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Search Result

Search Results for "rats"

Compounds

Cat No. Product Name
T8441 Lerisetron 5-HT Receptor
Lerisetron 是5-HT3拮抗剂，与 5-HT3受体具有高亲和力(pKi:9.2)。它对尿烷麻醉大鼠的 5-HT 引发的反射性心率过缓具有抑制作用。
T1752 NS6180 Potassium Channel
NS6180是一种高效的KCa3.1离子通道选择性抑制剂，IC50值9nM。NS6180阻止T 细胞活化和炎症反应。
T3474 RO 46-8443 Endothelin Receptor
Ro 46-844 是选择性非肽内皮素受体拮抗剂。它对ETB(IC50: 34-69 nM) 的选择性比ETA 受体 (IC50: 6800 nM) 高的100倍以上。
T35317 Zopolrestat 唑泊司他,CP 73850,CP73850,Zopolrestatum,CP-73850 Reductase
Zopolrestat 是口服有效的醛糖还原酶抑制剂，IC50为3.1 nM。Zopolrestat 在糖尿病并发症方面有研究的价值。
T2626 SBC-115076 SBC115076 Serine/threonin kinase , Others
SBC115076 是前蛋白转化酶枯草杆菌蛋白酶/ kexin 9型(PCSK9)抑制剂。其中PCSK9 是一种前蛋白转化酶，在 LDL 受体代谢中的重要物质。
T5194 SPHINX31 Serine/threonin kinase
SPHINX31 是丝氨酸/富含精氨酸的蛋白激酶1的选择性抑制剂，其IC50值为 5.9 nM。它有效抑制丝氨酸/丰富精氨酸的剪接因子1 磷酸化，有用于局部新生血管性眼病的研究潜力。
T3046 BMY 7378 dihydrochloride BMY7378 HCl 5-HT Receptor , Dopamine Receptor , Adrenergic Receptor
BMY 7378 dihydrochloride 是选择性 α1D 肾上腺素受体拮抗剂，也是5-HT1A 受体部分激动剂。它同表达克隆大鼠 α1D-AR 的膜结合的亲和力 (Ki=2 nM)  是同克隆大鼠 α1A-AR (Ki=800 n...
T0293 Metyrapone NSC-25265,Su-4885,美替拉酮,甲吡酮 Autophagy , Dehydrogenase , P450 , Others
Metyrapone 是 STEROID 11-BETA-MONOOXYGENASE 酶抑制剂。 它被用作库欣综合征诊断中下丘脑-垂体反馈机制的测试。
T0096 Vardenafil 伐地那非,Levitra,Vivanza,Vardenafil hydrochloride PDE
Vardenafil 是选择性、高效的、具有口服活性的磷酸二酯酶5抑制剂，IC50=0.7 nM。它能够非竞争性地抑制环磷酸鸟苷水解，从而提高 cGMP 水平。它对 PDE1 (180 nM)，PDE6 (11 nM)，PDE2，PDE3，...
T23044 N,N'-Dicyclohexylurea N,N-二环己脲,Dicyclohexylurea,Dicyclohexylcarbodiamide,NSC 17013,AURORA KA-3582,1,3-Dicyclohexylurea,DCU Epoxide Hydrolase
N,N'-Dicyclohexylurea 是一种可溶性环氧化物水解酶 (sEH) 抑制剂。
T5329 Trandolapril Angiotensin-converting Enzyme (ACE)
Trandolapril 是 Trandolaprilat 的前体药物。Trandolapril 是一种口服血管紧张素转换酶抑制剂，在高血压和充血性心力衰竭及心肌梗死领域有研究价值。
T29112 VPC171 VPC-171,VPC 171,(2-氨基-4-(3-(三氟甲基)苯基)噻吩-3-基)(苯基)甲酮 Adenosine Receptor
VPC171 是一种新型腺苷 A1 受体正变构调节剂 (PAM)。
T0031L Ziprasidone hydrochloride 盐酸齐拉西酮,齐拉西酮盐酸盐,Ziprasidone HCl,CP-88059,CP-88059 hydrochloride 5-HT Receptor , Norepinephrine , Dopamine Receptor , Histamine Receptor , Adrenergic Receptor
Ziprasidone hydrochloride 是一种联合 5-HT（5-羟色胺）和多巴胺受体拮抗剂，具有抗精神病活性的强效作用。它也是去甲肾上腺素再摄取抑制剂。
T26010 Quinacainol RP 54272,RP-54272,PK10139,PK 10139,PK-10139 Others
Quinacainol是一种新的抗心律失常化合物，在大鼠中具有I类抗心律失常作用。
T36520 COR659 Cannabinoid Receptor , GABA Receptor
COR659 是一种有效的 GABAB 的阳性变构调节剂。COR659具有缓解大鼠对酒精和巧克力成瘾的作用。
T16329 Nitroflurbiprofen NO-flurbiprofen,Nitroxybutyl flurbiprofen,HCT 1206,硝基氟比洛芬 COX
Nitroflurbiprofen 是一种释放 NO 的环氧合酶抑制剂，可调节门脉高压性肝硬化大鼠肝内血管张力的增加。
T4097 Vardenafil hydrochloride trihydrate 盐酸瓦地那非三水合物,BAY38-9456,Vardenafil HCl Trihydrate PDE
Vardenafil hydrochloride trihydrate 是一种新型 PDE 抑制剂，对 PDE5 和 PDE1 的 IC50 分别为 0.7 和 180 nM。
T5628 P-cumylphenol Others
p-cumylphenol 可治疗新生大鼠肾小管囊肿形成。
T3875 CLINODISIDE A Others
Clinodiside A 是来自中草药Clinopodium chinensis 中。
T37637 4,4-Dimethoxy-2-butanone Endogenous Metabolite
4,4-Dimethoxy-2-butanone 对大鼠实验中显示出亚急性口服毒性。
Lerisetron
T8441
synonym:
Target:
NS6180
T1752
synonym:
Target:
RO 46-8443
T3474
synonym:
Target:
Zopolrestat
T35317
synonym: 唑泊司他,CP 73850,CP73850,Zopolrestatum,CP-73850
Target:
SBC-115076
T2626
synonym: SBC115076
Target:
SPHINX31
T5194
synonym:
Target:
BMY 7378 dihydrochloride
T3046
synonym: BMY7378 HCl
Target:
Metyrapone
T0293
synonym: NSC-25265,Su-4885,美替拉酮,甲吡酮
Target:
Vardenafil
T0096
synonym: 伐地那非,Levitra,Vivanza,Vardenafil hydrochloride
Target:
N,N'-Dicyclohexylurea
T23044
synonym: N,N-二环己脲,Dicyclohexylurea,Dicyclohexylcarbodiamide,NSC 17013,AURORA KA-3582,1,3-Dicyclohexylurea,DCU
Target:
Trandolapril
T5329
synonym:
Target:
VPC171
T29112
synonym: VPC-171,VPC 171,(2-氨基-4-(3-(三氟甲基)苯基)噻吩-3-基)(苯基)甲酮
Target:
Ziprasidone hydrochloride
T0031L
synonym: 盐酸齐拉西酮,齐拉西酮盐酸盐,Ziprasidone HCl,CP-88059,CP-88059 hydrochloride
Target:
Quinacainol
T26010
synonym: RP 54272,RP-54272,PK10139,PK 10139,PK-10139
Target:
COR659
T36520
synonym:
Target:
Nitroflurbiprofen
T16329
synonym: NO-flurbiprofen,Nitroxybutyl flurbiprofen,HCT 1206,硝基氟比洛芬
Target:
Vardenafil hydrochloride trihydrate
T4097
synonym: 盐酸瓦地那非三水合物,BAY38-9456,Vardenafil HCl Trihydrate
Target:
p-cumylphenol
T5628
synonym:
Target:
CLINODISIDE A
T3875
synonym:
Target:
4,4-Dimethoxy-2-butanone
T37637
synonym:
Target:
1 2 3 4 5 ... 30
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