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HX009
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Catalog No. T9901A-797 Copy Product Info
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HX009 is a bispecific antibody targeting PD-1 and CD47 (EC50=0.05 nM/0.24 nM). It binds and blocks PD-1 and CD47, selectively localizes to the tumor microenvironment, and reduces hematotoxicity. It can be used to study non-Hodgkin lymphoma (NHL).
HX009
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $372 | - | In Stock | |
| 5 mg | $1,090 | - | In Stock | |
| 10 mg | $1,780 | - | In Stock | |
| 25 mg | $3,290 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:>95% (SDS-PAGE); 99.56% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | HX009 is a bispecific antibody targeting PD-1 and CD47 (EC50=0.05 nM/0.24 nM). It binds and blocks PD-1 and CD47, selectively localizes to the tumor microenvironment, and reduces hematotoxicity. It can be used to study non-Hodgkin lymphoma (NHL). |
| Targets & IC50 | PD-1:0.05 nM (EC50), CD47:2.6 nM (EC50) |
| In vivo | In a subcutaneous Raji xenograft lymphoma model in immunodeficient NOD/SCID mice, HX009 (10 mg/kg) induced significant growth delay (approximately 54% TGI) [1]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1 EU/mg |
| Conjucates | Unconjugated |
| Molecular Weight | 173.16 kDa |
| Isotype | Human IgG4SP kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature Store at -80°C Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: HX009 in vivo | HX009 molecular weight
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