EDA

Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra Domain A domain. It can sensitize TRAIL-induced apoptosis by enhancing the expression of pro-apoptotic molecules in gastric cancer cells and has anti-cancer effects.

Pedaliin is a flavonoid extracted from the above-ground parts of sesame (Sesamum indicum L) and the Tibetan medicine Dracocephalum tanguticum Maxim.Pedaliin has shown antioxidant and anticancer effects against colon cancer in vitro, and can be used in the study of cardiovascular diseases.

Allosedamine is a useful organic compound for research related to life sciences and the catalog number is T131569.

(+)-Peusedanol is a natural product isolated from Peucedanumjaponicum.

1. Oxypeucedanin ((+-)-Oxypeucedanin) has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU145 cells. 2. Oxypeucedanin is a kind of open-channel blocker of the hKv1.5 channel and it prolongs the APD; therefore, it is an excellent candidate as an antiarrhythmic drug for atrial fibrillation.

Azedarachol possesses antifeedant activity.

Sedanolide is a natural phthalide first isolated from seed oil of the Umbelliferae family, including celery.

(-)-Oxypeucedanin hydrate is a furanocoumarin. It has a role as a metabolite.

1. Oxypeucedanin hydrate (Prangolarin Hydrate) has antioxidant activity. 2. Oxypeucedanin hydrate is an antimutagenic agent. 3. Oxypeucedanin hydrate exhibits carbohydrate metabolizing enzymes inhibitory effect.

(+)-Oxypeucedanin methanolate (compound 9) is a natural inhibitor of prostaglandin E2 production [1].

Peucedanoside A, a glycoside extracted from Peucedanum praeruptorum Dunn roots, demonstrates pharmaceutical potential [1].

Pedaliin 6''-acetate (compound 10), a natural product from Dracocephalum tanguticum, demonstrates antioxidative properties and cytoprotective effects against doxorubicin (DOX)-induced toxicity in H9c2 cardiomyocytes, with an EC50 of 19.1 μM [1].

(S)-7-O-Methylpeucedanol 3′-O-β-D-glucopyranoside is a coumarin glycoside [1].

Peucedanin is a natural product for research related to life sciences. The catalog number is TC0029 and the CAS number is 133-26-6.

Pedalitin is a mixed-type inhibitor of tyrosinase. In the assay of α-glucosidase inhibition, rosmarinic acid is a competitive inhibitor, whereas both methyl rosmarinate and Pedalitin are mixed-type inhibitors.

Hedamycin is an anthraquinone antibiotic exhibiting activity against Gram-positive bacteria, Gram-negative bacteria, mycobacteria, and yeasts (MIC of 0.031-3.2 μg/mL). It also inhibits rat duodenal adenocarcinoma, Walker 256 tumors in rats, HeLa cells, and the lysogenic Escherichia coli W1709 (λ) phage.

Cedarmycin B exhibits activity against Candida, Cryptococcus neoformans, and Aspergillus fumigatus, with a minimum inhibitory concentration (MIC) ranging from 12.5 to 50 μg/mL.

Chlorouvedalin is a natural product for research related to life sciences. The catalog number is TN3645 and the CAS number is 24694-80-2.

Peucedanocoumarin I is a natural product of Peucedanum, Apiaceae. The catalog number is TN4755 and the CAS number is 130464-55-0. Peucedanocoumarin I can be used as a reference standard.

Peucedanocoumarin II shows only partial relaxation.

Peucedanocoumarin Ⅲ can induce rice resistance to blast disease.

Peucedanol 3'-O-glucoside is a natural product for research related to life sciences. The catalog number is TN4758 and the CAS number is 65891-61-4.

Peucedanol 7-O-glucoside is a natural product for research related to life sciences. The catalog number is TN4759 and the CAS number is 65853-04-5.

Uvedalin shows cytotoxicity against HeLa, HL-60, and Murine B16-F10 melanoma cell lines.