Dopamine Receptor

Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). Dopamine receptors activate different effectors through not only G-protein coupling, but also signaling through different protein (dopamine receptor-interacting proteins) interactions.

Cat. No.	Product name	CAS No.	Purity
T13463L2	Dihydrexidine hydrochloride	137417-08-4	98%
T13463L2	Dihydrexidine hydrochloride is a full efficacy D1-like dopamine receptor (D1/D5) agonist (IC50: 10 nM for D1 receptor). It also shows potent antiparkinsonian act...
TQ0175	Dexpramipexole	104632-28-2	98%
TQ0175	Dexpramipexole (KNS-760704, R-(+)-Pramipexole) is a neuroprotective agent and weak non-ergoline dopamine agonist.
T13570	Benzamide Derivative 1	108226-05-7	98%
T13570	Benzamide Derivative 1, extracted from patent EP0213775A1 (compound 18), may be useful in the treatment of gastrointestinal disorders.
T15744	Levophacetoperane hydrochloride	23257-56-9	98%
T15744	Levophacetoperane inhibits in vitro in a competitive manner. It also can norepinephrine uptake and dopamine uptake.
T6142	PD128907 HCl	112960-16-4	98%
T6142	PD 128907 HCl is a potent and selective dopamine D3 receptor agonist, with EC50 of 0.64 nM, exhibits 53-fold selectivity over dopamine D2 receptor.
T13898	SPD-473 citrate	161190-26-7	98%
T13898	SPD-473 citrate is an inhibitior of serotonin/dopamine/norepinephrine reuptake.
T3426	Bacoside A	11028-00-5	98%
T3426	Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro. It exerts cytoprotect...
T12252	NRA-0160	204718-47-8	98%
T12252	NRA-0160 is a selective antagonist of dopamine D4 receptor(Ki of 0.48 nM)
T0338	Minaprine	25905-77-5	98%
T0338	Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.
T12606	Quinpirole Hydrochloride	85798-08-9	98%
T12606	Quinpirole Hydrochloride is a high-affinity dopamine D2/D3 receptor agonist.
T15339	Foscarbidopa	1907685-81-7	98%
T15339	Foscarbidopa is a prodrug of Carbidopa. It acts as a dopamine receptor agonist.
T12861L	SB-277011 dihydrochloride	1226917-67-4	98%
T12861L	SB-277011 dihydrochloride is a potent, selective, orally bioavailable and brain penetrate antagonist of dopamine D3 receptor(pKis of 8.0, 6.0, <5.2 and 5.9 for D...
T12676	(Rac)-Rotigotine hydrochloride	102120-99-0	98%
T12676	(Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial the 5-HT1A receptor agonist.
T13245	UCSF924	1434515-70-4	98%
T13245	UCSF924 is a potent and specific agonist of dopamine D4 receptor (DRD4) partial (EC50: 4.2 nM, Ki: 3 nM).
T14088	ABT-670	630119-43-6	98%
T14088	ABT-670 is a selective agonist of dopamine D4 receptor. For human D4, ferret D4, and rat D4, the EC50 values are 89 nM, 160 nM, and 93 nM , respectively.
T1769	Pardoprunox	269718-84-5	98%
T1769	Pardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties. Pardoprunox has been used in trials studying the...
T10837L	Clocapramine	47739-98-0	98%
T10837L	Clocapramine is a D2 and 5-HT2A receptors antagonist.
T10681	Cariprazine D6	T10681	98%
T10681	Cariprazine D6 (RGH-188 D6) is a deuterium-labeled Cariprazine. Cariprazine is an antipsychotic agent (D3 receptors, Ki: 0.085 nM; D2 receptors, Ki: 0.49 nM).
T15100	Desmethyl cariprazine	839712-15-1	98%
T15100	Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (K...
T2S1397	L-Stepholidine	16562-13-3	98%
T2S1397	L-Stepholidine, which has dual actions on dopamine D1 and D2 receptors, attenuates heroin self-administration and cue-induced reinstatement. It also elicits anti...