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Search Results for " cholesterol "

Targets

278

Compounds

107

Natural Products

124

Recombinant Proteins

2

Libraries

Cat No. Product Name Synonyms Targets
T35973 Cholesterol-5α,6α-epoxide Epoxycholesterol,5α,6α-epoxy Cholestanol,NSC 18176 Others
Cholesterol-5α,6α-epoxide (Epoxycholesterol) is the metabolite of cholesterol produced by oxidation. Cholesterol-5α,6α-epoxide induces triacylglycerol biosynthesis by binding to LXRβ following tamoxifen and PBPE applicat...
T35977 6α-hydroxy Cholesterol 6α-hydroxy Cholesterol,6α-OHC
6α-hydroxy Cholesterol is an oxysterol that increases superoxide anion production in SK-N-BE cells when used at concentrations of 50 and 100 μM.[1]
T36130 22(S)-hydroxy Cholesterol 22(S)-hydroxy Cholesterol,22β-hydroxy Cholesterol
22(S)-hydroxy Cholesterol is a synthetic oxysterol and a modulator of the liver X receptor (LXR). [1] t prevents monocyte chemoattractant protein 1 (MCP-1) expression induced by the LXR agonist GW 3965 in primary hepatoc...
T36998 7β,27-dihydroxy Cholesterol 7β,27-DHC,7β,27-dihydroxy Cholesterol
7β,27-dihydroxy Cholesterol is an oxysterol and agonist of retinoic acid receptor-related orphan receptor γ (RORγ) and RORγt. [1] It activates RORγ- or RORγt-dependent signaling with EC50 values of 691 and 1,045 nM, res...
T67509 Cholesteryl Hemisuccinate Cholesterol hydrogen succinate Apoptosis , DNA/RNA Synthesis , Topoisomerase
Cholesteryl Hemisuccinate (Cholesterol hydrogen succinate) is a highly soluble cholesterol analogue often used in polar solutions for its hepatoprotective, anticancer and tumour growth inhibiting properties. Cholesteryl ...
T41008 BODIPY-Cholesterol BCh2
BODIPY-Cholesterol (TF-Chol) is a cholesterol analog with a fluorescent BODIPY motif and cellular permeability, and is a novel BODIPY cholesterol probe.BODIPY-Cholesterol can be used to study intracellular sterol uptake ...
T36217 19-hydroxy Cholesterol
19-hydroxy Cholesterol is formed during metabolic oxidation of cholesterol. It has been used as an internal standard for the quantitative determination of sterols by mass spectroscopic analysis.[1]
T65554 cholesterol-absorption inhibitor Intermediate 2 Others
cholesterol-absorption inhibitor Intermediate 2 is a potent and orally active cholesterol absorption inhibitor that reduces blood cholesterol levels.
T40140 Zanamivir-Cholesterol Conjugate
Zanamivir-cholesterol conjugate is an extended-duration neuraminidase inhibitor highly effective against drug-resistant influenza strains.
T38045 Cholesterol β-D-Glucoside
Cholesterol β-D-glucoside is a derivative of cholesterol that contains β-D-glucose . It is formed from cholesterol and glucosylceramide by β-glucosidase 1. It activates heat shock transcription factor 1 (Hsf1) in respons...
T21530 4β-hydroxy Cholesterol
4β-hydroxy Cholesterol is a useful organic compound for research related to life sciences. The catalog number is T21530 and the CAS number is 17320-10-4.
T35236 5α-Hydroxy-6-keto cholesterol YS 64,Yakkasterone
Yakkasterone is a major metabolite of cholesterol formed during exposure of lung epithelial cells to ozone.
T76139 Cholesterol esterase
Cholesterol esterase is an enzyme that hydrolyzes cholesterol ester to cholesterol and free fatty acid in the intestinal lumen. Cholesterol synthesized in the acinar cells and is stored in zymogen granules. Cholesterol e...
T76128 Cholesterol oxidase
Cholesterol oxidase (ChOx) is a bacterial flavin oxidase containing FAD, commonly used in biochemical research. Cholesterol oxidase catalyzes the oxidation of the C(3)-OH group of cholesterol (and other sterols) to chole...
T77231 Cholesterol nervonate
Cholesterol nervonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
T65073 Cholesterol n-Octanoate
Cholesterol n-Octanoate is a useful organic compound for research related to life sciences. The catalog number is T65073 and the CAS number is 1182-42-9.
T35941 DC-Chol hydrochloride ​Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride,DC-Chol (hydrochloride),DC-Cholesterol hydrochloride,​Cholesteryl 3β-N-(dimethylaminoethyl)carbamate Beta Amyloid
DC-Chol hydrochloride(DC-Cholesterol hydrochloride) inhibited the formation of Aβ40 fibrils under appropriate experimental conditions and significantly inhibited amyloid formation from oxidized hCT in a dose-dependent ma...
T60796 Cholesterol 24-hydroxylase-IN-1
Cholesterol 24-hydroxylase-IN-1 (compound 17) is a potent, orally active, and highly selective inhibitor of cholesterol 24-hydroxylase (CH24H or CYP46A1) with IC50 of 8.5 nM that can cross blood-brain barrier [1].
T77270 Cholesterol-PEG-Folate (MW 2000)
Cholesterol-PEG-Folate (MW 2000) is an excipient and can be used for the preparation of folate-conjugated PEG-liposomes [1] .
T82731 Cholesterol 24-hydroxylase-IN-2
Cholesterol 24-hydroxylase-IN-2 is a potent inhibitor of cholesterol 24-hydroxylase (CH24H or CYP46A1), exhibiting an IC50 value of 5.4 nM, and has potential applications in mammalian imaging of this enzyme [1].
T38056 Cholesteryl Arachidate Cholesterol Arachidate
Cholesteryl arachidate is a cholesterol ester that has been found in human meibum.[1][2] It has been used as an internal standard for the quantification of fatty acids in B. napus.[3]
T35321 Zymostenol delta(8)-Cholestenol,5a-Cholest-8-en-3b-ol,Δ8-Cholesterol Endogenous Metabolite , ROR
Zymostenol (5a-Cholest-8-en-3b-ol) is a RORγ agonist with an EC50 of 1 μM.Zymostenol is a late stage precursor of cholesterol biosynthesis.
T14933 Cetaben Others
Cetaben is a PPARα-independent peroxisome proliferator and is a non-fibrate hypolipidemic drug. It potent reduces the concentration of cholesterol and triglycerides.
T14362 AY 9944 Others
AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme (IC50=13 nM). At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomera...
T7482 3-chloro-5-hydroxybenzoic Acid GPR
3-chloro-5-hydroxy Benzoic Acid (3-chloro-5-hydroxy BA) is an agonist of GPR81 (EC50 : 16 μM)
T4039 BIBB 515 Others
BIBB 515 is a selective and potent inhibitor of OSC in vivo with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. 2, 3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of...
T4524 SBC-110736 SBC110736 Others , Serine/threonin kinase
SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor
T27478 GSK3987 Liver X Receptor
GSK3987 is an LXR ligand. GSK3987 recruits the steroid receptor coactivator-1 to human LXRalpha and LXRbeta with EC50s of 40 nM.
T3283 Cetilistat ATL-962 Lipid
Cetilistat (ATL-962) is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of obesity and associated co-morbidities, including type 2 diabetes.
T23521 VULM 1457 Acyltransferase
VULM 1457 is a potent ACAT inhibitor. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes. VULM1457 significantly reduces production and secretion of...
T6048 Dalcetrapib JTT-705,RO4607381 CETP
Dalcetrapib (RO4607381), a rhCETP inhibitor (IC50=0.2 μM), increases the plasma HDL cholesterol.
T23550 YM-750 YM 750 Acyltransferase
YM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC50=0.18 μM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A.
T8937 Soticlestat TAK-935,OV935 P450
Soticlestat (OV935) is a potent, selective and orally active cholesterol 24-hydroxylase (CYP46A1) inhibitor. It has the potential for epilepsy syndromes research.
T26296 Triparanol MER-29,NSC 65345,NSC-65345,NSC65345 Apoptosis , Hedgehog/Smoothened
Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1, leading to down-regulation of Hedgehog signaling. Triparan...
T2499 Torcetrapib CP-529414 CETP
Torcetrapib (CP-529414) is a cholesteryl ester transfer protein (CETP) inhibitor that reduces the heterotypic transfer of cholesteryl ester from HDL to LDL and/or VLDL. Torcetrapib failed in phase III trials due to exces...
T1676 Rosuvastatin ZD 4522 Potassium Channel , HMG-CoA Reductase , Autophagy
Rosuvastatin (ZD 4522) is an antilipemic agent that competitively inhibits hydroxymethyl-glutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting...
T1199 Mitotane Mitotan,o,p'-DDD,NCI-C04933,2,4′-DDD Apoptosis , AChR
Mitotane (NCI-C04933) is a derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors a...
T1510 Rosuvastatin calcium ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium Potassium Channel , HMG-CoA Reductase , Autophagy
Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic activity.
T38996 4α-Methylcholesterol
4α-Methylcholesterol, a derivative of Cholesterol, possesses the ability to oxidize 3-hydroxy steroid at an apparent K m of 12.6 μM.
T71756 24(S),25-Epoxycholesterol
24(S),25-Epoxycholesterol is an oxysterol agonist of the liver X receptor.
T77264 Thiocholesterol
Thiocholesterol is a member of the class of cholesteric liquid crystals (CLCs) that can be used to synthesis cationic lipid. Thiocholesterol is a stronger stabilizer of silver nanoparticles (SNPs). Thiocholesterol can be...
T62893 SM-2470
SM-2470 is an anti-hypertensive agent and an α1-adrenoceptor antagonist that exhibits sympathetic effects in anaesthetized rats. SM-2470 inhibits cholesterol lysis and reduces cholesterol absorption associated with chole...
T67835 LKM38
LKM38, a novel diazolidinyl cholesterol probe, is a promising cholesterol mimetic.LKM38 both maintains cholesterol-resistant cell growth and appropriately regulates key cholesterol homeostatic pathways.LKM38 can be a pow...
T19239 Cicloxilic acid Cycloxilic acid Others
Cicloxilic acid(Cycloxilic acid) has choleretic activity and inhibits biliary cholesterol output.
T1593 Ezetimibe SCH 58235 Others , Nrf2 , NPC1L1 , Autophagy
Ezetimibe (SCH 58235) is a Dietary Cholesterol Absorption Inhibitor. The physiologic effect of ezetimibe is by means of Decreased Cholesterol Absorption.
T68042 CHF-4227 Chf4227,Chf 4227 Estrogen Receptor/ERR
CHF-4227 is a novel, potent and selective estrogen receptor modulator that reduces cholesterol and LDL cholesterol concentrations.
T19861 Niceritrol Perycit,Cardiolipol,Bufor Others
Niceritrol (Cardiolipol) is a niacin ester that reduces cholesterol and triglycerides in total plasma and in the VLD and LD lipoprotein fractions.
T11386L Gemcabene PD-72953 Others
Gemcabene (PD-72953) is a lipid-lowering agent with anti-inflammatory activity. Gemcabene lowers low-density lipoprotein cholesterol and triglycerides, raises high-density lipoprotein cholesterol, and decreases pro-infla...
T1928 Anacetrapib MK-0859 CETP
Anacetrapib (MK-0859) (MK0859) is an effective, specific, reversible rhCETP and mutant CETP(C13S) inhibitor (IC50: 7.9 nM and 11.8 nM). Anacetrapib reduces the transfer of cholesteryl ester from HDL to LDL and/or VLDL th...
T4179 Probucol disuccinate LDL
Probucol is an anti-hyperlipidemic drug initially developed in the treatment of coronary artery disease by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.

Compounds

Cholesterol-5α,6α-epoxide
T35973
Synonym: Epoxycholesterol,5α,6α-epoxy Cholestanol,NSC 18176
Target: Others
6α-hydroxy Cholesterol
T35977
Synonym: 6α-hydroxy Cholesterol,6α-OHC
Target:
22(S)-hydroxy Cholesterol
T36130
Synonym: 22(S)-hydroxy Cholesterol,22β-hydroxy Cholesterol
Target:
7β,27-dihydroxy Cholesterol
T36998
Synonym: 7β,27-DHC,7β,27-dihydroxy Cholesterol
Target:
Cholesteryl Hemisuccinate
T67509
Synonym: Cholesterol hydrogen succinate
Target: Apoptosis, DNA/RNA Synthesis, Topoisomerase
BODIPY-Cholesterol
T41008
Synonym: BCh2
Target:
19-hydroxy Cholesterol
T36217
Synonym:
Target:
cholesterol-absorption inhibitor Intermediate 2
T65554
Synonym:
Target: Others
Zanamivir-Cholesterol Conjugate
T40140
Synonym:
Target:
Cholesterol β-D-Glucoside
T38045
Synonym:
Target:
4β-hydroxy Cholesterol
T21530
Synonym:
Target:
5α-Hydroxy-6-keto cholesterol
T35236
Synonym: YS 64,Yakkasterone
Target:
Cholesterol esterase
T76139
Synonym:
Target:
Cholesterol oxidase
T76128
Synonym:
Target:
Cholesterol nervonate
T77231
Synonym:
Target:
Cholesterol n-Octanoate
T65073
Synonym:
Target:
DC-Chol hydrochloride
T35941
Synonym: ​Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride,DC-Chol (hydrochloride),DC-Cholesterol hydrochloride,​Cholesteryl 3β-N-(dimethylaminoethyl)carbamate
Target: Beta Amyloid
Cholesterol 24-hydroxylase-IN-1
T60796
Synonym:
Target:
Cholesterol-PEG-Folate (MW 2000)
T77270
Synonym:
Target:
Cholesterol 24-hydroxylase-IN-2
T82731
Synonym:
Target:
Cholesteryl Arachidate
T38056
Synonym: Cholesterol Arachidate
Target:
Zymostenol
T35321
Synonym: delta(8)-Cholestenol,5a-Cholest-8-en-3b-ol,Δ8-Cholesterol
Target: Endogenous Metabolite, ROR
Cetaben
T14933
Synonym:
Target: Others
AY 9944
T14362
Synonym:
Target: Others
3-chloro-5-hydroxybenzoic Acid
T7482
Synonym:
Target: GPR
BIBB 515
T4039
Synonym:
Target: Others
SBC-110736
T4524
Synonym: SBC110736
Target: Others, Serine/threonin kinase
GSK3987
T27478
Synonym:
Target: Liver X Receptor
Cetilistat
T3283
Synonym: ATL-962
Target: Lipid
VULM 1457
T23521
Synonym:
Target: Acyltransferase
Dalcetrapib
T6048
Synonym: JTT-705,RO4607381
Target: CETP
YM-750
T23550
Synonym: YM 750
Target: Acyltransferase
Soticlestat
T8937
Synonym: TAK-935,OV935
Target: P450
Triparanol
T26296
Synonym: MER-29,NSC 65345,NSC-65345,NSC65345
Target: Apoptosis, Hedgehog/Smoothened
Torcetrapib
T2499
Synonym: CP-529414
Target: CETP
Rosuvastatin
T1676
Synonym: ZD 4522
Target: Potassium Channel, HMG-CoA Reductase, Autophagy
Mitotane
T1199
Synonym: Mitotan,o,p'-DDD,NCI-C04933,2,4′-DDD
Target: Apoptosis, AChR
Rosuvastatin calcium
T1510
Synonym: ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium
Target: Potassium Channel, HMG-CoA Reductase, Autophagy
4α-Methylcholesterol
T38996
Synonym:
Target:
24(S),25-Epoxycholesterol
T71756
Synonym:
Target:
Thiocholesterol
T77264
Synonym:
Target:
SM-2470
T62893
Synonym:
Target:
LKM38
T67835
Synonym:
Target:
Cicloxilic acid
T19239
Synonym: Cycloxilic acid
Target: Others
Ezetimibe
T1593
Synonym: SCH 58235
Target: Others, Nrf2, NPC1L1, Autophagy
CHF-4227
T68042
Synonym: Chf4227,Chf 4227
Target: Estrogen Receptor/ERR
Niceritrol
T19861
Synonym: Perycit,Cardiolipol,Bufor
Target: Others
Gemcabene
T11386L
Synonym: PD-72953
Target: Others
Anacetrapib
T1928
Synonym: MK-0859
Target: CETP
Probucol disuccinate
T4179
Synonym:
Target: LDL
1 2 3 4 5 6
Cat No. Product Name Synonyms Targets
T0760 Cholesterol Cholesterin,Cholesteryl alcohol Estrogen Receptor/ERR , MRP , Endogenous Metabolite , ROR
Cholesterol (Cholesteryl alcohol) is the primary sterol in mammals. The significance of Cholesterol is becoming more appreciated in fundamental cellular processes.
T8040 Cholesterol myristate Cholesteryl myristate,Cholesteryl tetradecanoate Others , Potassium Channel , GABA Receptor , Endogenous Metabolite , AChR
Cholesterol myristate (Cholesteryl myristate) is a natural steroid present in traditional Chinese medicine. Cholesterol myristate binds to several ion channels such as GABAA receptor, the nicotinic acetylcholine receptor...
T10805 Cholesterol glucuronide Others
Cholesterol glucuronide is an endogenous metabolite of lipid generated by UDP glucuonyltransferase in the liver.
T2918 Cholesteryl Acetate Cholesterin acetate,Cholesterol acetate,Acebrochol Others
Cholesteryl Acetate is a natural product for research related to life sciences. The catalog number is T2918 and the CAS number is 604-35-3.
TQ0274 27-Hydroxycholesterol 25(R)-27-hydroxy Cholesterol Estrogen/progestogen Receptor , Liver X Receptor
27-Hydroxycholesterol (25(R)-27-hydroxy Cholesterol) is a selective modulator of estrogen receptor and an agonist of the liver X receptor.
T19237 Cholesteryl oleate Oleoylcholesterol,Cholesterol Oleate,Cholesteryl cis-9-octadecenoate Endogenous Metabolite
Cholesteryl oleate (Cholesteryl cis-9-octadecenoate) is a cholesteryl ester. Cholesteryl oleate can be used to synthesize solid lipid nanoparticles which is a nanoparticle-based gene therapy approach.
T5239 Cholesteryl sulfate sodium Cholesterol 3-Sulfate Sodium Salt,Sodium Cholesteryl Sulfate Endogenous Metabolite , PKC
Cholesteryl sulfate sodium (Sodium Cholesteryl Sulfate) is a sterol sulfate in human plasma. Cholesteryl sulfate sodium is a component of cell membrane and has a regulatory function. Cholesteryl sulfate sodium also activ...
T19236 Cholesteryl behenate Cholesteryl docosanoate,Cholesterol behenate Others
Cholesteryl behenate is a standard in electrospray ionization tandem mass spectrometry for the analysis of cholesteryl esters and cholesterol.
T2721 Digitonin Others
Digitonin is a natural product of the glycoside family and is a detergent. Digitonin has antitumor activity, binds to cholesterol molecules to increase the permeability of cell membranes, and is active in the cleavage of...
T8192 Pentacosanoic acid Others , Endogenous Metabolite
Pentacosanoic acid, belongs to the class of organic compounds known as very long-chain fatty acids.
T8153 Glycohyodeoxycholic acid Others , Endogenous Metabolite
glycohyodeoxycholic acid is a major metabolite of the secondary bile acid hyodeoxycholic acid in humans.
T5214 Cholesteryl linoleate CE(18:2(9Z,12Z)),Cholesterol Linoleate,Linoleic Acid cholesteryl ester Others , Endogenous Metabolite
Cholesteryl linoleate (Linoleic Acid cholesteryl ester) is a cholesterol ester found in LDL. Cholesteryl linoleate is transferred to the plasma membrane of macrophages and CHO cells expressing 15-lipoxygenase (15-LO) via...
T19161 7α-Hydroxycholesterol Others
7α-Hydroxycholesterol is a cholesterol oxide formed by both enzymatic and non-enzymatic oxidation. It can be used as a biomarker for lipid peroxidation.
TN2082 Pinostrobin Beta Amyloid , IL Receptor , Serine/threonin kinase , TNF
Pinostrobin, a potent flavonoid inducer, exerts a neuroprotective effect against Aα²(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting oxidative damage and calcium overload, as well as suppress...
T5S0246 Pseudoprotodioscin 山药 Others , Fatty Acid Synthase
1. Pseudoprotodioscin has moderate cytotoxicity.
T2963 Cholic Acid Cholanic acid,Cholate,Colalin Endogenous Metabolite
Cholic Acid (Cholate) is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. Cholic acid facilitates fat absorption and cholesterol excretion.
T4537 Cholic acid sodium SodiumCholate HIV Protease , Endogenous Metabolite
Cholic acid sodium (SodiumCholate) exhibits a strong spermicidal and antiviral [anti-human immunodeficiency virus (HIV)-1] activity.
TMS2180 Zeaxanthin Anchovyxanthin,All-Trans-Zeaxanthin Antioxidant , Endogenous Metabolite
1. Lutein and Zeaxanthin (All-Trans-Zeaxanthin) in neural tissue may have biological effects that include antioxidation, anti-inflammation, and structural actions. 2. Lutein and Zeaxanthin may be protective against eye d...
T2744 Methyl Cholate Cholic acid methyl ester Others
Methyl Cholate (Cholic acid methyl ester) is the methyl form of cholic acid. Cholic acid is a major bile acid produced by the liver and synthesized from cholesterol.
T0687 Simvastatin MK-0733,MK 733 Apoptosis , Mitophagy , Ferroptosis , HMG-CoA Reductase , Autophagy
Simvastatin (MK 733) is a HMG-CoA Reductase Inhibitor. The mechanism of action of simvastatin is as a Hydroxymethylglutaryl-CoA Reductase Inhibitor.
TN1576 Diallyl disulfide IL Receptor , NOS , NF-κB
Diallyl disulfide has antitumor effect, the effect can be enhanced by miR-200b and miR-22.
T13522 7-Ketolithocholic acid 3α-Hydroxy-7-oxo-5β-cholanic acid Endogenous Metabolite
7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid) (3α-Hydroxy-7-oxo-5β-cholanic acid) is capable of absorption and serves to suppress the production of endogenous bile acid and the secretion of biliary cholester...
T4970 LANOSTEROL 3β-Hydroxy-8,24-lanostadiene,8,24-Lanostadien-3β-ol Endogenous Metabolite
Lanosterol (3β-Hydroxy-8,24-lanostadiene) is a tetracyclic triterpenoid which is the compound from which all steroids are derived.
TN6714 Geranylgeraniol FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,CJ-24095 Apoptosis
Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice. Geranylgeraniol (FT0626663) inhibits growth and induces apoptosis of various tumor cells. Geranylgeraniol (FT0626663) ...
TN6715 7-Ketocholesterol Others
7-Ketocholesterol is a metabolite of Cholesterol
T4717 25-Hydroxycholesterol Others , Endogenous Metabolite , HMG-CoA Reductase
25-Hydroxycholesterol is a steroid derivative that suppresses the cleavage of sterol regulatory element binding proteins (SREBPs). It inhibits HMG-CoA reductase and so it also plays a significant role in the in vivo regu...
T4923 7-Dehydrocholesterol Provitamin D3,7-DHC Endogenous Metabolite
7-Dehydrocholesterol (Provitamin D3) down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts.
T10085 20(S)-Hydroxycholesterol 20α-Hydroxycholesterol Smo
20(S)-Hydroxycholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo).
T10086 24-Hydroxycholesterol Cholest-5-ene-3beta,24-diol Liver X Receptor , NMDAR
24-Hydroxycholesterol (Cholest-5-ene-3beta,24-diol) is an oxysterol compound that is an activator of the n-methyl-d-aspartate receptor (NMDA) and the transcription factor LXR, which has been used in the study of cardioge...
T29329 24-Methylenecholesterol 24Methylenecholesterol,24 Methylenecholesterol,Chalinasterol,Ostreasterol Acyltransferase
24-Methylenecholesterol (24 Methylenecholesterol) is a natural marine sterol, which stimulates cholesterol acyl transferase (ACAT) in human macrophages.
TN1338 7Beta-Hydroxycholesterol LDL , Calcium Channel , MAPK
7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells.
T14063 7α,25-Dihydroxycholesterol 7α,25-OHC EBI2/GPR183 , Endogenous Metabolite
7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cel...
T75515 7β,25-Dihydroxycholesterol
7β,25-Dihydroxycholesterol is an endogenous metabolite and is found to act as chemoattractants for immune cells expressing EBI2 [1] .
T19164 8-Dehydrocholesterol Others
8-Dehydrocholesterol is a compound whose elevated concentration is a diagnostic biochemical hallmark of classical Smith-Lemli-Opitz syndrome.
T15720 Lathosterol Endogenous Metabolite
Lathosterol is a cholesterol-like molecule. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis.
T21383 D-Thyroxine Dethyrona,Detyroxin,Dextroid,Dextrothyroxine;Biotirmone,Dextroxin,Biotirmone,Debetrol,Dextrothyroxine Others
D-Thyroxine (Dextroxin) could lower cholesterol and also increases hepatic lipase which in turn improves utilization of triglycerides, leading to improve apolipoprotein E cholesterol particles.
TN1474 Caulilexin C Others , Antifungal
Caulilexin C shows inhibitory activity on human Acyl CoA: cholesterol transferase I (hACATI) and on human Acyl CoA: cholesterol transferase 2 (hACAT2) at 100 mug/ml.
T5074 Cholesteryl palmitate Others , Endogenous Metabolite
Cholesteryl palmitic acid is a cholesteryl ester. A cholesteryl ester is an ester of cholesterol. Fatty acid esters of cholesterol constitute about two-thirds of the cholesterol in the plasma. Cholesterol is a sterol (a ...
T5238 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine 1,2-Dipalmitoyl-sn-glycero-3-PE,1,2-Dipalmitoyl-sn-glycerol-3-Phosphoethanolamine,1,2-DPPE Others , Endogenous Metabolite
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE), a phospholipid member of the glycerophosphonoethanolamine family, is a major component in biological membranes. Studies focused on interactions between DPPE and ch...
T3771 Methyl protodioscin Smilax saponin B,NSC-698790 Apoptosis
Methyl protodioscin (Smilax saponin B) potentially increase HDL cholesterol while reducing LDL cholesterol and triglycerides. Methyl protodioscin has antitumor property. Methyl protodioscin induced apoptotic process in h...
T1207 Lovastatin MK-803,Mevinolin Ferroptosis , HMG-CoA Reductase , Autophagy
Lovastatin (MK-803) is an HMG-CoA Reductase Inhibitor, used for lowering cholesterol.
T4S2157 Campesterol (24R)-5-Ergosten-3β-ol Endogenous Metabolite
Campesterol ((24R)-5-Ergosten-3β-ol) is a plant sterol with cholesterol lowering and anticarcinogenic effects, it and other plant sterols often decrease LDL cholesterol levels overall. Campesterol has anti-inflammatory e...
T19711 Desmosterol Desmesterol,24-Dehydrocholesterol Endogenous Metabolite
Desmosterol (24-Dehydrocholesterol) is a cholesterol biosynthesis intermediate that inhibits macrophage inflammatory vesicle activation and prevents vascular inflammation and atherosclerosis.
T1664 Meglutol Dicrotalic acid,3-Hydroxy-3-methylglutaric acid Endogenous Metabolite , HMG-CoA Reductase , Autophagy
Meglutol (3-Hydroxy-3-methylglutaric acid) is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conve...
T8165 Erythrodiol Endogenous Metabolite , ABC
Erythrodiol, an olive oil component, promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein.
T0254 Probucol DH-581 Virus Protease , ABC , Lipid
Probucol (DH-581), an anti-hyperlipidemic drug, can lower the level of cholesterol in the bloodstream by increasing the LDL catabolic rate.
T8301 Amaranth Acid Red 27 Others
Amaranth (Acid Red 27) as a potential component of lifestyle modification to improve cardiovascular risk profiles by modifying cardiovascular risk factors such as cholesterol, diabetes, and hypertension.
T19085 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC POPC,1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine,Palmitoyloleoylphosphatidylcholine Others
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (Palmitoyloleoylphosphatidylcholine) is a phospholipid ubiquitous in cell membranes, with compositions in the range 0-60 mol% cholesterol.
T3761 1-Octacosanol n-Octacosanol,Montanyl alcohol,Cluytyl alcohol,Octacosanol,Octacosyl alcohol,Octanosol Others
1-Octacosanol (Octanosol) is a straight-chain aliphatic 28-carbon primary fatty alcohol that is used as a nutritional supplement. It is reported to possess cholesterol-lowering effects, antiaggregatory properties, cytopr...
T0851 Pregnenolone 3β-Hydroxy-5-pregnen-20-one,Arthenolone Cannabinoid Receptor , Endogenous Metabolite , TRP/TRPV Channel , AChR , Autophagy
Pregnenolone (Arthenolone) is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer's disease.
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Natural Products

Cholesterol
T0760
Synonym: Cholesterin,Cholesteryl alcohol
Target: Estrogen Receptor/ERR, MRP, Endogenous Metabolite, ROR
Cholesterol myristate
T8040
Synonym: Cholesteryl myristate,Cholesteryl tetradecanoate
Target: Others, Potassium Channel, GABA Receptor, Endogenous Metabolite, AChR
Cholesterol glucuronide
T10805
Synonym:
Target: Others
Cholesteryl Acetate
T2918
Synonym: Cholesterin acetate,Cholesterol acetate,Acebrochol
Target: Others
27-Hydroxycholesterol
TQ0274
Synonym: 25(R)-27-hydroxy Cholesterol
Target: Estrogen/progestogen Receptor, Liver X Receptor
Cholesteryl oleate
T19237
Synonym: Oleoylcholesterol,Cholesterol Oleate,Cholesteryl cis-9-octadecenoate
Target: Endogenous Metabolite
Cholesteryl sulfate sodium
T5239
Synonym: Cholesterol 3-Sulfate Sodium Salt,Sodium Cholesteryl Sulfate
Target: Endogenous Metabolite, PKC
Cholesteryl behenate
T19236
Synonym: Cholesteryl docosanoate,Cholesterol behenate
Target: Others
Digitonin
T2721
Synonym:
Target: Others
Pentacosanoic acid
T8192
Synonym:
Target: Others, Endogenous Metabolite
glycohyodeoxycholic acid
T8153
Synonym:
Target: Others, Endogenous Metabolite
Cholesteryl linoleate
T5214
Synonym: CE(18:2(9Z,12Z)),Cholesterol Linoleate,Linoleic Acid cholesteryl ester
Target: Others, Endogenous Metabolite
7α-Hydroxycholesterol
T19161
Synonym:
Target: Others
Pinostrobin
TN2082
Synonym:
Target: Beta Amyloid, IL Receptor, Serine/threonin kinase, TNF
Pseudoprotodioscin
T5S0246
Synonym: 山药
Target: Others, Fatty Acid Synthase
Cholic Acid
T2963
Synonym: Cholanic acid,Cholate,Colalin
Target: Endogenous Metabolite
Cholic acid sodium
T4537
Synonym: SodiumCholate
Target: HIV Protease, Endogenous Metabolite
Zeaxanthin
TMS2180
Synonym: Anchovyxanthin,All-Trans-Zeaxanthin
Target: Antioxidant, Endogenous Metabolite
Methyl Cholate
T2744
Synonym: Cholic acid methyl ester
Target: Others
Simvastatin
T0687
Synonym: MK-0733,MK 733
Target: Apoptosis, Mitophagy, Ferroptosis, HMG-CoA Reductase, Autophagy
Diallyl disulfide
TN1576
Synonym:
Target: IL Receptor, NOS, NF-κB
7-Ketolithocholic acid
T13522
Synonym: 3α-Hydroxy-7-oxo-5β-cholanic acid
Target: Endogenous Metabolite
LANOSTEROL
T4970
Synonym: 3β-Hydroxy-8,24-lanostadiene,8,24-Lanostadien-3β-ol
Target: Endogenous Metabolite
Geranylgeraniol
TN6714
Synonym: FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,CJ-24095
Target: Apoptosis
7-Ketocholesterol
TN6715
Synonym:
Target: Others
25-Hydroxycholesterol
T4717
Synonym:
Target: Others, Endogenous Metabolite, HMG-CoA Reductase
7-Dehydrocholesterol
T4923
Synonym: Provitamin D3,7-DHC
Target: Endogenous Metabolite
20(S)-Hydroxycholesterol
T10085
Synonym: 20α-Hydroxycholesterol
Target: Smo
24-Hydroxycholesterol
T10086
Synonym: Cholest-5-ene-3beta,24-diol
Target: Liver X Receptor, NMDAR
24-Methylenecholesterol
T29329
Synonym: 24Methylenecholesterol,24 Methylenecholesterol,Chalinasterol,Ostreasterol
Target: Acyltransferase
7Beta-Hydroxycholesterol
TN1338
Synonym:
Target: LDL, Calcium Channel, MAPK
7α,25-Dihydroxycholesterol
T14063
Synonym: 7α,25-OHC
Target: EBI2/GPR183, Endogenous Metabolite
7β,25-Dihydroxycholesterol
T75515
Synonym:
Target:
8-Dehydrocholesterol
T19164
Synonym:
Target: Others
Lathosterol
T15720
Synonym:
Target: Endogenous Metabolite
D-Thyroxine
T21383
Synonym: Dethyrona,Detyroxin,Dextroid,Dextrothyroxine;Biotirmone,Dextroxin,Biotirmone,Debetrol,Dextrothyroxine
Target: Others
Caulilexin C
TN1474
Synonym:
Target: Others, Antifungal
Cholesteryl palmitate
T5074
Synonym:
Target: Others, Endogenous Metabolite
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
T5238
Synonym: 1,2-Dipalmitoyl-sn-glycero-3-PE,1,2-Dipalmitoyl-sn-glycerol-3-Phosphoethanolamine,1,2-DPPE
Target: Others, Endogenous Metabolite
Methyl protodioscin
T3771
Synonym: Smilax saponin B,NSC-698790
Target: Apoptosis
Lovastatin
T1207
Synonym: MK-803,Mevinolin
Target: Ferroptosis, HMG-CoA Reductase, Autophagy
Campesterol
T4S2157
Synonym: (24R)-5-Ergosten-3β-ol
Target: Endogenous Metabolite
Desmosterol
T19711
Synonym: Desmesterol,24-Dehydrocholesterol
Target: Endogenous Metabolite
Meglutol
T1664
Synonym: Dicrotalic acid,3-Hydroxy-3-methylglutaric acid
Target: Endogenous Metabolite, HMG-CoA Reductase, Autophagy
Erythrodiol
T8165
Synonym:
Target: Endogenous Metabolite, ABC
Probucol
T0254
Synonym: DH-581
Target: Virus Protease, ABC, Lipid
Amaranth
T8301
Synonym: Acid Red 27
Target: Others
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC
T19085
Synonym: POPC,1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine,Palmitoyloleoylphosphatidylcholine
Target: Others
1-Octacosanol
T3761
Synonym: n-Octacosanol,Montanyl alcohol,Cluytyl alcohol,Octacosanol,Octacosyl alcohol,Octanosol
Target: Others
Pregnenolone
T0851
Synonym: 3β-Hydroxy-5-pregnen-20-one,Arthenolone
Target: Cannabinoid Receptor, Endogenous Metabolite, TRP/TRPV Channel, AChR, Autophagy

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00055 LCAT Protein, Human, Recombinant (His) Human HEK293
Lecithin: cholesterol acyltransferase (LCAT) is the sole enzyme that esterifies cholesterol in plasma, thus determining the maturation of high-density lipoproteins. Because it maintains an unesterified cholesterol gradie...
TMPY-02899 Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (His) Mouse HEK293
Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and...
TMPY-01081 SR-BI/SCARB1 Protein, Human, Recombinant (His) Human HEK293
Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localiz...
TMPY-00989 LDLR Protein, Human, Recombinant (His) Human HEK293
LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved i...
TMPH-00007 HMGCR Protein, Human, Recombinant (His) Human E. coli
The production of this recombinant Human HMGCR protein is just like all recombinant proteins. The process involved transfecting E.coli cells with DNA vector containing the template of recombinant DNA. The E.coli cells co...
TMPY-00408 PCSK9 Protein, Human, Recombinant (D374Y & V474I & G670E, His) Human HEK293
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPY-05131 PCSK9 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPY-02956 Apolipoprotein L/APOL1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
APOL1, also known as apolipoprotein L1, is a minor apoprotein component of HDL (High-density lipoprotein) or 'good cholesterol' which is synthesized in the liver and also in many other tissues, including pancreas, kidney...
TMPY-04966 PCSK9 Protein, Human, Recombinant (D374Y, His) Human HEK293
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPY-00915 Serpin A1 Protein, Human, Recombinant (His) Human HEK293
SerpinA1, also known as Alpha-1 antitrypsin (AAT), is a prototype member of the Serpin superfamily of the serine protease inhibitors. This serine protease inhibitor blocks the protease, neutrophil elastase. Alpha-1 antit...
TMPY-01114 NPC2 Protein, Human, Recombinant (His) Human HEK293
Niemann-Pick Type C2 (NPC2) plays an important role in the regulation of intracellular cholesterol homeostasis via direct binding with free cholesterol. NPC2 is an intralysosomal protein that binds cholesterol in vitro. ...
TMPH-03593 Pneumolysin Protein, S. pneumoniae serotype 4, Recombinant (Avi & His) Streptococcus pneumoniae E. coli
A cholesterol-dependent toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertio...
TMPH-03244 Anionic trypsin-2 Protein, Rat, Recombinant (His) Rat Yeast
A cholesterol-dependent toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertio...
TMPK-00835 LCAT Protein, Mouse, Recombinant (His) Mouse HEK293
Lecithin:cholesterol acyltransferase (LCAT) is the only enzyme capable of esterifying cholesterol in plasma, thus determining the maturation of high-density lipoproteins. Because it maintains an unesterified cholesterol ...
TMPY-00264 NPC2 Protein, Rat, Recombinant (His) Rat HEK293
Niemann-Pick Type C2 (NPC2) plays an important role in the regulation of intracellular cholesterol homeostasis via direct binding with free cholesterol. NPC2 is an intralysosomal protein that binds cholesterol in vitro. ...
TMPY-01097 SR-BI/SCARB1 Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localiz...
TMPY-04990 NPC2 Protein, Mouse, Recombinant (His) Mouse HEK293
Niemann-Pick Type C2 (NPC2) plays an important role in the regulation of intracellular cholesterol homeostasis via direct binding with free cholesterol. NPC2 is an intralysosomal protein that binds cholesterol in vitro. ...
TMPK-01291 ANXA1 Protein, Cynomolgus, Recombinant (His) Cynomolgus E. coli
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ...
TMPH-03245 BCL2 Protein, Rat, Recombinant (His) Rat in vitro E. coli expression system
A cholesterol-dependent toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertio...
TMPY-03428 Apolipoprotein A-I/APOA1 Protein, Human, Recombinant (His) Human E. coli
Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and...
TMPY-05498 SR-BI/SCARB1 Protein, Human, Recombinant (hFc) Human HEK293
Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localiz...
TMPH-03592 Pneumolysin Protein, S. pneumoniae serotype 4, Recombinant (His) Streptococcus pneumoniae Yeast
A cholesterol-dependent toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertio...
TMPK-00799 ANXA1 Protein, Mouse, Recombinant (His) Mouse E. coli
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ...
TMPH-01460 HNRNPA1 Protein, Human, Recombinant (His) Human E. coli
Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the tu...
TMPH-02080 PRSS56 Protein, Human, Recombinant (His & Myc) Human E. coli
May accelerate cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis. May orchestrate hematopoietic stem and progenitor cell emergence from the hemogenic endotheli...
TMPH-00764 Trypsin-1 Protein, Gadus morhua, Recombinant (His) Gadus morhua E. coli
May play a role in lipid transport protein in Schwann cells. May bind cholesterol.
TMPY-01098 SR-BI/SCARB1 Protein, Mouse, Recombinant (His) Mouse HEK293
Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localiz...
TMPY-06955 Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and...
TMPK-00768 ANXA1 Protein, Human, Recombinant (His) Human E. coli
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ...
TMPH-02228 TRA2B Protein, Human, Recombinant (His & Myc) Human Baculovirus
Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol ...
TMPY-02553 Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (aa 1-264, hFc) Mouse HEK293
Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and...
TMPY-00667 Apolipoprotein A-I/APOA1 Protein, Human, Recombinant (hFc) Human HEK293
Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and...
TMPY-05499 LDLR Protein, Human, Recombinant (His), Biotinylated Human HEK293
LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved i...
TMPY-01014 LDLR Protein, Mouse, Recombinant (His) Mouse HEK293
LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved i...
TMPY-05323 LDLR Protein, Human, Recombinant (mFc) Human HEK293
LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved i...
TMPH-01461 HNRNPA3 Protein, Human, Recombinant (His & Myc) Human E. coli
Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the tu...
TMPH-00001 CD133/PROM1 Protein-VLP, Human, Recombinant (His) Human HEK293
May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epit...
TMPH-03605 CHOD Protein, Streptomyces sp., Recombinant (GST) Streptomyces sp. E. coli
Bifunctional enzyme that catalyzes the oxidation of the 3-beta-hydroxy group of cholesterol and the isomerization of the double bond of the resulting product.
TMPH-03257 CPS1 Protein, Rat, Recombinant (His & Myc) Rat E. coli
Bifunctional enzyme that catalyzes the oxidation of the 3-beta-hydroxy group of cholesterol and the isomerization of the double bond of the resulting product.
TMPH-02661 Frataxin/FXN Protein, Mouse, Recombinant (E. coli, His) Mouse E. coli
Contributes to various developmental events and other processes such as wound healing and cholesterol homeostasis through its interactions with multiple signaling pathways. Wnt signaling inhibitor which competes with WNT...
TMPY-04767 PMVK Protein, Human, Recombinant (His) Human E. coli
PMVK is a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level a...
TMPY-05809 LDLR Protein, Human, Recombinant (193D/A, His) Human HEK293
LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved i...
TMPY-05348 LDLR Protein, Mouse, Recombinant (His), Biotinylated Mouse HEK293
LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved i...
TMPH-01462 HNRNPH1 Protein, Human, Recombinant (GST) Human E. coli
Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol.
TMPJ-00158 Apolipoprotein A-I/APOA1 Protein, Human, Recombinant Human E. coli
Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various...
TMPH-02556 PLA2G5 Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epit...
TMPH-00457 Dac g 4 Protein, Dactylis glomerata, Recombinant (His) Dactylis glomerata E. coli
May function as inhibitor of dietary triglyceride digestion. Lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters (in vitro).
TMPH-01463 HNRNPL Protein, Human, Recombinant (His & SUMO) Human E. coli
Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol.
TMPJ-00369 PCSK9 Protein, Human, Recombinant (His & HA & Avi), Biotinylated Human Human Cells
Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processi...
TMPH-01444 Human herpesvirus 1 (HHV-1) (strain 17) ICP47 protein (His) HHV-1 E. coli
Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens prote...
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LCAT Protein, Human, Recombinant (His)
TMPY-00055
Species: Human
Expression System: HEK293
Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (His)
TMPY-02899
Species: Mouse
Expression System: HEK293
SR-BI/SCARB1 Protein, Human, Recombinant (His)
TMPY-01081
Species: Human
Expression System: HEK293
LDLR Protein, Human, Recombinant (His)
TMPY-00989
Species: Human
Expression System: HEK293
HMGCR Protein, Human, Recombinant (His)
TMPH-00007
Species: Human
Expression System: E. coli
PCSK9 Protein, Human, Recombinant (D374Y & V474I & G670E, His)
TMPY-00408
Species: Human
Expression System: HEK293
PCSK9 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-05131
Species: Human
Expression System: HEK293
Apolipoprotein L/APOL1 Protein, Human, Recombinant (His)
TMPY-02956
Species: Human
Expression System: Baculovirus-Insect Cells
PCSK9 Protein, Human, Recombinant (D374Y, His)
TMPY-04966
Species: Human
Expression System: HEK293
Serpin A1 Protein, Human, Recombinant (His)
TMPY-00915
Species: Human
Expression System: HEK293
NPC2 Protein, Human, Recombinant (His)
TMPY-01114
Species: Human
Expression System: HEK293
Pneumolysin Protein, S. pneumoniae serotype 4, Recombinant (Avi & His)
TMPH-03593
Species: Streptococcus pneumoniae
Expression System: E. coli
Anionic trypsin-2 Protein, Rat, Recombinant (His)
TMPH-03244
Species: Rat
Expression System: Yeast
LCAT Protein, Mouse, Recombinant (His)
TMPK-00835
Species: Mouse
Expression System: HEK293
NPC2 Protein, Rat, Recombinant (His)
TMPY-00264
Species: Rat
Expression System: HEK293
SR-BI/SCARB1 Protein, Mouse, Recombinant (His & hFc)
TMPY-01097
Species: Mouse
Expression System: HEK293
NPC2 Protein, Mouse, Recombinant (His)
TMPY-04990
Species: Mouse
Expression System: HEK293
ANXA1 Protein, Cynomolgus, Recombinant (His)
TMPK-01291
Species: Cynomolgus
Expression System: E. coli
BCL2 Protein, Rat, Recombinant (His)
TMPH-03245
Species: Rat
Expression System: in vitro E. coli expression system
Apolipoprotein A-I/APOA1 Protein, Human, Recombinant (His)
TMPY-03428
Species: Human
Expression System: E. coli
SR-BI/SCARB1 Protein, Human, Recombinant (hFc)
TMPY-05498
Species: Human
Expression System: HEK293
Pneumolysin Protein, S. pneumoniae serotype 4, Recombinant (His)
TMPH-03592
Species: Streptococcus pneumoniae
Expression System: Yeast
ANXA1 Protein, Mouse, Recombinant (His)
TMPK-00799
Species: Mouse
Expression System: E. coli
HNRNPA1 Protein, Human, Recombinant (His)
TMPH-01460
Species: Human
Expression System: E. coli
PRSS56 Protein, Human, Recombinant (His & Myc)
TMPH-02080
Species: Human
Expression System: E. coli
Trypsin-1 Protein, Gadus morhua, Recombinant (His)
TMPH-00764
Species: Gadus morhua
Expression System: E. coli
SR-BI/SCARB1 Protein, Mouse, Recombinant (His)
TMPY-01098
Species: Mouse
Expression System: HEK293
Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (hFc)
TMPY-06955
Species: Mouse
Expression System: HEK293
ANXA1 Protein, Human, Recombinant (His)
TMPK-00768
Species: Human
Expression System: E. coli
TRA2B Protein, Human, Recombinant (His & Myc)
TMPH-02228
Species: Human
Expression System: Baculovirus
Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (aa 1-264, hFc)
TMPY-02553
Species: Mouse
Expression System: HEK293
Apolipoprotein A-I/APOA1 Protein, Human, Recombinant (hFc)
TMPY-00667
Species: Human
Expression System: HEK293
LDLR Protein, Human, Recombinant (His), Biotinylated
TMPY-05499
Species: Human
Expression System: HEK293
LDLR Protein, Mouse, Recombinant (His)
TMPY-01014
Species: Mouse
Expression System: HEK293
LDLR Protein, Human, Recombinant (mFc)
TMPY-05323
Species: Human
Expression System: HEK293
HNRNPA3 Protein, Human, Recombinant (His & Myc)
TMPH-01461
Species: Human
Expression System: E. coli
CD133/PROM1 Protein-VLP, Human, Recombinant (His)
TMPH-00001
Species: Human
Expression System: HEK293
CHOD Protein, Streptomyces sp., Recombinant (GST)
TMPH-03605
Species: Streptomyces sp.
Expression System: E. coli
CPS1 Protein, Rat, Recombinant (His & Myc)
TMPH-03257
Species: Rat
Expression System: E. coli
Frataxin/FXN Protein, Mouse, Recombinant (E. coli, His)
TMPH-02661
Species: Mouse
Expression System: E. coli
PMVK Protein, Human, Recombinant (His)
TMPY-04767
Species: Human
Expression System: E. coli
LDLR Protein, Human, Recombinant (193D/A, His)
TMPY-05809
Species: Human
Expression System: HEK293
LDLR Protein, Mouse, Recombinant (His), Biotinylated
TMPY-05348
Species: Mouse
Expression System: HEK293
HNRNPH1 Protein, Human, Recombinant (GST)
TMPH-01462
Species: Human
Expression System: E. coli
Apolipoprotein A-I/APOA1 Protein, Human, Recombinant
TMPJ-00158
Species: Human
Expression System: E. coli
PLA2G5 Protein, Mouse, Recombinant (His & SUMO)
TMPH-02556
Species: Mouse
Expression System: E. coli
Dac g 4 Protein, Dactylis glomerata, Recombinant (His)
TMPH-00457
Species: Dactylis glomerata
Expression System: E. coli
HNRNPL Protein, Human, Recombinant (His & SUMO)
TMPH-01463
Species: Human
Expression System: E. coli
PCSK9 Protein, Human, Recombinant (His & HA & Avi), Biotinylated
TMPJ-00369
Species: Human
Expression System: Human Cells
Human herpesvirus 1 (HHV-1) (strain 17) ICP47 protein (His)
TMPH-01444
Species: HHV-1
Expression System: E. coli
Cat No. Product Name
L2501 Human Endogenous Metabolite Compound Library Plus

1300 compounds
A unique collection of 1300 endogenous metabolism-related compounds for research in endogenous metabolism-related diseases and drug screening.
L5100 Fluorochemical Library

583 compounds
A unique collection of 583 fluorochemicals that can be used for high through-put screening (HTS) and high content screening (HCS);
TargetMol