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Iscalimab (Synonyms: OM11-62MF, OM1162MF, CFZ-533, CFZ533)
Catalog No. T77043 Copy Product Info
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Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren's syndrome.
Iscalimab
Copy Product Info🥰Excellent
Catalog No. T77043
Synonyms OM11-62MF, OM1162MF, CFZ-533, CFZ533
Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren's syndrome.
Iscalimab
Cas No. 2031153-61-2
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $297 | In Stock | In Stock | |
| 5 mg | $993 | In Stock | In Stock | |
| 10 mg | $1,690 | - | In Stock | |
| 25 mg | $2,490 | - | In Stock | |
| 50 mg | $3,380 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:100% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren's syndrome. |
| Targets&IC50 | CD40:0.3 nM |
| In vivo | Iscalimab can prolong the rejection free survival of kidney allografts in cynomophagous monkeys. [1] In a preclinical porcine to rhesus monkey kidney xenotransplantation model, Iscalimab was administered at a load dose of 30 mg/kg on day 0, followed by weekly subcutaneous injections of 10 mg/kg for 10 weeks, then reduced to 10 mg/kg every 2 weeks, and clinically significant rejection was found. [2] |
| Synonyms | OM11-62MF, OM1162MF, CFZ-533, CFZ533 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | TNFRSF5/CD40 |
| Molecular Weight | 146.08 kDa |
| Cas No. | 2031153-61-2 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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