Search Result

Search Results for " chemokine "

Targets

CCR

144

Compounds

Natural Products

250

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T11481	GSK2239633A		CCR
	GSK2239633A is an allosteric antagonist of CC-chemokine receptor 4 (CCR4) with a pIC50 of 7.96 for the binding of [125I]-TARC to human CCR4.		CCR
T10297L	AMG 487		CXCR
	AMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively.		CXCR
T30258	AZD-4818	CCR1 antagonist	CCR
	AZD-4818 (CCR1 antagonist) is a chemokine CCR1 antagonist for the treatment of chronic obstructive pulmonary disease.		CCR
T4300	AZD2098		CCR
	AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor used for asthma research.		CCR
T7499	TAK-779	Takeda 779	HIV Protease , CXCR , CCR
	TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).		HIV Protease , CXCR , CCR
TQ0103	INCB3344		CCR
	INCB3344 is an effective, specific and orally bioavailable CCR2 antagonist with IC50 values of 9.5 nM (mCCR2) and 5.1 nM (hCCR2) in binding antagonism and 7.8 nM (mCCR2) and in 3.8 nM (hCCR2) antagonism of chemotaxis act...		CCR
T5849	JMS-17-2		CXCR
	JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM).		CXCR
T4674	SB297006	SB 297006	CCR
	SB297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ. It is at least 250-fold selective for CCR3 over a panel of ...		CCR
T17225	Vercirnon	CCX282-B,GSK-1605786,Traficet-EN	CCR
	Vercirnon (Traficet-EN) is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.		CCR
T7681	AZD-5069		CXCR
	AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).		CXCR
T3047	SRT3109		CXCR
	SRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.		CXCR
T1955	SB225002		CXCR
	SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.		CXCR
T5384	RS 504393		CCR
	RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1).		CCR
TQ0283	RS102895		CCR
	RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.		CCR
T1739	WZ811		CXCR
	WZ811 is a novel and effective small molecular CXCR4 antagonist (EC50: 0.3 nM).		CXCR
T4163	Reparixin	DF 1681Y,Repertaxin	CXCR
	Reparixin (Repertaxin) is a potent inhibitor of both CXCL8 receptors CXCR1/2, it inhibits weakly CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks CXCR1-mediated chemotaxis (IC50=1 nM).		CXCR
T3992	MSX-122	MSX 122,MSX122	CXCR
	MSX-122 is a novel small molecule and partial CXCR4 antagonist, with potent inhibition of CXCR4/CXCL12 actions(IC50 = 10 nM).		CXCR
T5193	Danirixin	GSK1325756	CXCR
	Danirixin (GSK1325756) is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).		CXCR
T17208	USL311		CXCR
	USL311 is a CXCR4 receptor antagonist which prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4. USL311 inhibits CXCR4 activation and decreases proliferation and migration of CXCR4-expressing...		CXCR
T2477	UNBS5162	UNBS 5162,UNBS-5162	CXCR , Autophagy
	UNBS5162 (UNBS-5162) is a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers.		CXCR , Autophagy
T24700	R243	R 243,R-243	CCR
	R243 is CCR8 signaling and chemotaxis inhibitor.		CCR
T9721	ML339		CXCR
	ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.		CXCR
T4033	MSX-130	MSX 130	CXCR
	MSX-130 is CXCR4 Antagonist.		CXCR
T4032	MSX-127	MSX 127	CXCR
	MSX-127 elicites positive response in peptide CXCR4.		CXCR
T16111	ML604086		CCR
	ML604086 suppresses CCL1 mediated chemotaxis and enhances intracellular Ca2 concentrations. ML604086 is a selective inhibitor of CCR8. It also inhibiting CCL1 binding to CCR8 on circulating T-cells.		CCR
T10425	AZ084		CCR
	AZ084 is a potent, selective, allosteric, and oral active CCR8 antagonist (Ki: 0.9 nM). It has the potential to treat asthma.		CCR
T16091	MK-0812 Succinate		Others , CCR
	MK-0812 Succinate is an effective and selective CCR2 antagonist. It also has a high affinity at CCR2.		Others , CCR
TQ0174	Mavorixafor	AMD-070	CXCR
	Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding. Mavorixafor inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells (IC...		CXCR
T3430	PF-4136309	INCB8761,PF 4136309	CCR
	PF-4136309 (INCB8761) is a specific, effective, and orally bioavailable CCR2 antagonist.		CCR
T11699	J-113863		CCR
	J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-α receptor...		CCR
T83712	Interleukin-8 (54-72) (human) TFA	IL-8 (54-72),C-X-C Motif Chemokine Ligand (54-72),CXCL8 (54-72)
	Interleukin-8 (IL-8) (54-72), a peptide comprising amino acids 54-72 from the mature IL-8 sequence and 81-99 from the pre-processed form, inhibits the flow-based adhesion of primary human neutrophils to human umbilical v...
T8497	SX-682		CXCR
	SX-682 is a potent, selective and orally bioavailable inhibitor of CXCR1/2 ,has the potential to treat castration-resistant prostate cancer.		CXCR
T4584	BMS-813160	BMS 813160	CCR
	BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular.		CCR
T16850	SB-265610	GSK-CXCR2	CXCR
	SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis (IC50s: 3.7 nM and...		CXCR
T12773	RS102895 hydrochloride		Others , 5-HT Receptor , CCR
	RS102895 hydrochloride is a potent antagonist of CCR2(IC50 of 360 nM).		Others , 5-HT Receptor , CCR
T2375	BX471	BX 471,BX-471,ZK-811752	CCR
	BX471 (BX 471) is a potent, selective non-peptide CCR1 antagonist.		CCR
T7130	Navarixin	MK-7123,SCH 527123	CXCR
	Navarixin (MK-7123)(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophil trafficking in animal models, characteristics that may be benef...		CXCR
T10639	C-021 dihydrochloride		CCR
	C-021 dihydrochloride is a potent CCR4 antagonist. It potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM.		CCR
T13114	CCR2 antagonist 4	Teijin compound 1	CCR
	CCR2 antagonist 4 (Teijin compound 1) is a potent and specific antagonist of CCR2(IC50s of 180 nM), and potently inhibits MCP-1-induced chemotaxis(IC50 of 24 nM).		CCR
T11179	Elubrixin	SB-656933	IL Receptor , CXCR
	Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin can be used for inflammatory diseases such as inflammatory bowel disease and airway inflammat...		IL Receptor , CXCR
T12705	Reparixin L-lysine salt	Repertaxin L-lysine salt	CXCR
	Reparixin L-lysine salt (Repertaxin L-lysine salt) is an allosteric chemokine receptor 1/2 (CXCR1/2) activation inhibitor.		CXCR
T6016	Maraviroc	Celsentri,UK-427857,Selzentry	HIV Protease , CCR
	Maraviroc (Selzentry) is a C-C Chemokine Receptor Type 5 (CCR5) antagonist, and for MIP-1α(IC50=3.3 nM), MIP-1β (IC50=7.2 nM) and RANTES(IC50=5.2 nM).Maraviroc inhibits HIV-1 entry via CCR5 coreceptor interaction.		HIV Protease , CCR
T13324	VUF11207 fumarate		CXCR , Arrestin
	VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi: 8.1).		CXCR , Arrestin
T7624	DAPTA	DAPTA(TFA),D-Ala-peptide T-amide,Adaptavir	HIV Protease , CCR
	DAPTA (Adaptavir) is an inhibitor of CCR5, shows potent anti-HIV activities.		HIV Protease , CCR
TQ0297	Cenicriviroc	TAK-652,TBR-652	HIV Protease , CCR
	Cenicriviroc (TAK-652) is an orally active, dual antagonist of CCR2/CCR5. It also inhibits both HIV-1 and HIV-2, and displays potent anti-infective and anti-inflammatory activity.		HIV Protease , CCR
T21870	C-021	4-Quinazolinamine, 2-[1,4'-bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-	CCR
	C 021 dihydrochloride is a potent CCR4 antagonist. C-021 (4-Quinazolinamine, 2-[1,4'-bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-) dihydrochloride potently inhibits functional chemotaxis in humans and mice with IC50s ...		CCR
T7208	AMD 3465 hexahydrobromide	GENZ-644494 (hexahydrobromide)	HIV Protease , CXCR
	AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity.		HIV Protease , CXCR
T14900	CCR2-RA-[R]		CCR
	CCR2-RA-[R] is a C-C chemokine receptor type 2 (CCR2) allosteric antagonist (IC50: 103 nM).		CCR
T2386	Pirfenidone	S-7701,AMR-69,S-7701,AMR69	CCR , TGF-beta/Smad
	Pirfenidone (AMR69) is an inhibitor for TGF-β production and TGF-β stimulated collagen production. Pirfenidone inhibits fibroblast, epidermal, platelet-derived, and transforming beta-1 growth factors, thereby slowing tum...		CCR , TGF-beta/Smad
T3435	Vicriviroc maleate	SCH-D (maleate),SCH-417690 (maleate)	HIV Protease , CCR
	Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus. The IC50 value is 0.91 nM in clinical development for the treatment...		HIV Protease , CCR

Compounds

Synonym: CCR1 antagonist

Target: HIV Protease, CXCR, CCR

Synonym: CCX282-B,GSK-1605786,Traficet-EN

Synonym: DF 1681Y,Repertaxin

Target: CXCR

MSX-122

T3992

Synonym: MSX 122,MSX122

Synonym: UNBS 5162,UNBS-5162

Target: CXCR, Autophagy

Synonym: INCB8761,PF 4136309

Interleukin-8 (54-72) (human) TFA

T83712

Synonym: IL-8 (54-72),C-X-C Motif Chemokine Ligand (54-72),CXCL8 (54-72)

RS102895 hydrochloride

T12773

Synonym:

Target: Others, 5-HT Receptor, CCR

BX471

T2375

Synonym: BX 471,BX-471,ZK-811752

Target: CCR

Navarixin

T7130

Synonym: MK-7123,SCH 527123

Target: CXCR

C-021 dihydrochloride

Synonym: Teijin compound 1

Target: IL Receptor, CXCR

Reparixin L-lysine salt

T12705

Synonym: Repertaxin L-lysine salt

Target: CXCR

Maraviroc

T6016

Synonym: Celsentri,UK-427857,Selzentry

Target: HIV Protease, CCR

VUF11207 fumarate

T13324

Synonym:

Target: CXCR, Arrestin

DAPTA

T7624

Synonym: DAPTA(TFA),D-Ala-peptide T-amide,Adaptavir

Target: HIV Protease, CCR

Cenicriviroc

TQ0297

Synonym: TAK-652,TBR-652

Target: HIV Protease, CCR

C-021

T21870

Synonym: 4-Quinazolinamine, 2-[1,4'-bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-

Target: CCR

AMD 3465 hexahydrobromide

T7208

Synonym: GENZ-644494 (hexahydrobromide)

Target: HIV Protease, CXCR

Synonym: S-7701,AMR-69,S-7701,AMR69

Target: CCR, TGF-beta/Smad

Vicriviroc maleate

T3435

Synonym: SCH-D (maleate),SCH-417690 (maleate)

Target: HIV Protease, CCR

Cat No.	Product Name	Synonyms	Targets
T6413	Bindarit	AF2838	CCR
	Bindarit (AF2838) displays specific inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.		CCR
T3396	Baohuoside I	Icariside-II,Icariin-II	Apoptosis , CXCR
	Baohuoside I (Icariside-II) is a component of Epimedium koreanum, exhibits anti-inflammatory activity and anti-osteoporosis activities.		Apoptosis , CXCR
TN1273	7,4'-Dihydroxyflavone	4',7-Dihydroxyflavone	NF-κB , COX , HDAC , CCR , NOD
	7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.		NF-κB , COX , HDAC , CCR , NOD
T3S1416	Decursin	Decursinol angelate,(+)-Decursin	Apoptosis , PKC
	1. Decursin (Decursinol angelate) is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug. 2. Decursin exhibits hepatoprotective effects , potentially by inhibiting the TGF-β1 ...		Apoptosis , PKC
T0617	Nicotinamide N-oxide	Nicotinamide-N-oxide,Nicotinamide 1-oxide,1-oxynicotinamide	c-Myc , Endogenous Metabolite , CXCR , Drug Metabolite
	Nicotinamide N-oxide (Nicotinamide 1-oxide) is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD+) in animals. The enzyme that catalyzes the reduction of n...		c-Myc , Endogenous Metabolite , CXCR , Drug Metabolite
TN2331	Eleutheroside B1		Influenza Virus
	Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits l...		Influenza Virus
T3426	Bacoside A		MMP , Others , TNF , Dopamine Receptor , NOS , ROS
	Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro. It exerts cytoprotective efficacy by attenuation of ROS generated through oxidat...		MMP , Others , TNF , Dopamine Receptor , NOS , ROS
TN2951	3-(hydroxymethyl)cyclopentanone		CCR
	3-Hydroxymethylcyclopentanone is a precursor to synthesize methyl epijasmonate. 3-Hydroxymethylcyclopentanone compounds, which are useful as intermediates in the preparation of HIV chemokine CCR-5 receptor antagonists.		CCR
T69446	Cochlioquinone A
	Cochlioquinone A is an inhibitor of diacylglycerol kinase (DGK) and diacylglycerol acyltransferase (DGAT). It has been shown to reduce the concentration of phosphatidic acid in T cell lymphoma and has also been shown to ...
T14063	7α,25-Dihydroxycholesterol	7α,25-OHC	EBI2/GPR183 , Endogenous Metabolite
	7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cel...		EBI2/GPR183 , Endogenous Metabolite
T37714	Fuscin
	Fuscin is a quinonoid fungal metabolite originally isolated from O. fuscum that has diverse biological activities. It inhibits binding of the ADP/ATP translocase inhibitor atractyloside to rat liver mitochondria in an AD...
TN5593	Euphohelioscopin A
	Euphohelioscopin A, an activator of protein kinase C (PKC), it inhibits proliferation and induces differentiation of the myeloid leukemia cell lines THP-1 and HL-60. Euphohelioscopin A has anti-inflammary activity, it ex...

Natural Products

Synonym: Icariside-II,Icariin-II

Target: Apoptosis, CXCR

7,4'-Dihydroxyflavone

TN1273

Synonym: 4',7-Dihydroxyflavone

Target: NF-κB, COX, HDAC, CCR, NOD

Decursin

T3S1416

Synonym: Decursinol angelate,(+)-Decursin

Target: Apoptosis, PKC

Nicotinamide N-oxide

T0617

Synonym: Nicotinamide-N-oxide,Nicotinamide 1-oxide,1-oxynicotinamide

Target: c-Myc, Endogenous Metabolite, CXCR, Drug Metabolite

Eleutheroside B1

TN2331

Synonym:

Target: Influenza Virus

Bacoside A

T3426

Synonym:

Target: MMP, Others, TNF, Dopamine Receptor, NOS, ROS

3-(hydroxymethyl)cyclopentanone

7α,25-Dihydroxycholesterol

T14063

Synonym: 7α,25-OHC

Target: EBI2/GPR183, Endogenous Metabolite

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04037	MIP-1 alpha/CCL3 Protein, Rat, Recombinant	Rat	E. coli
	CCL3 is a cytokine belonging to the CC chemokine family. Chemokines are a family of structurally related leukocyte chemoattractant cytokines that play a central role during immunoregulatory and inflammation processes. Al...
TMPY-03050	CXCL5 Protein, Human, Recombinant	Human	E. coli
	CXCL5 is a small cytokine belonging to the CXC chemokine family. CXC chemokines are particularly significant for leukocyte infiltration in inflammatory diseases. CXCL5 is produced following stimulation of cells with the ...
TMPY-05337	CXCL16 Protein, Human, Recombinant (His)	Human	HEK293
	C-X-C motif chemokine 16, also known as Small-inducible cytokine B16, SR-PSOX, and CXCL16, is a single-pass type I membrane protein which belongs to the intercrine alpha (chemokine CxC) family. CXCL16 exists in transmemb...
TMPY-02234	CXCL9 Protein, Human, Recombinant	Human	E. coli
	Chemokine (C-X-C motif) ligand 9 (CXCL9), also known as Monokine induced by gamma interferon (MIG), is a small cytokine belonging to the CXC chemokine family. The function of this chemokine has not been specifically defi...
TMPY-00695	I-309 Protein, Human, Recombinant (hFc)	Human	HEK293
	CCL1 or chemokine (C-C motif) ligand 1, also known as I-309 or TCA-3, is a member of the chemokine (C-C motif) ligand family. The C-C chemokines have two cysteines nearby the amino terminus. There have been at least 27 d...
TMPY-00740	SDF-1 Protein, Human, Recombinant (hFc)	Human	HEK293
	The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-02820	SDF-1 Protein, Human, Recombinant (isoform a)	Human	E. coli
	The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-02591	SDF-1 Protein, Human, Recombinant	Human	E. coli
	The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-03274	CXCL11 Protein, Human, Recombinant	Human	E. coli
	I-TAC, also known as CXCL11, is a small cytokine belonging to the CXC chemokine family. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low e...
TMPY-00649	MIP-1 alpha/CCL3 Protein, Human, Recombinant (His)	Human	Yeast
	CCL3 is a cytokine belonging to the CC chemokine family. Chemokines are a family of structurally related leukocyte chemoattractant cytokines that play a central role during immunoregulatory and inflammation processes. Al...
TMPY-00118	MCP-1/CCL2 Protein, Human, Recombinant (His)	Human	Yeast
	Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, belongs to a group of CC chemokines located in chromosome 17q11.2. MCP-1 protein interacts with chemokine C-C motif receptor 2 (CCR2) to activate and recruit ...
TMPY-00566	CCL18 Protein, Human, Recombinant (His)	Human	Yeast
	CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its...
TMPY-02970	CXCL10 Protein, Human, Recombinant	Human	E. coli
	(C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor couple...
TMPY-02755	Lymphotactin/XCL1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Baculovirus-Insect Cells
	This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the ...
TMPY-00754	IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99)	Human	HEK293
	Interleukin 8 (IL-8), also known as CXCL8, which is a chemokine with a defining CXC amino acid motif that was initially characterized for its leukocyte chemotactic activity, is now known to possess tumorigenic and proang...
TMPY-04726	IL-8/CXCL8 Protein, Human, Recombinant (His)	Human	Yeast
	Interleukin 8 (IL-8), also known as CXCL8, which is a chemokine with a defining CXC amino acid motif that was initially characterized for its leukocyte chemotactic activity, is now known to possess tumorigenic and proang...
TMPY-00472	IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99)	Human	E. coli
	Interleukin 8 (IL-8), also known as CXCL8, which is a chemokine with a defining CXC amino acid motif that was initially characterized for its leukocyte chemotactic activity, is now known to possess tumorigenic and proang...
TMPY-03905	Lymphotactin/XCL1 Protein, Canine, Recombinant (His)	Canine	Baculovirus-Insect Cells
	This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the ...
TMPJ-01409	CCL27 Protein, Human, Recombinant	Human	E. coli
	Human Chemokine (C-C Motif) Ligand 27 (CCL27) is a small cytokine that is a member of the CC chemokine family; it is expressed in numerous tissues, including gonads, thymus, placenta and skin. CCL27 elicits its chemotact...
TMPY-02149	BCA-1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	E. coli
	The chemokine CXCL13, also known as BCA-1 (B-cell-attracting chemokine-1) or BLC (B-lymphocyte chemoattractant), which belongs to the CXC chemokine family. CXCL13 and its receptor CXCR5 control the organization of B cell...
TMPY-03708	BCA-1 Protein, Canine, Recombinant (His)	Canine	E. coli
	The chemokine CXCL13, also known as BCA-1 (B-cell-attracting chemokine-1) or BLC (B-lymphocyte chemoattractant), which belongs to the CXC chemokine family. CXCL13 and its receptor CXCR5 control the organization of B cell...
TMPY-03897	Fractalkine Protein, Canine, Recombinant (hFc)	Canine	HEK293
	Fractalkine or Chemokine (C-X3-C motif) ligand 1 (CX3CL1) is a member of the CX3C chemokine family. Fractalkine / CX3CL1 is a unique chemokine that functions not only as a chemoattractant but also as an adhesion molecule...
TMPY-03898	Fractalkine Protein, Canine, Recombinant	Canine	HEK293
	Fractalkine or Chemokine (C-X3-C motif) ligand 1 (CX3CL1) is a member of the CX3C chemokine family. Fractalkine / CX3CL1 is a unique chemokine that functions not only as a chemoattractant but also as an adhesion molecule...
TMPY-03025	CXCL16 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	C-X-C motif chemokine 16, also known as Small-inducible cytokine B16, SR-PSOX, and CXCL16, is a single-pass type I membrane protein which belongs to the intercrine alpha (chemokine CxC) family. CXCL16 exists in transmemb...
TMPY-02184	SDF-1 Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPH-00485	CCL17 Protein, Canine, Recombinant (His & KSI)	Canine	E. coli
	CCL17 Protein, Canine, Recombinant (His & KSI) is expressed in E. coli.
TMPY-03248	TARC Protein, Rhesus, Recombinant (His)	Rhesus	Baculovirus-Insect Cells
	Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved location...
TMPY-04695	CCL4 Protein, Rat, Recombinant (His)	Rat	Yeast
	CCL4 (C-C chemokine ligand 4), is a macrophage inflammatory protein with a chief effect in inflammation and immune-regulation, and was documented in cancer progression by promoting instability in the tumor environment. T...
TMPY-04917	CCL5 Protein, Rat, Recombinant (His)	Rat	Yeast
	Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved location...
TMPY-04255	CXCL9 Protein, Rhesus, Recombinant	Rhesus	E. coli
	Chemokine (C-X-C motif) ligand 9 (CXCL9), also known as Monokine induced by gamma interferon (MIG), is a small cytokine belonging to the CXC chemokine family. The function of this chemokine has not been specifically defi...
TMPY-02415	Fractalkine Protein, Cynomolgus, Rhesus, Recombinant (hFc)	Cynomolgus,Rhesus	HEK293
	Fractalkine or Chemokine (C-X3-C motif) ligand 1 (CX3CL1) is a member of the CX3C chemokine family. Fractalkine / CX3CL1 is a unique chemokine that functions not only as a chemoattractant but also as an adhesion molecule...
TMPY-04665	Fractalkine Protein, Canine, Recombinant (His)	Canine	HEK293
	Fractalkine or Chemokine (C-X3-C motif) ligand 1 (CX3CL1) is a member of the CX3C chemokine family. Fractalkine / CX3CL1 is a unique chemokine that functions not only as a chemoattractant but also as an adhesion molecule...
TMPY-03896	CXCL16 Protein, Canine, Recombinant (hFc)	Canine	HEK293
	C-X-C motif chemokine 16, also known as Small-inducible cytokine B16, SR-PSOX, and CXCL16, is a single-pass type I membrane protein which belongs to the intercrine alpha (chemokine CxC) family. CXCL16 exists in transmemb...
TMPY-02754	CXCL16 Protein, Rat, Recombinant (His)	Rat	HEK293
	C-X-C motif chemokine 16, also known as Small-inducible cytokine B16, SR-PSOX, and CXCL16, is a single-pass type I membrane protein which belongs to the intercrine alpha (chemokine CxC) family. CXCL16 exists in transmemb...
TMPH-00990	ACKR1 Protein, Human, Recombinant (His)	Human	in vitro E. coli expression system
	ACKR1 Protein, Human, Recombinant (His) is expressed in in vitro E. coli expression system.
TMPJ-00019	CCL28 Protein, Human, Recombinant	Human	E. coli
	Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and i...
TMPJ-00018	CCL16 Protein, Human, Recombinant	Human	E. coli
	CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. CCL16 is distantly related to other CC c...
TMPY-04713	Fractalkine Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	Fractalkine or Chemokine (C-X3-C motif) ligand 1 (CX3CL1) is a member of the CX3C chemokine family. Fractalkine / CX3CL1 is a unique chemokine that functions not only as a chemoattractant but also as an adhesion molecule...
TMPY-03771	CXCL16 Protein, Canine, Recombinant (His)	Canine	HEK293
	C-X-C motif chemokine 16, also known as Small-inducible cytokine B16, SR-PSOX, and CXCL16, is a single-pass type I membrane protein which belongs to the intercrine alpha (chemokine CxC) family. CXCL16 exists in transmemb...
TMPY-03022	IL-8/CXCL8 Protein, Canine, Recombinant	Canine	E. coli
	Interleukin 8 (IL-8), also known as CXCL8, which is a chemokine with a defining CXC amino acid motif that was initially characterized for its leukocyte chemotactic activity, is now known to possess tumorigenic and proang...
TMPY-03580	SDF-1 Protein, Canine, Recombinant	Canine	E. coli
	The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-00279	Dengue virus DENV-2 (strain New Guinea C) NS5 (methyltransferase domain)/Nonstructural protein 5 Protein (His)	DENV	E. coli

TMPY-02550	Eotaxin/CCL11 Protein, Human, Recombinant (His)	Human	E. coli
	CCL11 or chemokine (C-C motif) ligand 11 is a member of the chemokine (C-C motif) ligand family. Chemokin (C-C motif) ligand 11 is a member of the chemokine family. There are four members of the chemokine family: C-C kem...
TMPY-02828	CCL21 Protein, Rhesus, Recombinant	Rhesus	Baculovirus-Insect Cells
	Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved location...
TMPJ-01060	CXCL6 Protein, Human, Recombinant (His)	Human	Human Cells
	Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. It is a potent neutrophil chemotactic and activating factor and it exhibits extensive similarity to other CXC chemokines...
TMPY-03480	IL-8/CXCL8 Protein, Rhesus, Recombinant	Rhesus	E. coli
	Interleukin 8 (IL-8), also known as CXCL8, which is a chemokine with a defining CXC amino acid motif that was initially characterized for its leukocyte chemotactic activity, is now known to possess tumorigenic and proang...
TMPH-03265	CMKLR2 Protein, Rat, Recombinant (His)	Rat	in vitro E. coli expression system
	Receptor for chemoattractant adipokine chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation and energy homesotasis. Signals mainly via beta-arrestin pathway. Binding of RARRES2 activates...
TMPK-00699	FAM19A5 Protein, Human, Recombinant (His)	Human	E. coli
	FAM19A5 is a secretory protein that is predominantly expressed in the brain. Although the FAM19A5 gene has been found to be associated with neurological and/or psychiatric diseases, only limited information is available ...
TMPY-00009	GRO beta/CXCL2 Protein, Rat, Recombinant	Rat	E. coli
	Chemokine (C-X-C motif) ligand 2 (CXCL2), also called macrophage inflammatory protein 2 (MIP-2), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2 (Gro-2), is a small cytokine belonging to the CXC chemokine fam...
TMPY-00008	CXCL1 Protein, Rat, Recombinant	Rat	E. coli
	The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimu...
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MIP-1 alpha/CCL3 Protein, Rat, Recombinant

TMPY-04037

Species: Rat

Expression System: E. coli

CXCL5 Protein, Human, Recombinant

TMPY-03050

Species: Human

Expression System: E. coli

CXCL16 Protein, Human, Recombinant (His)

TMPY-05337

Species: Human

Expression System: HEK293

CXCL9 Protein, Human, Recombinant

TMPY-02234

Species: Human

Expression System: E. coli

I-309 Protein, Human, Recombinant (hFc)

TMPY-00695

Species: Human

Expression System: HEK293

SDF-1 Protein, Human, Recombinant (hFc)

TMPY-00740

Species: Human

Expression System: HEK293

SDF-1 Protein, Human, Recombinant (isoform a)

TMPY-02820

Species: Human

Expression System: E. coli

SDF-1 Protein, Human, Recombinant

TMPY-02591

Species: Human

Expression System: E. coli

CXCL11 Protein, Human, Recombinant

TMPY-03274

Species: Human

Expression System: E. coli

MIP-1 alpha/CCL3 Protein, Human, Recombinant (His)

TMPY-00649

Species: Human

Expression System: Yeast

MCP-1/CCL2 Protein, Human, Recombinant (His)

TMPY-00118

Species: Human

Expression System: Yeast

CCL18 Protein, Human, Recombinant (His)

TMPY-00566

Species: Human

Expression System: Yeast

CXCL10 Protein, Human, Recombinant

TMPY-02970

Species: Human

Expression System: E. coli

Lymphotactin/XCL1 Protein, Cynomolgus, Recombinant (His)

TMPY-02755

Species: Cynomolgus

Expression System: Baculovirus-Insect Cells

IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99)

TMPY-00754

Species: Human

Expression System: HEK293

IL-8/CXCL8 Protein, Human, Recombinant (His)

TMPY-04726

Species: Human

Expression System: Yeast

IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99)

TMPY-00472

Species: Human

Expression System: E. coli

Lymphotactin/XCL1 Protein, Canine, Recombinant (His)

TMPY-03905

Species: Canine

Expression System: Baculovirus-Insect Cells

CCL27 Protein, Human, Recombinant

TMPJ-01409

Species: Human

Expression System: E. coli

BCA-1 Protein, Cynomolgus, Recombinant (His)

TMPY-02149

Species: Cynomolgus

Expression System: E. coli

BCA-1 Protein, Canine, Recombinant (His)

TMPY-03708

Species: Canine

Expression System: E. coli

Fractalkine Protein, Canine, Recombinant (hFc)

TMPY-03897

Species: Canine

Expression System: HEK293

Fractalkine Protein, Canine, Recombinant

TMPY-03898

Species: Canine

Expression System: HEK293

CXCL16 Protein, Rat, Recombinant (hFc)

TMPY-03025

Species: Rat

Expression System: HEK293

SDF-1 Protein, Rhesus, Recombinant (hFc)

TMPY-02184

Species: Rhesus

Expression System: HEK293

CCL17 Protein, Canine, Recombinant (His & KSI)

TMPH-00485

Species: Canine

Expression System: E. coli

TARC Protein, Rhesus, Recombinant (His)

TMPY-03248

Species: Rhesus

Expression System: Baculovirus-Insect Cells

CCL4 Protein, Rat, Recombinant (His)

TMPY-04695

Species: Rat

Expression System: Yeast

CCL5 Protein, Rat, Recombinant (His)

TMPY-04917

Species: Rat

Expression System: Yeast

CXCL9 Protein, Rhesus, Recombinant

TMPY-04255

Species: Rhesus

Expression System: E. coli

Fractalkine Protein, Cynomolgus, Rhesus, Recombinant (hFc)

TMPY-02415

Species: Cynomolgus,Rhesus

Expression System: HEK293

Fractalkine Protein, Canine, Recombinant (His)

TMPY-04665

Species: Canine

Expression System: HEK293

CXCL16 Protein, Canine, Recombinant (hFc)

TMPY-03896

Species: Canine

Expression System: HEK293

CXCL16 Protein, Rat, Recombinant (His)

TMPY-02754

Species: Rat

Expression System: HEK293

ACKR1 Protein, Human, Recombinant (His)

TMPH-00990

Species: Human

Expression System: in vitro E. coli expression system

CCL28 Protein, Human, Recombinant

TMPJ-00019

Species: Human

Expression System: E. coli

CCL16 Protein, Human, Recombinant

TMPJ-00018

Species: Human

Expression System: E. coli

Fractalkine Protein, Cynomolgus, Rhesus, Recombinant (His)

TMPY-04713

Species: Cynomolgus,Rhesus

Expression System: HEK293

CXCL16 Protein, Canine, Recombinant (His)

TMPY-03771

Species: Canine

Expression System: HEK293

IL-8/CXCL8 Protein, Canine, Recombinant

TMPY-03022

Species: Canine

Expression System: E. coli

SDF-1 Protein, Canine, Recombinant

TMPY-03580

Species: Canine

Expression System: E. coli

Dengue virus DENV-2 (strain New Guinea C) NS5 (methyltransferase domain)/Nonstructural protein 5 Protein (His)

TMPY-00279

Species: DENV

Expression System: E. coli

Eotaxin/CCL11 Protein, Human, Recombinant (His)

TMPY-02550

Species: Human

Expression System: E. coli

CCL21 Protein, Rhesus, Recombinant

TMPY-02828

Species: Rhesus

Expression System: Baculovirus-Insect Cells

CXCL6 Protein, Human, Recombinant (His)

TMPJ-01060

Species: Human

Expression System: Human Cells

IL-8/CXCL8 Protein, Rhesus, Recombinant

TMPY-03480

Species: Rhesus

Expression System: E. coli

CMKLR2 Protein, Rat, Recombinant (His)

TMPH-03265

Species: Rat

Expression System: in vitro E. coli expression system

FAM19A5 Protein, Human, Recombinant (His)

TMPK-00699

Species: Human

Expression System: E. coli

GRO beta/CXCL2 Protein, Rat, Recombinant

TMPY-00009

Species: Rat

Expression System: E. coli

CXCL1 Protein, Rat, Recombinant

TMPY-00008

Species: Rat

Expression System: E. coli

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Cat No.	Product Name
L7600	Chemokine Inhibitor Library	59 compounds
	A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening;
L5400	Anti-Cardiovascular Disease Compound Library	1428 compounds
	A unique collection of 1428 cardiovascular diseases related compounds for high throughput screening (HTS) and high content screening (HCS);

Libraries

Chemokine Inhibitor Library

L7600

Compounds: 59

Anti-Cardiovascular Disease Compound Library

L5400

Compounds: 1428