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Lenzilumab (Synonyms: KB003, KB 003)

Catalog No. T76751 Copy Product Info
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Lenzilumab (KB 003) is a humanized granulocyte-macrophage colony-stimulating factor (GM-CSF) neutralizing antibody that directly binds to GM-CSF and prevents signaling through its receptor, and can be used to study COVID-19.

Lenzilumab

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Catalog No. T76751
Synonyms KB003, KB 003

Lenzilumab (KB 003) is a humanized granulocyte-macrophage colony-stimulating factor (GM-CSF) neutralizing antibody that directly binds to GM-CSF and prevents signaling through its receptor, and can be used to study COVID-19.

Lenzilumab
Cas No. 1229575-09-0
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$183In StockIn Stock
5 mg$463In StockIn Stock
10 mg$742-In Stock
25 mg$1,120-In Stock
50 mg$1,490-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.9% (SDS-PAGE); 98.5% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Lenzilumab (KB 003) is a humanized granulocyte-macrophage colony-stimulating factor (GM-CSF) neutralizing antibody that directly binds to GM-CSF and prevents signaling through its receptor, and can be used to study COVID-19.
In vivo
Intraperitoneal injection of 10 mg/kg Lenzilumab once daily for 10 days improved its antitumor effect in NSG mice by inhibiting GM-CSF without impairing the cellular function of CAR-T and at the same time. [1]
SynonymsKB003, KB 003
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetCSF2/GM-CSF
Chemical Properties
Molecular Weight146.81 kDa
Cas No.1229575-09-0
Antibody Information
IsotypeIgG1
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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