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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T38796L | MBP MAPK Substrate acetate | MBP MAPK Substrate acetate(138028-00-9 free base) | MAPK |
MBP MAPK Substrate acetate can be used as an exogenous substrate for MAPK. | |||
T36010 | P38 MAPK Inhibitor | p38 MAPK | |
p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase (IC50 = 35 nM). It inhibits senescence induced by the oncogene RAS. | |||
T12347 | P38-α MAPK-IN-1 | p38 MAPK , Autophagy | |
p38-α MAPK-IN-1 is a MAPK14 (p38-α) inhibitor(IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay). | |||
T63119 | NF-κB/MAPK-IN-1 | NF-κB , MAPK | |
NF-κB/MAPK-IN-1 is a potent dual inhibitor of the NF-κB and MAPK pathways with potential anti-inflammatory activity, inhibition of NO production, and inhibition of LPS-induced activation of iNOS, COX-2, ERΚ and P38. NF-κ... | |||
T35420 | (S)-p38 MAPK Inhibitor III | (S)-p38 MAPK Inhibitor III | |
(S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro). It is cell-permeable, potently blocking the release of TNF-α and IL-1β from human peripheral blood mononucle... | |||
T38796 | MBP MAPK Substrate | ||
MBP MAPK Substrate is used as an exogenous substrate for MAPK. | |||
T16424 | P38 MAPK-IN-1 | p38 MAPK | |
p38 MAPK-IN-1 displays sustained levels, low clearance, and good bioavailability. p38 MAPK-IN-1 is a novel effective and selective inhibitor of p38 MAPK (IC50: 68 nM). | |||
T11241 | P38 MAPK-IN-2 | Others | |
p38 MAPK-IN-2 is an inhibitor of p38 kinase. | |||
T36011 | P38 MAP Kinase Inhibitor IV | p38 MAPK Inhibitor IV | |
p38 MAPK inhibitor IV is an ATP-competitive inhibitor of p38 MAP kinases with IC50 values of 0.13, 0.55, 5.47, and 8.63 μM for p38α, p38β, p38x, and p38δ, respectively, in vitro.[1] It also inhibits LPS-induced TNF-α an... | |||
T70638 | P38-α MAPK-IN-5 | ||
P38-α MAPK-IN-5 is a potent inhibitor of p38α, demonstrating inhibitory concentrations (IC50) of 0.1 nM for p38α, 0.2 nM for p38β, 944 nM for p38γ, and 4100 nM for p38δ. It exhibits anti-inflammatory properties and holds... | |||
T60754 | MAPK-IN-1 | ||
MAPK-IN-1 (Compound 2) is an inhibitor of MAPK signaling pathway with anti-neuroinflammatory and neuroprotective activity that can be used for the research of Alzheimer's disease. MAPK-IN-1 inhibits AChE with an IC 50 of... | |||
T79572 | MAPK-IN-2 | EGFR | |
MAPK-IN-2 (compound 3h) is an efficacious MAPK inhibitor with antineoplastic properties that significantly hinders proliferation across various cancer cell lines. It demonstrates robust suppression of the MAPK pathway (E... | |||
T61803 | P38 MAPK-IN-3 | ||
p38 MAPK-IN-3 (Compound 2c) is a potent inhibitor of p38α MAPK, displaying antitumor properties by promoting apoptosis and increasing reactive oxygen species (ROS) production [1]. | |||
T61091 | P38-α MAPK-IN-4 | ||
p38-α MAPK-IN-4 (Compound 69) is a selective inhibitor of p38α MAPK, demonstrating potent inhibition with an IC50 of 1.5 μM. It effectively and swiftly mitigates the onset of mechanical allodynia (MA) in vivo [1]. | |||
T62359 | TLR4/NF-κB/MAPK-IN-1 | ||
TLR4/NF-κB/MAPK-IN-1 is a novel antineuroinflammatory agent that functions by inhibiting the TLR4/NF-κB/MAPK pathways. | |||
T78838 | Akt/NF-κB/MAPK-IN-1 | p38 MAPK | |
Akt/NF-κB/MAPK-IN-1 (compound 2m) serves as a potent, orally active inhibitor targeting NO with an IC50 of 7.70 μM and demonstrates low toxicity. This compound exerts anti-inflammatory effects by impeding the Akt/NF-κB a... | |||
TN1445 | Bisabolangelone | p38 MAPK , MAPK | |
Bisabolangelone has anti-tumor, anti-inflammatory, anti-microbial, and antioxidant activities, it inhibits dendritic cell functions by blocking MAPK and NF-κB signaling. | |||
T64587 | P44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695R | ||
p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695R is a useful organic compound for research related to life sciences and the catalog number is T64587. | |||
T9697 | ASK1-IN-1 | ASK | |
ASK1-IN-1 is an inhibitor of apoptosis signal-regulating kinase 1 which is a key mediator in the apoptotic and inflammatory cellular stress response with an IC50 of 21 nM in biochemica assays. | |||
T3400 | Bakuchiol | p38 MAPK , DNA/RNA Synthesis , Autophagy | |
Bakuchiol possesses anti-tumor,and anti-helmenthic properties. It has cytotoxic activity, mainly due to its DNA polymerase1 inhibiting activity. Bakuchiol has anti-bacterial activity against oral pathogens, has great pot... |