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Anti-human CD45RO Antibody (5F958)

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Catalog No. TMAB-07411

Anti-human CD45RO Antibody (5F958) is a Mouse antibody targeting human CD45RO. Anti-human CD45RO Antibody (5F958) can be used in FCM.

Anti-human CD45RO Antibody (5F958)

Anti-human CD45RO Antibody (5F958)

😃Good
Catalog No. TMAB-07411
Anti-human CD45RO Antibody (5F958) is a Mouse antibody targeting human CD45RO. Anti-human CD45RO Antibody (5F958) can be used in FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 μg$3557-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-human CD45RO Antibody (5F958) is a Mouse antibody targeting human CD45RO. Anti-human CD45RO Antibody (5F958) can be used in FCM.
Ig Type
Mouse IgG2a, k
Clone
5F958
Reactivity
Human
Application
FCM
Recommended Dose
FCM: 1μg/Test
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationMembrane; Single-pass type I membrane protein. Membrane raft. Note=Colocalized with DPP4 in membrane rafts.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M PBS (pH7.4).
Research BackgroundThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling
Antigen Details
Gene Name
PTPRC
Gene ID
5788
Protein Name
Receptor-type tyrosine-protein phosphatase C
Function
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.
Chemical Properties
Molecular WeightActual: 220 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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