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Anti-CD40 Monoclonal Antibody (5E622)
(Synonyms: TNFRSF5, p50, CDW40, Bp50) Copy Product Info
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Synonyms: TNFRSF5, p50, CDW40, Bp50
Catalog No. TMAT-0413 Copy Product Info
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Anti-CD40 Monoclonal Antibody (5E622) is a Mouse antibody targeting CD40. Anti-CD40 Monoclonal Antibody (5E622) can be used in IF.
Anti-CD40 Monoclonal Antibody
(5E622)
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Product Introduction
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| Description | Anti-CD40 Monoclonal Antibody (5E622) is a Mouse antibody targeting CD40. Anti-CD40 Monoclonal Antibody (5E622) can be used in IF. |
| Synonyms | TNFRSF5, p50, CDW40, Bp50 |
| Ig Type | IgG1 |
| Clone | 5E622 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IF: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | CD40 molecule, TNF receptor superfamily member 5. It is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of CD40 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CD40 |
| Gene ID | |
| Protein Name | Tumor necrosis factor receptor superfamily member 5 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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