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Anti-PDGFB Antibody (MOR-8457) is a specialized CHO-expressed fully human IgG1/λ monoclonal antibody target the human platelet-derived growth factor subunit B, inhibition of ligand-receptor engagement with picomolar affinity across various preclinical experimental models to modulate vascular maturation.

| Description | Anti-PDGFB Antibody (MOR-8457) is a specialized CHO-expressed fully human IgG1/λ monoclonal antibody target the human platelet-derived growth factor subunit B, inhibition of ligand-receptor engagement with picomolar affinity across various preclinical experimental models to modulate vascular maturation. |
| Targets&IC50 | PDGFR:~0.1 nM |
| In vitro | In SPR assays, Anti-PDGFB Antibody (MOR-8457) bound to PDGF-BB with a Kd of 22 pM and inhibited PDGFR-beta phosphorylation with an IC50 of 0.1 nM [1]. |
| Synonyms | MOR-8457 |
| Clone | MOR-8457 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | PDGFB |
| Isotype | IgG4SP-Kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Size | Quantity | Unit Price | Amount | Operation |
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