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HX009 is a bispecific antibody targeting PD-1 and CD47 (EC50=0.05 nM/0.24 nM). It binds and blocks PD-1 and CD47, selectively localizes to the tumor microenvironment, and reduces hematotoxicity. It can be used to study non-Hodgkin lymphoma (NHL).

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $372 | - | In Stock | |
| 5 mg | $1,090 | - | In Stock | |
| 10 mg | $1,780 | - | In Stock | |
| 25 mg | $3,290 | - | In Stock |
| Description | HX009 is a bispecific antibody targeting PD-1 and CD47 (EC50=0.05 nM/0.24 nM). It binds and blocks PD-1 and CD47, selectively localizes to the tumor microenvironment, and reduces hematotoxicity. It can be used to study non-Hodgkin lymphoma (NHL). |
| Targets&IC50 | PD-1:0.05 nM (EC50), CD47:2.6 nM (EC50) |
| In vivo | In a subcutaneous Raji xenograft lymphoma model in immunodeficient NOD/SCID mice, HX009 (10 mg/kg) induced significant growth delay (approximately 54% TGI) [1]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1 EU/mg |
| Conjucates | Unconjugated |
| Molecular Weight | 173.16 kDa |
| Isotype | Human IgG4SP kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature | Store at -80°C | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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