrochloride | Neurotoxin DSP 4 (hydrochloride) | Others |
DSP-4 hydrochloride (Neurotoxin DSP 4 (hydrochloride)) (Neurotoxin DSP 4 hydrochloride) can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus... | |||
T20570 | Labetalol | Apo-Labetalol,Albetol,Trandate,Dilevalol,Normodyne | Adrenergic Receptor |
Labetalol (Apo-Labetalol) is a mixed alpha/beta-adrenergic antagonist.It is used to treat high blood pressure. It can be given by mouth for long term hypertension management or intravenously in severe hypertensive situat... | |||
T6438 | Cefoselis Sulfate | FK 037 Sulfate,FK-037 | Antibacterial , Antibiotic |
Cefoselis Sulfate is a widely used beta-lactam antibiotic. | |||
T7601L | Carbetocin acetate | Carbetocin acetate(37025-55-1 free base) | Oxytocin Receptor |
Carbetocin acetate is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth. | |||
T11571 | HLY78 | 4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine | Wnt/beta-catenin |
HLY78 (4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine) targets the DIX domain of Axin, is an activator of the Wnt/β-catenin signaling pathway and can enhance Axin-LRP6 binding to promote Wnt signaling. | |||
T0740 | Metformin hydrochloride | Metformin HCl,1, 1-Dimethylbiguanide hydrochloride,1,1-Dimethylbiguanide hydrochloride | Mitophagy , AMPK , Autophagy |
Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) , a widely used anti-diabetic drug, has a potential function as an anti-Y medicine. It inhibits the proliferation of a variety of Y cells including colon, pro... | |||
T0499 | Oxybenzone | KAHSCREEN BZ-3,Benzophenone 3,Eusolex 4360,Escalol 567 | Apoptosis , Retinoid Receptor , Autophagy |
Oxybenzone (Eusolex 4360) is an organic compound used in sunscreens. It is a derivative of benzophenone. | |||
T1667 | Tandutinib | MLN518,CT53518,NSC726292 | Apoptosis , FLT , CSF-1R , PDGFR , Src , c-Kit |
Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versu... | |||
T0825 | Ebselen | SPI-1005,PZ-51,CCG-39161 | Phosphatase , Virus Protease , Calcium Channel , COX , HIV Protease |
Ebselen (CCG-39161) is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced b... | |||
T7601 | Carbetocin | Oxytocin Receptor | |
Carbetocin is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth. | |||
T21935 | AMN082 | AMN 082 dihydrochloride | GluR |
AMN082 (AMN 082 dihydrochloride) is a selective metabotropic glutamate mGlu7 receptor agonist reported to exhibit antidepressant activity. | |||
TQ0238 | Lanabecestat | LY3314814,AZD3293 | BACE |
Lanabecestat (AZD3293) is a highly permeable, orally active and blood-brain barrier penetrating BACE1 inhibitor (Ki: 0.4 nM). | |||
T65232 | HEDTA | N-(2-Hydroxyethyl)ethylenediaminetriacetic acid | Others |
HEDTA is a chelating agent often used in combination with citric acid to study blood disorders and blood stress in the brain. | |||
T12017 | Methyllycaconitine citrate | MLA | AChR |
Methyllycaconitine citrate (MLA) is an α7 neuronal nicotinic acetylcholine receptor (α7nAChR) antagonist that crosses the blood-brain barrier. | |||
T6845 | GNE-317 | GNE317 | PI3K , mTOR |
GNE-317, a PI3K/mTOR inhibitor, can pass through the blood-brain barrier (BBB). | |||
TQ0026 | MDR-1339 | DWK-1339 | Beta Amyloid , Gamma-secretase |
MDR-1339 (DWK-1339) is an orally active and blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation. | |||
T17211 | Vafidemstat | ORY-2001 | Histone Demethylase , MAO |
Vafidemstat (ORY-2001) is a selective, orally active lysyl-histone demethylase (LSD1)/MAO-B inhibitor that crosses the blood-brain barrier for the study of neurological diseases. | |||
T26559 | ACT-462206 | OX Receptor | |
ACT-462206 is an orally available Orexin 1/Orexin 2 receptor antagonist that crosses the blood-brain barrier.ACT-462206 is highly potent and can be used in studies of sleep and anxiety. | |||
T1612 | Neostigmine methyl sulfate | Normastigmin,Hodostin,Syntostigmin | AChR , AChE |
Neostigmine methyl sulfate (Syntostigmin) is a reversible inhibitor of acetylcholinesterase, can not cross the blood-brain barrier, used in the treatment of myasthenia gravis. | |||
T5518 | N-acetylcysteine amide | Reactive Oxygen Species , ROS | |
N-Acetylcysteine amide is a thiol antioxidant and neuroprotective agent that can permeate cell membranes and the blood-brain barrier. | |||
T2708 | SL327 | SL 327,SL-327 | MEK , DNA/RNA Synthesis |
SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/0.22 μM; able to transport through the blood-brain barrier. | |||
T11949 | Masupirdine mesylate | SUVN-502 mesylate,SVN-502 mesylate | 5-HT Receptor |
Masupirdine mesylate (SUVN-502 mesylate) is a selective 5-HT6 receptor antagonist that crosses the blood-brain barrier.Masupirdine mesylate is used in the study of neurological disorders such as Alzheimer's disease and d... | |||
T33467 | MOMIPP | PI3K | |
MOMIPP is a PIKfyve inhibitor and a macropinocytosis inducer. MOMIPP readily penetrates the blood-brain barrier and is moderately effective in suppressing progression of intracerebral glioblastoma xenografts[1][2]. | |||
T35559 | SAG 21k | Hedgehog/Smoothened | |
SAG 21k is an orally bioactive and potent Hedgehog signaling activator that crosses the blood-brain barrier for the study of cartilage regeneration. | |||
T10855 | CO23 | Thyroid hormone receptor(THR) | |
CO23 is a blood-brain barrier penetrant and selective TRα agonist and can be used in studies about the regulation of growth and development. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0130 | Physostigmine Salicylate | AChR , AChE | |
Physostigmine, a parasympathomimetic alkaloid, is a reversible cholinesterase inhibitor. It extracts from the Calabar bean. | |||
T0795 | Rutin | Quercetin 3-O-rutinoside,Rutoside | Beta Amyloid , Prostaglandin Receptor , Autophagy |
Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties. | |||
T0848 | L-DOPA | Levodopa,3,4-Dihydroxyphenylalanine | Dopamine Receptor , Endogenous Metabolite |
L-DOPA (Levodopa) is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and can cross the blood-brain barrier. When in the brai... | |||
T22417 | Rutin hydrate | Rutoside,Sophorin,Quercetin-3-O-rutinoside | Beta Amyloid , Others , Autophagy |
Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit. | |||
T6S0444 | Salvianolic acid A | Dan Phenolic Acid A | MMP |
Salvianolic acid A (Dan Phenolic Acid A) could protect the blood brain barrier through inhibition of matrix metallopeptidase 9 (MMP-9) and anti-inflammation. | |||
T4917 | Dehydroascorbic acid | (L)-Dehydroascorbic acid | Endogenous Metabolite |
L-Dehydro Ascorbic Acid is the reversibly oxidized form of ascorbic acid;Dehydroascorbic acid ((L)-Dehydroascorbic acid), a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experi... | |||
T6S0119 | Dauricine | Apoptosis , Others , NF-κB | |
1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important ro... | |||
T4710 | 3-Methoxytyramine hydrochloride | 3-O-methyl Dopamine hydrochloride,3-O-methyl Dopamine hydrochloride) | Others , Endogenous Metabolite , Drug Metabolite |
3-Methoxytyramine hydrochloride (3-O-methyl Dopamine hydrochloride) is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1). 3-methoxytyramine can be found primarily in human br... | |||
T13979 | (S)-3-Hydroxybutanoic acid | L-β-Hydroxybutyric acid,(S)-β-Hydroxybutanoic acid,L-(+)-3-Hydroxybutyric acid | Endogenous Metabolite |
(S)-3-Hydroxybutanoic acid (L-(+)-3-Hydroxybutyric acid) is a normal human metabolite that has been found elevated in geriatric patients remitting from depression. (S)-3-Hydroxybutanoic acid is synthesized in the liver f... | |||
T0883 | Tramiprosate | Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed | Beta Amyloid , GABA Receptor |
Tramiprosate (Alzhemed) is an orally active, blood-brain-barrier-crossing, naturally occurring amino acid found in a variety of red seaweeds that binds soluble Aβ and maintains it in a non-protofibrillar form.It is a GAB... | |||
T4947 | 3-Hydroxybutyric acid | Butanoic acid | Endogenous Metabolite |
3-Hydroxybutyric acid (Butanoic acid) (or beta-hydroxybutyrate) is a ketone body. Like the other ketone bodies (acetoacetate and acetone), levels of 3-hydroxybutyrate in blood and urine are raised in ketosis. In humans, ... | |||
T5S1632 | Barlerin | 8-O-Acetylshanzhiside methyl ester,ND01 | VEGFR , TNF , NF-κB , Akt , Caspase |
Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and its protective effect on oxygen-glucose deprivation-induced injury might be due to the suppression of intracellular Ca2+ e... | |||
T5232 | 3-Methyl-2-oxobutanoic acid | 2-Oxoisovaleric acid,alpha-Ketoisovaleric acid | Others , Endogenous Metabolite |
3-Methyl-2-oxobutanoic acid (2-Oxoisovaleric acid) is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. 3-Methyl-2-oxobutanoic acid is a neurotoxin, an acidogen, and a metabo... | |||
T4439 | Sn-Glycero-3-phosphocholine | Choline Alfoscerate,Glycerophosphocholine,Glycerophosphorylcholine,Alpha-GPC,Choline glycerophosphate,L-α-GPC | Endogenous Metabolite , AChE |
sn-Glycero-3-phosphocholine (Choline glycerophosphate) is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have a potential for the treatment o... | |||
T3893 | Forsythoside B | TNF , NF-κB | |
Forsythoside B binds to LPS and reduces the biological activity of serum LPS, and inhibits NF-κB activation. Forsythoside B inhibits the inflammatory response and has antioxidant properties. Potent neuroprotective effect... | |||
T13493 | 3-Acetyldeoxynivalenol | Others | |
3-Acetyldeoxynivalenol is a trichothecene mycotoxin deoxynivalenol acetylated derivative and a blood-brain barrier (BBB) permeable mycotoxin. | |||
T14114 | Acivicin | AT-125,U-42126 | Others |
Acivicin (AT-125) is a γ-glutamyl transpeptidase (GGT) inhibitor derived from the Streptomyces sviceus natural product. It possesses anti-cancer and anti-parasitic properties and can effectively cross the blood-brain bar... | |||
T13680 | Enniatin B1 | ERK | |
Enniatin B1, a Fusarium mycotoxin, crosses the blood-brain barrier, decreases the activation of ERK (p44/p42), and inhibits moderately TNF-α-induced NF-κB activation. Furthermore, it inhibits acyl-CoA: cholesterol acyltr... | |||
T61171 | Cyclo(his-pro) TFA | ||
Cyclo(his-pro) TFA, an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone, has shown inhibitory effects on NF-κB nuclear accumulation. Additionally, it possesses the ability to cross the... | |||
T77207 | Acivicin hydrochloride | ||
Acivicin hydrochloride (AT-125 hydrochloride), derived from Streptomyces sviceus, functions as a γ-glutamyl transpeptidase (GGT) inhibitor. This compound possesses the ability to cross the blood-brain barrier and demonst... | |||
T75571 | Withaphysalin D | ||
Withaphysalin D, isolated from water lilies, is a selective antagonist for the N-methyl-D-aspartate receptor (NMDAR) containing GluN2B with neuroprotective properties. This compound is capable of crossing the blood-brain... | |||
TN3364 | Agrimonolide | Apoptosis , Dehydrogenase , p38 MAPK , ROS , JAK | |
Agrimonolide, a compound derived from isocoumarins and found mainly in the herb Agrimonia pilosa Ledeb, has significant biological activity. agrimonolide exerts anti-inflammatory effects by inhibiting lipopolysaccharide ... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01776 | Carboxylesterase 2/CES2 Protein, Human, Recombinant (His) | Human | HEK293 |
Carboxylesterase 2 (CES2) is a member of the carboxylesterase family and belongs to the multigene family. Carboxylesterase 2 is responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and... | |||
TMPY-04683 | CD47 Protein, Human, Recombinant | Human | HEK293 |
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem... | |||
TMPY-03093 | CD47 Protein, Rat, Recombinant (His) | Rat | HEK293 |
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem... | |||
TMPY-05191 | CD47 Protein, Human, Recombinant, Biotinylated | Human | HEK293 |
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem... | |||
TMPY-05276 | CD47 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 |
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem... | |||
TMPY-04810 | CD47 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem... | |||
TMPY-05343 | CD47 Protein, Cynomolgus, Rhesus, Recombinant (His) | Cynomolgus,Rhesus | HEK293 |
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem... | |||
TMPY-04935 | CD47 Protein, Human, Recombinant (aa 1-139, His) | Human | HEK293 |
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem... | |||
TMPY-00637 | FLT1 Protein, Human, Recombinant (aa 1-328, His) | Human | HEK293 |
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a si... | |||
TMPY-01938 | CD98 Protein, Human, Recombinant (His) | Human | HEK293 |
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr... | |||
TMPY-02358 | CD98 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr... | |||
TMPJ-00412 | VEGFR1/FLT-1 Protein, Human, Recombinant (hFc) | Human | Human Cells |
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 ... | |||
TMPY-01725 | Leptin Receptor Protein, Human, Recombinant (His) | Human | HEK293 |
Leptin Receptor or CD295 belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-spe... | |||
TMPH-02122 | SLC2A1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most imp... | |||
TMPH-03756 | Wint7b Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli |
Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal fusion of the chorion and the allantois during placenta d... | |||
TMPH-02980 | Aquaporin-4/AQP4 Protein, Mouse, Recombinant (His) | Mouse | Yeast |
Forms a water-specific channel. Plays an important role in brain water homeostasis and in glymphatic solute transport. Required for a normal rate of water exchange across the blood brain interface. Required for normal le... | |||
TMPH-02861 | Wnt7b Protein, Mouse, Recombinant (His & Myc & SUMO) | Mouse | E. coli |
Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal fusion of the chorion and the allantois during placenta d... | |||
TMPK-00695 | N Cadherin Protein, Human, Recombinant (hFc) | Human | HEK293 |
Neural (N)-cadherin is a calcium-dependent single-chain transmembrane glycoprotein that mediates homotypic and heterotypic cell-cell adhesion. As an important member of the cadherin family, N-cadherin plays an important ... | |||
TMPJ-01439 | Asprosin Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Asprosin is a protein hormone that is produced by white adipose tissue in mammals (and potentially by other tissues), which is then transported to the liver and stimulates it to release glucose into the blood stream. In ... | |||
TMPH-03250 | NPR3 Protein, Rat, Recombinant (His & SUMO) | Rat | E. coli |
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance... | |||
TMPJ-01451 | Asprosin Protein, Human, Recombinant (His) | Human | Human Cells |
Asprosin is a protein hormone that is produced by white adipose tissue in mammals (and potentially by other tissues), which is then transported to the liver and stimulates it to release glucose into the blood stream. In ... | |||
TMPJ-01282 | Serpin B12 Protein, Human, Recombinant (His) | Human | Human Cells |
Serpin B12 is a member of the serpin family. Serpins are the largest and most diverse family of serine protease inhibitors. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular f... | |||
TMPJ-01398 | ITM2B Protein, Human, Recombinant (His) | Human | Human Cells |
Integral Membrane Protein 2B (ITM2B) is expressed in the Golgi and on the cell surface. ITM2B forms homodimer through disulfide-linked interaction with SPPL2A, SPPL2B and APP. ITM2B is expressed in brain and the other ti... | |||
TMPY-01718 | Serpin B12 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, infl... | |||
TMPJ-00114 | EFNA3 Protein, Mouse, Recombinant (hFc) | Mouse | Human Cells |
Ephrins-A3 belongs the Ephrins ligand family which involved in a variety of biological processes, especially in the nervous system and in erythropoiesis. It is shown that Ephrin-A3 is expressed in brain, skeletal muscle,... | |||
TMPY-04327 | VEGFB Protein, Human, Recombinant (hFc) | Human | HEK293 |
Vascular endothelial growth factor-B (VEGF-B) is closely related to VEGF-A, an effector of blood vessel growth during development and disease and a strong candidate for angiogenic therapies. In detail, VEGFB can positive... | |||
TMPY-01922 | PDE9A Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, also known as PDE9A, is a member of the cyclic nucleotide phosphodiesterase family and PDE9 subfamily. PDE9A is expressed in all tissues examined (testis, br... | |||
TMPY-01921 | PDE9A Protein, Human, Recombinant (His) | Human | E. coli |
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, also known as PDE9A, is a member of the cyclic nucleotide phosphodiesterase family and PDE9 subfamily. PDE9A is expressed in all tissues examined (testis, br... | |||
TMPJ-00243 | Serpin B6 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Serpin B6 belongs to the serpin family. Serpin B6 localizes to the cytoplasm. Serpin B6 is expressed in many tissues, abundantly by mast cells in different tissues and mastocytoma lesions. Serpin B6 may be involved in th... | |||
TMPJ-00551 | Siglec-9 Protein,Human, Recombinant(aa 18-348, His) | Human | Human Cells |
Sialic acid-binding Ig-like lectin 9(Siglec 9) is expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils), and found in liver, fetal liver, bone marrow, placenta, spleen and in lower leve... | |||
TMPK-01048 | Aggrecan Protein, Human, Recombinant (His) | Human | HEK293 |
Aggrecan is a large proteoglycan that forms giant hydrated aggregates with hyaluronan in the extracellular matrix (ECM). The extraordinary resistance of these aggregates to compression explains their abundance in articul... | |||
TMPJ-00550 | Siglec-9 Protein, Human, Recombinant (hFc) | Human | Human Cells |
Sialic acid-binding Ig-like lectin 9(Siglec 9) is expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils), and found in liver, fetal liver, bone marrow, placenta, spleen and in lower leve... | |||
TMPJ-01061 | Nucleobindin-2 Protein, Human, Recombinant | Human | E. coli |
Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2). Nesfatin-1 is a neuropeptide produced in the hypothalamus of mammals. It participates in the regulat... | |||
TMPJ-00763 | ANG Protein, Human, Recombinant | Human | E. coli |
Angiogenin belongs to the pancreatic ribonuclease family. Angiogenin is primarily expressed in the liver. It may act as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular t... | |||
TMPY-03340 | MAP1LC3A Protein, Human, Recombinant (His) | Human | E. coli |
LC3A, also known as MAP1LC3A, is one of the light chain subunits that function together with both MAP1A and/or MAP1B. MAP1A and MAP1B are microtubule-associated proteins that mediate the physical interactions between mic... | |||
TMPY-03658 | ETHE1 Protein, Human, Recombinant (His) | Human | E. coli |
ETHE1, also known as HSCO, is a sulfur dioxygenase that localizes within the mitochondrial matrix. ETHE1 probably plays an important role in metabolic homeostasis in mitochondria. It may also function as a nuclear-cytopl... | |||
TMPJ-00990 | S100B Protein, Mouse, Recombinant (His) | Mouse | E. coli |
S100-B, is an acidic protein with a molecular weight of 21 kDa belonging to the S100 family. S100-B contains two EF-hand-type calcium-binding motifs separated by a hinge region with a hydrophobic cleft. S100-B plays an i... | |||
TMPY-03109 | PHYH Protein, Human, Recombinant | Human | E. coli |
PHYH belongs to the family of iron(II)-dependent oxygenases, which typically incorporate one atom of dioxygen into the substrate and one atom into the succinate carboxylate group. PHYH is expressed in liver, kidney, and ... | |||
TMPY-00967 | Carbonic Anhydrase 14 Protein, Human, Recombinant (His) | Human | HEK293 |
The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bi... | |||
TMPY-00691 | Carbonic Anhydrase 14 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bi... | |||
TMPY-01690 | Carboxylesterase 2/CES2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Carboxylesterase 2 (CES2) is a member of the carboxylesterase family and belongs to the multigene family. Carboxylesterase 2 is responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and... | |||
TMPH-01604 | SLC7A5 Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli |
The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptop... | |||
TMPJ-00977 | LEPR Protein, Mouse, Recombinant (mFc) | Mouse | Human Cells |
The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta... | |||
TMPJ-00975 | LEPR Protein, Mouse, Recombinant (hFc) | Mouse | Human Cells |
The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta... | |||
TMPJ-00976 | LEPR Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta... | |||
TMPJ-00411 | LEPR Protein, Human, Recombinant (hFc) | Human | Human Cells |
The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta... | |||
TMPJ-01000 | CCL9 Protein, Mouse, Recombinant | Mouse | E. coli |
C-C motif chemokine 9(CCL9) is an 11 kDa, secreted, monomeric polypeptide that belongs to the beta (or CC) intercrine family of chemokines. It is expressed mainly in the liver, lung, and the thymus, although some express... | |||
TMPH-01342 | Filamin-A Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplas... | |||
TMPY-02950 | WWP2 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
WWP2 contains 1 C2 domain, 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain and 4 WW domains. It is an E3 ubiquitin-protein ligase that accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thio... | |||
TMPH-02855 | PML Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Functions via its association with PML-nuclear bodies (PML-NBs) in a wide range of important cellular processes, including tumor suppression, transcriptional regulation, apoptosis, senescence, DNA damage response, and vi... | |||
------------------------ More ------------------------ |
Cat No. | Product Name | ||
---|---|---|---|
L5900 | CNS-Penetrant Compound Library | 516 compounds | |
A unique collection of 516 CNS-Penetrant compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L7110 | Anti-Hypertension Compound Library | 719 compounds | |
719 hypertension-related small molecules for high-throughput and high-content screening. | |||
L6750 | PBCRBS Traditional Chinese Medicine Compound Library | 588 compounds | |
A unique collection of 588 compounds derived from traditional Chinese medicines (TCMs) for promoting blood circulation and removing blood stasis. |