sars-cov — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T77510	SARS-CoV-2-IN-46		SARS-CoV
	SARS-CoV-2-IN-46 is a SARS-CoV-2 inhibitor.		SARS-CoV
T77516	SARS-CoV-2-IN-39		Antiviral , SARS-CoV
	SARS-CoV-2-IN-39 is a SARS-CoV-2 inhibitor with an EC50 of 1 μM. SARS-CoV-2-IN-39 has antiviral activity and inhibits SARS-CoV-2 by inhibiting SKP2 protein and stabilizing BECN1.		Antiviral , SARS-CoV
T77652	SARS-CoV-2 3CLpro-IN-20		Antiviral , SARS-CoV
	SARS-CoV-2 3CLpro-IN-20 is a covalent SARS-CoV-2 3CLpro inhibitor (IC50s: 0.43 μM,).SARS-CoV-2 3CLpro-IN-20 has potential antiviral activity.		Antiviral , SARS-CoV
T60538	SARS-CoV-2-IN-14	3',5-Dichlorosalicylanilide	SARS-CoV
	SARS-CoV-2-IN-14 is a potent and oral inhibitor of SARS-CoV-2 (IC50:0.39 μM), which is an analogue of niclosamide. SARS-CoV-2-IN-14 was more stable than niclosamide in the determination of human plasma and liver S9 enzym...		SARS-CoV
T9458	PF-00835231		SARS-CoV
	PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively.PF-00835231 is the active compound of the first anti-3CLpro regimen i...		SARS-CoV
TN3651	Cichoriin		Others
	Cichoriin is a photosensitive compound, it could be used as herbal photosensitizing agent in treating benign breast tumor in rats.		Others
T9614	MERS-CoV-IN-1		SARS-CoV
	MERS-CoV-IN-1 exhibits excellent inhibitory activity against coronavirus.It is useful as a pharmaceutical composition for preventing coronavirus-induced diseases (MERS-CoV and SARS).		SARS-CoV
T40207	SARS-CoV-2-IN-7
	SARS-CoV-2-IN-7 demonstrates potent inhibition of viral replication in SARS-CoV-2-infected Vero E6 cells with an IC50 value of 844 nM.
T38942	SARS-CoV-2-IN-9
	SARS-CoV-2-IN-9 is an inhibitor binding to subsites S1 and S2 in SARS-CoV-2 main protease.
T40340	SARS-CoV-2-IN-10
	SARS-CoV-2-IN-10 is a powerful and non-toxic inhibitor of SARS-CoV-2 3CL protease, with IC50 and EC50 values of 0.13 nM and 1.03 nM, respectively. The SARS-CoV-2 3C-like protease (3CLpro) is a critical enzyme for viral r...
T40341	SARS-CoV-2-IN-11
	SARS-CoV-2-IN-11 is a highly potent and non-toxic inhibitor of the 3C-like protease (3CLpro) of SARS-CoV-2, demonstrating IC50 and EC50 values of 0.17 nM and 1.45 nM, respectively. This compound targets the essential vir...
T3S1447	Arteannuin B		SARS-CoV , Ferroptosis
	1. Arteannuin B has potent antimalarial activity.		SARS-CoV , Ferroptosis
T40660	Kansuinine B		IL Receptor , SARS-CoV
	Kansuinine B inhibits Stat3 activation induced by IL-6. Kansuinine B exhibits anti-viral activity and could be used in COVID-19 research.		IL Receptor , SARS-CoV
T12839	SARS-CoV-IN-3		Others
	SARS-CoV-IN-3 is an effective SARS-CoV replication inhibitor.		Others
T12838	SARS-CoV-IN-2		Others
	SARS-CoV-IN-2 is an effective SARS-CoV replication inhibitor		Others
T12837	SARS-CoV-IN-1		Others
	SARS-CoV-IN-1 is an effective SARS-CoV replication inhibitor(EC50 of 4.9 μM in Vero cells).		Others
T36654	Anti-SARS-CoV-2 Spike mAb (CR3022)	Anti-SARS-CoV-2 Spike mAb (CR3022)
	Anti-SARS-CoV-2 Spike mAb (CR3022) is a human monoclonal IgG1 antibody derived from CHO cells. It specifically targets the S1 domain of the Spike protein in both SARS-CoV and SARS-CoV-2.
T9109	SSAA09E2		RAAS , SARS-CoV
	SSAA09E2 is a new SARS-CoV replication inhibitor, acting by blocking early interactions of SARS-S with the receptor for SARS-CoV, Angiotensin Converting Enzyme-2 (ACE2).		RAAS , SARS-CoV
T60919	SARS-CoV-2-IN-13		SARS-CoV
	SARS-CoV-2-IN-13 (compound 5) is an analogue of niclosamide. SARS-CoV-2-IN-13 is more stable than niclosamide in human plasma and liver S9 enzymes assay. SARS-CoV-2-IN-13 can improve bioavailability and half-life when ad...		SARS-CoV
T37174	SARS-CoV MPro-IN-1
	MProinhibitor 11b is an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro; IC50= 0.04 μM in a TR-FRET assay).1It reduces viral yield in the culture supernatant of SARS-CoV-2-in...