b 02

RAD51 Inhibitor B02 (B02) (B02) is an inhibitor of human RAD51 with an IC50 of 27.4 μM.

Dynamin-related GTPase DRP1 partial inhibitor (IC50 = 1.2 μM). Selective for DRP1 over other dynamin-related GTPases, OPA1 and DYN1. Increases mitochondrial DNA levels in mfn1- knockout MEFs deficient in mitochondrial fusion. Mallat et al (2018) Discovery and characterization of selective small molecule inhibitors of the mammalian mitochondrial division dynamin, DRP1. Biochem.Biophys.Res.Commun. 499 556 PMID:29601815

EAPB 02303 is a microtubule-disrupting agent and inhibitor that induces mitosis arrest and spindle assembly impairment, leading to apoptosis (programed cell death) and demonstrating antitumor activity. Furthermore, it exhibits potent synergy with Paclitaxel at lower concentrations [1].

2H,3H-thieno[3,4-b][1,4]dioxine-5-carbonitrile, with CAS No. 859851-02-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2H,3H-thieno[3,4-b][1,4]dioxine-5-carbonitrile provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Austalide B is a useful organic compound for research related to life sciences. The catalog number is T124176 and the CAS number is 81543-02-4.

Psilostachyin B is a useful organic compound for research related to life sciences. The catalog number is T124366 and the CAS number is 6995-02-4.

Parvisoflavone B is a useful organic compound for research related to life sciences. The catalog number is T124761 and the CAS number is 50277-02-6.

Nocturnoside B is a useful organic compound for research related to life sciences. The catalog number is T125635 and the CAS number is 166604-02-0.

MNN-02-155 is a bivalent molecular glue that can simultaneously interact with both p300/CBP and BCL6. It effectively induces the activation of BCL6-targeted reporter genes and promotes cell death. This compound is used in the research of diffuse large B-cell lymphoma (DLBCL).

Karavilagenin B is a natural product for research related to life sciences. The catalog number is TN6308 and the CAS number is 912329-02-3.

IRL-1038 TFA is a selective and potent endothelin B (ETB) receptor antagonist that inhibits endothelin-induced endothelium-dependent relaxation and can be used in the study of cardiovascular disease.