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Search Results for " caspase "

20

Compounds

Cat No. Product Name Synonyms Targets
T6005 Z-DEVD-FMK Caspase-3 Inhibitor Caspase
Z-DEVD-FMK (Caspase-3 Inhibitor) is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7, caspase-8, and caspase-10.
T11696 Ivachtin Caspase-3 Inhibitor VII Caspase
Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remaining caspases.
T21871 MMPSI Caspase-3/7 Inhibitor I Apoptosis , Caspase
MMPSI (Caspase-3/7 Inhibitor I) is a novel, non-peptide small molecule caspase 3 and caspase 7 inhibitor that reduces ischemic injury in isolated rabbit heart or cardiomyocytes and inhibits apoptosis of H16c2 cells in a ...
T70650 Caspase-6-IN-1 Others
Caspase-6-IN-1 is a novel Allosteric Inhibitor of Caspase-6 Activation, blocking the interaction between C6 and mHTT1-586.
T7019 Z-IETD-FMK Z-IE(OMe)TD(OMe)-FMK,Caspase-8 Inhibitor Caspase
Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective caspase 8 inhibitor, which has cell permeable.
T7020 Z-VAD-FMK Z-VAD(OH)-FMK,Caspase Inhibitor VI,Z-VAD Caspase
Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does not inhibit UCHL1 activity, even at concentrations up to 440 μM.
T72281 Caspase-9 Inhibitor III Ac-LEHD-cmk Others
Caspase-9 Inhibitor III (Ac-LEHD-cmk), a caspase-9 inhibitor, exhibits protective effects against ischemia-reperfusion-induced myocardial injury.
T36347 Ac-YVAD-CMK Caspase-1 Inhibitor II,Ac-Tyr-Val-Ala-Asp-chloromethylketone,Ac-Tyr-Val-Ala-Asp-CMK IL Receptor , Caspase , Immunology/Inflammation related , Pyroptosis
Ac-YVAD-CMK (Ac-Tyr-Val-Ala-Asp-CMK) is a selective and irreversible inhibitor of Caspase-1 and inhibits pyroptosis, IL-1β and IL-18. Ac-YVAD-CMK shows neuroprotective and anti-inflammatory capacity.
T76571 Caspase-8-IN-1
Caspase-8-IN-1 is a potent caspase-8 inhibitor [1] .
T82775 Caspase-3 activator 2 Caspase
Caspase-3 Activator 2 (Compound 2f) is a caspase 3 activator with cytotoxic effects on HL-60 and K562 cells, exhibiting IC 50 values of 33.52 μM and 76.90 μM, respectively [1]. It facilitates apoptosis, rendering it usef...
T79743 Caspase-3 activator 1 Pyroptosis
Caspase-3 activator 1 (compound 4b), a Ru(III) metal complex, effectively inhibits gastric tumor growth and metastasis by mediating caspase-3 cleavage. This cleavage enables Caspase-3 to process gasdermin E (GSDME), whic...
T63479 Caspase-3-IN-1 Others
Caspase-3-IN-1 is a potent inhibitor of Caspase-3 (IC50: 14.5 nM).
T82774 Caspase-3 activator 3 Caspase
Caspase-3 activator 3 (compound 2h) effectively induces apoptosis in HL-60 and K562 cells by substantially activating caspase-3, demonstrating antileukemic activity with IC50 values of 42.89 μM and 33.61 μM, respectively...
T72316 Caspase-3/7 activator 3 Others
Caspase-3/7 Activator 3 is a potent and tumor-selective compound that effectively activates Caspase-3/7, demonstrating significant anti-proliferative activity and a high capacity to induce apoptosis.
T72315 Caspase-3/7 activator 2 Others
Caspase-3/7 Activator 2 is a potent compound that selectively activates Caspase-3/7, demonstrating tumor specificity, anti-proliferative properties, and a high capacity for inducing apoptosis.
TP1466 Z-YVAD-FMK Caspase
AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.
T83963 Z-DEVD-FMK Caspase-3 Inhibitor Others
Z-DEVD-FMK, a Caspase-3 Inhibitor, is an irreversible, cell-permeable inhibitor of caspase-3/CPP32 that impedes tumor cell apoptosis. In vivo studies show it offers neuroprotection in rat hippocampi post-seizures and con...
T5S2076 Senkyunolide I Others , Caspase
1. Senkyunolide I has neuroprotective effect, associated with its anti-oxidation and anti-apoptosis properties.
TQ0146L Ac-DEVD-CHO acetate Caspase-3 Inhibitor I,N-acetyl-asp-glu-val-asp-al,Ac-DEVD-CHO acetate (169332-60-9 free base) Caspase
Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3.
T5S2283 Sesamolin p38 MAPK , Caspase , JNK
1. Sesamolin and Sesamin has neuroprotective effect. 2. Sesamolin protects microglia against H2O2-induced cell injury, by inhibiting of p38 MAPK and caspase-3 activation and ROS production. 3. Sesamolin and Sesamin can s...
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