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CaM

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    364
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    TargetMol | Inhibitors_Agonists
Autocamtide-2-related inhibitory peptide, myristoylated acetate(201422-04-0 free base)
TP1921L1
Autocamtide-2-related inhibitory peptide, myristoylated acetate is a CaM kinase II inhibitor; enhanced cell permeable derivative of Autocamtide-2-related inhibitory peptide.
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CaM kinase II inhibitor TFA salt
Autocamtide-2-related inhibitory peptide (TFA)
TP1216
CaM kinase II inhibitor TFA salt (Autocamtide-2-related inhibitory peptide (TFA)) is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.
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Autocamtide 2 TFA(129198-88-5 free base)
TP1217L
Autocamtide 2 TFA is a highly selective peptide substrate of calcium calmodulin-dependent protein kinase II (CaMKII). Autocamtide 2 TFA can be used in the CaMKII activity assay.
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Camstatin acetate
TP2057L
Camstatin acetate binds calmodulin and inhibits neuronal nitric oxide synthase. Camstatin acetate is a functionally active 25-residue fragment of the single calmodulin-binding IQ motif of PEP-19.
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Autocamtide-2-related inhibitory peptide
TP2310167114-91-2
Autocamtide-2-related inhibitory peptide is a potent and highly specific inhibitor of CaMKII, with an IC50 of 40 nM.
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CAM741
T70211177586-74-2
CAM741 is a novel selective inhibitor of vascular cell adhesion molecule 1 (VCAM1) synthesis in endothelial cells, blocking the process of cotranslational translocation, which is dependent on the signal peptide of VCAM1.
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10-14 weeks
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Onilcamotide
T385501164096-85-8
Onilcamotide, a cancer vaccine derived from the C-terminal peptide of the RhoC protein, exhibits potential immunomodulating and antineoplastic activities.
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Camstatin TFA
T75725
Camstatin TFA, a 25-residue fragment derived from the IQ motif of PEP-19, effectively binds to calmodulin and inhibits neuronal nitric oxide (NO) synthase, demonstrating its functional activity [1].
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Autocamtide-2-related inhibitory peptide TFA
T75736
Autocamtide-2-related inhibitory peptide (TFA) is a highly specific and potent CaMKII inhibitor with an IC50 value of 40 nM.
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Autocamtide-2-related inhibitory peptide, myristoylated TFA
T75737
Myristoylated Autocamtide-2-related inhibitory peptide, trifluoroacetic acid (TFA) form, is a potent and highly specific inhibitor of CaMKII, exhibiting an IC50 of 40 nM [1]. This compound constitutes the myristoylated variant of Autocamtide-2-related inhibitory peptide.
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Autocamtide-3
T76408142828-10-2
Autocamtide-3, a selective substrate for CaMKII (Ca2+ calmodulin-dependent kinase II) (CaMK), comprises a 13-amino-acid peptide featuring Thr287 [1].
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EcAMP3
T801472243219-65-8
EcAMP3, a hairpin-like peptide, exhibits both antifungal and antibacterial properties. It belongs to the EcAMP precursor family characterized by seven identical cysteine motifs: C1XXXC2(11–13)C3XXXC4 [1].
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cPcAMP1/26
T80282
cPcAMP1 26, an antimicrobial peptide, exhibits potent bactericidal activity against A. hydrophila and S. aureus by inducing depolarization of the bacterial plasma membrane and elevating intracellular ROS (Reactive Oxygen Species) levels [1].
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Autocamtide 2
Autocamtide II
TP1217129198-88-5
Autocamtide-2 is a highly selective peptide substrate for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family.
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Autocamtide 2, amide
TP1829
Autocamtide-2, amide is a highly selective peptide substrate for calcium calmodulin-dependent protein kinase II (CaMKII) assays (100 μM final concentration).
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Camstatin
TP20571002295-95-5
An analog of PEP-19 with enhanced binding to and antagonism of calmodulin.
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MLCK inhibitor peptide 18 acetate
MLCK inhibitor peptide 18 acetate(224579-74-2 free base)
TP1890L1
MLCK inhibitor peptide 18 acetate is a selective competitive inhibitor of myosin light chain kinase (IC50 = 50 nM). Displays 4000-fold selectivity over CaM kinase II and does not inhibit PKA. Cell permeable.
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CALP3 acetate(261969-05-5 free base)
TP1911L
CALP3 acetate is a potent Ca2+ channel blocker that activates EF hand motifs of Ca2+-binding proteins. CALP3 acetate can functionally mimic increased [Ca2+]i by modulating the activity of Calmodulin (CaM), Ca2+ channels and pumps.
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Syntide 2 TFA
T75754
Syntide 2 (TFA), a substrate peptide for Ca2+- and calmodulin (CaM)-dependent protein kinase II (CaMKII), selectively inhibits the gibberellin (GA) response without affecting constitutive and abscisic acid-regulated events [1].
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CALP2 TFA
T75790
CALP2 TFA, a potent calmodulin (CaM) antagonist with a dissociation constant (Kd) of 7.9 µM, exhibits high affinity for the CaM EF-hand Ca2+-binding site. This compound effectively inhibits CaM-dependent phosphodiesterase activity and elevates intracellular Ca2+ concentrations. Furthermore, it significantly hinders adhesion and degranulation, while also acting as a robust activator of alveolar macrophages [1] [2] [3] [4].
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CALP1 TFA
T75791
CALP1 TFA, a calmodulin (CaM) agonist with a dissociation constant (Kd) of 88 µM, selectively binds to the CaM EF-hand Ca2+-binding site, inhibiting calcium channel opening. This action blocks calcium influx and apoptosis with an IC50 of 44.78 µM, modulates glutamate receptor channel activity, and impedes a store-operated nonselective cation channel. Additionally, CALP1 TFA enhances CaM-dependent phosphodiesterase activity, denoting its multifaceted role in modulating cellular calcium dynamics [1] [2] [3] [4].
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Neurogranin (48-76), mouse
T76078
Neurogranin (48-76), mouse, is a peptide comprising residues 48-76 of Neurogranin, a post-synaptically exclusive calmodulin-binding protein that mediates NMDAR-driven synaptic plasticity by regulating the calcium-calmodulin (Ca2+-CaM) pathway [1].
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Calmodulin Dependent Protein Kinase Substrate Analog
T76487123067-01-6
Calmodulin-Dependent Protein Kinase Substrate Analog, a synthetic peptide substrate, is activated by Ca2+ and calmodulin (CaM). It serves as a substrate for protein kinases, leveraging a dependency on Ca2+ and CaM for its function [1].
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Calmodulin Dependent Protein Kinase Substrate
T7648882801-68-1
Calmodulin Dependent Protein Kinase Substrate is a synthetic peptide that interacts specifically with calmodulin-dependent protein kinases (CaMK) and requires calcium ions (Ca 2+) and calmodulin (CaM) for activation. It is utilized in studies involving protein kinase activity [1].
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