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Results for "

alzheimer's

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    847
    TargetMol | Inhibitors_Agonists
  • Compound Libraries
    10
    TargetMol | Compound_Libraries
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    82
    TargetMol | Peptide_Products
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    26
    TargetMol | Inhibitory_Antibodies
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    TargetMol | Dye_Reagents
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    113
    TargetMol | Natural_Products
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    35
    TargetMol | Recombinant_Protein
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    10
    TargetMol | Disease_Modeling_Products
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    9
    TargetMol | Inhibitors_Agonists
GSK1940029
SCD inhibitor 1
T54271150701-66-8In house
GSK1940029 (SCD inhibitor 1) is an inhibitor of stearoyl-CoA desaturase (SCD).
  • $30 TargetMol
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Galanthamine hydrobromide
Galanthamine HBr, Galantamine hydrobromide
T00861953-04-4
Galanthamine hydrobromide (Galantamine hydrobromide), a long-acting and centrally active AChE inhibitor (IC50:410 nM), is an allosteric potentiator at neuronal nicotinic ACh receptors.
  • $36
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TargetMol | Citations Cited
Idebenone
CV-2619
T041258186-27-9
Idebenone (CV-2619) is a synthetic analogue of ubiquinone (Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC).
  • $40
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Nicergoline
Nimergoline, Nicergolinum
T113227848-84-6
Nicergoline (Nicergolinum) is an ergot derivative used to treat senile dementia and other disorders with vascular origins.
  • $30
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Nicotinamide riboside
T137951341-23-7
Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.
  • $50
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Nootkatone
T3S01954674-50-4
1. Nootkatone can provide effective tick control. 2. (+)-Nootkatone has antiallergic, anti-inflammatory, and antiplatelet activities. 3. Nootkatone can prevent obesity and improve physical performance through AMPK activation in skeletal muscle and liver.
  • $40
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β-Nicotinamide mononucleotide
β-NM, NMN
T47211094-61-7
β-nicotinamide mononucleotide (NMN) is a natural nucleotide and a key intermediate in the synthesis of coenzyme I (NAD+). β-nicotinamide mononucleotide is involved in a number of biochemical reactions in the human body, which are related to immunity and metabolism.
  • $30
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Nicotinamide riboside chloride
T622023111-00-4
Nicotinamide riboside chloride, also known as NR and SRT647, is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+.
  • $31
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Methyl tridecanoate
TN69191731-88-0
Methyl tridecanoate is a natural product.
  • $29
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Physostigmine Salicylate
T013057-64-7
Physostigmine, a parasympathomimetic alkaloid, is a reversible cholinesterase inhibitor. It extracts from the Calabar bean.
  • $50
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(-)-Huperzine A
Huperzine A, HupA
T3026102518-79-6
(-)-Huperzine A (HupA) , an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD).
  • $43
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Talatisamine
T3S187320501-56-8
1. Talatisamine (12 μM) and TEA (5mM) inhibits the enhanced I(K) caused by Aβ4 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+) loss related apoptotic response. 2. Talatisamine can therefore be considered
  • $33
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Verubecestat
MK-8931
T70111286770-55-5
Verubecestat (MK-8931) (MK-8931) is an effective and specific β-secretase inhibitor and β-site APP-cleaving enzyme 1 inhibitor or BACE1 protein inhibitor.
  • $34
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Blarcamesine
AVex-73, AE-37
T7780195615-83-9
Blarcamesine (AVex-73) is a muscarinic M1 agonist potentially for the treatment of Alzheimer's disease.
  • $40
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RSVA405
RSVA 405
T8476140405-36-3
RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitor
  • $44
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Isoastilbin
TN177254081-48-0
Isoastilbin is a dihydroflavonol glycoside compound found in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg/mL and possesses anti-acne and tyrosinase inhibition properties. Additionally, isoastilbin demonstrates neuroprotective, antioxidation, antimicrobial, and anti-apoptotic properties, indicating potential for Alzheimer's disease research.
  • $118
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Selegiline hydrochloride
R(-)-Deprenyl hydrochloride
T505014611-52-0
Selegiline hydrochloride is a selective, reversible inhibitor of MAO-B (Ki = 0.091 μM) over MAO-A (Ki = 9.06 μM). Monoamine oxidase (MAO) inhibitors have utility in ameliorating a variety of neurological conditions, including depression.
    Inquiry
    Protriptyline hydrochloride
    Protriptyline HCl
    T02041225-55-4
    Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline, a tricyclic secondary amine with an antidepressant property. Protriptyline hydrochloride (Protriptyline HCl) blocks the re-uptake of norepinephrine and serotonin by nerve terminals, thereby increasing available norepinephrine and serotonin. In addition, this agent exhibits anticholinergic activity.
    • $29
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    Deferoxamine Mesylate
    DFOM, Desferrioxamine B mesylate
    T1637138-14-7
    Deferoxamine Mesylate (DFOM) is an iron chelator and ferroptosis inhibitor. Deferoxamine Mesylate binds free iron into a stable complex and reduces iron accumulation. Deferoxamine Mesylate up-regulates HIF-1α levels and induces apoptosis.
    • $31
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    TargetMol | Citations Cited
    SEW​2871
    SEW2871
    T2171256414-75-2
    SEW 2871 is an orally available, highly selective S1P1 agonist with an EC50 of 13.8 nM.It reduces the number of lymphocytes in the blood and is used in studies related to diabetes, Alzheimer's disease, liver fibrosis, and inflammation. It activates ERK, Akt and Rac signaling pathways and induces S1P1 internalization and recycling.
    • $48
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    Xanomeline tartrate
    LY-246708 tartrate, LY246708 tartrate, LY 246708 tartrate
    T39010152854-19-8
    Xanomeline tartrate (LY 246708 tartrate) is an M1 and M4 mAChR agonist with antipsychotic-like activity that improves cognition and can be used in studies of schizophrenia and Alzheimer's disease.
    • $30
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    SRI-011381 hydrochloride
    SRI-011381 hydrochloride [1629138-41-5(free base)]
    T51292070014-88-7
    SRI-011381 hydrochloride, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
    • $39
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    TargetMol | Citations Cited
    PLX5622
    PLX-5622
    T71001303420-67-8
    PLX5622 is an orally active small-molecule CSF1R inhibitor that selectively depletes microglia in the brains of mice and rats. It is commonly used to establish models related to microglia-associated neuroinflammation, neurodegenerative diseases (such as Alzheimer's disease and Parkinson's disease), brain injury, and neuroimmune regulation.
    • $38
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    Aducanumab
    BIIB037
    T770421384260-65-4
    Aducanumab (BIIB037), A selective human immunoglobulin gamma-1 (IgG1) monoclonal antibody, targets the clustered form of amyloid beta (Aβ). Aducanumab shows brain permeability and may be used to treat Alzheimer's disease (AD).
    • $189
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    TargetMol | Inhibitor Hot