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Results for "

natural product

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    4754
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    TargetMol | Inhibitors_Agonists
Cepharanthine
NSC-623442
T0131481-49-2
Cepharanthine (NSC-623442) is a natural alkaloid that inhibits TNF-α-mediated NFκB stimulation, plasma membrane lipid peroxidation, and platelet aggregation, as well as cytokine production. Cepharanthine exhibits anti-inflammatory, antioxidant, and antitumor activities.
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Quercetin
Sophoretin
T2174117-39-5
Quercetin, a flavonoid natural product, is a SIRT1 activator. It is also a PI3K inhibitor, inhibiting PI3Kγ, PI3Kδ, and PI3Kβ with IC50 values of 2.4, 3.0, and 5.4 μM, respectively. Recognized as a heat shock protein inhibitor, Quercetin can significantly reduce exosome release in TII models by downregulating Hsp70 or Hsp90.
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TargetMol | Inhibitor Hot
Rotenone
Rotocide, Rotenon, Paraderil, Dactinol, Barbasco
T297083-79-4
Rotenone (Rotocide) is a natural product and a botanical insecticide. Rotenone is a mitochondrial electron transport complex I inhibitor that promotes the production of reactive oxygen species in mitochondria and induces apoptosis.
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Paclitaxel
Taxol, NSC 125973
T096833069-62-4
Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest, apoptosis, and cell autophagy.
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TargetMol | Inhibitor Hot
Capsaicin
Zostrix, Qutenza, 8-Methyl-N-vanillyl-trans-6-nonenamide, (E)-Capsaicin
T1062404-86-4
Capsaicin ((E)-Capsaicin) is a natural product extracted from Capsicum annuum, and is a TRPV1 agonist (EC50=0.29 μM). Capsaicin has antitumor, anti-inflammatory, antioxidant and neuroprotective activities.
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TargetMol | Inhibitor Hot
Cycloheximide
Naramycin A, CHX, Actidione
T122566-81-9
Cycloheximide (Naramycin A) is a natural product that reversibly inhibits translation elongation, is an antimitotic compound, and is an inhibitor of DNA and protein synthesis.
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TargetMol | Inhibitor Hot
Rapamycin
Sirolimus, NSC-2260804, AY 22989
T153753123-88-9
Rapamycin (AY 22989) is a natural product of macrolides, an mTOR inhibitor with specificity (HEK293 cells: IC50=0.1 nM). Rapamycin has immunosuppressive activity and induces autophagy.
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Resveratrol
trans-Resveratrol, SRT 501
T1558501-36-0
Resveratrol (SRT 501) is a polyphenolic natural product, a plant antitoxin with antioxidant and chemopreventive activities. Resveratrol has a wide range of targets including COX, SIRT, LOC, etc. Resveratrol induces autophagy and apoptosis.
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TargetMol | Inhibitor Hot
Forskolin
FSK, Colforsin, Coleonol
T293966575-29-9
Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM). Forskolin increases cAMP levels, activates PXR and FXR, and induces autophagy. Forskolin produces positive inotropic effects in the heart, and has platelet anticoagulant and antihypertensive effects.
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TargetMol | Inhibitor Hot
L-Lactic acid
L-(+)-Lactic acid, 2-HYDROXYPROPIONIC ACID, (S)-2-Hydroxypropanoic acid
T484579-33-4
L-Lactic acid ((S)-2-Hydroxypropanoic acid) is a natural product produced by the anaerobic glycolysis of pyruvic acid. L-Lactic acid is a sensitive indicator of tissue hypoxia and can be used as a hemodynamic indicator in critically ill patients.
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TargetMol | Inhibitor Hot
Salvianolic acid A
Dan Phenolic Acid A
T6S044496574-01-5
Salvianolic acid A (Dan Phenolic Acid A) is a natural product and an inhibitor of matrix metalloproteinase 9 (MMP-9). Salvianolic acid A has antioxidant and anti-inflammatory activity and protects the blood-brain barrier.
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TargetMol | Inhibitor Hot
TAXUSIN
TN676319605-80-2
TAXUSIN is a natural product of the yew tree and has certain anticancer and analgesic activities.
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Thapsigargin
TQ030267526-95-8
Thapsigargin is a natural product, an inhibitor of sarcoplasmic endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer. Thapsigargin increases cytoplasmic calcium concentration by blocking the ability of cells to pump calcium into the sarcoplasmic and endoplasmic reticulum.
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(+/-)-Terreic acid
T21776L15255-24-0In house
(+ -)-Terreic acid is a natural product found in Kulturen v. Aspergillus flavipes.
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3,5,6-trihydroxysitostane
(24R)-Stigmastane-3β,5α,6α-triol
T84308133697-68-4In house
3,5,6-trihydroxysitostane is a steroid natural product derived from the fruits of Evodia rutaecarpa.
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Hydrangenol
TN4234480-47-7In house
Hydrangenol is a natural product and can be isolated from Hydrangea serrata leaves. Hydrangenol is an antiphotoaging compound with oral activity. Hydrangenol can reduce MMP and inflammatory cytokine expression and increase moisturizing factors and antioxidant genes level, result in preventing wrinkle formation.
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Koenimbine
TN615521087-98-9In house
Koenimbine is a natural product for research related to life sciences. The catalog number is TN6155 and the CAS number is 21087-98-9.
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2'-Aminoacetophenone
Fr14273551-93-9
Compound Fr14273 is a natural product for research related to life sciences. The catalog number is Fr14273 and the CAS number is 551-93-9.
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7-10 days
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2,3,5-Trimethylpyrazine
Fr1450014667-55-1
Compound Fr14500 is a natural product for research related to life sciences. The catalog number is Fr14500 and the CAS number is 14667-55-1.
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7-10 days
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Benzothiazolone
2-Benzothiazolol
Fr16664934-34-9
Compound Fr16664 is a natural product for research related to life sciences. The catalog number is Fr16664 and the CAS number is 934-34-9.
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2,6-Dihydroxyacetophenone
Fr16683699-83-2
Compound Fr16683 is a natural product for research related to life sciences. The catalog number is Fr16683 and the CAS number is 699-83-2.
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7-10 days
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Methylsyringol
PDK03276638-05-7
Methylsyringol is a natural product from Pinus yunnanensis.
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Colchicine
Colcin, Colchisol, Colchineos
T032064-86-8
Colchicine (Colcin) is a natural product that is an inhibitor of microtubule polymerization (IC50=3 nM) and blocks microtubule polymerization by binding to microtubule proteins. Colchicine can be used in the treatment of ventilation and rheumatic diseases.
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Artemisinin
Qinghaosu,Artemisinine, Qinghaosu, NSC 369397, Artemisinine
T039263968-64-9
Artemisinin (Qinghaosu) is a natural product, a sesquiterpene lactone, derived from Artemisia annua. Artemisinin has anti-malarial activity, as well as neuroprotective and anti-tumor activity.
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