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  • Dehydrogenase
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Results for "

dehydrogenase

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    684
    TargetMol | Inhibitors_Agonists
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    1
    TargetMol | Compound_Libraries
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    13
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    TargetMol | Inhibitors_Agonists
Glycyrrhizic acid
Glycyrrhizin
T27411405-86-3
Glycyrrhizic acid (Glycyrrhizin) is a triterpenoid saponinl with anti-tumor and anti-diabetic activities.
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3-Nitropropanoic acid
β-Nitropropionic acid, Bovinocidin, 3-NP acid, 3-NP
T3009504-88-1
3-Nitropropanoic acid (Bovinocidin) is an irreversible inhibitor of succinate dehydrogenase.
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sodium dichloroacetate
Sodium Dichloroacetate, Sodium dichloroacetate (DCA), Sodium bichloroacetic acid, DCA sodium salt
T36042156-56-1
Sodium dichloroacetate (BCA) , a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion channel axis, trigger apoptosis in cancer cells, and inhibit tumor growth.
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Dihydrouracil
5,6-Dihydrouracil
T4886504-07-4
5,6-Dihydrouracil (5,6-Dihydrouracil) is an intermediate breakdown product of uracil.
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Glucose-6-phosphate dehydrogenase
G6PDH, G6PD
T738969001-40-5
Glucose-6-phosphate dehydrogenase is a rate-controlling enzyme of the pentose phosphate pathway (PPP) that catalyzes the oxidative dehydrogenation of glucose-6-phosphate to produce glucose-6-phosphate and NADPH.It is a sex-linked metabolic enzyme involved in the shunting of hexose monophosphate.
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Rotenone
Rotocide, Rotenon, Paraderil, Dactinol, Barbasco
T297083-79-4
Rotenone (Rotocide) is a natural product and a botanical insecticide. Rotenone is a mitochondrial electron transport complex I inhibitor that promotes the production of reactive oxygen species in mitochondria and induces apoptosis.
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Methylmalonic acid
NSC 25201, MMA, Methylpropanedioic acid, Methylmalonate, Isosuccinic acid
T4817516-05-2
Methylmalonic acid is an indicator of vitamin B-12 deficiency in cancer patients.Methylmalonic acid is a competitive succinate dehydrogenase inhibitor.
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Diethanolamine hydrochloride
TN940914426-21-2
Diethanolamine hydrochloride has a variety of biological activities and is an inhibitor of HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4) and pregnane X receptor (PXR), as well as an agonist of p53 and an antagonist of Estrogen receptor.
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    Citric acid trilithium salt tetrahydrate
    Trilithium citrate tetrahydrate, Lithium citrate tribasic tetrahydrate
    T02566080-58-6
    Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy of psychiatric disease. It has shown the effects of signaling pathways and metabolic in the brain based on the particular disease and clinical condition model. According to the reports, Citric acid trilithium salt tetrahydrate was used as a mood stabilizer when treating bipolar mood disorders (BD) and lower the risk of self-harm in BD patient. In addition,Citric acid trilithium salt tetrahydrate has been the choice drug in the therapy of acute manic episodes.Citric acid trilithium salt tetrahydrate also could dissolve uric acid crystals in urine achieved from patients with gout. Besides,Citric acid trilithium salt tetrahydrate have some dose-dependent side-effects. The the main side-effects of Lithium Citrate is the tendency to inhibit the prostatic acid phosphatase enzyme (PAP), which result in the accumulation of PAP.
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    D-Mannitol
    Osmitrol, Mannitol, Mannite
    T041469-65-8
    D-Mannitol (Mannitol) is a diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. D-Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.
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    Orotic acid
    Vitamin B13, 6-Carboxyuracil
    T074665-86-1
    Orotic acid (Vitamin B13) is an intermediate product in pyrimidine metabolism.
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    Daidzin
    NPI-031D, Daidzoside, Daidzein 7-O-glucoside, Daidzein 7-glucoside
    T2901552-66-9
    Daidzin (Daidzoside) is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities.
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    alpha-Mangostin
    α-Mangostin, Mangostin
    T17176147-11-1
    alpha-Mangostin (Mangostin) is a natural xanthonoid, a type of organic compound isolated from various parts of the mangosteen tree.
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    Prunetin
    Prunusetin
    T4S0878552-59-0
    1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin mediates anti-obesity adipogenesis effects by suppressing obesity-related transcription through a feedback mechanism that regulates the expression of adiponectin, adipoR1, adipoR2, and AMPK. 3. Prunetin and biochanin A are potent reducers of NF-κB and ERK activation, zonula occludens 1 tyrosine phosphorylation, and metalloproteinase-mediated shedding activity, which may account for the barrier-improving ability of these isoflavones. 4. Prunetin significantly suppresses ATP-induced mucin secretion from cultured RTSE cells; Prunetin inhibits the production of MUC5AC mucin protein induced by EGF or PMA from NCI-H292 cells; Prunetin also inhibits the expression of MUC5AC mucin gene induced by EGF or PMA from NCI-H292 cells.
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    11Beta-hydroxyprogesterone
    11β-Hydroxyprogesterone
    TCA2511600-57-7
    11Beta-hydroxyprogesterone (11β-Hydroxyprogesterone) is an inhibitor of 11beta-hydroxysteroid dehydrogenase (11betaHSD) type 2, which activates the human hydrocorticosteroid receptor in COS-7 cells, and may be useful in the study of metabolism-related diseases.
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    7-10 days
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    Taraxerone
    TJS1382514-07-8
    Taraxerone has allelopathic and antifungal effects.Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration with the concentration dependent manner.
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    18β-Glycyrrhetinic acid
    Glycyrrhetin, Enoxolone
    T0036471-53-4
    18β-Glycyrrhetinic acid (Enoxolone) is the major bioactive component of Glycyrrhizae Radix and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties.
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    Diammonium Glycyrrhizinate
    Diammonium Glycyrrhizin
    T052279165-06-3
    Diammonium Glycyrrhizinate (Glycyrrhizin) , an extensively used anti-inflammatory agent, is isolated from the licorice root. It is metabolized to glycyrrhetinic acid, which inhibits 11-β-hydroxysteroid dehydrogenase and other enzymes involved in the metabolism of corticosteroids. Therefore, glycyrrhizic acid, the main and sweet component of licorice, has been studied for its ability to cause hypermineralocorticoidism with potassium loss and sodium retention, edema, increased blood pressure, as well as inhibited the renin-angiotensin-aldosterone system.
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    Mycophenolic acid
    Mycophenolate, RS-61443
    T133524280-93-1
    Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.
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    3-Hydroxybenzaldehyde
    T4778100-83-4
    3-Hydroxybenzaldehyde is a compound useful in organic synthesis.
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    Mycophenolate Mofetil
    TM-MMF, RS 61443
    T6293128794-94-5
    Mycophenolate Mofetil (TM-MMF), an immunosuppressive agent, is the 2-morpholinoethyl ester of mycophenolic acid (MPA), and an inhibitor of inosine monophosphate dehydrogenase (IMPDH).
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    Isomalt
    Palatinitol, Palatinit
    T796464519-82-0
    Isomalt (Palatinitol) is a mixture of 1,6-mannitol glucopyranoside and 1,6-sorbitol glucopyranoside
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    Isovaleramide
    3-Methylbutanamide
    T0361541-46-8
    Isovaleramide (3-Methylbutanamide) is an anticonvulsant molecule isolated from Valeriana pavonii, which can inhibit the liver alcohol dehydrogenases.
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    Benzyl alcohol
    Benzoyl alcohol, Benzenemethanol, Phenylcarbinol, Phenylmethanol
    T0732100-51-6
    Benzyl alcohol (Benzenemethanol), a colorless liquid, is an aromatic alcohol with a mild pleasant aromatic odor.
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