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Anti-Adiponectin Antibody (6Q759)
🥰Excellent
Catalog No. TMAB-02342
Antibody Type: Mouse Monoclonal
Application: IHC-P,IHC-Fr,IF
Reactivity: Human
Anti-Adiponectin Antibody (6Q759)
Anti-Adiponectin Antibody (6Q759)
🥰Excellent
Catalog No. TMAB-02342
Antibody Type: Mouse Monoclonal
Application: IHC-P,IHC-Fr,IF
Reactivity: Human
Application: IHC-P,IHC-Fr,IF
Reactivity: Human
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Adiponectin Antibody (6Q759) is a Mouse antibody targeting Adiponectin. Anti-Adiponectin Antibody (6Q759) can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Clone | 6Q759 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Synthesized exclusively by adipocytes and secreted into plasma. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Adiponectin: A protein hormone produced and secreted exclusively by adipocytes (fat cells) that regulates the metabolism of lipids and glucose. Adiponectin influences the body's response to insulin. Adiponectin also has antiinflammatory effects on the cells lining the walls of blood vessels. High blood levels of adiponectin are associated with a reduced risk of heart attack. Low levels of adiponectin are found in people who are obese (and who are at increased risk of a heart attack). Adipocytes produce and secrete a number of proteins, including leptin, adipsin, properdin, and tumor necrosis factor (TNF). An adipose tissue-specific factor was isolated and termed APM1 (AdiPose Most abundant gene transcript 1). The protein product of APM1 is adiponectin. The APM1 gene maps to chromosome 3q27. |
| Immunogen | KLH conjugated synthetic peptide: human Adiponectin |
| Antigen Species | Human |
| Gene Name | ADIPOQ |
| Gene ID | |
| Protein Name | Adiponectin |
| Uniprot ID | |
| Function | Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. |
| Molecular Weight | Theoretical: 25 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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