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Synonyms: ITGA4, IA4
Anti-CD49D Monoclonal Antibody
(3H890)

| Description | Anti-CD49D Monoclonal Antibody (3H890) is a Mouse antibody targeting CD49D. Anti-CD49D Monoclonal Antibody (3H890) can be used in WB,FCM. |
| Synonyms | ITGA4, IA4 |
| Ig Type | IgG2a |
| Clone | 3H890 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD49D (AA: extra 833-977) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | ITGA4 |
| Gene ID | |
| Protein Name | Integrin alpha-4 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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