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Search Results for " mapk "

20

Compounds

Cat No. Product Name Synonyms Targets
T38796L MBP MAPK Substrate acetate MBP MAPK Substrate acetate(138028-00-9 free base) MAPK
MBP MAPK Substrate acetate can be used as an exogenous substrate for MAPK.
T36010 P38 MAPK Inhibitor p38 MAPK
p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase (IC50 = 35 nM). It inhibits senescence induced by the oncogene RAS.
T12347 P38-α MAPK-IN-1 p38 MAPK , Autophagy
p38-α MAPK-IN-1 is a MAPK14 (p38-α) inhibitor(IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay).
T63119 NF-κB/MAPK-IN-1 NF-κB , MAPK
NF-κB/MAPK-IN-1 is a potent dual inhibitor of the NF-κB and MAPK pathways with potential anti-inflammatory activity, inhibition of NO production, and inhibition of LPS-induced activation of iNOS, COX-2, ERΚ and P38. NF-κ...
T35420 (S)-p38 MAPK Inhibitor III (S)-p38 MAPK Inhibitor III
(S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro). It is cell-permeable, potently blocking the release of TNF-α and IL-1β from human peripheral blood mononucle...
T38796 MBP MAPK Substrate
MBP MAPK Substrate is used as an exogenous substrate for MAPK.
T11241 P38 MAPK-IN-2 Others
p38 MAPK-IN-2 is an inhibitor of p38 kinase.
T16424 P38 MAPK-IN-1 p38 MAPK
p38 MAPK-IN-1 displays sustained levels, low clearance, and good bioavailability. p38 MAPK-IN-1 is a novel effective and selective inhibitor of p38 MAPK (IC50: 68 nM).
T36011 P38 MAP Kinase Inhibitor IV p38 MAPK Inhibitor IV
p38 MAPK inhibitor IV is an ATP-competitive inhibitor of p38 MAP kinases with IC50 values of 0.13, 0.55, 5.47, and 8.63 μM for p38α, p38β, p38x, and p38δ, respectively, in vitro.[1] It also inhibits LPS-induced TNF-α an...
T70638 P38-α MAPK-IN-5
P38-α MAPK-IN-5 is a potent inhibitor of p38α, demonstrating inhibitory concentrations (IC50) of 0.1 nM for p38α, 0.2 nM for p38β, 944 nM for p38γ, and 4100 nM for p38δ. It exhibits anti-inflammatory properties and holds...
T60754 MAPK-IN-1
MAPK-IN-1 (Compound 2) is an inhibitor of MAPK signaling pathway with anti-neuroinflammatory and neuroprotective activity that can be used for the research of Alzheimer's disease. MAPK-IN-1 inhibits AChE with an IC 50 of...
T79572 MAPK-IN-2 EGFR
MAPK-IN-2 (compound 3h) is an efficacious MAPK inhibitor with antineoplastic properties that significantly hinders proliferation across various cancer cell lines. It demonstrates robust suppression of the MAPK pathway (E...
T61803 P38 MAPK-IN-3
p38 MAPK-IN-3 (Compound 2c) is a potent inhibitor of p38α MAPK, displaying antitumor properties by promoting apoptosis and increasing reactive oxygen species (ROS) production [1].
T61091 P38-α MAPK-IN-4
p38-α MAPK-IN-4 (Compound 69) is a selective inhibitor of p38α MAPK, demonstrating potent inhibition with an IC50 of 1.5 μM. It effectively and swiftly mitigates the onset of mechanical allodynia (MA) in vivo [1].
T78838 Akt/NF-κB/MAPK-IN-1 p38 MAPK
Akt/NF-κB/MAPK-IN-1 (compound 2m) serves as a potent, orally active inhibitor targeting NO with an IC50 of 7.70 μM and demonstrates low toxicity. This compound exerts anti-inflammatory effects by impeding the Akt/NF-κB a...
T62359 TLR4/NF-κB/MAPK-IN-1
TLR4/NF-κB/MAPK-IN-1 is a novel antineuroinflammatory agent that functions by inhibiting the TLR4/NF-κB/MAPK pathways.
TN1445 Bisabolangelone p38 MAPK , MAPK
Bisabolangelone has anti-tumor, anti-inflammatory, anti-microbial, and antioxidant activities, it inhibits dendritic cell functions by blocking MAPK and NF-κB signaling.
T9697 ASK1-IN-1 ASK
ASK1-IN-1 is an inhibitor of apoptosis signal-regulating kinase 1 which is a key mediator in the apoptotic and inflammatory cellular stress response with an IC50 of 21 nM in biochemica assays.
T64587 P44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695R
p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695R is a useful organic compound for research related to life sciences and the catalog number is T64587.
T3400 Bakuchiol p38 MAPK , DNA/RNA Synthesis , Autophagy
Bakuchiol possesses anti-tumor,and anti-helmenthic properties. It has cytotoxic activity, mainly due to its DNA polymerase1 inhibiting activity. Bakuchiol has anti-bacterial activity against oral pathogens, has great pot...
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