cd4

Anti-Mouse CD4 Antibody (2G5.D) is an anti-mouse CD4 antibody widely used in research and experiments in the field of life sciences.

CD4 (81-92) is a peptide that was previously found to inhibit gp120 binding, HIV-1 infectivity, and syncytium formation.

Cyclic-di-GMP disodium (5GP-5GP disodium) is a STING agonist and a second messenger in bacteria. It is involved in a variety of processes in prokaryotes, including biofilm formation, motility, and cell cycle progression. Cyclic-di-GMP disodium (5GP-5GP disodium) exhibits antiproliferative activity against cancer cells, inducing increased CD4 receptor expression and cell cycle arrest, and is a novel therapeutic agent that can be developed to prevent or treat cancer.

YYA-021 inhibits HIV entry, with high anti-HIV activity and low cytotoxicity.

NBD-556 is a small molecule mimetic of CD4. NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding.

FGF22-IN-1 is a potential CD4 N-terminal immunoglobulin variable region-like domain (CD4 D1) inhibitor.FGF22-IN-1 inhibits the interaction between CD4 and major histocompatibility complex (MHC) class II proteins and suppresses the immune response.

Ibalizumab(TMB-355) is a humanized IgG4 monoclonal antibody that acts as a CD4 receptor inhibitor, blocking the entry of HIV-1 into cells by binding to the CD4 receptor.Ibalizumab has anti-HIV-1 infectious activity and may be used to maintain normal immune function.

Ingenol mebutate (Ingenol 3-Angelate) is a potent activator of PKC subtypes including PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM. Ingenol mebutate exhibits antiinflammatory and antitumor activity.

(4S,5S)-(+)-Germacrone-4,5-epoxide inhibits certain subtypes of cytochrome P450 (CYP).

Moringin is an isothiocyanate obtained from myrosinase-mediated hydrolysis of the glucosinolate precursor glucoMoringin present in Moringa oleifera seeds. Moringin has anti-inflammatory and antioxidative properties.

Physalin H is an Hh signaling inhibitor blocks GLI1-DNA-complex formation, it also strong quinone reductase induction activity with IR (Induction ratio, QR induction activity) value of 3.74±0.02. Physalin H shows immunosuppressive effects on T cells both

Anti-Mouse CD4 Antibody (YTS 191) is a rat-derived IgG2b antibody that inhibits the mouse CD4 antigen.

Anti-CD4 Antibody (OKT-4) is a mouse IgG2b, κ chimeric antibody that targets human CD4. The recommended isotype control for Anti-CD4 Antibody (OKT-4) is Mouse IgG2b kappa, Isotype Control.

The Anti-Mouse CD4 Antibody (GK1.5) is a rat-derived IgG2b kappa isotype antibody targeting CD4 in mice. Its isotype control is designated as RatIgG2bkappa, Isotype Control.

Anti-human CD4 antibody isotype control subtype is Mouse IgG1, κ.

Anti-CD4 Antibody (Hu5A8) is a humanized IgG4 monoclonal antibody targeting CD4. Recommended isotype control: Human IgG4(S228P) kappa, Isotype Control.

[(Cys(Bzl)84, Glu(OBzl)85)]CD4 (81-92) is a selective HIV-1 inhibitor that blocks the interaction between HIV-1 and CD4 molecules, thereby inhibiting viral infection and cell fusion. At a concentration of 25 μM, it can completely prevent fusion formation [1].

PDCD4-IN-1, a PDCD4 inhibitor (Kd : 350 nM), promotes BDNF expression in hippocampal neuronal cells HT-22.

HA-CD44 interaction inhibitor 1 is an anti-tumor agent, which is a hyaluronic acid inhibitor targeting CD44. HA-CD44 interaction inhibitor 1 can inhibit MDA-MB-231 cells with an EC50 of 1.77 μM.

HA-CD44 interaction inhibitor 3 (compound 5d) is an inhibitor of the Hyaluronic acid (HA)-CD44 interaction. It has inhibitory effects on MDA-MB-231 (CD44++) cells and MCF-7 (CD44--) cells with EC50 values of 4.24 μM and 14.74 μM, respectively. HA-CD44 interaction inhibitor 3 is applicable to cancer research.

CD437 (AHPN) is a specifc Retinoic Acid Receptor γ (RARγ) agonist.

Anti-Mouse CD44 Antibody (IM7) is a monoclonal antibody targeting CD44 in mice.

Antitumor Agent-108 (Compound 5), an inhibitor of the Hyaluronic Acid (HA)-CD44 interaction, effectively disrupts cancer spheroid integrity and exhibits antiproliferative activity against cancer cells [1].

Anti-CD40 Antibody (G28.5) is a chimeric mouse IgG1, κ antibody that specifically targets human CD40. The recommended isotype control for Anti-CD40 Antibody (G28.5) is Mouse IgG1 kappa, Isotype Control.