T3021 |
Bulleyaconitine A
|
107668-79-1
|
98.72%
|
|
Bulleyaconitine A, an analgesic and antiinflammatory drug isolated from Aconitum plants, has several potential targets, such as voltage-gated Na+ channels.
|
T0037 |
Halazone
|
80-13-7
|
90%
|
|
Halazone is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.
|
TN3910 |
Ecdysone
|
3604-87-3
|
100%
|
|
Ecdysone signaling through Ecdysone receptor isoform B1 is required cell autonomously for the muscle death. A nctional Bombyx Ecdysone receptor binds to EcRE-D a...
|
T6782 |
Benzocaine hydrochloride
|
23239-88-5
|
|
|
Benzocaine hydrochloride is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.
|
T3029 |
Sparteine sulfate
|
299-39-8
|
|
|
Sparteine sulfate is a class 1a antiarrhythmic agent and a sodium channel blocker. It can chelate the bivalents calcium and magnesium.
|
TN3042 |
4-Hydroxycinnamamide
|
194940-15-3
|
98%
|
|
4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
|
T2173 |
Veratridine
|
71-62-5
|
98%
|
|
Veratridine is a benzoate-cevane found in Veratrum and Schoenocaulon. It activates sodium channels to stay open longer than normal.
|
T22829 |
GX-674
|
1432913-36-4
|
98%
|
|
GX-674 is a highly potent and selective voltage-gated sodium channel 1.7 (Nav1.7) antagonist with an IC50 value of 0.1 nM measured at -40 mV for the study of inf...
|
TP1852 |
Myomodulin
|
110570-93-9
|
98%
|
|
Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.Myomodulin is present in two identified aplysia neurons that contain myomodulin A the A...
|
TN4697 |
Odoroside H
|
18810-25-8
|
98%
|
|
Odoroside H has anticancer activities, the cytotoxic effects are induced by the inhibition of the plasma membrane bound Na(+)/K(+)-ATPase.
|
TN5141 |
Thevetin B
|
27127-79-3
|
98%
|
|
Thevetin B is a cardiac glycoside and an inhibitor of Na+-, K+-dependent adenosinetriphosphatase (Na+,K+-ATPase) from Thevetia peruviana.
|
TCA2511 |
11Beta-hydroxyprogesterone
|
600-57-7
|
98%
|
|
The progesterone derivatives 11 alpha- and 11 beta-hydroxyprogesterone are potent inhibitors of 11 beta-hydroxysteroid dehydrogenase (isoforms 1 and 2) in vitro ...
|
TN4276 |
Isocudraniaxanthone B
|
199851-52-0
|
98%
|
|
Isocudraniaxanthone B may have antimalarial activity.
|
T12951 |
Sodium Channel inhibitor 2
|
653573-60-5
|
98%
|
|
Sodium Channel inhibitor 2 is a blocker of sodium channel.
|
TN5234 |
Vindorosine
|
5231-60-7
|
98%
|
|
Vindorosine has blood vessel relaxation effect, possible underlying mechanisms involving the inhibition of Ca(2+) entry via L-type Ca(2+) channels in vascular sm...
|
T16887 |
Sipatrigine
|
130800-90-7
|
98%
|
|
Sipatrigine is a glutamate release inhibitor and voltage-dependent sodium channel.
|
TN2306 |
Wilfordine
|
37239-51-3
|
98%
|
|
Wilfordine is an insecticidally active alkaloid, Na+-K+-ATPase may be an acting target of wilfordine against some larvae of insect.
|
TN5060 |
Stauntosaponin A
|
1417887-91-2
|
98%
|
|
Stauntosaponin A and stauntosaponin B show moderate inhibitory activities against Na+/K+-ATPase with IC50 values of 21 and 29 uM, respectively.
|
TN4183 |
Hardwickiic acid
|
1782-65-6
|
98%
|
|
Hardwickiic acid is a natural compound derived from Pulicaria gnaphalodes and is an anti-injury receptor compound. hardwickiic acid blocks tetrodotoxin-sensitive...
|
T13830 |
Propoxycaine hydrochloride
|
550-83-4
|
98%
|
|
Propoxycaine hydrochloride is an inhibit of voltage-gated sodium channels.
|