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Iscalimab (Synonyms: OM11-62MF, OM1162MF, CFZ-533, CFZ533)
Catalog No. T77043 Copy Product Info
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Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren's syndrome.
Iscalimab
Copy Product Info🥰Excellent
Catalog No. T77043
Synonyms OM11-62MF, OM1162MF, CFZ-533, CFZ533
Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren's syndrome.
Iscalimab
Cas No. 2031153-61-2
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $297 | In Stock | In Stock | |
| 5 mg | $993 | In Stock | In Stock | |
| 10 mg | $1,690 | - | In Stock | |
| 25 mg | $2,490 | - | In Stock | |
| 50 mg | $3,380 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:100% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren's syndrome. |
| Targets&IC50 | CD40:0.3 nM |
| In vivo | Iscalimab can prolong the rejection free survival of kidney allografts in cynomophagous monkeys. [1] In a preclinical porcine to rhesus monkey kidney xenotransplantation model, Iscalimab was administered at a load dose of 30 mg/kg on day 0, followed by weekly subcutaneous injections of 10 mg/kg for 10 weeks, then reduced to 10 mg/kg every 2 weeks, and clinically significant rejection was found. [2] |
| Synonyms | OM11-62MF, OM1162MF, CFZ-533, CFZ533 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | TNFRSF5/CD40 |
| Molecular Weight | 146.08 kDa |
| Cas No. | 2031153-61-2 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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