Shopping Cart
Remove All
Your shopping cart is currently empty
Iscalimab
(Synonyms: OM11-62MF, OM1162MF, CFZ-533, CFZ533) Copy Product Info
🥰Excellent
Synonyms: OM11-62MF, OM1162MF, CFZ-533, CFZ533
Catalog No. T77043 Copy Product Info
🥰Excellent
Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren's syndrome.
Cas No. 2031153-61-2
Customer service consultation
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $297 | In Stock | In Stock | |
| 5 mg | $993 | In Stock | In Stock | |
| 10 mg | $1,690 | - | In Stock | |
| 25 mg | $2,490 | - | In Stock | |
| 50 mg | $3,380 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
Batch Information
Select Batch
Purity:100% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren's syndrome. |
| Targets & IC50 | CD40:0.3 nM |
| In vivo | Iscalimab can prolong the rejection free survival of kidney allografts in cynomophagous monkeys. [1] In a preclinical porcine to rhesus monkey kidney xenotransplantation model, Iscalimab was administered at a load dose of 30 mg/kg on day 0, followed by weekly subcutaneous injections of 10 mg/kg for 10 weeks, then reduced to 10 mg/kg every 2 weeks, and clinically significant rejection was found. [2] |
| Synonyms | OM11-62MF, OM1162MF, CFZ-533, CFZ533 |
| Reactivity | Human |
| Verified Activity | Immobilized Human CD40 Protein (His) (TMPY-01181) at 1 μg/mL (100 μL/well) can bind Iscalimab. The EC50 is 2.16 ng/mL. |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | TNFRSF5/CD40 |
| Molecular Weight | 146.08 kDa |
| Cas No. | 2031153-61-2 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Calculator
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Preview
Related Tags: Iscalimab chemical structure | Iscalimab in vivo | Iscalimab molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.