T30531 |
BMS-561392
|
611227-74-8
|
98%
|
|
BMS-561392 is a tumor necrosis factor-α ( TNF-α) Invertase inhibitor.
|
TN1996 |
Nothofagin
|
11023-94-2
|
98%
|
|
Nothofagin has antioxidant, and antithrombotic activities, it possesses anti-inflammatory activity by inhibiting hyperpermeability, expression of CAMs, and adhes...
|
T10865 |
Cot inhibitor-1
|
915365-57-0
|
98%
|
|
Cot inhibitor-1 is a selective inhibitor of Cot protein kinase (also known as Tpl2 or MAP3K8) (IC50 at 28 nM). Cot inhibitor-1 inhibited TNF-alpha production in ...
|
T10866 |
Cot inhibitor-2
|
915363-56-3
|
98%
|
|
Cot inhibitor-2 is a cot (Tpl2/MAP3K8) inhibitor (IC50: 1.6 nM) with potency, selectivity and oral activity. cot inhibitor-2 inhibits LPS-stimulated TNF-α produc...
|
T29857 |
Alethine
|
646-08-2
|
98%
|
|
Alethine is a small molecule compound with antitumour activity and is used to treat tumours and infections. The alethine-induced up-regulation of TNFα increases ...
|
T10865L |
Cot inhibitor-1 hydrochloride
|
T10865L
|
98%
|
|
Cot inhibitor-1 hydrochloride is an inhibitor of tumor progression loci-2 kinase (IC50 = 28 nM) and inhibits the production of TNF-α in human whole blood (IC50 =...
|
T11484 |
GSK2593074A
|
1337531-06-2
|
98%
|
|
GSK2593074A is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.
|
T2434 |
LY 303511
|
154447-38-8
|
98%
|
|
LY303511, an inactive analogue of LY294002, is a mTOR inhibitor and no inhibition for PI3-K.
|
TN2180 |
Sappanchalcone
|
94344-54-4
|
98%
|
|
Sappanchalcone shows xanthine oxidase inhibitory activity, is a xanthine oxidase inhibitor.
|
T3426 |
Bacoside A
|
11028-00-5
|
98%
|
|
Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro. It exerts cytoprotect...
|
TN4592 |
Murrangatin
|
37126-91-3
|
98%
|
|
Murrangatin may be a valuable anti-tumor-promoting agent, it can significantly inhibit Epstein-Barr virus early antigen (EBV-EA) activation, and preserve the hig...
|
TN3635 |
Chlojaponilactone B
|
1449382-91-5
|
98%
|
|
Chlojaponilactone B has anti-inflammatory activity, it exhibits pronounced inhibition of nitric oxide (NO) production in lipopolysaccharide (LPS)-induced RAW 264...
|
TN4938 |
Samidin
|
477-33-8
|
98%
|
|
Samidin has anti-inflammatory properties through suppression of NF-κB and AP-1-mediated-genes in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells.
|
T5S0313 |
Liguiritigenin-7-O-D-apiosyl-4'-O-D-glucoside
|
199796-12-8
|
98%
|
|
Liquiritin apioside has antioxidant property by inducing glutathione (GSH) biosynthesis via the inhibition of cytokines and protected lung epithelial cells again...
|
TN5164 |
Trans-Hinokiresinol
|
17676-24-3
|
98%
|
|
Hinokiresinol is a novel inhibitor of LTB4 binding to the human neutrophils, it has antiallergic effect, it inhibits IgE-induced mouse passive cutaneous anaphyla...
|
TN1681 |
Gentianine
|
439-89-4
|
98%
|
|
Gentianine is an effective Swertiamarin derivative, which has anti-diabetic, antipsychotic, anti-inflammatory, hypotensive, diuretic and other effects, and has t...
|
TN4038 |
Eupatolide
|
6750-25-0
|
98%
|
|
Eupatolide is isolated from the flowers of Inula japonica with anti-inflammatory activity. Eupatolide can be used in studies about TRAIL resistance in breast can...
|
TN3587 |
Capillarisin
|
56365-38-9
|
98%
|
|
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
|
TN5147 |
Tilifodiolide
|
126724-95-6
|
98%
|
|
Tilifodiolide exerts in vitro and in vivo anti-inflammatory activity and in vivo antinociceptive effects. Tilifodiolide exerted antidiarrheal activity by decreas...
|
TMA1777 |
Hydrangenol 8-O-glucoside
|
67600-94-6
|
98%
|
|
Hydrangenol 8-O-glucoside may have anti-inflammary activity.
|