T10201 |
PDE IV-IN-1
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PDE
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PDE IV-IN-1 是一种有效的磷酸二酯酶4 (PDE4)抑制剂,具有抗炎活性,可用于治疗哮喘,慢性阻塞性肺病和其他炎症性疾病,是研究抑郁症的潜在化合物。 |
T68191 |
PDE-I2
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PDE-I2 is a parasite schizogony inhibitor. |
T12389 |
PDE-9 inhibitor
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Others
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PDE-9 inhibitor is used for treatment neurodegenerative diseases. |
T5411 |
PDE10-IN-1
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SEP-0372814 |
PDE
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SEP-0372814 是一种高效的 PDE10抑制剂,摘自专利 WO 2013192273 A1。 |
T12395 |
PDE9-IN-1
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PDE
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PDE9-IN-1 是一种选择性和口服生物可利用的 PDE9A 抑制剂(IC50 为 8.7 nM)。 |
T36832 |
PDE4B-IN-2
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A 33 |
PDE
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PDE4B-IN-2 是一种具有口服活性,选择性 PDE4B 抑制剂,IC50 为 15 nM。PDE4B-IN-2 抑制 PDE4D (IC50=1.7 µM)。PDE4B-IN-2 表现出有效的抗炎作用。 |
T8659 |
K-Ras-PDEδ-IN-1
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PDE
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K-Ras-PDEδ-IN-1 是新型的 K-Ras-PDEδ 抑制剂,它能够以低纳摩尔Kd8 nM 与 PDEδ 的法尼基结合袋竞争性结合。 |
T28352 |
PDE9-IN-(S)-C33
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(S)-C33 |
PDE
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PDE9-IN-(S)-C33 是一种有效的选择性 PDE9 抑制剂 (IC50 = 11 nM)。 PDE9-IN-(S)-C33 可用于中枢神经系统疾病和糖尿病的相关研究。 |
T18529 |
PDEC-NB
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4-Nitrophenyl 2-(Pyridin-2-Yldisulfanyl)Ethyl Carbonate |
Others
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PDEC-NB 是用于抗体-药物偶联物的二硫键可切割接头。 |
T12391 |
PDE1-IN-3
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Others
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PDE1-IN-3 is a selective inhibitor of human phosphodiesterase 1 (PDE1). |
T12392 |
PDE12-IN-3
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Others
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PDE12-IN-3 is an inhibitor of phosphodiesterase 12 (PDE12) (pXC50 of 7.68),with antiviral activity. |
T12390 |
PDE1-IN-2
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Others
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PDE1-IN-2 is an PDE1 inhibitor(PDE1C, PDE1B and PDE1A with IC50 values of 6, 140 and 164 nM, respectvely). |
T12394 |
PDE5-IN-2
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PDE
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PDE5-IN-2 is a potent, highly selective, and orally active inhibitor of PDE5(IC50 of 0.31 nM) |
T10028 |
PDE4 inhibitor intermediate 1
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Others
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PDE4 inhibitor intermediate 1 is a PDE4 inhibitor synthesis intermediate. |
T12393 |
PDE2/PDE10-IN-1
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Others
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PDE2/PDE10-IN-1 is a inhibitor of phosphodiesterase 2 (PDE2) and PDE10(IC50s of 29 and 480 nM, respectively). |
T39796 |
PDE12-IN-1
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PDE12-IN-1 |
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PDE12-IN-1 is a powerful and specific inhibitor of PDE12, exhibiting a pIC 50 value of 9.1 for enzyme inhibition. It eff... |
T24605 |
PDE5-IN-6c
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PDE5IN6c,PDE5 inhibitor 6c |
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PDE5-IN-6c is a potent and selective inhibitor of PDE5A1. |
T24606 |
PDE7 inhibitor S14
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S14,PDE7 inhibitor-S14 |
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PDE7 inhibitor S14 is a cell-permeable PDE7 inhibitor that acts by targeting the cyclic adenosine monophosphate (cAMP)/c... |
T40356 |
PDE4-IN-3
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PDE4-IN-3 |
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PDE4-IN-3 is a newly developed oral compound that acts as a potent inhibitor of the enzyme phosphodiesterase 4 (PDE4), d... |
T40278 |
PDE2A-IN-1
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PDE2A-IN-1 |
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PDE2A-IN-1 is a phosphodiesterase 2A (PDE2A) inhibitor with an IC 50 value of 1.3 nM. |