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Search Results for " pde "

Targets

202

Compounds

23

Natural Products

10

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T10201 PDE IV-IN-1 PDE
PDE IV-IN-1 is a potent phosphodiesterase 4 (PDE4) inhibitor with anti-inflammatory activity for the treatment of asthma, chronic obstructive pulmonary disease and other inflammatory diseases, and is a potential compound...
T68191 PDE-I2
PDE-I2 is a parasite schizogony inhibitor.
T12389 PDE-9 inhibitor Others
PDE-9 inhibitor is used for treatment neurodegenerative diseases.
T21965 MBCQ PDE
MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.
T5411 PDE10-IN-1 SEP-0372814 PDE
PDE10-IN-1 (SEP-0372814) is used for treating CNS and metabolic disorders.
T6462 Deltarasin PDE , Ras
Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.
T6054 GSK256066 PDE
GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380, 000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7.Phase 2.
T12395 PDE9-IN-1 PDE
PDE9-IN-1 is a selective and orally bioavailable Inhibitor of PDE9A(IC50 of 8.7 nM).
T2129 Zaprinast PDE
Zaprinast is a cGMP-selective phosphodiesterase (PDE) inhibitor and a GPR35 agonist. It has a strong activating effect on rat GPR35 and a certain activating effect on human GPR35. It reduces vascular remodeling through a...
T10676 Carbodenafil PDE
Carbodenafil is a Sildenafil related compound found in healthy foods. Sildenafil is a PDE5 inhibitor (IC50: 5.22 nM).
T4695 CP671305 PDE
CP671305 is an orally active, potent and selective inhibitor of phosphodiesterase-4-D.
T7888 Enpp-1-IN-1 PDE
Enpp-1-IN-1 is an inhibitor of Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1)
T3631 PF-8380 PDE
PF-8380 is an effective and orally available autotaxin inhibitor (IC50: 2.8 nM, in isolated enzyme assay; 101 nM, in the human whole blood). It modulates lysophosphatidic acid (LPA) levels in vivo/vitro by directly inhib...
T4462 Roflumilast N-oxide PDE
Roflumilast N-oxide is an inhibitor of PDE type 4.
T10410 ATX inhibitor 1 PDE
ATX inhibitor 1 is a potent ATX inhibitor (IC50: 1.23 nM, FS-3 and 2.18 nM, bis-pNPP).
T1618 Dipyridamole Persantin,Dypyridamole,Dipyridamol,NSC-515776,Dipyudamine PDE
Dipyridamole (Persantin) is a Platelet Aggregation Inhibitor. The physiologic effect of dipyridamole is by means of Decreased Platelet Aggregation.
T12267 NSP-805 PDE
NSP-805 is a potent and selective guinea pig cardiac phosphodiesterase 3 (PDE3) inhibitor.
T5106 BRL-50481 PDE
BRL-50481 is a novel and selective inhibitor of PDE7 with IC50s of 0.15, 12.1, 62 and 490 μM for PDE7A, PDE7B, PDE4 and PDE3, respectively.
T2646 HA130 PDE
HA130 is a selective ATX (autotaxin) inhibitor.
T13448 (R)-(-)-Rolipram (R)-Rolipram,(-)-Rolipram DNA-PK , Others
(R)-(-)-Rolipram ((-)-Rolipram) is an R-enantiomer of Rolipram which is a PDE4 inhibitor.
T12150 N-Methylbenzamide PDE
N-Methylbenzamide is a potent phosphodiesterase 10A (PDE10A) inhibitor,with anti-cancer activity.
T5474 D159687 D 159687 PDE
D159687 is a selective PDE4D inhibitor,had a procognitive profile as it improved memory in the novel object recognition test but had no antidepressant or anxiolytic benefit.
T7346 Lodenafil Hydroxyhomosildenafil PDE
Lodenafil (Hydroxyhomosildenafil) is a potent PDE5 inhibitor, with treatment of erectile dysfunction (ED)
T4041 Ziritaxestat GLPG1690 PDE
Ziritaxestat (GLPG1690), an autotaxin inhibitor, currently being evaluated in an exploratory phase 2 study in idiopathic pulmonary fibrosis patients.
T27172 Difamilast PDE
Difamilast is an inhibitor of phosphodiesterase IV.
T8515 Osoresnontrine BI-409306 PDE
Osoresnontrine is a potent and selective inhibitor of PDE9A (IC50 of 52 nM),and can be used in the research of memory.
T12913 Siguazodan SKF 94836 PDE
Siguazodan (SKF 94836) is an effective, selective, orally active phosphodiesterase III ((PDE-III)) inhibitor with an IC50 of 117 nM. Siguazodan inhibited phenylephrine induced 5-HT release with an IC50 value of 4.2 μM。 S...
T1096 Milrinone Win 47203 PDE
Milrinone (Win 47203) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of milrinone is as a Phosphodiesterase 3 Inhibitor.
T8405 Vardenafil hydrochloride PDE
Vardenafil hydrochloride is a New Phosphodiesterase Type 5(PDE5) Inhibitor, in the Treatment of Erectile Dysfunction in Men With Diabetes
T6548 Irsogladine Dicloguamine PDE , AChR
Irsogladine (Dicloguamine) is an anti-gastric ulcer agent that facilitates gap-junctional intercellular communication through M1 muscarininc acetylcholine receptor binding.
T10590 Zatolmilast BPN14770 Others , PDE
Zatolmilast (BPN14770) is an allosteric inhibitor of selective phosphodiesterase 4D (PDE4D; IC50s: 7.8 nM and 7.4 nM for PDE4D7 and PDE4D3).
T23154 Piclamilast RPR 73401,RP 73401 PDE
Piclamilast (RP 73401) is a PDE4 inhibitor.
T6147 Nortadalafil Demethyl Tadalafil PDE
Nortadalafil (Demethyl Tadalafil) is demethyl Tadalafil, which is a PDE5 inhibitor, treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.
T16499 Mardepodect PF-2545920 PDE
Mardepodect (PF-2545920) is a phosphodiesterase inhibitor selective for the PDE10A subtype with an IC50 of 0.37 nM, >1000-fold selectivity over PDE. It is potentially useful for the treatment of schizophrenia. Phosphodie...
T36832 PDE4B-IN-2 A 33 PDE
PDE4B-IN-2 (A 33) is an orally active and selective PDE4B inhibitor with an IC50 of 15 nM. PDE4B-IN-2 inhibits PDE4D (IC50=1.7 µM). PDE4B-IN-2 exhibits potent anti-inflammatory effects.
T21865 BC 11-38 PDE
BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).
T8919 Homo Sildenafil PDE
Homo Sildenafil is an analog of Sildenafil, It acts as a phosphodiesterase inhibitor.
T8659 K-Ras-PDEδ-IN-1 PDE
K-Ras-PDEδ-IN-1 is a potent inhibitor of competitive K-Ras-PDEδ.It binds to the farnesyl binding pocket of PDEδ(Kd of 8 nM).
T7542 Amino Tadalafil PDE
Amino tadalafil is a potent phosphodiesterase 5 (PDE5) inhibitor.
T8506 THPP-1 PDE
THPP-1 is a potent and orally bioavailable inhibitor of PDE10A(Ki of 1 nM and 1.3 nM for human and rat PDE10A, respectively).
T5033 Olprinone Loprinone PDE
Olprinone (Loprinone)(Loprinone) is a selective phosphodiesterase 3 (PDE3) inhibitor.Olprinone has been reported to improve microcirculation and attenuate inflammation. Olprinone is often used to increase cardiac output ...
T11689 ITI-214 ITI214 PDE
ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = ...
T5101 BW-A 78U BW-A78U PDE
BW-A 78U is a PDE4 inhibitor (IC50: 3 μM). It is not inhibition on the lipopolysaccharide (LPS)-induced TNF-α release.
T9805 BAY 2666605 PDE
BAY 2666605 is an orally active inhibitor of PDE3A and PDE3B with IC50s of 87 nM and 50 nM, respectively. BAY 2666605 has anticancer effects.
T1745 Balipodect TAK063,TAK-063,TAK 063 PDE
Balipodect (TAK063) is a highly effective and selective PDE10A inhibitor (IC50: 0.30 nM); Its selectivity is >15000-fold over other PDEs.
T15381 Gisadenafil UK-369003 PDE
Gisadenafil (UK-369003) is a selective inhibitor of phosphodiesterase 5 (PDE5) with an IC50 of 3.6 nM and prevents degradation of cGMP.
T5956 VP3.15 dihydrobromide GSK-3 , PDE
VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE7- glycogen synthase kinase (GSK)3 inhibitor(with IC50s of 1.59 μM , 0.88 μM,respectively.)
T7642 Cilostamide OPC3689 PDE
Cilostamide (OPC3689) is a selective phosphodiesterase (PDE)3A and PDE3B inhibitor(IC50 values of 27 and 50 nM, respectively)
T9816 Arofylline LAS 31025 PDE
Arofylline (LAS 31025) is a PDE4 inhibitor and can be used for asthma studies.
T2137 Ibudilast AV-411,KC-404,MN-166 PDE
Ibudilast (MN-166)(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor. It is approved for use as an anti-inflammatory in Japan.

Compounds

PDE IV-IN-1
T10201
Synonym:
Target: PDE
PDE-I2
T68191
Synonym:
Target:
PDE-9 inhibitor
T12389
Synonym:
Target: Others
MBCQ
T21965
Synonym:
Target: PDE
PDE10-IN-1
T5411
Synonym: SEP-0372814
Target: PDE
Deltarasin
T6462
Synonym:
Target: PDE, Ras
GSK256066
T6054
Synonym:
Target: PDE
PDE9-IN-1
T12395
Synonym:
Target: PDE
Zaprinast
T2129
Synonym:
Target: PDE
Carbodenafil
T10676
Synonym:
Target: PDE
CP671305
T4695
Synonym:
Target: PDE
Enpp-1-IN-1
T7888
Synonym:
Target: PDE
PF-8380
T3631
Synonym:
Target: PDE
Roflumilast N-oxide
T4462
Synonym:
Target: PDE
ATX inhibitor 1
T10410
Synonym:
Target: PDE
Dipyridamole
T1618
Synonym: Persantin,Dypyridamole,Dipyridamol,NSC-515776,Dipyudamine
Target: PDE
NSP-805
T12267
Synonym:
Target: PDE
BRL-50481
T5106
Synonym:
Target: PDE
HA130
T2646
Synonym:
Target: PDE
(R)-(-)-Rolipram
T13448
Synonym: (R)-Rolipram,(-)-Rolipram
Target: DNA-PK, Others
N-Methylbenzamide
T12150
Synonym:
Target: PDE
D159687
T5474
Synonym: D 159687
Target: PDE
Lodenafil
T7346
Synonym: Hydroxyhomosildenafil
Target: PDE
Ziritaxestat
T4041
Synonym: GLPG1690
Target: PDE
Difamilast
T27172
Synonym:
Target: PDE
Osoresnontrine
T8515
Synonym: BI-409306
Target: PDE
Siguazodan
T12913
Synonym: SKF 94836
Target: PDE
Milrinone
T1096
Synonym: Win 47203
Target: PDE
Vardenafil hydrochloride
T8405
Synonym:
Target: PDE
Irsogladine
T6548
Synonym: Dicloguamine
Target: PDE, AChR
Zatolmilast
T10590
Synonym: BPN14770
Target: Others, PDE
Piclamilast
T23154
Synonym: RPR 73401,RP 73401
Target: PDE
Nortadalafil
T6147
Synonym: Demethyl Tadalafil
Target: PDE
Mardepodect
T16499
Synonym: PF-2545920
Target: PDE
PDE4B-IN-2
T36832
Synonym: A 33
Target: PDE
BC 11-38
T21865
Synonym:
Target: PDE
Homo Sildenafil
T8919
Synonym:
Target: PDE
K-Ras-PDEδ-IN-1
T8659
Synonym:
Target: PDE
Amino Tadalafil
T7542
Synonym:
Target: PDE
THPP-1
T8506
Synonym:
Target: PDE
Olprinone
T5033
Synonym: Loprinone
Target: PDE
ITI-214
T11689
Synonym: ITI214
Target: PDE
BW-A 78U
T5101
Synonym: BW-A78U
Target: PDE
BAY 2666605
T9805
Synonym:
Target: PDE
Balipodect
T1745
Synonym: TAK063,TAK-063,TAK 063
Target: PDE
Gisadenafil
T15381
Synonym: UK-369003
Target: PDE
VP3.15 dihydrobromide
T5956
Synonym:
Target: GSK-3, PDE
Cilostamide
T7642
Synonym: OPC3689
Target: PDE
Arofylline
T9816
Synonym: LAS 31025
Target: PDE
Ibudilast
T2137
Synonym: AV-411,KC-404,MN-166
Target: PDE
1 2 3 4 5
Cat No. Product Name Synonyms Targets
TN1266 3-O-Methylquercetin IL Receptor , cAMP , PDE
3-O-Methylquercetin is a selective and competitive PDE3/PDE4 inhibitor, and inhibits PDE3 than PDE4 with a low K(m) value; it inhibits total cAMP- and cGMP-phosphodiesterase (PDE) of guinea pig trachealis at low concentr...
T8787 Drotaverine hydrochloride PDE
Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor,and is an antispasmodic drug, used to enhance cervical dilation during childbirth. Drotaverine hydrochloride is structurally rela...
T1681 Aminophylline Phyllocontin PDE , Adenosine Receptor
Aminophylline (Phyllocontin) is a competitive nonselective phosphodiesterase inhibitor giving a bronchodilatory effect.
TN1416 Ayanin IL Receptor , P450 , PARP , PDE
Ayanin has vasorelaxant activity, it also may have the potential for use in treating allergic asthma.The IC(50) value of Ayanin (quercetin-3,7,4'-O-trimethylether) is 2.2microM for inhibiting interleukin (IL)-4 productio...
T7027 EURYCOMANONE Pasakbumin A Others
Eurycomanone (Pasakbumin A) is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2.Eurycomanone has anti-cancer activity, inhibits A549 lung cancer cell p...
T0892 Diphylline Dyphylline,Diprophylline PDE , Adenosine Receptor
Diphylline (Diprophylline) is a xanthine derivative. Diphylline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Diphylline probably acts as a competitive inhibitor of phosphodies...
T2855 Icariin Ieariline PDE , PPAR , Autophagy
Icariin (Ieariline) is a flavonol glycoside, inhibiting PDE5 and PDE4 activities. Icariin also is a PPARα activator.
T3783 Fraxin Fraxoside,Fraxetin-8-O-glucoside,Paviin OAT , transporter , PDE
Fraxin (Fraxoside) is a glucoside of fraxetin.
T0480 Doxofylline Doxophylline PDE , Adenosine Receptor
Doxofylline (Doxophylline) is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with s...
TN2159 Robustine PDE
Robustine is a natural product, exhibits inhibitory potency against human phosphodiesterase 5 (hPDE5A) in vitro.
T1083 Theophylline Theo-24,1,3-Dimethylxanthine Endogenous Metabolite , HDAC , PDE , Adenosine Receptor , Autophagy
Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3...
T6427 Butein 2’,3,4,4’-tetrahydroxy Chalcone Apoptosis , EGFR , Others , PDE , Autophagy
Butein (2’,3,4,4’-tetrahydroxy Chalcone), a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR.
T2205 Acefylline Theophylline-7-acetic acid,Carboxymethyltheophylline,acetyloxytheophylline,Theophyllineacetic acid TNF , PAD , PKA , HDAC , PDE , Adenosine Receptor
Acefylline (Theophylline-7-acetic acid), a stimulant drug of the xanthine chemical class, acts as an adenosine receptor antagonist. It is combined with diphenhydramine in the pharmaceutical preparation Etanautine to help...
T0167 Vinpocetine RGH-4405,Ethyl apovincaminate IκB/IKK , NF-κB , Sodium Channel , PDE
Vinpocetine (RGH-4405) is a selective inhibitor of cyclic GMP phosphodiesterase (PDE).
T5S2059 Glaucine Calcium Channel , Dopamine Receptor , Influenza Virus , Adrenergic Receptor , PDE
Glaucine has antitussive, antioxidative potential and antiviral activities, it may be an anti-arthritic agent, it can enhance LPS and zymosan-induced IL-10 production. Glaucine can inhibit the migration and invasion of h...
T0070 Pentoxifylline Oxpentifylline,PTX,BL-191 HIV Protease , PDE , Adenosine Receptor , Autophagy
Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It also inhibits platelet ...
T17199 Udenafil PDE
Udenafil is an inhibitor of PDE5 .
TN2217 Sophoflavescenol Others , Beta-Secretase , BACE , PDE , AChR , AChE
Sophoflavescenol is a mixed inhibitor of PDE5 with a K(i) value of 0.005 microM. Sophoflavescenol has antioxidant, anti-inflammatory, and apoptotic effects , these effects might contribute to the antitumor activity witho...
T5940 Proxyphylline 7-(2-Hydroxypropyl)theophylline PDE , Adenosine Receptor
Proxyphylline (7-(2-Hydroxypropyl)theophylline) is a dual of adenosine A1/A2a receptor inhibitor and phosphodiesterase (PDE) inhibitor. Proxyphylline acts as a cardiac stimulant, vasodilator and bronchodilator.
TN2974 3-O-Methylquercetin tetraacetate IL Receptor , TNF , PDE
Quercetin 3-O-methyl ether is a potent phosphodiesterase (PDE)3/4 inhibitor, it has potential for treating asthma against ovalbumin-induced airway hyperresponsiveness.
TN4317 Isopedicin NADPH-oxidase , cAMP , p38 MAPK , PKA , JNK , PDE
Isopedicin has anti-inflammatory functions, it inhibits the O(2)(*)(-) production in human neutrophils by an elevation of cellular cAMP and activation of PKA through its inhibition of cAMP-specific PDE.
TN4398 Kushenol B Others
Kushenol B is a natural product for research related to life sciences. The catalog number is TN4398 and the CAS number is 99217-64-8.
T16397 Ophiobolin A Others
Ophiobolin A is a fungal metabolite and a phytotoxin and is an effective and irreversibly inhibitor of calmodulin-activated cyclic nucleotide phosphodiesterase (IC50: 9 μM). Ophiobolin A also has antimicrobial and antica...

Natural Products

3-O-Methylquercetin
TN1266
Synonym:
Target: IL Receptor, cAMP, PDE
Drotaverine hydrochloride
T8787
Synonym:
Target: PDE
Aminophylline
T1681
Synonym: Phyllocontin
Target: PDE, Adenosine Receptor
Ayanin
TN1416
Synonym:
Target: IL Receptor, P450, PARP, PDE
EURYCOMANONE
T7027
Synonym: Pasakbumin A
Target: Others
Diphylline
T0892
Synonym: Dyphylline,Diprophylline
Target: PDE, Adenosine Receptor
Icariin
T2855
Synonym: Ieariline
Target: PDE, PPAR, Autophagy
Fraxin
T3783
Synonym: Fraxoside,Fraxetin-8-O-glucoside,Paviin
Target: OAT, transporter, PDE
Doxofylline
T0480
Synonym: Doxophylline
Target: PDE, Adenosine Receptor
Robustine
TN2159
Synonym:
Target: PDE
Theophylline
T1083
Synonym: Theo-24,1,3-Dimethylxanthine
Target: Endogenous Metabolite, HDAC, PDE, Adenosine Receptor, Autophagy
Butein
T6427
Synonym: 2’,3,4,4’-tetrahydroxy Chalcone
Target: Apoptosis, EGFR, Others, PDE, Autophagy
Acefylline
T2205
Synonym: Theophylline-7-acetic acid,Carboxymethyltheophylline,acetyloxytheophylline,Theophyllineacetic acid
Target: TNF, PAD, PKA, HDAC, PDE, Adenosine Receptor
Vinpocetine
T0167
Synonym: RGH-4405,Ethyl apovincaminate
Target: IκB/IKK, NF-κB, Sodium Channel, PDE
Glaucine
T5S2059
Synonym:
Target: Calcium Channel, Dopamine Receptor, Influenza Virus, Adrenergic Receptor, PDE
Pentoxifylline
T0070
Synonym: Oxpentifylline,PTX,BL-191
Target: HIV Protease, PDE, Adenosine Receptor, Autophagy
Udenafil
T17199
Synonym:
Target: PDE
Sophoflavescenol
TN2217
Synonym:
Target: Others, Beta-Secretase, BACE, PDE, AChR, AChE
Proxyphylline
T5940
Synonym: 7-(2-Hydroxypropyl)theophylline
Target: PDE, Adenosine Receptor
3-O-Methylquercetin tetraacetate
TN2974
Synonym:
Target: IL Receptor, TNF, PDE
Isopedicin
TN4317
Synonym:
Target: NADPH-oxidase, cAMP, p38 MAPK, PKA, JNK, PDE
Kushenol B
TN4398
Synonym:
Target: Others
Ophiobolin A
T16397
Synonym:
Target: Others

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02081 PDE2A Protein, Human, Recombinant (aa 215-900, His) Human Baculovirus-Insect Cells
cGMP-dependent 3',5'-cyclic phosphodiesterase, also known as cyclic GMP-stimulated phosphodiesterase and PDE2A, is a peripheral membrane protein that belongs to the cyclic nucleotide phosphodiesterase family and PDE2 sub...
TMPY-01588 ALDH7A1 Protein, Human, Recombinant (His) Human E. coli
ALDH7A1 (Aldehyde dehydrogenase 7 family, member A1) is a member of subfamily 7 in the aldehyde dehydrogenase family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol...
TMPY-01819 PDE1B Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, also known as Cam-PDE 1B and PDE1B, is a cytoplasm protein that belongs to the cyclic nucleotide phosphodiesterase family and PDE1 subfamily. Pho...
TMPY-01922 PDE9A Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, also known as PDE9A, is a member of the cyclic nucleotide phosphodiesterase family and PDE9 subfamily. PDE9A is expressed in all tissues examined (testis, br...
TMPY-01921 PDE9A Protein, Human, Recombinant (His) Human E. coli
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, also known as PDE9A, is a member of the cyclic nucleotide phosphodiesterase family and PDE9 subfamily. PDE9A is expressed in all tissues examined (testis, br...
TMPH-02575 PDE5A Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in t...
TMPH-03254 PDE1C Protein, Rat, Recombinant (His) Rat E. coli
Inhibits a wide variety of beta lactamases.
TMPH-01467 PDE9A Protein, Human, Recombinant (His & Myc) Human E. coli
Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Necessary for the ...
TMPY-02977 PDE1C Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
PDE1C belongs to the cyclic nucleotide phosphodiesterase family, PDE1 subfamily. Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds ...
TMPH-02706 PDE9A Protein, Mouse, Recombinant (His) Mouse E. coli
Required for extrapulmonary dissemination. Mediates adherence to epithelial cells by binding to sulfated glycoconjugates present at the surface of these cells.
TargetMol