esterase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T76139	Cholesterol esterase
	Cholesterol esterase, also known as bile salt-stimulated lipase and carboxyl ester lipase, is an enzyme responsible for hydrolyzing cholesterol ester into cholesterol and free fatty acid within the intestinal lumen. This...
T15082	DDAO		Others
	DDAO is a promising near-infrared (NIR) red fluorescent probe with long emission wavelength (λem = 656 nm) and tunable excitation wavelength (600-650 nm). It can de desiged for detection of the activities of different en...		Others
T0157	Roxatidine Acetate hydrochloride	HOE 760,Roxatidine Acetate HCl	Histamine Receptor
	Roxatidine Acetate hydrochloride (HOE 760) is a specific and competitive histamin H2-receptor antagonist. It inhibits gastric acid secretion and ulcer formation.		Histamine Receptor
T18894	5(6)-CFDA	CFDA,5-(6)-Carboxyfluorescein diacetate	Others
	5(6)-CFDA (5-(6)-Carboxyfluorescein diacetate) is a cell-permeant esterase substrate that can serve as a viability probe that measures both enzymatic activities, which is required to activate its fluorescence, and cell-m...		Others
T77524	Carboxylesterase-IN-2		Wnt/beta-catenin , Lipid
	Carboxylesterase-IN-2 is a potent Carboxylesterase Notum inhibitor (IC50 <= 10 nM).Carboxylesterase-IN-2 has potential for the study of cancer diseases.		Wnt/beta-catenin , Lipid
T60057	Notum pectinacetylesterase-1		Others
	Notum pectinacetylesterase-1 is a Notum Pectinacetylesterase inhibitor with IC50 < 0.025 μM.		Others
T60788	Carboxylesterase-IN-3		Wnt/beta-catenin , Lipid
	Carboxylesterase-IN-3 is a potent inhibitor of Carboxylesterase Notum (IC50 ≤ 10 nM).Carboxylesterase-IN-3 has the potential to study cancer diseases.		Wnt/beta-catenin , Lipid
T76130	Acetylcholinesterase
	Acetylcholinesterase (ACHE; EC 3.1.1.7) is a cholinergic enzyme mainly found in neuromuscular junctions and cholinergic type chemical synapses, and is often used in biochemical research. Acetylcholinesterase catalyzes th...
T76133	Phosphodiesterase II
	Phosphodiesterase 2 (II), a key enzyme prominently involved in the hydrolysis of vital second messengers, cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), is frequently utilized in biochem...
T76123	Carboxylesterase
	Carboxylesterases (CESs), carboxylate hydrolases broadly distributed in nature and prevalent in mammalian liver, play a significant role in biochemical research. These enzymes facilitate the hydrolysis of diverse substra...
T76138	Phosphodiesterase
	Phosphodiesterase (PDE), an enzyme capable of catalyzing the hydrolysis of the 3' ring phosphate bond in cyclic nucleotides, plays a crucial role in biochemical research and acts as a vital regulator in signal transducti...
T40237	Carboxylesterase-IN-1
	Carboxylesterase-IN-1, a novel pesticide, acts as an inhibitor of carboxylesterase at a concentration of 50 μg/mL, displaying comparable inhibitory activity to the established inhibitor triphenyl phosphate.
T63015	Pancreatic lipase/Carboxylesterase 1-IN-1
	Pancreatic lipase/Carboxylesterase 1-IN-1 (Compound 39) is a potent, dual inhibitor of pancreatic lipase (PL) and human carboxylesterase 1A (hCES1A), acting on PL (IC50: 2.13 μM) and hCES1A (IC50: 0.055 μM).
T76156	Sphingomyelin phosphodiesterase
	Sphingomyelin phosphodiesterase, a hydrolase, plays a crucial role in sphingomyelin metabolism by catalyzing the conversion of sphingomyelin into phosphocholine and ceramide. Furthermore, it is instrumental in cellular d...
T36018	Phosphodiesterase 4 Inhibitor
	Phosphodiesterase 4 (PDE4) inhibitor is an inhibitor of PDE4 with an IC50 value of 0.10 μM for the human recombinant enzyme.
T5943	4,4'-DIMETHOXYBENZIL	p-Anisil	Others
	4,4'-Dimethoxybenzil (p-Anisil) is a human intestinal carboxyl esterase (hiCE) inhibitor( Ki : 70 nM).		Others
T18880	BCDA	5-bromo-4-chloroindoxyl acetate	Others
	BCDA (5-bromo-4-chloroindoxyl acetate) is a chromogenic substrate of esterase. It is used to detect the activity of esterase.		Others
TN3820	Demethoxydeacetoxypseudolaric acid B		Others
	Demethoxydeacetoxypseudolaric acid B's the metabolic reaction of TDA in vivo is mainly occurred in blood and contributes to be the hydrolysis of plasma esterase to ester bond, as well as the glucosylation reaction.		Others
T19323	Fluorescein diacetate	3,6-Diacetoxyfluoran,Di-O-acetylfluorescein	Others
	Fluorescein diacetate (Di-O-acetylfluorescein) is a cell permeable esterase-substrate for hGSTP1-1.		Others
T17028	Tefinostat	CHR-2845	HDAC
	Tefinostat (CHR-2845) is a potent monocyte/macrophage-targeted histone deacetylase (HDAC) inhibitor. Tefinostat is cleaved to the active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1).Tefino...		HDAC