Search Result

Search Results for " platelet "

Targets

Platelet aggregation

480

Compounds

121

Natural Products

231

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
TP2466	Platelet factor 4 (59-70)	PF4 (59-70)
	Platelet factor 4 (59-70) elicits human neutrophil & monocyte chemotaxis.
TP1667	Platelet Factor 4 (58-70), human
	Platelet Factor 4 (58-70), human is a polypeptide based on the 58-70 amino acid sequence of Platelet Factor 4 (pf-4) residues.
TP2198	Platelet Membrane Glycoprotein IIB Peptide (296-306)		Others
	GPllb is composed of a 125 Kd heavy chain that is disulfide-linked to a 23 Kd light chain. Hydropathicity analysis of the cDNA sequence indicates that GPllb is anchored to the platelet through a single transmembrane doma...		Others
T9030	SU4984		FGFR , IGF-1R , PDGFR
	SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).		FGFR , IGF-1R , PDGFR
T5036	Cangrelor tetrasodium		GPR , P2Y Receptor
	Cangrelor tetrasodium is a reversible and selective antagonist of platelet P2Y12, with prompt and potent antiplatelet effects.		GPR , P2Y Receptor
T6091	CP-673451		VEGFR , PDGFR , c-Kit
	CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than other angiogenic receptors.		VEGFR , PDGFR , c-Kit
T14137	AG 1295		PDGFR
	AG 1295, a selective inhibitor of platelet-derived growth factor receptor (PDGFR) tyrosine-kinase, effectively halts PDGFR autophosphorylation without impacting the autophosphorylation of the EGF receptor[1][2][3][4].		PDGFR
T6594	MNS		Syk , Src , p97
	MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.		Syk , Src , p97
T1265	Amrinone	Inamrinone,Inocor,Wincoram	TNF , PDE
	Amrinone (Inocor) is a positive inotropic cardiotonic (cardiotonic agent) with vasodilator properties, phosphodiesterase 3 inhibitory activity.		TNF , PDE
T5460	Mofezolac		COX
	Mofezolac (formerly known as Disopain or N-22) is a highly selective COX-1 (cyclooxygenase-1) inhibitor with COXs selectivity index > 6000		COX
T11339	Furegrelate sodium	U-63557A	PPAR
	Furegrelate sodium (U-63557A) is a selective thromboxane synthase inhibitor with oral activity. Furegrelate sodium(U-63557A) inhibits thromboxane A2 (TXA2) synthase in human platelet microsomes with an IC50 of 15 nM.		PPAR
T2629	UNC2881		TAM Receptor
	UNC2881 is a specific Mer tyrosine kinase inhibitor (IC50: 4.3 nM). It is about 83- and 58-fold higher selectivity than Axl and Tyro3, respectively.		TAM Receptor
T16975	TAK-593		VEGFR , PDGFR
	TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).		VEGFR , PDGFR
T15031	CYM50260		Others , LPL Receptor
	CYM50260 is a potent and exquisitely selective agonist of sphingosine-1-phosphate 4 receptor (S1P4-R, EC50= nM) with no activity against S1P1-R, S1P2-R, S1P3-R and S1P5-R.		Others , LPL Receptor
T5109	Avapritinib	BLU-285	PDGFR , c-Kit
	Avapritinib (BLU-285) is a dual inhibitor of the mutant KIT receptor (KIT D816V, IC50: 0.27 nM) and PDGFRα (PDGFRα D842V, IC50: 0.24 nM).		PDGFR , c-Kit
T26019	R59949	R-59949,R 59949	Others , PKC
	R59949 is used as a Diacylglycerol kinase (DGK) inhibitor.		Others , PKC
T6711	Tyrphostin AG1296	Tyrphostin AG 1296,AG 1296	Apoptosis , FGFR , FLT , PDGFR , c-Kit
	Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.		Apoptosis , FGFR , FLT , PDGFR , c-Kit
T4320	Flumatinib	HHGV678	Bcr-Abl , PDGFR , c-Kit
	Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.		Bcr-Abl , PDGFR , c-Kit
T0160	Anagrelide	Anagrelida,Xagrid,Anagrelidum	PDE
	Anagrelide (Xagrid) is a Platelet-reducing Agent. The mechanism of action of anagrelide is as a Phosphodiesterase 3 Inhibitor. The physiologic effect of anagrelide is by means of Decreased Platelet Production.		PDE
T7945	SU14813		VEGFR , PDGFR , c-Kit
	SU14813 is a multi-receptor tyrosine kinase inhibitor with potent antiangiogenesis and antitumor activity (IC50s of 50, 2, 4, 15 nM for VEGFR2, VEGFR1, PDGFRβ and KIT).		VEGFR , PDGFR , c-Kit
T6996	SU 5402	SU5402	VEGFR , FGFR , PDGFR
	SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.		VEGFR , FGFR , PDGFR
T5466	Tyrosine kinase-IN-1		VEGFR , FGFR , FLT , PDGFR
	Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor（KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively）		VEGFR , FGFR , FLT , PDGFR
T8900	Seralutinib	GB002	PDGFR
	Seralutinib (GB002) is an inhibitor of inhaled PDGFRα and PDGFRβ. It is used in the study for pulmonary arterial hypertension.		PDGFR
T6236	Ozagrel	OKY-046,Domenan	Thrombin , Prostaglandin Receptor
	Ozagrel (Domenan) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral isch...		Thrombin , Prostaglandin Receptor
T2415	PP121		Apoptosis , VEGFR , Bcr-Abl , PDGFR , Src , mTOR , Hck
	PP-121 is a multi-targeted inhibitor of PDGFR (IC50: 2 nM), Hck (IC50: 8 nM), mTOR (IC50: 10 nM), VEGFR2(IC50: 12 nM), Src (IC50: 14 nM) and Abl (IC50: 18 nM) , also inhibits DNA-PK (IC50: 60 nM).		Apoptosis , VEGFR , Bcr-Abl , PDGFR , Src , mTOR , Hck
T15047	Dacisteine	N,S-Diacetyl-L-cysteine	Others
	Dacisteine (N,S-Diacetyl-L-cysteine) is an inhibitor of New Delhi metallo-beta-lactamase-1 (NDM-1, IC50 = 1000 μM).		Others
T6166	Telatinib	Bay 57-9352	VEGFR , PDGFR , c-Kit
	Telatinib (Bay 57-9352) is an effective inhibitor of VEGFR2/3, c-Kit, and PDGFRα. The IC50s of Telatinib forVEGFR2/3, c-Kit and PDGFRα are 6 nM/4 nM, 1 nM, and 15 nM, respectively.		VEGFR , PDGFR , c-Kit
TQ0235	AC710		FLT , PDGFR , c-Kit
	AC710 is a potent PDGFR inhibitor (Kds: 0.6, 1, 1.57, 1.3, 1 nM for FLT3, KIT, CSF1R, PDGFRα and PDGFRβ).		FLT , PDGFR , c-Kit
T8719	SC99		Apoptosis , JAK , STAT
	SC99 is a selective inhibitor of JAK2-STAT3 activation. SC99 downregulates the expression of STAT3-modulated genes.SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activiti...		Apoptosis , JAK , STAT
T3570	SU4312	SU 4312,NSC 86429	VEGFR , PDGFR
	SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively). SU4312 (SU 4312) unexpectedly protects against MPP(+) -induced neurotox...		VEGFR , PDGFR
T10157	Regorafénib N-oxyde (M2)		Raf , VEGFR , c-RET , PDGFR , c-Kit , Drug Metabolite
	Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, RET, Kit, and Raf-1 (IC50s: 13/4.2/46, 1.5, 22, 7, and 2.5 nM).		Raf , VEGFR , c-RET , PDGFR , c-Kit , Drug Metabolite
T1452	Axitinib	AG-013736	VEGFR , PDGFR , c-Kit
	Axitinib (AG-013736) is an orally bioavailable tyrosine kinase inhibitor with IC50s of 0.1, 0.2, 0.1-0.3, 1.7, 1.6 nM for VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ, respectively.		VEGFR , PDGFR , c-Kit
T3476	JI-101	CGI-1842,JI 101	VEGFR , PDGFR , Ephrin Receptor
	JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets vascular endothelial growth factor receptor type 2 (VEGFR-2), platelet derived growth factor receptor β (PDGFR-β), and ephrin type-B receptor 4 (EphB4).		VEGFR , PDGFR , Ephrin Receptor
T1893	Parmodulin 2	ML 161	Protease-activated Receptor
	Parmodulin 2 (ML 161) is the inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50: 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). It also inhibits thromb...		Protease-activated Receptor
T6350	CHIR-124	CHIR124,CHIR 124	Apoptosis , GSK-3 , FLT , Chk , PDGFR , Src
	CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.		Apoptosis , GSK-3 , FLT , Chk , PDGFR , Src
T0435	Sulfinpyrazone	(+/-)-Sulfinpyrazone,G-28315,NSC 75925	COX
	Sulfinpyrazone (NSC-75925) is a uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.		COX
T0080	Trapidil	Rocornal,Trapymine,Avantrin,Trapymin,AR-12008	PDGFR , PDE
	Trapidil (Avantrin) is a coronary vasodilator agent. It was originally developed as a vasodilator and anti-platelet agent and has been used to treat patients with ischemic coronary heart, liver, and kidney disease.		PDGFR , PDE
T4190	Ticlopidine	PCR 5332,Ticlid	ATPase , Adiponectin receptor
	Ticlopidine (PCR 5332) is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor.		ATPase , Adiponectin receptor
T4191	Multi-kinase inhibitor 1	Multi-kinase inhibitor I	Others , Bcr-Abl , PDGFR , c-Kit
	Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.		Others , Bcr-Abl , PDGFR , c-Kit
T2500	Cediranib	AZD2171,NSC-732208	VEGFR , FLT , PDGFR , c-Kit , Autophagy
	Cediranib (AZD2171) (AZD2171) is a highly potent (IC50 < 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase in vitro, also inhibits Flt1/4 (IC50: 5 nM/≤3 nM), similar activity against PDGFRβ and c-Kit...		VEGFR , FLT , PDGFR , c-Kit , Autophagy
T13178	Toceranib	PHA 291639E,SU11654	VEGFR , PDGFR , c-Kit
	Toceranib (PHA 291639E) phosphate is an orally active inhibitor of tyrosine kinase (RTK) receptor, and it potently inhibits PDGFR, VEGFR, and Kit(with Kis of 5 and 6 nM for PDGFRβ and Flk-1/KDR, respectively), has antitu...		VEGFR , PDGFR , c-Kit
T6625	Ozagrel hydrochloride	Ozagrel HCl,OKY-046 HCl	Thrombin , Prostaglandin Receptor
	Ozagrel hydrochloride (OKY-046 HCl) is a selective thromboxane A(2) synthetase inhibitor used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.		Thrombin , Prostaglandin Receptor
T1777	Nintedanib	BIBF 1120,Intedanib	VEGFR , FGFR , FLT , PDGFR , Src
	Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/108 nM), PDGFRα, and PDGFRβ (IC50=59/65 nM). Nintedanib has an...		VEGFR , FGFR , FLT , PDGFR , Src
T1836	AZD2932		VEGFR , FLT , PDGFR , c-Kit
	AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.		VEGFR , FLT , PDGFR , c-Kit
T0097L	Pazopanib	GW786034	VEGFR , FGFR , PDGFR , c-Kit , Autophagy
	Pazopanib (GW786034), a small molecule inhibitor, inhibits multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits VEGFR-1, -2 and -3, c-kit and PDGF-R, which may result i...		VEGFR , FGFR , PDGFR , c-Kit , Autophagy
T1792L	Regorafenib monohydrate		Raf , VEGFR , c-RET , PDGFR , c-Kit , Autophagy
	Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, KIT, RET, RAF-1, B-RAF and B-RAF(V600E) respect...		Raf , VEGFR , c-RET , PDGFR , c-Kit , Autophagy
T6920	ON123300		FGFR , c-RET , JAK , CDK , PDGFR , Src , AMPK
	ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).		FGFR , c-RET , JAK , CDK , PDGFR , Src , AMPK
T16164	MY-5445	N-(3-chlorophenyl)-4-phenylphthalazin-1-amine	PDE
	MY-5445 (N-(3-chlorophenyl)-4-phenylphthalazin-1-amine) is a specific inhibitor of phosphodiesterase type 5 (PDE5). MY-5445 selectively inhibits cGMP PDE (Ki:1.3 μM).		PDE
T8976	PD-089828		EGFR , FGFR , PDGFR , Src
	PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 ...		EGFR , FGFR , PDGFR , Src
TQ0059	Ilorasertib	ABT-348	VEGFR , FLT , c-RET , PDGFR , Aurora Kinase
	Ilorasertib (ABT-348) (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C (IC50s: 120 nM/7 nM/1 nM). It also suppresses RET tyrosine kinase, PDGFRβ, and Flt1 (IC50s: ...		VEGFR , FLT , c-RET , PDGFR , Aurora Kinase

Compounds

Platelet factor 4 (59-70)

TP2466

Synonym: PF4 (59-70)

Target:

Platelet Factor 4 (58-70), human

TP1667

Synonym:

Target:

Platelet Membrane Glycoprotein IIB Peptide (296-306)

Target: FGFR, IGF-1R, PDGFR

cangrelor tetrasodium

T5036

Synonym:

Target: GPR, P2Y Receptor

CP-673451

T6091

Synonym:

Target: VEGFR, PDGFR, c-Kit

Target: Syk, Src, p97

Amrinone

T1265

Synonym: Inamrinone,Inocor,Wincoram

Target: Others, LPL Receptor

Synonym: R-59949,R 59949

Target: Others, PKC

Tyrphostin AG1296

T6711

Synonym: Tyrphostin AG 1296,AG 1296

Target: Apoptosis, FGFR, FLT, PDGFR, c-Kit

Flumatinib

T4320

Synonym: HHGV678

Target: Bcr-Abl, PDGFR, c-Kit

Anagrelide

T0160

Synonym: Anagrelida,Xagrid,Anagrelidum

Target: VEGFR, PDGFR, c-Kit

SU 5402

T6996

Synonym: SU5402

Target: VEGFR, FGFR, PDGFR

Tyrosine kinase-IN-1

T5466

Synonym:

Target: VEGFR, FGFR, FLT, PDGFR

Synonym: OKY-046,Domenan

Target: Thrombin, Prostaglandin Receptor

PP121

T2415

Synonym:

Target: Apoptosis, VEGFR, Bcr-Abl, PDGFR, Src, mTOR, Hck

Dacisteine

T15047

Synonym: N,S-Diacetyl-L-cysteine

Target: VEGFR, PDGFR, c-Kit

AC710

TQ0235

Synonym:

Target: FLT, PDGFR, c-Kit

SC99

T8719

Synonym:

Target: Apoptosis, JAK, STAT

SU4312

T3570

Synonym: SU 4312,NSC 86429

Target: VEGFR, PDGFR

Regorafénib N-oxyde (M2)

T10157

Synonym:

Target: Raf, VEGFR, c-RET, PDGFR, c-Kit, Drug Metabolite

Axitinib

T1452

Synonym: AG-013736

Target: VEGFR, PDGFR, c-Kit

JI-101

T3476

Synonym: CGI-1842,JI 101

Target: VEGFR, PDGFR, Ephrin Receptor

Parmodulin 2

T1893

Synonym: ML 161

Target: Protease-activated Receptor

CHIR-124

T6350

Synonym: CHIR124,CHIR 124

Target: Apoptosis, GSK-3, FLT, Chk, PDGFR, Src

Sulfinpyrazone

T0435

Synonym: (+/-)-Sulfinpyrazone,G-28315,NSC 75925

Target: COX

Trapidil

T0080

Synonym: Rocornal,Trapymine,Avantrin,Trapymin,AR-12008

Target: PDGFR, PDE

Ticlopidine

T4190

Synonym: PCR 5332,Ticlid

Target: ATPase, Adiponectin receptor

Multi-kinase inhibitor 1

T4191

Synonym: Multi-kinase inhibitor I

Target: Others, Bcr-Abl, PDGFR, c-Kit

Cediranib

T2500

Synonym: AZD2171,NSC-732208

Target: VEGFR, FLT, PDGFR, c-Kit, Autophagy

Toceranib

T13178

Synonym: PHA 291639E,SU11654

Target: VEGFR, PDGFR, c-Kit

Ozagrel hydrochloride

T6625

Synonym: Ozagrel HCl,OKY-046 HCl

Target: Thrombin, Prostaglandin Receptor

Nintedanib

T1777

Synonym: BIBF 1120,Intedanib

Target: VEGFR, FGFR, FLT, PDGFR, Src

AZD2932

T1836

Synonym:

Target: VEGFR, FLT, PDGFR, c-Kit

Pazopanib

T0097L

Synonym: GW786034

Target: VEGFR, FGFR, PDGFR, c-Kit, Autophagy

Regorafenib monohydrate

T1792L

Synonym:

Target: Raf, VEGFR, c-RET, PDGFR, c-Kit, Autophagy

ON123300

T6920

Synonym:

Target: FGFR, c-RET, JAK, CDK, PDGFR, Src, AMPK

MY-5445

T16164

Synonym: N-(3-chlorophenyl)-4-phenylphthalazin-1-amine

Target: EGFR, FGFR, PDGFR, Src

Ilorasertib

TQ0059

Synonym: ABT-348

Target: VEGFR, FLT, c-RET, PDGFR, Aurora Kinase

Cat No.	Product Name	Synonyms	Targets
TN2085	Piperlonguminine		Anti-infection , Antibacterial , Antifungal
	Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibacterial activities.Piperl...		Anti-infection , Antibacterial , Antifungal
T6S0139	Neobavaisoflavone		Apoptosis , DNA/RNA Synthesis
	1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si...		Apoptosis , DNA/RNA Synthesis
T2734	Sennoside B		PDGFR
	Sennoside B is an anthranoid. Anthranoid derivatives are used all over the world as a treatment for constipation.		PDGFR
T3781	Jujuboside B		Others
	Jujuboside B has potent inhibitory effects on collagen-, thrombin-, AA-, and ADP-induced aggregation, and also exhibits superior protection on the thromboembolic model.		Others
T3S1591	Notoginsenoside Fc		Others , Autophagy
	1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect.		Others , Autophagy
T0853	Adenosine	D-Adenosine,Adenine riboside	Apoptosis , Nucleoside Antimetabolite/Analog , Endogenous Metabolite , Autophagy
	Adenosine (D-Adenosine) is a ribonucleoside comprised of adenine bound to ribose, with vasodilatory, antiarrhythmic and analgesic activities.
TN1969	N-(p-Coumaroyl) serotonin		PDGFR
	N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower. N-(p-Coumaroyl) serotonin has antioxidant, cardioprotective effects after ischemia and antitumor activity, it may be beneficial in improving...		PDGFR
TN2244	Sulfuretin		NF-κB , Autophagy
	Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 thr...		NF-κB , Autophagy
TN1926	Methyl caffeate	Methyl caffeate acid	Others , Antibacterial
	Methyl caffeate (Methyl caffeate acid) acid		Others , Antibacterial
T8288	14-Deoxyandrographolide		Apoptosis , Others
	14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy. It desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release.		Apoptosis , Others
T1626	Prostaglandin E1	PGE1,Alprostadil	Endogenous Metabolite , Prostaglandin Receptor
	Prostaglandin E1 (Alprostadil) is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Prostaglandin E1 is a potent vasodilator agent that increases peripheral blood flow, in...		Endogenous Metabolite , Prostaglandin Receptor
TN2354	Methylnissolin	3-Hydroxy-9,10-dimethoxyptercarpan	ERK , PDGFR
	Methylnissolin (3-Hydroxy-9,10-dimethoxyptercarpan) is derived from Astragalus and has antibacterial and anti-cancer effects.		ERK , PDGFR
TN4222	Homoeriodictyol 7-O-β-D-glucoside	Homoeriodictyol 7-O-glucoside	Others , Platelet aggregation
	Homoeriodictyol 7-O-β-D-glucoside (Homoeriodictyol 7-O-glucoside) is a natural product from Viscum coloratum(Kom.)Nakai. Homoeriodictyol 7-O-β-D-glucoside is an antagonist of platelet-activating factor (PAF).		Others , Platelet aggregation
TN6924	Anhydrosafflor yellow B	(2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1,AHSYB	Others
	Anhydrosafflor yellow B ((2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,...		Others
T28551	Ro 09-0680	Ro 09 0680,Ro-09-0680
	Ro 09-0680 is an inhibitor of platelet aggregation.
T5S2358	Dehydrocorydaline	Dehydrocorydalin,13-Methylpalmatine	BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
	1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimeriz...		BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
T3817	Darutigenol		Others
	Darutigenol has obvious antithrombotic effect, its mechanism may be related to inhibition of platelet aggregation and adhesion.		Others
TMA0536	2-Acetylbenzoic acid		Prostaglandin Receptor
	2-Acetylbenzoic acid is more potent than 2-propionyloxybenzoic acid in inhibiting platelet function and platelet prostaglandin (PG) synthesis although the potencies of these agents were comparable in inhibiting prostacyc...		Prostaglandin Receptor
TN2343	Pseudojervine	Jervin-3-glucoside,O-beta-D-Glucopyranosyljervine	Platelet aggregation
	Pseudojervine (O-beta-D-Glucopyranosyljervine) is derived from Veratrum nigrum L. Pseudojervine exhibits feeble inhibition activity against platelet aggregation.		Platelet aggregation
T12164	N6-(4-Hydroxybenzyl)adenosine	Para-topolin riboside	P2Y Receptor
	N6-(4-Hydroxybenzyl)adenosine (Para-topolin riboside) is a platelet aggregation inhibitor.		P2Y Receptor
T1723	Adenosine 5'-diphosphate	Adenosine diphosphate,adenosine pyrophosphate,ADP	Endogenous Metabolite
	Adenosine 5'-diphosphate (ADP) induces human platelet aggregation and non-competitively blocks the stimulated human platelet adenylate cyclase.		Endogenous Metabolite
TQ0036	Anemarrhenasaponin I		Others
	Anemarrhenasaponin I shows the remarkable inhibiting effect on platelet aggregation.		Others
TN1643	Ferulamide	4-Hydroxy-3-methoxycinnamide	PAFR , AChR
	Ferulamide (4-Hydroxy-3-methoxycinnamide), a Ferulic acid derivative, shows potent inhibitory activity against arachidonic acid-induced platelet aggregation.		PAFR , AChR
TN1057	Veratrosine	Veratramine 3-glycoside,Veratramine-beta-D-glucoside	Platelet aggregation
	Veratrosine (Veratramine-beta-D-glucoside) is an alkaloid isolated from the herbs of Veratrum nigrum. Veratrosine exhibits feeble inhibition activity against platelet aggregation.		Platelet aggregation
T11012	Dextran	Dextran 40	Platelet aggregation
	Dextran has an inhibitory effect on platelet aggregation and coagulation factors, and is used as an agent for increasing plasma volume.		Platelet aggregation
TN1873	Lirinidine		Others
	(+)-Lirinidine has antioxidative activity, and it can significantly inhibit the proliferation of melanoma cells; it also shows potent inhibition of melanogenesis. Lirinidine exhibits significant inhibition of collagen, a...		Others
T2898	Andrographolide	Andrographis	SARS-CoV , Influenza Virus , NF-κB , Autophagy
	Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potential antineoplastic.		SARS-CoV , Influenza Virus , NF-κB , Autophagy
T5S0896	Loureirin A		Akt , PI3K
	Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related pept...		Akt , PI3K
TN6710	Methyl acetylsalicylate	ACETYLSALICYLIC ACID METHYL ESTER	Others
	Methyl acetylsalicylate (ACETYLSALICYLIC ACID METHYL ESTER) is a natural product isolated from Pisum sativum. Inhibition of collagen-induced human platelet rich plasma aggregation		Others
T3429	Protopine	Macleyine,Hypercorine,Corydinine,Biflorine,Fumarine	Reactive Oxygen Species , Platelet aggregation , Histamine Receptor
	Protopine (Fumarine) is a benzylisoquinoline alkaloid. It has been found to inhibit histamine H1 receptors and platelet aggregation, and acts as an analgesic.
TN2315	Xanthopurpurin		Platelet aggregation , Antifection
	Xanthopurpurin shows antiviral activity. Xanthopurpurin can effectively inhibit rotavirus multiplication by promoting virus-induced apoptosis in MA-104 cells. Xanthopurpurin shows mainly strong inhibition of collagen-ind...		Platelet aggregation , Antifection
T3408	Syringin	Lilacin,Syringoside,eleutheroside-b,Methoxyconiferine	NOS , Autophagy
	Syringin (eleutheroside-b) is a compound with antitumor, antiproliferative, immunomodulatory and platelet aggregation inhibiting effects.		NOS , Autophagy
T3734	3',4'-Dihydroxyacetophenone	Qingxintong,4-Acetylpyrocatechol	Tyrosinase , Platelet aggregation
	3',4'-Dihydroxyacetophenone (Qingxintong) is an active constituent of Chinese medicine. It is platelet aggregation Inhibitor and also has anti-arrhythmia activity.		Tyrosinase , Platelet aggregation
T5079	Adenosine 5'-diphosphate sodium salt	Adenosine-5'-diphosphate trisodium salt,ADP sodium salt	Others , Endogenous Metabolite
	Adenosine 5'-diphosphate sodium salt (ADP sodium salt) is an adenine nucleotide that is phosphorylated into ATP by ATPase. This phosphorylation is a key part of cellular homeostatis as it allows for energy storage and is...		Others , Endogenous Metabolite
T4S1658	Benzoyloxypaeoniflorin	Benzoyloxypeoniflorin	NF-κB , Tyrosinase
	Benzoyloxypaeoniflorin (Benzoyloxypeoniflorin) is a natural product,contributes to improving blood circulation through their inhibitory effects on both platelet aggregation and blood coagulation.		NF-κB , Tyrosinase
TN1383	Timosaponin B III	Anemarsaponin BIII	Others , Platelet aggregation
	Timosaponin B III (Anemarsaponin BIII) is a bioactive steroidal saponin isolated from Anemarrhena asphodeloides Bge. Timosaponin B III possesses anti-inflammatory, anti-platelet aggregative and anti-depressive effects.		Others , Platelet aggregation
T7053	P-Hydroxycinnamic acid	p-Coumaric acid,p-Cumaric acid,p-Hydroxy-cinnamic acid,NSC 59260	Thrombin , Endogenous Metabolite , Prostaglandin Receptor
	p-Hydroxycinnamic acid (NSC-59260) can inhibit platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively.		Thrombin , Endogenous Metabolite , Prostaglandin Receptor
T0131	Cepharanthine	NSC-623442	Apoptosis , TNF , HIV Protease , Autophagy
	Cepharanthine (NSC-623442), a biscoclaurine alkaloid, suppresses tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and inhibits cytokine production.		Apoptosis , TNF , HIV Protease , Autophagy
TN3460	Asebogenin		Antifungal
	Asebogenin is a compound fractionated from Salvia miltiorrhiza with antifungal activity, inhibition of GPVI-induced platelet reactions, and inhibition of NET formation induced by pro-inflammatory stimuli.		Antifungal
TJS0314	5,7-Dihydroxy-4-methylcoumarin	Methyl-2H-Chromen-2-One,4-Methyllimetol,4-Methyl-5,7-Dihydroxycoumarin	Others , Antibacterial , Antifungal
	5,7-Dihydroxy-4-methylcoumarin (Methyl-2H-Chromen-2-One) inhibits human neutrophil oxidative metabolism and elastase activity. 5,7-Dihydroxy-4-methylcoumarin has in vitro platelet antiaggregatory property. 5,7-Dihydroxy-...		Others , Antibacterial , Antifungal
T2S1749	Protogracillin		Others
	Protogracillin may have inhibitions on platelet aggregation (PAG) and thrombosis.		Others
T0070	Pentoxifylline	Oxpentifylline,PTX,BL-191	HIV Protease , PDE , Adenosine Receptor , Autophagy
	Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It also inhibits platelet ...		HIV Protease , PDE , Adenosine Receptor , Autophagy
T6943	Picropodophyllin	AXL1717,Picropodophyllin (PPP),Picropodophyllotoxin,PPP	Apoptosis , IGF-1R
	Picropodophyllin (Picropodophyllin (PPP)) (PPP) is a specific IGF-1R inhibitor (IC50: 1 nM). Picropodophyllin specifically inhibits the activity and downregulates the cellular expression of IGF1R without interfering with...		Apoptosis , IGF-1R
T2939	Forskolin	Coleonol,Colforsin	FXR , Adenylyl cyclase , AChR , Autophagy
	Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM). Forskolin increases cAMP levels, activates PXR and FXR, and induces autophagy. Forskolin produces positive inotropic effects in the...		FXR , Adenylyl cyclase , AChR , Autophagy
TN2322	Yangambin		Calcium Channel , PAFR
	Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibiti...		Calcium Channel , PAFR
TN1170	1-Cinnamoylpyrrolidine		Platelet aggregation
	1-Cinnamoylpyrrolidine, a natural product prepared from Piper caninum, can be used as a DNA strand breaking agent, inducing the relaxation of the plasmid pBR322 DNA superhelix in the presence of Cu2+. 1-Cinnamoylpyrrolid...		Platelet aggregation
TN6975	Cirsiumaldehyde	5,5’-oxydimethylenebis(2-furfural)	Platelet aggregation
	Cirsiumaldehyde is a compound isolated from the mature fruits of Lobelia chinensis, Cornus officinalis, and the fruits of Hippophae rhamnoides.Cirsiumaldehyde in the presence of collagen inhibited U46619-induced (1~5 uM)...		Platelet aggregation
TL0001	Dencichine	L-Dencichin,ODAP,Dencichin	Others , HIF/HIF Prolyl-Hydroxylase
	Dencichine (ODAP) is a neurotoxic agent. Dencichine is a haemostatic agent, the hemostatic effect relates to modulation of the coagulation system, platelet aggregation and fibrinolytic system. It has renoprotective effec...		Others , HIF/HIF Prolyl-Hydroxylase
T3S0645	N-trans-Feruloyltyramine	Feruloyltyramine,N-Feruloyltyramine,Moupinamide	Others , COX
	1. N-trans-Feruloyltyramine (Feruloyltyramine)(NTF) has hepatoprotective effect. 2. NTF has antioxidative activity against Aβ(1-42)-induced neuronal death. 3. NTF is likely to inhibit COX enzymes, thereby suppressing P-s...		Others , COX
T7030	Anemarsaponin B		p38 MAPK , NF-κB , MEK , COX , NO Synthase
	Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B c...		p38 MAPK , NF-κB , MEK , COX , NO Synthase
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Natural Products

Piperlonguminine

TN2085

Synonym:

Target: Anti-infection, Antibacterial, Antifungal

Neobavaisoflavone

T6S0139

Synonym:

Target: Apoptosis, DNA/RNA Synthesis

Target: Others, Autophagy

Adenosine

T0853

Synonym: D-Adenosine,Adenine riboside

Target: Apoptosis, Nucleoside Antimetabolite/Analog, Endogenous Metabolite, Autophagy

N-(p-Coumaroyl) serotonin

Target: NF-κB, Autophagy

Methyl caffeate

TN1926

Synonym: Methyl caffeate acid

Target: Others, Antibacterial

14-Deoxyandrographolide

T8288

Synonym:

Target: Apoptosis, Others

Prostaglandin E1

T1626

Synonym: PGE1,Alprostadil

Target: Endogenous Metabolite, Prostaglandin Receptor

Methylnissolin

TN2354

Synonym: 3-Hydroxy-9,10-dimethoxyptercarpan

Target: ERK, PDGFR

Homoeriodictyol 7-O-β-D-glucoside

TN4222

Synonym: Homoeriodictyol 7-O-glucoside

Target: Others, Platelet aggregation

Anhydrosafflor yellow B

TN6924

Synonym: (2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1,AHSYB

Target: Others

Ro 09-0680

T28551

Synonym: Ro 09 0680,Ro-09-0680

Target:

Dehydrocorydaline

T5S2358

Synonym: Dehydrocorydalin,13-Methylpalmatine

Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy

Target: Prostaglandin Receptor

Pseudojervine

TN2343

Synonym: Jervin-3-glucoside,O-beta-D-Glucopyranosyljervine

Target: Platelet aggregation

N6-(4-Hydroxybenzyl)adenosine

T12164

Synonym: Para-topolin riboside

Target: P2Y Receptor

Adenosine 5'-diphosphate

T1723

Synonym: Adenosine diphosphate,adenosine pyrophosphate,ADP

Target: Endogenous Metabolite

Synonym: 4-Hydroxy-3-methoxycinnamide

Target: PAFR, AChR

Veratrosine

TN1057

Synonym: Veratramine 3-glycoside,Veratramine-beta-D-glucoside

Target: Platelet aggregation

Dextran

T11012

Synonym: Dextran 40

Target: Platelet aggregation

Synonym: Andrographis

Target: SARS-CoV, Influenza Virus, NF-κB, Autophagy

Methyl acetylsalicylate

TN6710

Synonym: ACETYLSALICYLIC ACID METHYL ESTER

Target: Others

Protopine

T3429

Synonym: Macleyine,Hypercorine,Corydinine,Biflorine,Fumarine

Target: Reactive Oxygen Species, Platelet aggregation, Histamine Receptor

Xanthopurpurin

TN2315

Synonym:

Target: Platelet aggregation, Antifection

Syringin

T3408

Synonym: Lilacin,Syringoside,eleutheroside-b,Methoxyconiferine

Target: NOS, Autophagy

3',4'-Dihydroxyacetophenone

T3734

Synonym: Qingxintong,4-Acetylpyrocatechol

Target: Tyrosinase, Platelet aggregation

Adenosine 5'-diphosphate sodium salt

T5079

Synonym: Adenosine-5'-diphosphate trisodium salt,ADP sodium salt

Target: Others, Endogenous Metabolite

Benzoyloxypaeoniflorin

T4S1658

Synonym: Benzoyloxypeoniflorin

Target: NF-κB, Tyrosinase

Timosaponin B III

TN1383

Synonym: Anemarsaponin BIII

Target: Others, Platelet aggregation

p-Hydroxycinnamic acid

T7053

Synonym: p-Coumaric acid,p-Cumaric acid,p-Hydroxy-cinnamic acid,NSC 59260

Target: Thrombin, Endogenous Metabolite, Prostaglandin Receptor

Cepharanthine

T0131

Synonym: NSC-623442

Target: Apoptosis, TNF, HIV Protease, Autophagy

5,7-Dihydroxy-4-methylcoumarin

TJS0314

Synonym: Methyl-2H-Chromen-2-One,4-Methyllimetol,4-Methyl-5,7-Dihydroxycoumarin

Target: Others, Antibacterial, Antifungal

Synonym: Oxpentifylline,PTX,BL-191

Target: HIV Protease, PDE, Adenosine Receptor, Autophagy

Picropodophyllin

T6943

Synonym: AXL1717,Picropodophyllin (PPP),Picropodophyllotoxin,PPP

Target: Apoptosis, IGF-1R

Forskolin

T2939

Synonym: Coleonol,Colforsin

Target: FXR, Adenylyl cyclase, AChR, Autophagy

Yangambin

TN2322

Synonym:

Target: Calcium Channel, PAFR

1-Cinnamoylpyrrolidine

TN1170

Synonym:

Target: Platelet aggregation

Cirsiumaldehyde

TN6975

Synonym: 5,5’-oxydimethylenebis(2-furfural)

Target: Platelet aggregation

dencichine

TL0001

Synonym: L-Dencichin,ODAP,Dencichin

Target: Others, HIF/HIF Prolyl-Hydroxylase

N-trans-Feruloyltyramine

T3S0645

Synonym: Feruloyltyramine,N-Feruloyltyramine,Moupinamide

Target: p38 MAPK, NF-κB, MEK, COX, NO Synthase

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04644	PDGFB Protein, Human, Recombinant (His)	Human	Yeast
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit...
TMPY-01139	PDGFRA Protein, Human, Recombinant (His)	Human	HEK293
	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-04976	PDGFC Protein, Mouse, Recombinant (His)	Mouse	Yeast
	PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPY-05034	CD42b/GP1BA Protein, Human, Recombinant (His)	Human	HEK293
	CD42b/GP1BA Protein, Human, Recombinant (His) is expressed in HEK293 cells.
TMPY-00970	CD31/PECAM-1 Protein, Human, Recombinant (His)	Human	HEK293
	The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transm...
TMPY-03234	CD42c Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Platelet glycoprotein Ib (GPIb) complex is best known as a major platelet receptor for von Willebrand factor essential for platelet adhesion under high shear conditions found in arteries and thrombosis. The GPIb complex ...
TMPY-00624	PEAR1 Protein, Rat, Recombinant (His)	Rat	Baculovirus-Insect Cells
	Platelet endothelial aggregation receptor-1 (PEAR1), an epidermal growth factor repeat-containing transmembrane receptor, is known to participate in platelet contact-induced activation. Platelet endothelial aggregation r...
TMPY-05068	PDGFA Protein, Rat, Recombinant (His)	Rat	Yeast
	Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell prolifera...
TMPY-05075	PDGFA Protein, Canine, Recombinant (His)	Canine	Yeast
	Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell prolifera...
TMPY-05077	PDGFB Protein, Rhesus, Recombinant (His)	Rhesus	Yeast
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit...
TMPY-05076	PDGFB Protein, Canine, Recombinant (His)	Canine	Yeast
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit...
TMPY-00455	PDGFA Protein, Canine, Recombinant (hFc)	Canine	HEK293
	Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell prolifera...
TMPY-04838	PDGFA Protein, Mouse, Recombinant (His)	Mouse	Yeast
	Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell prolifera...
TMPY-02395	PDGFB Protein, Cynomolgus, Recombinant (mFc)	Cynomolgus	HEK293
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit...
TMPY-03140	PDGFRB Protein, Rat, Recombinant (His)	Rat	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-00385	PDGFRB Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-00269	PDGFC Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293
	PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPY-01218	CD42c Protein, Human, Recombinant (His)	Human	HEK293
	Platelet glycoprotein Ib (GPIb) complex is best known as a major platelet receptor for von Willebrand factor essential for platelet adhesion under high shear conditions found in arteries and thrombosis. The GPIb complex ...
TMPY-06921	PDGFRA Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-03590	PDGFRB Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-03474	PDGFRB Protein, Rat, Recombinant (hFc)	Rat	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-03825	PDGFRA Protein, Rat, Recombinant (His)	Rat	HEK293
	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-03919	PDGFRA Protein, Rat, Recombinant (hFc)	Rat	HEK293
	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPJ-00605	GPVI Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Glycoprotein VI (GPVI) is a 63 kDa platelet/megakaryocyte-specific type I transmembrane glycoprotein of the immunoglobulin superfamily that is an important collagen receptor and initiator of platelet activation, aggregat...
TMPY-04877	PDGFB Protein, Mouse, Recombinant (His)	Mouse	Yeast
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit...
TMPY-05056	PDGFA Protein, Human, Recombinant (His)	Human	Yeast
	Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell prolifera...
TMPY-02815	PDGFC Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPY-00741	CXCL4 Protein, Human, Recombinant	Human	E. coli
	Platelet factor 4 (PF4), also known as chemokine (C-X-C motif) ligand 4 (CXCL4), is a small cytokine belonging to the CXC chemokine family. CXCL4/PF4 is released from the alpha-granules of activated platelets and binds w...
TMPY-00898	PDGFC Protein, Human, Recombinant (hFc)	Human	HEK293
	PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPY-05160	PFKP Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	PFKP plays a critical role in cell proliferation in breast cancer cells. PFKP is necessary for starvation-mediated autophagy, glycolysis, and EMT, thereby promoting the malignant progression of OSCC. The Snail-PFKP axis ...
TMPH-00213	Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc)	Bothrops atrox	E. coli
	Inhibits fibrinogen interaction with platelets. Acts by binding to the glycoprotein IIb-IIIa receptor (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor a...
TMPY-05789	PDGFRA Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-05608	PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-05787	PDGFRA Protein, Mouse, Recombinant (His)	Mouse	HEK293
	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-00900	PDGFRA Protein, Human, Recombinant (hFc)	Human	HEK293
	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-02251	PDGFC Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPY-02681	CXCL7 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Pro-platelet basic protein (PPBP) is also known as Chemokine (C-X-C motif) ligand 7 (CXCL7) and nucleosome assembly protein (Nap-2). Nap-2 / PPBP / CXCL7 is released in large amounts from platelets following their activa...
TMPY-04724	CXCL7 Protein, Rat, Recombinant (His)	Rat	Yeast
	Pro-platelet basic protein (PPBP) is also known as Chemokine (C-X-C motif) ligand 7 (CXCL7) and nucleosome assembly protein (Nap-2). Nap-2 / PPBP / CXCL7 is released in large amounts from platelets following their activa...
TMPY-04622	PF4V1 Protein, Human, Recombinant (mFc)	Human	HEK293
	PF4V1 Protein, Human, Recombinant (mFc) is expressed in HEK293 with mFc tag. The predicted molecular weight is 34.6 kDa. Accession number: P10720
TMPY-03043	CXCL7 Protein, Cynomolgus, Recombinant (mFc)	Cynomolgus	HEK293
	Pro-platelet basic protein (PPBP) is also known as Chemokine (C-X-C motif) ligand 7 (CXCL7) and nucleosome assembly protein (Nap-2). Nap-2 / PPBP / CXCL7 is released in large amounts from platelets following their activa...
TMPY-04725	CXCL7 Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	Yeast
	Pro-platelet basic protein (PPBP) is also known as Chemokine (C-X-C motif) ligand 7 (CXCL7) and nucleosome assembly protein (Nap-2). Nap-2 / PPBP / CXCL7 is released in large amounts from platelets following their activa...
TMPY-01619	CD31/PECAM-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transm...
TMPJ-00433	VSIR Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Human Cells
	platelet receptor Gi24 is a single-pass type I membrane protein, and located at the cell surface. The protein can be cleaved by MMP14, and stimulate MMP14-mediated MMP2 activation. It is participated in the BMP signaling...
TMPJ-00293	CD36 Protein, Mouse, Recombinant (Avi & His), Biotinylated	Mouse	Human Cells
	Platelet Glycoprotein 4(CD36) is belongs to the class B scavenger receptor family. The molecule CD36 is synthesized as a 472 amino acid (aa) protein that contains a 6 aa N-terminal cytoplasmic domain, a 22 aa N-terminal ...
TMPJ-00294	CD36 Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	Platelet Glycoprotein 4(CD36) is belongs to the class B scavenger receptor family. The molecule CD36 is synthesized as a 472 amino acid (aa) protein that contains a 6 aa N-terminal cytoplasmic domain, a 22 aa N-terminal ...
TMPY-00706	CD31/PECAM-1 Protein, Human, Recombinant (hFc)	Human	HEK293
	The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transm...
TMPY-04937	PDGFRB Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05358	PDGFRB Protein, Human, Recombinant	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-01207	PDGFRB Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05497	PDGFRB Protein, Human, Recombinant (hFc)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
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PDGFB Protein, Human, Recombinant (His)

TMPY-04644

Species: Human

Expression System: Yeast

PDGFRA Protein, Human, Recombinant (His)

TMPY-01139

Species: Human

Expression System: HEK293

PDGFC Protein, Mouse, Recombinant (His)

TMPY-04976

Species: Mouse

Expression System: Yeast

CD42b/GP1BA Protein, Human, Recombinant (His)

TMPY-05034

Species: Human

Expression System: HEK293

CD31/PECAM-1 Protein, Human, Recombinant (His)

TMPY-00970

Species: Human

Expression System: HEK293

CD42c Protein, Rat, Recombinant (hFc)

TMPY-03234

Species: Rat

Expression System: HEK293

PEAR1 Protein, Rat, Recombinant (His)

TMPY-00624

Species: Rat

Expression System: Baculovirus-Insect Cells

PDGFA Protein, Rat, Recombinant (His)

TMPY-05068

Species: Rat

Expression System: Yeast

PDGFA Protein, Canine, Recombinant (His)

TMPY-05075

Species: Canine

Expression System: Yeast

PDGFB Protein, Rhesus, Recombinant (His)

TMPY-05077

Species: Rhesus

Expression System: Yeast

PDGFB Protein, Canine, Recombinant (His)

TMPY-05076

Species: Canine

Expression System: Yeast

PDGFA Protein, Canine, Recombinant (hFc)

TMPY-00455

Species: Canine

Expression System: HEK293

PDGFA Protein, Mouse, Recombinant (His)

TMPY-04838

Species: Mouse

Expression System: Yeast

PDGFB Protein, Cynomolgus, Recombinant (mFc)

TMPY-02395

Species: Cynomolgus

Expression System: HEK293

PDGFRB Protein, Rat, Recombinant (His)

TMPY-03140

Species: Rat

Expression System: HEK293

PDGFRB Protein, Rhesus, Recombinant (hFc)

TMPY-00385

Species: Rhesus

Expression System: HEK293

PDGFC Protein, Cynomolgus, Recombinant (hFc)

TMPY-00269

Species: Cynomolgus

Expression System: HEK293

CD42c Protein, Human, Recombinant (His)

TMPY-01218

Species: Human

Expression System: HEK293

PDGFRA Protein, Cynomolgus, Recombinant (His)

TMPY-06921

Species: Cynomolgus

Expression System: HEK293

PDGFRB Protein, Rhesus, Recombinant (His)

TMPY-03590

Species: Rhesus

Expression System: HEK293

PDGFRB Protein, Rat, Recombinant (hFc)

TMPY-03474

Species: Rat

Expression System: HEK293

PDGFRA Protein, Rat, Recombinant (His)

TMPY-03825

Species: Rat

Expression System: HEK293

PDGFRA Protein, Rat, Recombinant (hFc)

TMPY-03919

Species: Rat

Expression System: HEK293

GPVI Protein, Mouse, Recombinant (His)

TMPJ-00605

Species: Mouse

Expression System: Human Cells

PDGFB Protein, Mouse, Recombinant (His)

TMPY-04877

Species: Mouse

Expression System: Yeast

PDGFA Protein, Human, Recombinant (His)

TMPY-05056

Species: Human

Expression System: Yeast

PDGFC Protein, Human, Recombinant (His)

TMPY-02815

Species: Human

Expression System: Baculovirus-Insect Cells

CXCL4 Protein, Human, Recombinant

TMPY-00741

Species: Human

Expression System: E. coli

PDGFC Protein, Human, Recombinant (hFc)

TMPY-00898

Species: Human

Expression System: HEK293

PFKP Protein, Human, Recombinant (His & GST)

TMPY-05160

Species: Human

Expression System: Baculovirus-Insect Cells

Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc)

TMPH-00213

Species: Bothrops atrox

Expression System: E. coli

PDGFRA Protein, Mouse, Recombinant (hFc)

TMPY-05789

Species: Mouse

Expression System: HEK293

PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-05608

Species: Human

Expression System: HEK293

PDGFRA Protein, Mouse, Recombinant (His)

TMPY-05787

Species: Mouse

Expression System: HEK293

PDGFRA Protein, Human, Recombinant (hFc)

TMPY-00900

Species: Human

Expression System: HEK293

PDGFC Protein, Mouse, Recombinant (hFc)

TMPY-02251

Species: Mouse

Expression System: HEK293

CXCL7 Protein, Rat, Recombinant (hFc)

TMPY-02681

Species: Rat

Expression System: HEK293

CXCL7 Protein, Rat, Recombinant (His)

TMPY-04724

Species: Rat

Expression System: Yeast

PF4V1 Protein, Human, Recombinant (mFc)

TMPY-04622

Species: Human

Expression System: HEK293

CXCL7 Protein, Cynomolgus, Recombinant (mFc)

TMPY-03043

Species: Cynomolgus

Expression System: HEK293

CXCL7 Protein, Cynomolgus, Rhesus, Recombinant (His)

TMPY-04725

Species: Cynomolgus,Rhesus

Expression System: Yeast

CD31/PECAM-1 Protein, Mouse, Recombinant (His)

TMPY-01619

Species: Mouse

Expression System: HEK293

VSIR Protein, Cynomolgus, Recombinant (His)

TMPJ-00433

Species: Cynomolgus

Expression System: Human Cells

CD36 Protein, Mouse, Recombinant (Avi & His), Biotinylated

TMPJ-00293

Species: Mouse

Expression System: Human Cells

CD36 Protein, Mouse, Recombinant (hFc)

TMPJ-00294

Species: Mouse

Expression System: Human Cells

CD31/PECAM-1 Protein, Human, Recombinant (hFc)

TMPY-00706

Species: Human

Expression System: HEK293

PDGFRB Protein, Human, Recombinant (His), Biotinylated

TMPY-04937

Species: Human

Expression System: HEK293

PDGFRB Protein, Human, Recombinant

TMPY-05358

Species: Human

Expression System: HEK293

PDGFRB Protein, Human, Recombinant (His)

TMPY-01207

Species: Human

Expression System: HEK293

PDGFRB Protein, Human, Recombinant (hFc)

TMPY-05497

Species: Human

Expression System: HEK293

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Cat No.	Product Name
L5400	Anti-Cardiovascular Disease Compound Library		1428 compounds
	A unique collection of 1428 cardiovascular diseases related compounds for high throughput screening (HTS) and high content screening (HCS);

Libraries

Anti-Cardiovascular Disease Compound Library

L5400

Compounds: 1428