CD4

Anti-Mouse CD4 Antibody (2G5.D) is an anti-mouse CD4 antibody widely used in research and experiments in the field of life sciences.

CD4 (81-92) is a peptide that was previously found to inhibit gp120 binding, HIV-1 infectivity, and syncytium formation.

Cyclic-di-GMP disodium (5GP-5GP disodium) is a STING agonist and a second messenger in bacteria. It is involved in a variety of processes in prokaryotes, including biofilm formation, motility, and cell cycle progression. Cyclic-di-GMP disodium (5GP-5GP disodium) exhibits antiproliferative activity against cancer cells, inducing increased CD4 receptor expression and cell cycle arrest, and is a novel therapeutic agent that can be developed to prevent or treat cancer.

Ibalizumab(TMB-355) is a humanized IgG4 monoclonal antibody that acts as a CD4 receptor inhibitor, blocking the entry of HIV-1 into cells by binding to the CD4 receptor.Ibalizumab has anti-HIV-1 infectious activity and may be used to maintain normal immune function.

Ingenol mebutate (Ingenol 3-Angelate) is a potent activator of PKC subtypes including PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM. Ingenol mebutate exhibits antiinflammatory and antitumor activity.

Anti-Mouse CD4 Antibody (YTS 191) is a rat-derived IgG2b antibody that inhibits the mouse CD4 antigen.

Anti-CD4 Antibody (OKT-4) is a mouse IgG2b, κ chimeric antibody that targets human CD4. The recommended isotype control for Anti-CD4 Antibody (OKT-4) is Mouse IgG2b kappa, Isotype Control.

The Anti-Mouse CD4 Antibody (GK1.5) is a rat-derived IgG2b kappa isotype antibody targeting CD4 in mice. Its isotype control is designated as RatIgG2bkappa, Isotype Control.

Anti-human CD4 antibody isotype control subtype is Mouse IgG1, κ.

Anti-CD4 Antibody (Hu5A8) is a humanized IgG4 monoclonal antibody targeting CD4. Recommended isotype control: Human IgG4(S228P) kappa, Isotype Control.

[(Cys(Bzl)84, Glu(OBzl)85)]CD4 (81-92) is a selective HIV-1 inhibitor that blocks the interaction between HIV-1 and CD4 molecules, thereby inhibiting viral infection and cell fusion. At a concentration of 25 μM, it can completely prevent fusion formation [1].

PDCD4-IN-1, a PDCD4 inhibitor (Kd : 350 nM), promotes BDNF expression in hippocampal neuronal cells HT-22.

HA-CD44 interaction inhibitor 1 is an anti-tumor agent, which is a hyaluronic acid inhibitor targeting CD44. HA-CD44 interaction inhibitor 1 can inhibit MDA-MB-231 cells with an EC50 of 1.77 μM.

HA-CD44 interaction inhibitor 3 (compound 5d) is an inhibitor of the Hyaluronic acid (HA)-CD44 interaction. It has inhibitory effects on MDA-MB-231 (CD44++) cells and MCF-7 (CD44--) cells with EC50 values of 4.24 μM and 14.74 μM, respectively. HA-CD44 interaction inhibitor 3 is applicable to cancer research.

CD437 (AHPN) is a specifc Retinoic Acid Receptor γ (RARγ) agonist.

Anti-Mouse CD44 Antibody (IM7) is a monoclonal antibody targeting CD44 in mice.

Antitumor Agent-108 (Compound 5), an inhibitor of the Hyaluronic Acid (HA)-CD44 interaction, effectively disrupts cancer spheroid integrity and exhibits antiproliferative activity against cancer cells [1].

Anti-CD40 Antibody (G28.5) is a chimeric mouse IgG1, κ antibody that specifically targets human CD40. The recommended isotype control for Anti-CD40 Antibody (G28.5) is Mouse IgG1 kappa, Isotype Control.

Anti-CD47 Antibody (B6.H12) is a chimeric mouse IgG1 κ antibody that specifically targets human CD47. The recommended isotype control for Anti-CD47 Antibody (B6.H12) is Mouse IgG1 kappa, Isotype Control.

The Anti-CD44 Antibody (Hermes-1) is a chimeric rat-derived IgG2a, κ antibody targeting human CD44. The isotype control for the Anti-CD44 Antibody (Hermes-1) is RatIgG2akappa, Isotype Control.

Anti-Monkey/Human CD40L/CD154 Antibody (5C8) is an IgG2a inhibitor derived from mice that targets CD40L/CD154 in monkeys and humans.

Anti-Mouse CD47/IAP Antibody (MIAP301) is an IgG2a, κ antibody inhibitor derived from rats that targets mouse CD47/IAP.

Anti-Mouse CD40L/CD154 Antibody (MR-1) is an IgG antibody inhibitor derived from an American hamster, specifically targeting mouse CD40L/CD154.

Anti-Mouse CD40 Antibody (FGK4.5/FGK45) is a rat-derived IgG2a monoclonal antibody targeting mouse CD40, a type I transmembrane glycoprotein within the tumor necrosis factor receptor (TNFR) superfamily. CD40 functions as a costimulatory molecule, activating B cells, dendritic cells, monocytes, and other antigen-presenting cells (APC), thereby enhancing antitumor T cell responses.