MicroRNA

MicroRNAs (miRNAs) are a class of endogenous non-coding RNAs, about 22 nucleotides in length, that regulate gene expression by inhibiting the translation of mRNAs or decreasing their stability. miRNAs can act as oncogenes or tumor suppressor genes, and by using miRNA mimics or anti-miRNAs to modulate specific miRNA changes, it is possible to restore gene regulatory networks and signaling pathways, and even reverse the phenotype of cancer cells. Compared with traditional small molecule drugs, miRNAs have the natural property of regulating multiple target genes and are located at the center of multi-target regulatory networks.