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HX009

Catalog No. T9901A-797 Copy Product Info
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HX009 is a bispecific antibody targeting PD-1 and CD47 (EC50=0.05 nM/0.24 nM). It binds and blocks PD-1 and CD47, selectively localizes to the tumor microenvironment, and reduces hematotoxicity. It can be used to study non-Hodgkin lymphoma (NHL).

HX009

Copy Product Info
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Catalog No. T9901A-797

HX009 is a bispecific antibody targeting PD-1 and CD47 (EC50=0.05 nM/0.24 nM). It binds and blocks PD-1 and CD47, selectively localizes to the tumor microenvironment, and reduces hematotoxicity. It can be used to study non-Hodgkin lymphoma (NHL).

HX009
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$372-In Stock
5 mg$1,090-In Stock
10 mg$1,780-In Stock
25 mg$3,290-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:>95% (SDS-PAGE); 99.56% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
HX009 is a bispecific antibody targeting PD-1 and CD47 (EC50=0.05 nM/0.24 nM). It binds and blocks PD-1 and CD47, selectively localizes to the tumor microenvironment, and reduces hematotoxicity. It can be used to study non-Hodgkin lymphoma (NHL).
Targets&IC50
PD-1:0.05 nM (EC50), CD47:2.6 nM (EC50)
In vivo
In a subcutaneous Raji xenograft lymphoma model in immunodeficient NOD/SCID mice, HX009 (10 mg/kg) induced significant growth delay (approximately 54% TGI) [1].
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Chemical Properties
Molecular Weight173.16 kDa
Antibody Information
IsotypeHuman IgG4SP kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at low temperature | Store at -80°C | Shipping with blue ice.

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