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Verofylline

Name: Verofylline
Brand: TargetMol
SKU: T35048
Price: 146 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T35048Cas No. 66172-75-6

Alias Verofyllinum, Verofilina, CK-0383, CK0383, CK 0383

Verofylline (Verofyllinum) is an orally available, long-acting, multiacting, methylxanthine-substituted bronchodilator with inhibitory effects on PDE4 for the treatment of asthma disease research obesity.

Verofylline

🥰Excellent

Purity: 99.78%

Catalog No. T35048Alias Verofyllinum, Verofilina, CK-0383, CK0383, CK 0383Cas No. 66172-75-6

Pack Size	Price	Availability
1 mg	$146	In Stock
5 mg	$350	In Stock
10 mg	$530	In Stock
25 mg	$859	In Stock
50 mg	$1,180	In Stock
100 mg	$1,590	In Stock
500 mg	$3,190	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.78%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Verofylline (Verofyllinum) is an orally available, long-acting, multiacting, methylxanthine-substituted bronchodilator with inhibitory effects on PDE4 for the treatment of asthma disease research obesity.
Synonyms	Verofyllinum, Verofilina, CK-0383, CK0383, CK 0383

Chemical Properties

Molecular Weight	250.3
Formula	C₁₂H₁₈N₄O₂
Cas No.	66172-75-6
Smiles	C(C(CC)C)N1C2=C(C(=O)N(C)C1=O)NC(C)=N2
Relative Density.	1.31g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (239.71 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9952 mL	19.9760 mL	39.9521 mL	199.7603 mL
5 mM	0.7990 mL	3.9952 mL	7.9904 mL	39.9521 mL
10 mM	0.3995 mL	1.9976 mL	3.9952 mL	19.9760 mL
20 mM	0.1998 mL	0.9988 mL	1.9976 mL	9.9880 mL
50 mM	0.0799 mL	0.3995 mL	0.7990 mL	3.9952 mL
100 mM	0.0400 mL	0.1998 mL	0.3995 mL	1.9976 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc