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dehydrogenase

" in TargetMol Product Catalog
  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
18β-Glycyrrhetinic acid
Glycyrrhetin, Enoxolone
T0036471-53-4
18β-Glycyrrhetinic acid (Enoxolone) is the major bioactive component of Glycyrrhizae Radix and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties.
  • $29
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Mycophenolic acid
RS-61443, Mycophenolate
T133524280-93-1
Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.
  • $40
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3-Nitropropanoic acid
β-Nitropropionic acid, Bovinocidin, 3-NP acid, 3-NP
T3009504-88-1
3-Nitropropanoic acid (Bovinocidin) is an irreversible inhibitor of succinate dehydrogenase.
  • $31
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Sodium dichloroacetate
Sodium Dichloroacetate, Sodium dichloroacetate (DCA), Sodium bichloroacetic acid, DCA sodium salt
T36042156-56-1
Sodium dichloroacetate (BCA) , a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion channel axis, trigger apoptosis in cancer cells, and inhibit tumor growth.
  • $31
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Tenuifoliside B
T5702139726-36-6
Tenuifoliside B is a natural product from the roots of Polygala tenuifolia.And is a target lactate dehydrogenase inhibitor. Tenuifoliside B has cognitive improving and cerebral protective effects. it can inhibit potassium cyanide (KCN)-induced hypoxia and scopolamine-induced memory impairment in mice.
  • $72
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Sibiricose A5
T5S2195107912-97-0
Sibiricose A5 is a lactate dehydrogenase inhibitor, it displays antidepressant-like, and antioxidant actions. Sibiricose A5 can protect PC12 cells damage induced by P. tenuifolia.
  • $30
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TargetMol | Inhibitor Sale
Gossypol
Pogosin, NSC 56817, BL 193
T6518303-45-7
Gossypol (BL 193) Acetate is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes.
  • $33
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Dihydrouracil
5,6-Dihydrouracil
T4886504-07-4
5,6-Dihydrouracil (5,6-Dihydrouracil) is an intermediate breakdown product of uracil.
  • $29
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TargetMol | Inhibitor Sale
Glucose-6-phosphate dehydrogenase
G6PDH, G6PD
T738969001-40-5
Glucose-6-phosphate dehydrogenase is a rate-controlling enzyme of the pentose phosphate pathway (PPP) that catalyzes the oxidative dehydrogenation of glucose-6-phosphate to produce glucose-6-phosphate and NADPH.It is a sex-linked metabolic enzyme involved in the shunting of hexose monophosphate.
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Rotenone
Rotocide, Rotenon, Paraderil, Dactinol, Barbasco
T297083-79-4
Rotenone is a natural plant-derived insecticide that acts as an inhibitor of mitochondrial electron transport chain complex I. It promotes the generation of mitochondrial reactive oxygen species, induces apoptosis, and is commonly used to establish Parkinson's disease models.
  • $42
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Diammonium Glycyrrhizinate
Diammonium Glycyrrhizin
T052279165-06-3
Diammonium Glycyrrhizinate (Glycyrrhizin) , an extensively used anti-inflammatory agent, is isolated from the licorice root. It is metabolized to glycyrrhetinic acid, which inhibits 11-β-hydroxysteroid dehydrogenase and other enzymes involved in the metabolism of corticosteroids. Therefore, glycyrrhizic acid, the main and sweet component of licorice, has been studied for its ability to cause hypermineralocorticoidism with potassium loss and sodium retention, edema, increased blood pressure, as well as inhibited the renin-angiotensin-aldosterone system.
  • $43
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DL-Glyceric Acid
Glyceric Acid
T19289473-81-4
DL-Glyceric Acid is an endogenous metabolite that serves as a substrate for Pseudomonas aeruginosa's 3-hydroxyisobutyrate dehydrogenase (PA0743), catalyzing the reaction (Km = 19.8 mM).
  • $30
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Glycyrrhizic acid
Glycyrrhizin
T27411405-86-3
Glycyrrhizic acid (Glycyrrhizin), the active ingredient in licorice, is a triterpene saponins and an antagonist of HMGB1. Glycyrrhizic acid has the potential to be used in cancer, diabetes and other research.
  • $30
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Methylmalonic acid
NSC 25201, MMA, Methylpropanedioic acid, Methylmalonate, Isosuccinic acid
T4817516-05-2
Methylmalonic acid is an indicator of vitamin B-12 deficiency in cancer patients.Methylmalonic acid is a competitive succinate dehydrogenase inhibitor.
  • $33
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Mycophenolate Mofetil
TM-MMF, RS 61443
T6293128794-94-5
Mycophenolate Mofetil (TM-MMF), an immunosuppressive agent, is the 2-morpholinoethyl ester of mycophenolic acid (MPA), and an inhibitor of inosine monophosphate dehydrogenase (IMPDH).
  • $35
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Isomalt
Palatinitol, Palatinit
T796464519-82-0
Isomalt (Palatinitol) is a mixture of 1,6-mannitol glucopyranoside and 1,6-sorbitol glucopyranoside
  • $42
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2-Methylaminoethanol
N-Methylethanolamine
TN2779109-83-1
2-Methylaminoethanol inhibits High affinity choline transporter 1 and also inhibits Betaine aldehyde dehydrogenase in Escherichia coli.
  • $29
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Citric acid trilithium salt tetrahydrate
Trilithium citrate tetrahydrate, Lithium citrate tribasic tetrahydrate
T02566080-58-6
Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy of psychiatric disease. It has shown the effects of signaling pathways and metabolic in the brain based on the particular disease and clinical condition model. According to the reports, Citric acid trilithium salt tetrahydrate was used as a mood stabilizer when treating bipolar mood disorders (BD) and lower the risk of self-harm in BD patient. In addition,Citric acid trilithium salt tetrahydrate has been the choice drug in the therapy of acute manic episodes.Citric acid trilithium salt tetrahydrate also could dissolve uric acid crystals in urine achieved from patients with gout. Besides,Citric acid trilithium salt tetrahydrate have some dose-dependent side-effects. The the main side-effects of Lithium Citrate is the tendency to inhibit the prostatic acid phosphatase enzyme (PAP), which result in the accumulation of PAP.
  • $29
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D-Mannitol
Osmitrol, Mannitol, Mannite
T041469-65-8
D-Mannitol (Mannitol) is a diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. D-Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.
  • $46
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Benzyl alcohol
Phenylmethanol, Phenylcarbinol, Benzoyl alcohol, Benzenemethanol
T0732100-51-6
Benzyl alcohol (Benzenemethanol), a colorless liquid, is an aromatic alcohol with a mild pleasant aromatic odor.
  • $40
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Orotic acid
Vitamin B13, 6-Carboxyuracil
T074665-86-1
Orotic acid (Vitamin B13) is an intermediate product in pyrimidine metabolism.
  • $38
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Ethionamide
Ethinamide, Bayer 5312, 2-ethylthioisonicotinamide
T1165536-33-4
Ethionamide (2-ethylthioisonicotinamide) is a nicotinamide derivative, with antibacterial activity, used to treat tuberculosis. Although the exact mechanism of action of ethionamide is unknown, it may inhibit the synthesis of mycolic acid, a saturated fatty acid found in the bacterial cell wall, thereby inhibiting bacterial cell wall synthesis. This eventually leads to bacterial cell wall disruption and cell lysis. Ethionamide may be bacteriostatic or bactericidal in action, depending on the concentration of the drug at the site of infection and the susceptibility of the organism involved.
  • $31
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Daidzin
NPI-031D, Daidzoside, Daidzein 7-O-glucoside, Daidzein 7-glucoside
T2901552-66-9
Daidzin (Daidzoside) is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities.
  • $37
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4-Hydroxynonenal
4-HNE
T1014875899-68-2
4-Hydroxynonenal (4-HNE) (4-HNE) is an oxidative/nitrosative stress biomarker. It is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2).
  • $48
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