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Iscalimab
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Catalog No. T77043Cas No. 2031153-61-2
Alias OM11-62MF, OM1162MF, CFZ-533, CFZ533
Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren's syndrome.
Iscalimab
Iscalimab
😃Good
Catalog No. T77043Alias OM11-62MF, OM1162MF, CFZ-533, CFZ533Cas No. 2031153-61-2
Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren's syndrome.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $297 | In Stock | In Stock | |
| 5 mg | $993 | In Stock | In Stock | |
| 10 mg | $1,690 | - | In Stock | |
| 25 mg | $2,490 | - | In Stock | |
| 50 mg | $3,380 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:100% (SEC-HPLC)
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| Description | Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren's syndrome. |
| Targets&IC50 | CD40:0.3 nM |
| In vivo | Iscalimab can prolong the rejection free survival of kidney allografts in cynomophagous monkeys. [1] In a preclinical porcine to rhesus monkey kidney xenotransplantation model, Iscalimab was administered at a load dose of 30 mg/kg on day 0, followed by weekly subcutaneous injections of 10 mg/kg for 10 weeks, then reduced to 10 mg/kg every 2 weeks, and clinically significant rejection was found. [2] |
| Synonyms | OM11-62MF, OM1162MF, CFZ-533, CFZ533 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | TNFRSF5/CD40 |
| Molecular Weight | 146.08 kDa |
| Cas No. | 2031153-61-2 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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