Search Result

Search Results for "pde"

Targets

Compounds

Cat No.	Product Name
T10201	PDE IV-IN-1		PDE
	PDE IV-IN-1 是一种有效的磷酸二酯酶4 (PDE4)抑制剂，具有抗炎活性，可用于治疗哮喘，慢性阻塞性肺病和其他炎症性疾病，是研究抑郁症的潜在化合物。		PDE
T68191	PDE-I2
	PDE-I2 is a parasite schizogony inhibitor.
T12389	PDE-9 inhibitor		Others
	PDE-9 inhibitor is used for treatment neurodegenerative diseases.		Others
T5411	PDE10-IN-1	SEP-0372814	PDE
	SEP-0372814 是一种高效的 PDE10抑制剂，摘自专利 WO 2013192273 A1。		PDE
T12395	PDE9-IN-1		PDE
	PDE9-IN-1 是一种选择性和口服生物可利用的 PDE9A 抑制剂（IC50 为 8.7 nM）。		PDE
T36832	PDE4B-IN-2	A 33	PDE
	PDE4B-IN-2 是一种具有口服活性，选择性 PDE4B 抑制剂，IC50 为 15 nM。PDE4B-IN-2 抑制 PDE4D (IC50=1.7 µM)。PDE4B-IN-2 表现出有效的抗炎作用。		PDE
T8659	K-Ras-PDEδ-IN-1		PDE
	K-Ras-PDEδ-IN-1 是新型的 K-Ras-PDEδ 抑制剂，它能够以低纳摩尔Kd8 nM 与 PDEδ 的法尼基结合袋竞争性结合。		PDE
T28352	PDE9-IN-(S)-C33	(S)-C33	PDE
	PDE9-IN-(S)-C33 是一种有效的选择性 PDE9 抑制剂 (IC50 = 11 nM)。 PDE9-IN-(S)-C33 可用于中枢神经系统疾病和糖尿病的相关研究。		PDE
T18529	PDEC-NB	4-Nitrophenyl 2-(Pyridin-2-Yldisulfanyl)Ethyl Carbonate	Others
	PDEC-NB 是用于抗体-药物偶联物的二硫键可切割接头。		Others
T12391	PDE1-IN-3		Others
	PDE1-IN-3 is a selective inhibitor of human phosphodiesterase 1 (PDE1).		Others
T12392	PDE12-IN-3		Others
	PDE12-IN-3 is an inhibitor of phosphodiesterase 12 (PDE12) (pXC50 of 7.68),with antiviral activity.		Others
T12390	PDE1-IN-2		Others
	PDE1-IN-2 is an PDE1 inhibitor(PDE1C, PDE1B and PDE1A with IC50 values of 6, 140 and 164 nM, respectvely).		Others
T12394	PDE5-IN-2		PDE
	PDE5-IN-2 is a potent, highly selective, and orally active inhibitor of PDE5(IC50 of 0.31 nM)		PDE
T10028	PDE4 inhibitor intermediate 1		Others
	PDE4 inhibitor intermediate 1 is a PDE4 inhibitor synthesis intermediate.		Others
T12393	PDE2/PDE10-IN-1		Others
	PDE2/PDE10-IN-1 is a inhibitor of phosphodiesterase 2 (PDE2) and PDE10(IC50s of 29 and 480 nM, respectively).		Others
T39796	PDE12-IN-1	PDE12-IN-1
	PDE12-IN-1 is a powerful and specific inhibitor of PDE12, exhibiting a pIC 50 value of 9.1 for enzyme inhibition. It eff...
T24605	PDE5-IN-6c	PDE5IN6c,PDE5 inhibitor 6c
	PDE5-IN-6c is a potent and selective inhibitor of PDE5A1.
T24606	PDE7 inhibitor S14	S14,PDE7 inhibitor-S14
	PDE7 inhibitor S14 is a cell-permeable PDE7 inhibitor that acts by targeting the cyclic adenosine monophosphate (cAMP)/c...
T40356	PDE4-IN-3	PDE4-IN-3
	PDE4-IN-3 is a newly developed oral compound that acts as a potent inhibitor of the enzyme phosphodiesterase 4 (PDE4), d...
T40278	PDE2A-IN-1	PDE2A-IN-1
	PDE2A-IN-1 is a phosphodiesterase 2A (PDE2A) inhibitor with an IC 50 value of 1.3 nM.