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Search Results for " sars "

Targets

424

Compounds

489

Recombinant Proteins

3

Libraries

Cat No. Product Name
T77510 SARS-CoV-2-IN-46 SARS-CoV
SARS-CoV-2-IN-46 is a SARS-CoV-2 inhibitor.
T77516 SARS-CoV-2-IN-39 Antiviral , SARS-CoV
SARS-CoV-2-IN-39 is a SARS-CoV-2 inhibitor with an EC50 of 1 μM. SARS-CoV-2-IN-39 has antiviral activity and inhibits SA...
T77652 SARS-CoV-2 3CLpro-IN-20 Antiviral , SARS-CoV
SARS-CoV-2 3CLpro-IN-20 is a covalent SARS-CoV-2 3CLpro inhibitor (IC50s: 0.43 μM,).SARS-CoV-2 3CLpro-IN-20 has potentia...
T60538 SARS-CoV-2-IN-14 3',5-Dichlorosalicylanilide SARS-CoV
SARS-CoV-2-IN-14 is a potent and oral inhibitor of SARS-CoV-2 (IC50:0.39 μM), which is an analogue of niclosamide. SARS-...
T36654 Anti-SARS-CoV-2 Spike mAb (CR3022) Anti-SARS-CoV-2 Spike mAb (CR3022)
Anti-SARS-CoV-2 Spike mAb (CR3022) is a human monoclonal IgG1 antibody derived from CHO cells. It specifically targets t...
T60919 SARS-CoV-2-IN-13 SARS-CoV
SARS-CoV-2-IN-13 (compound 5) is an analogue of niclosamide. SARS-CoV-2-IN-13 is more stable than niclosamide in human p...
T79659 SARS-CoV-2 3CLpro-IN-16 SARS-CoV
SARS-CoV-2 3CLpro-IN-16 (Compound 3a) is a covalent inhibitor of SARS-CoV-2 3CLpro, exhibiting an inhibitory concentrati...
T36653 Anti-SARS-80R mAb
Anti-SARS-80R mAb (SARS-80R) is a human IgG1 monoclonal antibody that is derived from CHO cells. Its main function is to...
T40207 SARS-CoV-2-IN-7
SARS-CoV-2-IN-7 demonstrates potent inhibition of viral replication in SARS-CoV-2-infected Vero E6 cells with an IC50 va...
T38942 SARS-CoV-2-IN-9
SARS-CoV-2-IN-9 is an inhibitor binding to subsites S1 and S2 in SARS-CoV-2 main protease.
T40340 SARS-CoV-2-IN-10
SARS-CoV-2-IN-10 is a powerful and non-toxic inhibitor of SARS-CoV-2 3CL protease, with IC50 and EC50 values of 0.13 nM ...
T40341 SARS-CoV-2-IN-11
SARS-CoV-2-IN-11 is a highly potent and non-toxic inhibitor of the 3C-like protease (3CLpro) of SARS-CoV-2, demonstratin...
T12838 SARS-CoV-IN-2 Others
SARS-CoV-IN-2 is an effective SARS-CoV replication inhibitor
T12839 SARS-CoV-IN-3 Others
SARS-CoV-IN-3 is an effective SARS-CoV replication inhibitor.
T12837 SARS-CoV-IN-1 Others
SARS-CoV-IN-1 is an effective SARS-CoV replication inhibitor(EC50 of 4.9 μM in Vero cells).
T12836 SARS-CoV-2-IN-1 Others
SARS-CoV-2-IN-1 is a potent inhibitor of Mpro(SARS-CoV-2 Mpro, SARS-CoV Mpro and MERS-CoV Mpro with IC50s of 0.67, 0.90 ...
T37174 SARS-CoV MPro-IN-1
MProinhibitor 11b is an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro; I...
TN3651 Cichoriin Others
Cichoriin is a photosensitive compound, it could be used as herbal photosensitizing agent in treating benign breast tumo...
T9458 PF-00835231 SARS-CoV
PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and S...
T3S1447 Arteannuin B SARS-CoV , Ferroptosis
1. Arteannuin B has potent antimalarial activity.
1 2 3 4 5 ... 22
Cat No. Product Name Species Source
TMPY-02870 SARS-CoV Nucleocapsid Protein (His) SARS Baculovirus-Insect Cells
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. The coronavirus N protein is required for coronavirus RNA synthesis and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is the most abundant protein ...
TMPY-05702 SARS-CoV Spike/S1 Protein (mFc) SARS HEK293
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPY-04177 SARS-CoV Spike/RBD Protein (rFc) SARS Baculovirus-Insect Cells
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPY-05701 SARS-CoV Spike/RBD Protein (mFc) SARS HEK293
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPY-03224 SARS-CoV Spike/RBD Protein (His) SARS Baculovirus-Insect Cells
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPY-03988 SARS-CoV Spike/S1 Protein (His) SARS Baculovirus-Insect Cells
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPY-05699 SARS-CoV Spike/S1 Protein (His), Biotinylated SARS Baculovirus-Insect Cells
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPY-05817 SARS-CoV Spike/RBD Protein (His), Biotinylated SARS Baculovirus-Insect Cells
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPY-06372 SARS-CoV Spike RBD Protein (mFc), Biotinylated SARS HEK293
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPY-05722 SARS-CoV Spike S2-His Recombinant Protein SARS Baculovirus-Insect Cells
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPJ-01426 NSP2 Protein, SARS-CoV-2, Recombinant (His) SARS-CoV-2 E. coli
The positive-stranded RNA genome of the coronaviruses is translated from ORF1 to yield polyproteins that are proteolytically processed into intermediate and mature nonstructural proteins (nsps). SARS-CoV 2 polyproteins incorporate 16 protein domains (nsps). The putative non-structural protein 2 (nsp2) of SARS-CoV plays an important role in viral transcription and replication, and is an attractive target for anti-SARS drug development.
TMPY-06204 SARS-CoV (Isolate Tor2) Spike RBD Protein (His & AVI), Biotinylated SARS HEK293
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPJ-01425 NSP1 Protein, SARS-CoV-2, Recombinant (His) SARS-CoV-2 E. coli
The Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) is an enveloped, positive-stranded RNA viruses that can cause a severe respiratory disease. Its genome consists of a ∼30 kb linear, non-segmented, capped, polycistronic, polyadenylated RNA molecule, the first two-third of which is directly translated into two large polyproteins. These two polypeptides are processed into 16 non-structural proteins (nsps), forming the replicase complex, which is active in the cytoplasm in close associa...
TMPJ-01450 Helicase Protein, SARS-CoV-2, Recombinant (His & MBP) SARS-CoV-2 E. coli
The non—structural protein 13 (nsp13) of SARS—CoV 2 is a helicase that separates double—stranded RNA or DNA with a 5'—3' polarity, using the energy of nucleotide hydrolysis. A basic biochemical characterization of nsp13 demonstrated that it can unwind both doublestranded DNA and RNA in a 5’-3’ direction, and it can hydrolyze all deoxyribonucleotide and ribonucleotide triphosphates. Helicases are motor proteins that utilize the energy derived from nucleotide hydrolysisto unwind double-stranded nu...
TMPJ-01427 NSP7 Protein, SARS-CoV-2, Recombinant (His) SARS-CoV-2 E. coli
The ∼30kb positive-stranded RNA genome of coronaviruses encodes a replication/transcription machinery that is unusually complex and composed of 16 nonstructural proteins (nsps). The four proteins nsp7 to nsp10, which are conserved among all CoVs but have no functional homologs outside of the Coronaviridae, are translated as part of the viral polyproteins pp1a and pp1ab, and the mature proteins are released by the action of the SARS-CoV protease nsp5. Hexadecamer of nsp7 and nsp8 may possess dsRN...
TMPJ-01428 NSP8 Protein, SARS-CoV-2, Recombinant (His) SARS-CoV-2 E. coli
Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis. It forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers.Nsp8 was shown to have RNA-dependen...
TMPY-05718 SARS-CoV Spike S1+S2 ECD-His Recombinant Protein (S577A, Isolate Tor2) SARS Baculovirus-Insect Cells
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPY-06176 SARS-CoV (Isolate Tor2) Spike S1+S2 (S577A) Protein (His), Biotinylated SARS Baculovirus-Insect Cells
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPJ-01429 Guanine-N7_meth Protein, SARS-CoV-2, Recombinant (His) SARS-CoV-2 E. coli
The nonstructural protein (nsp) 14 of SARS-CoV 2 was identified as a cap (guanine-N7)-methyltransferase (N7-MTase). Nsp14 of coronaviruses two different activities: an exoribonuclease activity acting on both ssRNA and dsRNA in a 3' to 5' direction and a N7-guanine methyltransferase activity. It may be involved in the proof-reading ability during the viral RNA replication and transcription. GTP, dGTP as well as cap analogs GpppG, GpppA and m7GpppG could be methylated by nsp14.
TMPY-06416 SARS-CoV-2 NSP8 Protein SARS-CoV-2 E. coli
NSP8 is a nonstructural protein of coronavirus. NSP8 acts as a primase in RNA synthesis. NSP8 and NSP7 are essential co-factors of NSP12 (the catalytic subunit with RNA-dependent RNA polymerase activity) that can remarkably stimulate RdRp activity. The nsp12-nsp7-nsp8 subcomplex is defined as the minimal core component for mediating coronavirus RNA synthesis.

Recombinant Proteins

SARS-CoV Nucleocapsid Protein (His)
TMPY-02870
Species: SARS
Source: Baculovirus-Insect Cells
SARS-CoV Spike/S1 Protein (mFc)
TMPY-05702
Species: SARS
Source: HEK293
SARS-CoV Spike/RBD Protein (rFc)
TMPY-04177
Species: SARS
Source: Baculovirus-Insect Cells
SARS-CoV Spike/RBD Protein (mFc)
TMPY-05701
Species: SARS
Source: HEK293
SARS-CoV Spike/RBD Protein (His)
TMPY-03224
Species: SARS
Source: Baculovirus-Insect Cells
SARS-CoV Spike/S1 Protein (His)
TMPY-03988
Species: SARS
Source: Baculovirus-Insect Cells
SARS-CoV Spike/S1 Protein (His), Biotinylated
TMPY-05699
Species: SARS
Source: Baculovirus-Insect Cells
SARS-CoV Spike/RBD Protein (His), Biotinylated
TMPY-05817
Species: SARS
Source: Baculovirus-Insect Cells
SARS-CoV Spike RBD Protein (mFc), Biotinylated
TMPY-06372
Species: SARS
Source: HEK293
SARS-CoV Spike S2-His Recombinant Protein
TMPY-05722
Species: SARS
Source: Baculovirus-Insect Cells
NSP2 Protein, SARS-CoV-2, Recombinant (His)
TMPJ-01426
Species: SARS-CoV-2
Source: E. coli
SARS-CoV (Isolate Tor2) Spike RBD Protein (His & AVI), Biotinylated
TMPY-06204
Species: SARS
Source: HEK293
NSP1 Protein, SARS-CoV-2, Recombinant (His)
TMPJ-01425
Species: SARS-CoV-2
Source: E. coli
Helicase Protein, SARS-CoV-2, Recombinant (His & MBP)
TMPJ-01450
Species: SARS-CoV-2
Source: E. coli
NSP7 Protein, SARS-CoV-2, Recombinant (His)
TMPJ-01427
Species: SARS-CoV-2
Source: E. coli
NSP8 Protein, SARS-CoV-2, Recombinant (His)
TMPJ-01428
Species: SARS-CoV-2
Source: E. coli
SARS-CoV Spike S1+S2 ECD-His Recombinant Protein (S577A, Isolate Tor2)
TMPY-05718
Species: SARS
Source: Baculovirus-Insect Cells
SARS-CoV (Isolate Tor2) Spike S1+S2 (S577A) Protein (His), Biotinylated
TMPY-06176
Species: SARS
Source: Baculovirus-Insect Cells
Guanine-N7_meth Protein, SARS-CoV-2, Recombinant (His)
TMPJ-01429
Species: SARS-CoV-2
Source: E. coli
SARS-CoV-2 NSP8 Protein
TMPY-06416
Species: SARS-CoV-2
Source: E. coli
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TargetMol