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Lenzilumab

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Catalog No. T76751Cas No. 1229575-09-0
Alias KB003, KB 003

Lenzilumab (KB 003) is a humanized granulocyte-macrophage colony-stimulating factor (GM-CSF) neutralizing antibody that directly binds to GM-CSF and prevents signaling through its receptor, and can be used to study COVID-19.

Lenzilumab

Lenzilumab

😃Good
Catalog No. T76751Alias KB003, KB 003Cas No. 1229575-09-0
Lenzilumab (KB 003) is a humanized granulocyte-macrophage colony-stimulating factor (GM-CSF) neutralizing antibody that directly binds to GM-CSF and prevents signaling through its receptor, and can be used to study COVID-19.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$183In StockIn Stock
5 mg$463In StockIn Stock
10 mg$742-In Stock
25 mg$1,120-In Stock
50 mg$1,490-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:98.9% (SDS-PAGE); 98.5% (SEC-HPLC)
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Product Introduction

Bioactivity
Description
Lenzilumab (KB 003) is a humanized granulocyte-macrophage colony-stimulating factor (GM-CSF) neutralizing antibody that directly binds to GM-CSF and prevents signaling through its receptor, and can be used to study COVID-19.
In vivo
Intraperitoneal injection of 10 mg/kg Lenzilumab once daily for 10 days improved its antitumor effect in NSG mice by inhibiting GM-CSF without impairing the cellular function of CAR-T and at the same time. [1]
SynonymsKB003, KB 003
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetCSF2/GM-CSF
Chemical Properties
Molecular Weight146.81 kDa
Cas No.1229575-09-0
ColorTransparent
AppearanceLiquid
Antibody Information
IsotypeIgG1
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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