20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T17549 | Biotin-EDA | Others , PROTAC Linker | |
Biotin-EDA is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis. | |||
T39373 | PNU-EDA-Gly5 | PNU-EDA-Gly5 | |
PNU-EDA-Gly5 is a DNA topoisomerase I inhibitor-based oligo-glycine linker-payload used for the synthesis of antibody-drug conjugates (ADCs). It consists of the DNA topoisomerase I inhibitor PNU-159682 and the linker EDA... | |||
T18247 | Mal-C2-Gly3-EDA | Others | |
Mal-C2-Gly3-EDA is a cleavable antibody-drug conjugate (ADC) linker equipped with a Maleimide moiety. It serves the purpose of facilitating the synthesis of ADCs. | |||
T18246 | Mal-C2-Gly3-EDA-PNU-159682 | Others | |
Mal-C2-Gly3-EDA-PNU-159682, a drug-linker conjugate for antibody-drug conjugates (ADC), combines the cleavable ADC linker Mal-C2-Gly3-EDA with the potent ADC cytotoxin PNU-159682. | |||
T74555 | EDA-DA | ||
EDA-DA, an N-terminally tagged dipeptide probe, serves as a labeling agent for bacterial Peptidoglycan (PG), a fundamental component of the cell walls in most bacteria crucial for cellular division, shape retention, and ... | |||
T75354 | RH-EDA | ||
RH-EDA, a rhodamine-based turn-on fluorescent probe, detects hydroxyl radicals ([OH]) in living systems. | |||
T82842 | BODIPY FL EDA free base | ||
ODIPY FL EDA free base, an amine-based green fluorescent probe, possesses an R-NH2 group able to undergo coupling with aldehydes or ketones, forming reversible Schiff base adducts. These intermediates can be subsequently... | |||
T3862 | Irigenin | NF-κB , Integrin | |
Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra Domain A domain. It can sensitize TRAIL-induced apoptosis by enha... | |||
T24850 | Takeda103A | CMPD103A,Takeda-103A,Takeda-103-A,CMPD-103A,Takeda 103 A | GRK |
Takeda103A (CMPD103A) is the GRK2-dependent bovine tubulin oxidation effective inhibitor. | |||
TD0081 | EDANS | EDANS acid [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid],1,5-EDANS,EDANS acid [5-((2-Aminoethyl)amino)napht | Others |
EDANS (EDANS acid [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid]) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET). | |||
T13816 | (+)-Peusedanol | Others | |
(+)-Peusedanol is a natural product isolated from Peucedanumjaponicum. | |||
T38514 | PMEDAP | Others , HIV Protease | |
PMEDAP is a potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality and an inhibitor of human immunodeficiency virus (HIV) replication. PMEDAP also has anti-murine cytomega... | |||
T2585 | Bedaquiline | R207910,TMC207 | Antibacterial , Antibiotic |
Bedaquiline (R207910)(TMC207; R207910) is an anti-tuberculosis drug which selectively inhibit the mycobacterial energy metabolism i.e. ATP synthesis and found to be effective against all states of Mycobacterium tuberculo... | |||
T1073 | Dronedarone hydrochloride | Dronedarone HCl,SR33589 | Potassium Channel , Calcium Channel , Sodium Channel , Adrenergic Receptor , Autophagy |
Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation. | |||
T5763 | Sedanolide | Others , Autophagy | |
Sedanolide is a natural phthalide first isolated from seed oil of the Umbelliferae family, including celery. | |||
T34795 | Tedatioxetine | Lu AA 24530,Lu AA-24530,Lu AA24530 | |
Tedatioxetine (Lu AA24530) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) with antidepressant properties.Tedatioxetine acts as a CYP2D6 substrate. | |||
T3979 | Emedastine | LY188695,Emadine | Histamine Receptor |
Emedastine (LY188695) is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity. Emedastine reversibly and competitively blocks histamine by binding to H1 receptors, thus blocking its... | |||
T21023 | Bedaquiline fumarate | TMC 207,R403323,TMC-207,TMC207,R-403323,R 403323 | Antibacterial , Antibiotic |
Bedaquiline fumarate (TMC207), a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections. It blocks the proton pump for ATP synthase of mycobacteria. ... | |||
T6S0078 | Oxypeucedanin hydrate | Prangolarin Hydrate | Antioxidant |
1. Oxypeucedanin hydrate (Prangolarin Hydrate) has antioxidant activity. 2. Oxypeucedanin hydrate is an antimutagenic agent. 3. Oxypeucedanin hydrate exhibits carbohydrate metabolizing enzymes inhibitory effect. | |||
T23445 | Anxiolytic/nonsedative agent-1 | TCS 1205 | GABA Receptor |
Anxiolytic/nonsedative agent-1 (TCS 1205) is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for α1β2γ2, α... |